| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuerui Kong, Gaohe Dai, Zhong Zeng, Yi Zhang, Jiarong Gu, Teng Ma, Nina Wang, Jinhai Gu, Yin Wan. Integrating Proteomics and Transcriptomics Reveals the Potential Pathways of Hippocampal Neuron Apoptosis in Dravet Syndrome Model Mice. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674042. |
an important component contributing to the onset of epilepsy is the death of hippocampal neurons. |
2024-04-27 |
2024-04-29 |
mouse |
| Gabriel S Stephens, Jin Park, Andrew Eagle, Jason You, Manuel Silva-Pérez, Chia-Hsuan Fu, Sumin Choi, Corey P St Romain, Chiho Sugimoto, Shelly A Buffington, Yi Zheng, Mauro Costa-Mattioli, Yin Liu, A J Robison, Jeannie Chi. Persistent ∆FosB expression limits recurrent seizure activity and provides neuroprotection in the dentate gyrus of APP mice. Progress in neurobiology. 2024-04-20. PMID:38642602. |
recurrent seizures lead to accumulation of the activity-dependent transcription factor ∆fosb in hippocampal dentate granule cells in both mouse models of epilepsy and mouse models of alzheimer's disease (ad), which is also associated with increased incidence of seizures. |
2024-04-20 |
2024-04-23 |
mouse |
| Ryan M Jamiolkowski, Quynh-Anh Nguyen, Jordan S Farrell, Ryan J McGinn, David A Hartmann, Jeff J Nirschl, Mateo I Sanchez, Vivek P Buch, Ivan Soltes. The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy. Nature medicine. 2024-04-17. PMID:38632391. |
the fasciola cinereum of the hippocampal tail as an interventional target in epilepsy. |
2024-04-17 |
2024-04-20 |
mouse |
| Ryan M Jamiolkowski, Quynh-Anh Nguyen, Jordan S Farrell, Ryan J McGinn, David A Hartmann, Jeff J Nirschl, Mateo I Sanchez, Vivek P Buch, Ivan Soltes. The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy. Nature medicine. 2024-04-17. PMID:38632391. |
we identified the fasciola cinereum (fc) neurons of the posterior hippocampal tail as an important seizure node in both mice and humans with epilepsy. |
2024-04-17 |
2024-04-20 |
mouse |
| Dan Li, Na Sun, Yingying Guo, Shaoping Huang, Chunyan Yin, Yanfeng Xiao, Weijun M. Investigating the Effects of Perampanel on Autophagy-mediated Regulation of GluA2 and PSD95 in Epilepsy. Molecular neurobiology. 2024-04-11. PMID:38602656. |
primary mouse hippocampal neurons were cultured and subjected to an epilepsy cell model. |
2024-04-11 |
2024-04-13 |
mouse |
| Kristina K Zhang, Rafi Matin, Carolina Gorodetsky, George M Ibrahim, Flavia Venetucci Gouvei. Systematic review of rodent studies of deep brain stimulation for the treatment of neurological, developmental and neuropsychiatric disorders. Translational psychiatry. vol 14. issue 1. 2024-04-11. PMID:38605027. |
in dementia and epilepsy models, changes to cellular and molecular aspects of the hippocampus were shown to underlie symptom improvement. |
2024-04-11 |
2024-04-14 |
mouse |
| Cilla Zhou, Vaishali Satpute, Ka Lai Yip, Lyndsey L Anderson, Nicole Hawkins, Jennifer Kearney, Jonathon C Arnol. A high seizure burden increases several prostaglandin species in the hippocampus of a Scn1a Prostaglandins & other lipid mediators. 2024-04-10. PMID:38599513. |
a high seizure burden increases several prostaglandin species in the hippocampus of a scn1a dravet syndrome is an intractable epilepsy with a high seizure burden that is resistant to current anti-seizure medications. |
2024-04-10 |
2024-04-13 |
mouse |
| Dustin Fetterhoff, Manuela Costa, Robin Hellerstedt, Rebecca Johannessen, Lukas Imbach, Johannes Sarnthein, Bryan A Strang. Neuronal population representation of human emotional memory. Cell reports. vol 43. issue 4. 2024-04-09. PMID:38592973. |
we investigate how human medial temporal lobe (mtl) neurons support emotional memory by recording spiking activity from the hippocampus, amygdala, and entorhinal cortex during encoding and recognition sessions of an emotional memory task in patients with pharmaco-resistant epilepsy. |
2024-04-09 |
2024-04-12 |
human |
| Retraction: "Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway". Journal of cellular physiology. 2024-04-09. PMID:38591623. |
retraction: "silencing lncrna pvt1 inhibits activation of astrocytes and increases bdnf expression in hippocampus tissues of rats with epilepsy by downregulating the wnt signaling pathway". |
2024-04-09 |
2024-04-11 |
rat |
| Retraction: "Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway". Journal of cellular physiology. 2024-04-09. PMID:38591623. |
retraction: "silencing lncrna pvt1 inhibits activation of astrocytes and increases bdnf expression in hippocampus tissues of rats with epilepsy by downregulating the wnt signaling pathway", by teng zhao, ying ding, min li, chunkui zhou, and weihong lin, j cell physiol. |
2024-04-09 |
2024-04-11 |
rat |
| Jianfei Yan, Junjie Wu, Mingyue Xu, Min Wang, Weixiang Gu. Disrupted de novo pyrimidine biosynthesis impairs adult hippocampal neurogenesis and cognition in pyridoxine-dependent epilepsy. Science advances. vol 10. issue 14. 2024-04-08. PMID:38579001. |
disrupted de novo pyrimidine biosynthesis impairs adult hippocampal neurogenesis and cognition in pyridoxine-dependent epilepsy. |
2024-04-08 |
2024-04-10 |
Not clear |
| Yu Feng, Keziah S Diego, Zhe Dong, Zoé Christenson Wick, Lucia Page-Harley, Veronica Page-Harley, Julia Schnipper, Sophia I Lamsifer, Zachary T Pennington, Lauren M Vetere, Paul A Philipsberg, Ivan Soler, Albert Jurkowski, Christin J Rosado, Nadia N Khan, Denise J Cai, Tristan Shuma. Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559224. |
distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy. |
2024-04-01 |
2024-04-04 |
Not clear |
| Anli A Liu, William B Bar. Overlapping and distinct phenotypic profiles in Alzheimer's disease and late onset epilepsy: a biologically-based approach. Frontiers in neurology. vol 14. 2024-03-28. PMID:38545454. |
due to shared hippocampal dysfunction, patients with alzheimer's dementia and late-onset epilepsy (loe) report memory decline. |
2024-03-28 |
2024-03-30 |
Not clear |
| Piret Kleis, Enya Paschen, Ute Häussler, Carola A Haa. Low frequency stimulation for seizure suppression: Identification of optimal targets in the entorhinal-hippocampal circuit. Brain stimulation. 2024-03-26. PMID:38531502. |
mesial temporal lobe epilepsy (mtle) with hippocampal sclerosis (hs) is a common form of drug-resistant focal epilepsy in adults. |
2024-03-26 |
2024-03-29 |
mouse |
| Xue Liu, Fei-Yu Wang, Song Chi, Tao Liu, Hai-Lin Yang, Ru-Jie Zhong, Xiao-Yu Li, Jing Ga. Mitochondria-targeting peptide SS-31 attenuates ferroptosis via inhibition of the p38 MAPK signaling pathway in the hippocampus of epileptic rats. Brain research. 2024-03-23. PMID:38521160. |
our results demonstrated that the rat hippocampal neurons after epilepsy were followed by accumulated iron and malondialdehyde (mda) content, upregulated phosphorylated p38 mapk protein (p-p38) and nuclear factor erythroid 2-related factor 2 (nrf2) levels, reduced glutathione peroxidase 4 (gpx4) content, and depleted glutathione (gsh) activity. |
2024-03-23 |
2024-03-26 |
rat |
| Robert J Carton, Michael G Doyle, Hugh Kearney, Charles A Steward, Nicholas J Lench, Anthony Rogers, Erin L Heinzen, Seamus McDonald, Joanna Fay, Austin Lacey, Alan Beausang, Jane Cryan, Francesca Brett, Hany El-Naggar, Peter Widdess-Walsh, Daniel Costello, Ronan Kilbride, Colin P Doherty, Kieron J Sweeney, Donncha F O'Brien, David C Henshall, Norman Delanty, Gianpiero L Cavalleri, Katherine A Benso. Somatic variants as a cause of drug-resistant epilepsy including mesial temporal lobe epilepsy with hippocampal sclerosis. Epilepsia. 2024-03-16. PMID:38491957. |
somatic variants as a cause of drug-resistant epilepsy including mesial temporal lobe epilepsy with hippocampal sclerosis. |
2024-03-16 |
2024-03-19 |
Not clear |
| Liesbeth François, Alessia Romagnolo, Mark J Luinenburg, Jasper J Anink, Patrice Godard, Marek Rajman, Jonathan van Eyll, Angelika Mühlebner, Andrew Skelton, James D Mills, Stefanie Dedeurwaerdere, Eleonora Aronic. Identification of gene regulatory networks affected across drug-resistant epilepsies. Nature communications. vol 15. issue 1. 2024-03-12. PMID:38467626. |
this study included the most common drug-resistant epilepsies (dres), such as temporal lobe epilepsy with hippocampal sclerosis (tle-hs), and mtor pathway-related malformations of cortical development (mtoropathies). |
2024-03-12 |
2024-03-14 |
Not clear |
| Meysam Zare, Mahmoud Rezaei, Milad Nazari, Nastaran Kosarmadar, Mona Faraz, Victoria Barkley, Amir Shojaei, Mohammad Reza Raoufy, Javad Mirnajafi-Zade. Effect of the closed-loop hippocampal low-frequency stimulation on seizure severity, learning, and memory in pilocarpine epilepsy rat model. CNS neuroscience & therapeutics. vol 30. issue 3. 2024-03-05. PMID:38439573. |
effect of the closed-loop hippocampal low-frequency stimulation on seizure severity, learning, and memory in pilocarpine epilepsy rat model. |
2024-03-05 |
2024-03-07 |
rat |
| Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A Cihangir Uğuz, Enes Akyü. Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model. Synapse (New York, N.Y.). vol 78. issue 2. 2024-03-04. PMID:38436644. |
gender-related variation expressions of neuroplastin traf6, glua1, gaba(a) receptor, and pmca in cortex, hippocampus, and brainstem in an experimental epilepsy model. |
2024-03-04 |
2024-03-06 |
rat |
| Yueying Liu, Yuanjin Chang, Xiaofan Jiang, Huiya Mei, Yingsi Cao, Dongqin Wu, Ruijin Xie, Wenjun Jiang, Emely Vasquez, Yu Wu, Shunyan Lin, Yachuan Ca. Analysis of the role of PANoptosis in seizures via integrated bioinformatics analysis and experimental validation. Heliyon. vol 10. issue 4. 2024-02-26. PMID:38404827. |
epilepsy is recognized as the most common chronic neurological condition among children, and hippocampal neuronal cell death has been identified as a crucial factor in the pathophysiological processes underlying seizures. |
2024-02-26 |
2024-02-28 |
Not clear |