| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaotong Zhang, Yanyun Feng, Zhuoming Chen, Jinyi Lon. Altered functional connecticity in the hippocampal and striatal systems after motor sequence learning consolidation in medial temporal lobe epilepsy individuals. Journal of neurophysiology. 2024-01-17. PMID:38230870. |
to better understand the functional performance within these two systems under the pathological condition of hippocampal impairment, we compared the functional differences after consolidation between patients with left medial temporal epilepsy (lmtle) and healthy controls (hcs). |
2024-01-17 |
2024-01-19 |
human |
| Sang Kun Le. Who are the Better Candidates for Epilepsy Surgery? Journal of epilepsy research. vol 13. issue 2. 2024-01-15. PMID:38223357. |
the better surgical candidates for epilepsy surgery are the followings: patients displaying a discrete lesion on mri with concordant video-eeg monitoring (vem) results, patients diagnosed with unilateral hippocampal sclerosis who have concordant vem results, patients with unilateral hippocampal sclerosis but discordant vem results, patients with focal cortical dysplasia and concordant vem results, and patients diagnosed with mr-negative tle who exhibit two or more consistent results from presurgical evaluations. |
2024-01-15 |
2024-01-17 |
Not clear |
| Xiaoke Wu, Mengmeng Shi, Yuan Chen, Yajun Lian, Shaokuan Fang, Haifeng Zhan. Effect and Mechanism of LIN28 on Ferroptosis in Mg Neurochemical research. 2024-01-13. PMID:38217758. |
in this study, we established an epilepsy model by culturing hippocampal neurons from rats in a magnesium-free (mg |
2024-01-13 |
2024-01-16 |
rat |
| Vanda Tukacs, Dániel Mittli, Éva Hunyadi-Gulyás, Zsuzsanna Darula, Gábor Juhász, József Kardos, Katalin Adrienna Kékes. Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats. Fluids and barriers of the CNS. vol 21. issue 1. 2024-01-11. PMID:38212833. |
thus, we applied a 4-aminopyridine (4-ap) epilepsy model to study the hippocampal ecf peptidome alterations upon treatment in rats. |
2024-01-11 |
2024-01-14 |
rat |
| Maria A Tikhonova, Anna A Shvaikovskaya, Svetlana Y Zhanaeva, Galina I Moysak, Anna A Akopyan, Jamil A Rzaev, Konstantin V Danilenko, Lyubomir I Aftana. Concordance between the In Vivo Content of Neurospecific Proteins (BDNF, NSE, VILIP-1, S100B) in the Hippocampus and Blood in Patients with Epilepsy. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203674. |
concordance between the in vivo content of neurospecific proteins (bdnf, nse, vilip-1, s100b) in the hippocampus and blood in patients with epilepsy. |
2024-01-11 |
2024-01-13 |
human |
| Maria A Tikhonova, Anna A Shvaikovskaya, Svetlana Y Zhanaeva, Galina I Moysak, Anna A Akopyan, Jamil A Rzaev, Konstantin V Danilenko, Lyubomir I Aftana. Concordance between the In Vivo Content of Neurospecific Proteins (BDNF, NSE, VILIP-1, S100B) in the Hippocampus and Blood in Patients with Epilepsy. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203674. |
this study aimed to assess the correspondence of the expression of bdnf, nse, vilip-1, and s100b in the blood (serum and peripheral blood mononuclear cells (pbmcs)) to the in vivo hippocampal levels of subjects with drug-resistant epilepsy who underwent neurosurgery (n = 44) using multiplex solid-phase analysis, elisa, and immunohistochemical methods, as well as to analyze the correlations and associations of the blood and hippocampal levels of these proteins with clinical parameters. |
2024-01-11 |
2024-01-13 |
human |
| Marijke Vergaelen, Simona Manzella, Kristl Vonck, Erine Craey, Jeroen Spanoghe, Mathieu Sprengers, Evelien Carrette, Wytse Jan Wadman, Jean Delbeke, Paul Boon, Lars Emil Larsen, Robrecht Raed. Increased Dentate Gyrus Excitability in the Intrahippocampal Kainic Acid Mouse Model for Temporal Lobe Epilepsy. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203829. |
the purpose of this study was to electrophysiologically characterize the excitability of hippocampal subregions in the chronic phase of the induced epilepsy in the ihka mouse model. |
2024-01-11 |
2024-01-13 |
mouse |
| Ruben Carvalho, Alisa N Lukoyanova, João Casalta-Lopes, Nikolay V Lukoyanov, Joana Isabel Soare. Plastic rearrangement of basal forebrain parvalbumin-immunoreactive neurons in the kainite model of epilepsy. AIMS neuroscience. vol 10. issue 4. 2024-01-08. PMID:38188006. |
however, little is known about the involvement of the basal forebrain gabaergic neurons in epilepsy; despite this, they largely project to the temporal lobe and are crucial for the regulation of the hippocampal circuitry. |
2024-01-08 |
2024-01-10 |
rat |
| Jana Desloovere, Paul Boon, Lars Emil Larsen, Marie-Gabrielle Goossens, Jean Delbeke, Evelien Carrette, Wytse Wadman, Kristl Vonck, Robrecht Raed. Chemogenetic Seizure Control with Clozapine and the Novel Ligand JHU37160 Outperforms the Effects of Levetiracetam in the Intrahippocampal Kainic Acid Mouse Model. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 19. issue 1. 2024-01-04. PMID:38176801. |
expression of inhibitory designer receptors exclusively activated by designer drugs (dreadds) on excitatory hippocampal neurons in the hippocampus represents a potential new therapeutic strategy for drug-resistant epilepsy. |
2024-01-04 |
2024-01-07 |
mouse |
| Hael F Abdulrazeq, Anna R Kimata, Belinda Shao, Konstantina Svokos, Neishay Ayub, Duyu Nie, Wael F Asaa. Laser amygdalohippocampotomy reduces contralateral hippocampal sub-clinical activity in bitemporal epilepsy: A case illustration of responsive neurostimulator ambulatory recordings. Epilepsy & behavior reports. vol 25. 2024-01-01. PMID:38162813. |
laser amygdalohippocampotomy reduces contralateral hippocampal sub-clinical activity in bitemporal epilepsy: a case illustration of responsive neurostimulator ambulatory recordings. |
2024-01-01 |
2024-01-05 |
Not clear |
| Letícia Meier, Estevan Bruginski, Joseane Righes Marafiga, Letícia Barbieri Caus, Mayara Vendramin Pasquetti, Maria Elisa Calcagnotto, Francinete Ramos Campo. Hippocampal metabolic profile during epileptogenesis in the pilocarpine model of epilepsy. Biomedical chromatography : BMC. 2023-12-28. PMID:38154955. |
hippocampal metabolic profile during epileptogenesis in the pilocarpine model of epilepsy. |
2023-12-28 |
2023-12-31 |
Not clear |
| Letícia Meier, Estevan Bruginski, Joseane Righes Marafiga, Letícia Barbieri Caus, Mayara Vendramin Pasquetti, Maria Elisa Calcagnotto, Francinete Ramos Campo. Hippocampal metabolic profile during epileptogenesis in the pilocarpine model of epilepsy. Biomedical chromatography : BMC. 2023-12-28. PMID:38154955. |
with these findings, we provided an overview of hippocampal metabolic profiles during different stages of epileptogenesis that could help investigate pathways and respective metabolites as predictive tools in epilepsy. |
2023-12-28 |
2023-12-31 |
Not clear |
| Isotta Rigoni, Guru Prasad Padmasola, Laurent Sheybani, Karl Schaller, Charles Quairiaux, Serge Vulliemo. Reproducible network changes occur in a mouse model of temporal lobe epilepsy but do not correlate with disease severity. Neurobiology of disease. 2023-12-19. PMID:38114050. |
here, we used the unilateral, kainate mouse model of hippocampal epilepsy to investigate brain network changes before and after epilepsy onset and their stability across time. |
2023-12-19 |
2023-12-23 |
mouse |
| Gregory R Lum, Sung Min Ha, Christine A Olson, Montgomery Blencowe, Jorge Paramo, Beck Reyes, Joyce H Matsumoto, Xia Yang, Elaine Y Hsia. Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice. Cell reports. vol 42. issue 12. 2023-12-09. PMID:38070135. |
mice colonized with kd-associated gut microbes exhibit altered hippocampal transcriptomes, including pathways related to atp synthesis, glutathione metabolism, and oxidative phosphorylation, and are linked to susceptibility genes identified in human epilepsy. |
2023-12-09 |
2023-12-17 |
mouse |
| Michelle C Gulfo, Joseph J Lebowitz, Czarina Ramos, Dong-Woo Hwang, Kaoutsar Nasrallah, Pablo E Castill. Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 50. 2023-12-08. PMID:38064513. |
hilar mossy cells (mcs) are principal excitatory neurons of the dentate gyrus (dg) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety and epilepsy. |
2023-12-08 |
2023-12-17 |
Not clear |
| Mojde Nahtani, Mehdi Siahi, Javad Razjouya. Astrocytic-based Controller Shifts Epileptic Activity to the Chaotic State. Basic and clinical neuroscience. vol 14. issue 4. 2023-12-05. PMID:38050566. |
investigating an effective controller to shift hippocampal epileptic periodicity to normal chaotic behavior will be new hope for epilepsy treatment. |
2023-12-05 |
2023-12-10 |
Not clear |
| Wenrong Wen, Jingsheng Zhou, Chang'an Zhan, Jun Wan. Microglia as a Game Changer in Epilepsy Comorbid Depression. Molecular neurobiology. 2023-12-04. PMID:38048030. |
activated microglia released cytokines like il-6 and il-1β, orchestrating neuroinflammation especially in the hippocampus, worsening both depression and epilepsy. |
2023-12-04 |
2023-12-10 |
Not clear |
| Giulia Natali, Caterina Michetti, Alicja Krawczun-Rygmaczewska, Thomas Floss, Fabrizia Cesca, Fabio Benfenat. Conditional knockout of REST/NRSF in excitatory neurons reduces seizure susceptibility to chemical kindling. Frontiers in cellular neuroscience. vol 17. 2023-11-30. PMID:38034589. |
as forebrain excitatory neurons are the common final pathway of seizure susceptibility, we investigated the role of rest in epilepsy by inducing rest conditional knockout (rest-cko) specifically in excitatory neurons of the hippocampus. |
2023-11-30 |
2023-12-10 |
Not clear |
| Angelo Labate, Salvatore Bertino, Rosa Morabito, Chiara Smorto, Annalisa Militi, Simona Cammaroto, Carmelo Anfuso, Francesco Tomaiuolo, Paolo Tonin, Silvia Marino, Antonio Cerasa, Angelo Quartaron. MR-Guided Focused Ultrasound for Refractory Epilepsy: Where Are We Now? Journal of clinical medicine. vol 12. issue 22. 2023-11-25. PMID:38002683. |
taken together, the available studies support a possible role for lesional treatment over the anterior thalamus with high-intensity ultrasound and neuromodulation of the hippocampus via low-intensity ultrasound in refractory epilepsy. |
2023-11-25 |
2023-11-28 |
Not clear |
| Gabriele Zanirati, Padmashri A Shetty, Ashok K Shett. Neural Stem Cells Persist to Generate New Neurons in the Hippocampus of Adult and Aged Human Brain - Fiction or Accurate? Ageing research reviews. 2023-11-24. PMID:38000512. |
while the existence of robust neurogenesis in the adult and aged human hippocampus is yet to be confirmed, this review highlights evidence from a significant number of studies supporting the persistence of hippocampal neurogenesis during adulthood and aging in humans, including in some neurological conditions, such as epilepsy and alzheimer's disease. |
2023-11-24 |
2023-11-28 |
human |