| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daichi Sone, Iman Beheshti, Yoko Shigemoto, Yukio Kimura, Noriko Sato, Hiroshi Matsud. White matter brain-age in diverse forms of epilepsy and interictal psychosis. Scientific reports. vol 14. issue 1. 2024-08-19. PMID:39160281. |
as a result, almost all epilepsy categories showed significantly increased brain-pad (p < 0.001), including temporal lobe epilepsy (tle) with no mri-lesion (+ 4.2 yr), tle with hippocampal sclerosis (+ 9.1 yr), extratemporal focal epilepsy (+ 5.1 yr), epileptic encephalopathy or progressive myoclonus epilepsy (+ 18.4 yr), except for idiopathic generalized epilepsy (ige). |
2024-08-19 |
2024-08-22 |
human |
| Rhuann Pontes Dos Santos Silva, Isabella Carla Barbosa Lima Angelo, Guilherme Cavalcanti De Medeiros Dantas, Joana Martins De Souza, João Ricardo Caldas Pinheiro Pessoa, Laura Guerra Lopes, João Paulo Mota Telles, Wagner Gonçalves Hort. Pattern of abnormalities on gray matter in patients with medial temporal lobe epilepsy and hippocampal sclerosis: An updated meta-analysis. Clinical neurology and neurosurgery. vol 245. 2024-08-18. PMID:39154538. |
a common pathological feature is hippocampal sclerosis (hs), characterized by the loss of neuronal cells, which is associated with the typical temporal mesial lobe epilepsy (mtle). |
2024-08-18 |
2024-08-21 |
Not clear |
| Jiao Yang, Ji-Heng Cai, Tong-Xuan Wu, Zhi-Qiang Gao, Chao Zhou, Qi Wu, Miao-Jin J. Salvinorin A ameliorates pilocarpine-induced seizures by regulating hippocampal microglia polarization. Journal of ethnopharmacology. 2024-08-18. PMID:39154669. |
considering the anti-inflammatory effect of s. divinorum and endogenous hippocampal dynorphin/ kappa opioid receptor (kor) system playing an anticonvulsant function, we hypothesis that sal a can be a potential candidate to treat epilepsy. |
2024-08-18 |
2024-08-21 |
Not clear |
| Jennifer M Yonan, Kevin D Chen, Tallie Z Baram, Oswald Stewar. PTEN Deletion in the Adult Dentate Gyrus Induces Epilepsy. bioRxiv : the preprint server for biology. 2024-08-16. PMID:39149280. |
pten-deletion provoked epilepsy was not associated with apparent hippocampal neuron death; supra-granular mossy fiber sprouting was observed in a few mice. |
2024-08-16 |
2024-08-18 |
mouse |
| Aileen Harnett, Justine Mathoux, Marc-Michel Wilson, Mona Heiland, Omar Mamad, Sujithra Srinivas, Albert Sanfeliu, Amaya Sanz-Rodriguez, Kelvin Lau E How, Norman Delanty, Jane Cryan, Francesca M Brett, Michael A Farrell, Donncha F O'Brien, David C Henshall, Gary P Brenna. Impact of JQ1 treatment on seizures, hippocampal gene expression, and gliosis in a mouse model of temporal lobe epilepsy. The European journal of neuroscience. 2024-08-16. PMID:39149798. |
despite influencing early aspects of epileptogenesis, blocking bet protein activity with jq1 had no overt effects on epilepsy development in mice but did alter glial reactivity and influence gene expression patterns, promoting various neurotransmitter signalling mechanisms and inflammatory pathways in the hippocampus. |
2024-08-16 |
2024-08-18 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
pvt1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by mir-206-3p-dependent regulation of camk4. |
2024-08-14 |
2024-08-16 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
this study was designed to dissect the function of plasmacytoma variant translocation 1 (pvt1) in hippocampal neuron injury in epilepsy and its possible molecular basis. |
2024-08-14 |
2024-08-16 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
collectively, pvt1 contributed to se-induced apoptosis and inflammation in hippocampal neurons by modulating the mir-206-3p/camk4 axis, offering a novel insight into the prevention of epilepsy. |
2024-08-14 |
2024-08-16 |
mouse |
| Rudhab Bahabry, Rebecca M Hauser, Richard G Sánchez, Silvienne Sint Jago, Lara Ianov, Remy J Stuckey, R Ryley Parrish, Lawrence Ver Hoef, Farah D Lubi. Alterations in DNA 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsy. Neurobiology of disease. 2024-08-14. PMID:39142613. |
alterations in dna 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsy. |
2024-08-14 |
2024-08-17 |
human |
| Rudhab Bahabry, Rebecca M Hauser, Richard G Sánchez, Silvienne Sint Jago, Lara Ianov, Remy J Stuckey, R Ryley Parrish, Lawrence Ver Hoef, Farah D Lubi. Alterations in DNA 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsy. Neurobiology of disease. 2024-08-14. PMID:39142613. |
temporal lobe epilepsy (tle) is a type of focal epilepsy characterized by spontaneous recurrent seizures originating from the hippocampus. |
2024-08-14 |
2024-08-17 |
human |
| Gregory Lepeu, Ellen van Maren, Kristina Slabeva, Cecilia Friedrichs-Maeder, Markus Fuchs, Werner J Z'Graggen, Claudio Pollo, Kaspar A Schindler, Antoine Adamantidis, Timothée Proix, Maxime O Bau. The critical dynamics of hippocampal seizures. Nature communications. vol 15. issue 1. 2024-08-13. PMID:39138153. |
here, we verified that predictions on bifurcations applied to the onset of hippocampal seizures, providing concordant results from in silico modeling, optogenetics experiments in male mice and intracranial eeg recordings in human patients with epilepsy. |
2024-08-13 |
2024-08-16 |
human |
| Anton V Chizhov, Vasilii S Tiselko, Tatyana Yu Postnikova, Aleksey V Zaitse. Phase-Dependent Response to Electrical Stimulation of Cortical Networks during Recurrent Epileptiform Short Discharge Generation In Vitro. International journal of molecular sciences. vol 25. issue 15. 2024-08-10. PMID:39125856. |
in this study, we investigated the sensitivity of continuous epileptiform short discharge generation to electrical stimulation applied at different phases between the discharges using an in vitro 4-ap-based model of epilepsy in rat hippocampal slices. |
2024-08-10 |
2024-08-13 |
rat |
| Tania Ramos-Moreno, Alexandra Cifra, Nikitidou Ledri Litsa, Esbjörn Melin, Matilda Ahl, Sören H Christiansen, Casper R Gøtzsche, Matilde Cescon, Paolo Bonaldo, Karen van Loo, Valeri Borger, J Anink Jasper, Albert Becker, Erwin A van Vliet, Eleonora Aronica, David P Woldbye, Merab Kokai. Collagen VI: Role in synaptic transmission and seizure-related excitability. Experimental neurology. 2024-08-02. PMID:39094767. |
in the present study we report increased mrna and protein expression of col-vi in the hippocampus and cortex at a late stage of epileptogenesis in a post-status epilepticus (se) model of epilepsy and in brain tissue from patients with epilepsy. |
2024-08-02 |
2024-08-06 |
mouse |
| AnnaLin M Woo, Harald Sontheime. Interactions between astrocytes and extracellular matrix structures contribute to neuroinflammation-associated epilepsy pathology. Frontiers in molecular medicine. vol 3. 2024-08-01. PMID:39086689. |
we offer epilepsy as a well-studied neurological disorder in which there is clear evidence of astrocyte contribution to diseases as evidenced across several different disease models, including mouse models of hippocampal sclerosis, trauma associated epilepsy, glioma-associated epilepsy, and beta-1 integrin knockout astrogliosis. |
2024-08-01 |
2024-08-03 |
mouse |
| Mahan Farzan, Behnaz Abedi, Iman Bhia, Atossa Madanipour, Mahour Farzan, Mohammad Bhia, Ava Aghaei, Iman Kheirollahi, Mahzad Motallebi, Hossein Amini-Khoei, Yavuz Nuri Erta. Pharmacological Activities and Molecular Mechanisms of Sinapic Acid in Neurological Disorders. ACS chemical neuroscience. 2024-07-31. PMID:39082749. |
these effects also include neuroprotection in epilepsy models, as evidenced by a reduction in seizure-like behavior, cell death in specific hippocampal regions, and lowered neuroinflammatory markers. |
2024-07-31 |
2024-08-02 |
Not clear |
| Nishard Abdee. Editorial for "Hippocampal Glutamate Levels and Their Correlation With Subregion Volume in School-Aged Children With MRI-Negative Epilepsy: A Preliminary Study". Journal of magnetic resonance imaging : JMRI. 2024-07-30. PMID:39078258. |
editorial for "hippocampal glutamate levels and their correlation with subregion volume in school-aged children with mri-negative epilepsy: a preliminary study". |
2024-07-30 |
2024-08-02 |
Not clear |
| Tatyana Y Postnikova, Georgy P Diespirov, Sergey L Malkin, Alexander S Chernyshev, Elizaveta N Vylekzhanina, Aleksey V Zaitse. Morphological and Functional Alterations in the CA1 Pyramidal Neurons of the Rat Hippocampus in the Chronic Phase of the Lithium-Pilocarpine Model of Epilepsy. International journal of molecular sciences. vol 25. issue 14. 2024-07-27. PMID:39062811. |
morphological and functional alterations in the ca1 pyramidal neurons of the rat hippocampus in the chronic phase of the lithium-pilocarpine model of epilepsy. |
2024-07-27 |
2024-07-29 |
rat |
| J Chvojka, J Kudláček, K Liska, A Pant, J Gr Jefferys, P Jirusk. Dissociation Between the Epileptogenic Lesion and Primary Seizure Onset Zone in the Tetanus Toxin Model of Temporal Lobe Epilepsy. Physiological research. vol 73. issue 3. 2024-07-19. PMID:39027960. |
epilepsy was induced by injecting a minute dose of tetanus toxin into the right dorsal hippocampus in seven animals. |
2024-07-19 |
2024-07-21 |
Not clear |
| Ankit N Khambhati, Edward F Chang, Maxime O Baud, Vikram R Ra. Hippocampal network activity forecasts epileptic seizures. Nature medicine. 2024-07-12. PMID:38997606. |
in this retrospective cohort study of 15 adults with bitemporal epilepsy who had a device that provides chronic intracranial recordings, functional connectivity of hippocampal networks fluctuated in multiday cycles with patterns that mirrored cycles of seizure likelihood. |
2024-07-12 |
2024-07-15 |
Not clear |
| Donghao Xu, Qingfa Ren, Quanyuan Liu, Miaomiao Liu, He Gong, Yuwei Liu, Zhijie Yin, Zhen Zeng, Shuyuan Xia, Yanyan Zhang, Jie Li, Quansheng Gao, Jing Wang, Xianglin L. Hippocampal Glutamate Levels and Their Correlation With Subregion Volume in School-Aged Children With MRI-Negative Epilepsy: A Preliminary Study. Journal of magnetic resonance imaging : JMRI. 2024-07-06. PMID:38970314. |
hippocampal glutamate levels and their correlation with subregion volume in school-aged children with mri-negative epilepsy: a preliminary study. |
2024-07-06 |
2024-07-12 |
Not clear |