| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amany Mohamed Shalaby, Heba E M Sharaf Eldin, Ahmed Ahmed Abdelsameea, Hanim Magdy Abdelnour, Mohamed Ali Alabiad, Mahmoud Ramadan Elkholy, Adel Mohamed Aboregel. Betahistine Attenuates Seizures, Neurodegeneration, Apoptosis, and Gliosis in the Cerebral Cortex and Hippocampus in a Mouse Model of Epilepsy: A Histological, Immunohistochemical, and Biochemical Study. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 2022-06-10. PMID:35686434. |
betahistine attenuates seizures, neurodegeneration, apoptosis, and gliosis in the cerebral cortex and hippocampus in a mouse model of epilepsy: a histological, immunohistochemical, and biochemical study. |
2022-06-10 |
2023-08-14 |
mouse |
| Kun-Mei Liu, Yue Huang, Pan-Pan Wan, Yun-Hua Lu, Ning Zhou, Juan-Juan Li, Chun-Yang Yu, Jin-Jiang Chou, Lianxiang Zhang, Chun Zhang, Yuan-Yuan Qiang, Rui Zhang, Le Gu. Ursolic Acid Protects Neurons in Temporal Lobe Epilepsy and Cognitive Impairment by Repressing Inflammation and Oxidation. Frontiers in pharmacology. vol 13. 2022-06-09. PMID:35677445. |
moreover, ua treatment rescued hippocampal neuronal damage, aberrant neurogenesis, and ectopic migration, which are commonly accompanied by epilepsy occurrence. |
2022-06-09 |
2023-08-14 |
rat |
| Hanmu Guo, Lexin Zheng, Heng Xu, Qiuyu Pang, Zhiyang Ren, Yuan Gao, Tao Wan. Neurobiological Links between Stress, Brain Injury, and Disease. Oxidative medicine and cellular longevity. vol 2022. 2022-06-06. PMID:35663199. |
this review summarizes various stress models and their applications and then discusses the effects and mechanisms of stress on key brain regions-including the hippocampus, hypothalamus, amygdala, and prefrontal cortex-and in brain injuries and diseases-including alzheimer's disease, stroke, traumatic brain injury, and epilepsy. |
2022-06-06 |
2023-08-14 |
Not clear |
| Qin Zhou, Qiong Wang, Baomei He, Haibo Kong, Huanjun Luo, Xiaowei Wang, Wenlan Wan. MicroRNA 322-5p reduced neuronal inflammation via the TLR4/TRAF6/NF-κB axis in a rat epilepsy model. Open medicine (Warsaw, Poland). vol 17. issue 1. 2022-06-01. PMID:35647304. |
exogenous mir-322-5p reduced the expression of inflammatory molecules and increased the gaba levels in se rats, and also reduced hippocampal neuronal cell apoptosis caused by epilepsy. |
2022-06-01 |
2023-08-13 |
rat |
| Ilia G Komoltsev, Natalia V Gulyaev. Brain Trauma, Glucocorticoids and Neuroinflammation: Dangerous Liaisons for the Hippocampus. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625876. |
these mechanisms are applicable to remote hippocampal damage occurring after other types of focal brain damage (stroke, epilepsy) or central nervous system diseases without obvious focal injury. |
2022-05-28 |
2023-08-13 |
Not clear |
| Dongsheng Gao, Linqing Ma, Yunliang Xie, Bo Xiao, Shouru Xue, Wenbiao Xiao, You Zhou, Xiuying Cai, Xiaoyan Yan. Electroacupuncture Promotes Autophagy by Regulating the AKT/mTOR Signaling Pathway in Temporal Lobe Epilepsy. Neurochemical research. 2022-05-27. PMID:35622215. |
therefore, this study suggested that ea promoted autophagy in hippocampal neurons during the onset of epilepsy by regulating the akt/mtor signaling pathway to treat epilepsy. |
2022-05-27 |
2023-08-13 |
rat |
| Artur Vetkas, Jürgen Germann, Gavin Elias, Aaron Loh, Alexandre Boutet, Kazuaki Yamamoto, Can Sarica, Nardin Samuel, Vanessa Milano, Anton Fomenko, Brendan Santyr, Jordy Tasserie, Dave Gwun, Hyun Ho Jung, Taufik Valiante, George M Ibrahim, Richard Wennberg, Suneil K Kalia, Andres M Lozan. Identifying the neural network for neuromodulation in epilepsy through connectomics and graphs. Brain communications. vol 4. issue 3. 2022-05-25. PMID:35611305. |
to pinpoint specific regions in the normative epilepsy deep brain stimulation network, we examined overlapping areas of functional connectivity between the anterior thalamic nucleus, centromedian thalamic nucleus, hippocampus and less studied epilepsy deep brain stimulation targets. |
2022-05-25 |
2023-08-13 |
Not clear |
| Chunlong Mu, Thomas A Tompkins, Jong M Rho, Morris H Scantlebury, Jane Sheare. Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy. Biochimica et biophysica acta. Molecular basis of disease. 2022-05-19. PMID:35589071. |
gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy. |
2022-05-19 |
2023-08-13 |
rat |
| Duk-Shin Lee, Tae-Hyun Kim, Hana Park, Ji-Eun Ki. CDDO-Me Attenuates Clasmatodendrosis in CA1 Astrocyte by Inhibiting HSP25-AKT Mediated DRP1-S637 Phosphorylation in Chronic Epilepsy Rats. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35562960. |
in the present study, we found that clasmatodendritic astrocytes showed up-regulations of hsp25 expression, akt serine (s) 473 and dynamin-related protein 1 (drp1) s637 phosphorylations in the hippocampus of chronic epilepsy rats. |
2022-05-14 |
2023-08-13 |
rat |
| Mohammad Amin Manav. Neuroprotective effects of glucagon-like peptide-1 (GLP-1) analogues in epilepsy and associated comorbidities. Neuropeptides. vol 94. 2022-05-13. PMID:35561568. |
on the other hand, glp-1 receptors are located throughout the brain, including the hippocampus, which have been associated to majority of neurological conditions, such as epilepsy and psychiatric disorders. |
2022-05-13 |
2023-08-13 |
Not clear |
| Jorge Pinheiro, Mrinalini Honava. Focal cortical dysplasia: Updates. Indian journal of pathology & microbiology. vol 65. issue Supplement. 2022-05-13. PMID:35562149. |
focal cortical dysplasias (fcds) represent the third most frequent cause of drug-resistant focal epilepsy in adults (after hippocampal sclerosis and tumours) submitted to surgery, and the most common in the pediatric age group. |
2022-05-13 |
2023-08-13 |
Not clear |
| Jingbo Wei, Hui Liu, Ziqi Liu, Xiaohua Jiang, Weiping Wan. The Temporal and Spatial Changes of Th17, Tregs, and Related Cytokines in Epilepsy Lesions. Applied bionics and biomechanics. vol 2022. 2022-05-09. PMID:35528532. |
results showed that th17 and its related cytokines in epilepsy lesions played a role mainly at acute phase of epilepsy, and they were positively correlated with the pathological changes in the hippocampus and neurological and cognitive dysfunction caused by epilepsy. |
2022-05-09 |
2023-08-13 |
rat |
| Sebastian Dohm-Hansen, Francisco Donoso, Paul J Lucassen, Gerard Clarke, Yvonne M Nola. The gut microbiome and adult hippocampal neurogenesis: A new focal point for epilepsy? Neurobiology of disease. 2022-05-08. PMID:35526743. |
the gut microbiome and adult hippocampal neurogenesis: a new focal point for epilepsy? |
2022-05-08 |
2023-08-13 |
human |
| Artur Vetkas, Anton Fomenko, Jürgen Germann, Can Sarica, Christian Iorio-Morin, Nardin Samuel, Kazuaki Yamamoto, Vanessa Milano, Cletus Cheyuo, Ajmal Zemmar, Gavin Elias, Alexandre Boutet, Aaron Loh, Brendan Santyr, Dave Gwun, Jordy Tasserie, Suneil K Kalia, Andres M Lozan. Response: Letter to the Editor: Deep brain stimulation targets in epilepsy: Systematic review and meta-analysis of anterior and centromedian thalamic nuclei and hippocampus. Epilepsia. 2022-05-06. PMID:35514031. |
response: letter to the editor: deep brain stimulation targets in epilepsy: systematic review and meta-analysis of anterior and centromedian thalamic nuclei and hippocampus. |
2022-05-06 |
2023-08-13 |
Not clear |
| Seyyedeh Somayyeh Moshir Estekhareh, Sajjad Saghebdoust, Reza Zare, Mohsen Aghaee Hakak, Bahram Ali Ghanbari Hashemabad. Memory and executive functioning outcomes of selective amygdalohippocampectomy in patients with hippocampal sclerosis: A preliminary study in a developing country. Surgical neurology international. vol 13. 2022-05-05. PMID:35509560. |
selective amygdalohippocampectomy (sa) is an effective treatment for drug-resistant cases of epilepsy due to hippocampal sclerosis (hs). |
2022-05-05 |
2023-08-13 |
Not clear |
| Zhisen J Urgolites, John T Wixted, Stephen D Goldinger, Megan H Papesh, David M Treiman, Larry R Squire, Peter N Steinmet. Two kinds of memory signals in neurons of the human hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 19. 2022-05-05. PMID:35512097. |
in epilepsy patients, we detected single-unit activity reflecting episodic memory only in the hippocampus. |
2022-05-05 |
2023-08-13 |
human |
| Yingbei Qi, Heming Cheng, Qiuwen Lou, Xia Wang, Nanxi Lai, Chenshu Gao, Shuangshuang Wu, Cenglin Xu, Yeping Ruan, Zhong Chen, Yi Wan. Paradoxical effects of posterior intralaminar thalamic calretinin neurons on hippocampal seizure via distinct downstream circuits. iScience. vol 25. issue 5. 2022-05-02. PMID:35494226. |
these results indicated that cr neurons in the pil play separate roles in hippocampal seizures via distinct downstream circuits, which complements the pathogenic mechanisms of epilepsy and provides new insight for the precise medicine of epilepsy. |
2022-05-02 |
2023-08-13 |
Not clear |
| Leen M Al-Kraimeen, Obada Ababneh, Ahmed Yassi. Letter to the Editor: "Deep brain stimulation targets in epilepsy: Systematic review and meta-analysis of anterior and centromedian thalamic nuclei and hippocampus". Epilepsia. 2022-04-29. PMID:35485951. |
letter to the editor: "deep brain stimulation targets in epilepsy: systematic review and meta-analysis of anterior and centromedian thalamic nuclei and hippocampus". |
2022-04-29 |
2023-08-13 |
Not clear |
| Smriti Patodia, Alyma Somani, Joan Liu, Alice Cattaneo, Beatrice Paradiso, Maria Garcia, Muhammad Othman, Beate Diehl, Orrin Devinsky, James D Mills, Jackie Foong, Maria Tho. Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP. Brain pathology (Zurich, Switzerland). 2022-04-28. PMID:35478467. |
higher sert in hippocampal subfields in tle/hs cases with sudep risk factors and higher amygdala sert in post-mortem sudep cases than epilepsy controls supports a role for altered serotonergic networks involving limbic regions in sudep. |
2022-04-28 |
2023-08-13 |
Not clear |
| Sanya Rastogi, Kimford J Meador, William B Barr, Orrin Devinsky, Beth A Leeman-Markowsk. Remote Memory in Epilepsy: Assessment, Impairment, and Implications Regarding Hippocampal Function. Frontiers in neurology. vol 13. 2022-04-25. PMID:35463127. |
remote memory in epilepsy: assessment, impairment, and implications regarding hippocampal function. |
2022-04-25 |
2023-08-13 |
Not clear |