| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji-Eun Kim, Hana Park, Tae-Cheon Kan. Peroxiredoxin 6 Regulates Glutathione Peroxidase 1-Medited Glutamine Synthase Preservation in the Hippocampus of Chronic Epilepsy Rats. Antioxidants (Basel, Switzerland). vol 12. issue 1. 2023-01-21. PMID:36671018. |
peroxiredoxin 6 regulates glutathione peroxidase 1-medited glutamine synthase preservation in the hippocampus of chronic epilepsy rats. |
2023-01-21 |
2023-08-14 |
rat |
| Namgue Hong, Hee Jung Kim, Keunsoo Kang, Ji On Park, Seyoung Mun, Hyung-Gun Kim, Bong Hui Kang, Phil-Sang Chung, Min Young Lee, Jin-Chul Ah. Photobiomodulation improves the synapses and cognitive function and ameliorates epileptic seizure by inhibiting downregulation of Nlgn3. Cell & bioscience. vol 13. issue 1. 2023-01-12. PMID:36635704. |
we investigated whether tpbm exerts neuroprotective effects on hippocampal neurons in epilepsy mouse model by regulating synapse and synapse-related genes. |
2023-01-12 |
2023-08-14 |
mouse |
| Anatoly Buchin, Rebecca de Frates, Anirban Nandi, Rusty Mann, Peter Chong, Lindsay Ng, Jeremy Miller, Rebecca Hodge, Brian Kalmbach, Soumita Bose, Ueli Rutishauser, Stephen McConoughey, Ed Lein, Jim Berg, Staci Sorensen, Ryder Gwinn, Christof Koch, Jonathan Ting, Costas A Anastassio. Multi-modal characterization and simulation of human epileptic circuitry. Cell reports. vol 41. issue 13. 2022-12-28. PMID:36577383. |
here, we show that hippocampal granule cells change with disease progression as measured in living, resected hippocampal tissue excised from patients with epilepsy. |
2022-12-28 |
2023-08-14 |
human |
| Ekram Mohammadi, Farnaz Nikbakht, Somayeh Vazifekhah, Javad Fahanik Babae, Mohamad Taghi Jogatae. Evaluation the cognition-improvement effects of N-acetyl cysteine in experimental temporal lobe epilepsy in rat. Behavioural brain research. 2022-12-23. PMID:36563904. |
histological analysis showed that nac significantly increased the number of intact neurons in ca3 and hilar areas of the hippocampus following the induction of epilepsy. |
2022-12-23 |
2023-08-14 |
rat |
| Laura Rossini, Dalia De Santis, Erica Cecchini, Cinzia Cagnoli, Emanuela Maderna, Daniele Cartelli, Bryan Paul Morgan, Megan Torvell, Roberto Spreafico, Roberta di Giacomo, Laura Tassi, Marco de Curtis, Rita Garbell. Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation. Brain pathology (Zurich, Switzerland). 2022-12-23. PMID:36564349. |
neocortical tissues were collected from 20 subjects, mainly adults with a mean age at surgery of 31 years, admitted to epilepsy surgery with a neuropathological diagnosis of: cryptogenic, temporal lobe epilepsy with hippocampal sclerosis, and type iia/b fcd. |
2022-12-23 |
2023-08-14 |
human |
| Ellen J Bubrick, Nathan J McDannold, Phillip J Whit. Low Intensity Focused Ultrasound for Epilepsy- A New Approach to Neuromodulation. Epilepsy currents. vol 22. issue 3. 2022-12-07. PMID:36474831. |
resection after sonication to the antero-mesial lobe showed no pathologic changes in epilepsy patients, and this is currently being trialed in serial treatments to the hippocampus in dre. |
2022-12-07 |
2023-08-14 |
Not clear |
| Gianluca Lopez, Karam Han, Shino D Magaki, Sophie X Song, Noriko Salamon, Kanwarpal S Kahlon, Inna Keselman, Ausaf A Bari, Harry V Vinter. Low-grade B-cell lymphoma of the central nervous system with plasmacytic differentiation and amyloid deposition. Neuropathology : official journal of the Japanese Society of Neuropathology. 2022-12-01. PMID:36451532. |
a 65-year-old woman with a resolved history of epilepsy due to a motor vehicle accident and hippocampal sclerosis presented with recurrent de novo seizures. |
2022-12-01 |
2023-08-14 |
Not clear |
| Xiao-Xue Xu, Rui-Xue Shi, Yu Fu, Jia-Lu Wang, Xin Tong, Shi-Qi Zhang, Na Wang, Mei-Xuan Li, Yu Tong, Wei Wang, Miao He, Bing-Yang Liu, Gui-Lan Chen, Feng Gu. Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy. Neural regeneration research. vol 18. issue 6. 2022-12-01. PMID:36453412. |
in this study, we performed rna sequencing, functional enrichment analysis, and weighted gene coexpression network analysis of the hippocampus of tremor rats, a rat model of genetic epilepsy. |
2022-12-01 |
2023-08-14 |
rat |
| Nicola Masala, Martin Pofahl, André N Haubrich, Khondker Ushna Sameen Islam, Negar Nikbakht, Maryam Pasdarnavab, Kirsten Bohmbach, Kunihiko Araki, Fateme Kamali, Christian Henneberger, Kurtulus Golcuk, Laura A Ewell, Sandra Blaess, Tony Kelly, Heinz Bec. Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy. Brain : a journal of neurology. 2022-11-30. PMID:36448426. |
two-photon glutamate uncaging experiments revealed a marked increase in the fraction of hippocampal 1st order ca1 pyramidal cell dendrites capable of generating dendritic spikes in the kainate model of chronic epilepsy. |
2022-11-30 |
2023-08-14 |
mouse |
| Ana Gonzalez-Ramos, Kerstin Laurin, Fredrik Berglind, Marco Ledri, Merab Kokaia, My Andersso. Transplantation of Human Stem Cell-Derived GABAergic Neurons into the Early Postnatal Mouse Hippocampus to Mitigate Neurodevelopmental Disorders. Journal of visualized experiments : JoVE. issue 189. 2022-11-28. PMID:36440838. |
the transplanted neurons disperse in the ipsi- and contralateral hippocampus of a mouse model of cortical dysplasia-focal epilepsy syndrome and survive for up to 9 months after transplantation. |
2022-11-28 |
2023-08-14 |
mouse |
| Evgenia Sitnikova, Dmitrii Perevozniuk, Elizaveta Rutskova, Shukhrat Uzakov, Viktor A Korshuno. Reduction of Hippocampal High-Frequency Activity in Wag/Rij Rats with a Genetic Predisposition to Absence Epilepsy. Diagnostics (Basel, Switzerland). vol 12. issue 11. 2022-11-26. PMID:36428857. |
in contrast, absence epilepsy and other idiopathic epilepsies are known to result from thalamo-cortical abnormalities, with the hippocampus involvement considered to be only indirect. |
2022-11-26 |
2023-08-14 |
rat |
| Expression of Concern: Down-regulated microRNA-183 mediates the Jak/Stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting Foxp1. Cell cycle (Georgetown, Tex.). 2022-11-25. PMID:36426649. |
expression of concern: down-regulated microrna-183 mediates the jak/stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting foxp1. |
2022-11-25 |
2023-08-14 |
rat |
| Antje Kilias, Susanne Tulke, Nicole Barheier, Patrick Ruther, Ute Häussle. Integration of the CA2 region in the hippocampal network during epileptogenesis. Hippocampus. 2022-11-24. PMID:36421040. |
furthermore, they show increased excitability in vitro in hippocampal slices obtained from human mtle specimens or animal epilepsy models. |
2022-11-24 |
2023-08-14 |
mouse |
| Macarena S Aloi, Samantha J Thompson, Nicholas Quartapella, Jeffrey L Noebel. Loss of functional System x-c uncouples aberrant postnatal neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO mice. Cell reports. vol 41. issue 8. 2022-11-23. PMID:36417872. |
mutations in kv1.1 (kcna1) voltage-gated potassium channels in humans and mice generate network hyperexcitability, enhancing aberrant postnatal neurogenesis in the dentate subgranular zone, resulting in epilepsy and hippocampal hypertrophy. |
2022-11-23 |
2023-08-14 |
mouse |
| Macarena S Aloi, Samantha J Thompson, Nicholas Quartapella, Jeffrey L Noebel. Loss of functional System x-c uncouples aberrant postnatal neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO mice. Cell reports. vol 41. issue 8. 2022-11-23. PMID:36417872. |
here, we find that the functional unit of sxc, xct (slc7a11), is upregulated in regions of kcna1 knockout (ko) hippocampus, suggesting a contribution to both hyperplasia and epilepsy. |
2022-11-23 |
2023-08-14 |
mouse |
| Yong-Ge Li, Shu Zhou, Yin-le Yao, Xiao-Ming Wei, Shi-Feng Zhan. [The effects of vagus nerve stimulation on hippocampal neuro-inflammatory and α7nAChR expression in rats with intractable epilepsy]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 38. issue 4. 2022-11-22. PMID:36414564. |
[the effects of vagus nerve stimulation on hippocampal neuro-inflammatory and α7nachr expression in rats with intractable epilepsy]. |
2022-11-22 |
2023-08-14 |
rat |
| Satya S Sahoo, Katja Kobow, Jianzhe Zhang, Jeffrey Buchhalter, Mojtaba Dayyani, Dipak P Upadhyaya, Katrina Prantzalos, Meenakshi Bhattacharjee, Ingmar Blumcke, Samuel Wiebe, Samden D Lhato. Ontology-based feature engineering in machine learning workflows for heterogeneous epilepsy patient records. Scientific reports. vol 12. issue 1. 2022-11-13. PMID:36371527. |
this cohort included 312 patients who underwent epilepsy surgery and were labeled with one or more diagnoses, including dual pathology, hippocampal sclerosis, malformation of cortical dysplasia, tumor, encephalitis, and gliosis. |
2022-11-13 |
2023-08-14 |
Not clear |
| Mariana de Souza Aranha Garcia-Gomes, Pedro Kenzo Yamamoto, Silvia Maria Gomes Massironi, Orfa Yineth Galvis-Alonso, Jorge Mejia, Dennis Albert Zanatto, Sandra Regina Alexandre-Ribeiro, Susan Ienne, Claudia Madalena Cabrera Mor. Alteration of hippocampal Egr3, GABA A receptors, Il-1β, Il6 and Ccl3 expression in audiogenic tremor mice after seizure. Epilepsy & behavior : E&B. vol 137. issue Pt A. 2022-11-10. PMID:36356419. |
in conclusion, overexpression of ccl3 in the hippocampus of naive tremor mice, followed by downregulation soon after seizure in stimulated tremor mice, could be involved in changes in the blood-brain barrier (bbb) permeability in epilepsy. |
2022-11-10 |
2023-08-14 |
mouse |
| Daisuke Hasegawa, Shinichi Kanazono, James K Chambers, Kazuyuki Uchid. Neurosurgery in feline epilepsy, including clinicopathology of feline epilepsy syndromes. Veterinary journal (London, England : 1997). 2022-11-08. PMID:36347391. |
furthermore, approximately 50% of cats with epileptic seizures are diagnosed with structural epilepsy with or without hippocampal abnormality and may respond to surgical intervention. |
2022-11-08 |
2023-08-14 |
Not clear |
| Lin Guo, Tianyu Gao, Xiaoxia Jia, Ce Gao, Hao Tian, Yaqin Wei, Wenchun Lu, Zhidong Liu, Yun Wan. SKF83959 Attenuates Memory Impairment and Depressive-like Behavior during the Latent Period of Epilepsy via Allosteric Activation of the Sigma-1 Receptor. ACS chemical neuroscience. 2022-11-04. PMID:36331871. |
we found that skf83959 ameliorated memory impairment and depressive-like mood, alleviated the neuron damage and the formation of gliosis in hippocampus, suppressed the rise of pro-inflammatory cytokines, including tumor necrosis factor-α and interleukin-1β, and induced nitric oxide synthase in the latent period of epilepsy. |
2022-11-04 |
2023-08-14 |
mouse |