| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sanya Rastogi, Kimford J Meador, William B Barr, Orrin Devinsky, Beth A Leeman-Markowsk. Remote Memory in Epilepsy: Assessment, Impairment, and Implications Regarding Hippocampal Function. Frontiers in neurology. vol 13. 2022-04-25. PMID:35463127. |
this review of remote memory focuses on evidence for its underlying neurobiology, theoretical implications for hippocampal function, and methodological difficulties that complicate testing in epilepsy patients. |
2022-04-25 |
2023-08-13 |
Not clear |
| Dulcie Lai, Meethila Gade, Edward Yang, Hyun Yong Koh, Jinfeng Lu, Nicole M Walley, Anne F Buckley, Tristan T Sands, Cigdem I Akman, Mohamad A Mikati, Guy M McKhann, James E Goldman, Peter Canoll, Allyson L Alexander, Kristen L Park, Gretchen K Von Allmen, Olga Rodziyevska, Meenakshi B Bhattacharjee, Hart G W Lidov, Hannes Vogel, Gerald A Grant, Brenda E Porter, Annapurna H Poduri, Peter B Crino, Erin L Heinze. Somatic variants in diverse genes leads to a spectrum of focal cortical malformations. Brain : a journal of neurology. 2022-04-20. PMID:35441233. |
we also identified a somatic loss-of-function variant in the known epilepsy gene, pcdh19, present in a small number of alleles in the dysplastic tissue from a female patient with focal cortical dysplasia iiia with hippocampal sclerosis. |
2022-04-20 |
2023-08-13 |
Not clear |
| Noemi S Araújo, Selvin Z Reyes-Garcia, João A F Brogin, Douglas D Bueno, Esper A Cavalheiro, Carla A Scorza, Jean Fabe. Chaotic and stochastic dynamics of epileptiform-like activities in sclerotic hippocampus resected from patients with pharmacoresistant epilepsy. PLoS computational biology. vol 18. issue 4. 2022-04-13. PMID:35417449. |
chaotic and stochastic dynamics of epileptiform-like activities in sclerotic hippocampus resected from patients with pharmacoresistant epilepsy. |
2022-04-13 |
2023-08-13 |
Not clear |
| Yasushi Iimura, Mika Nakazawa, Hiroharu Suzuki, Takumi Mitsuhashi, Tetsuya Ueda, Koichiro Sakamoto, Kazuki Nishioka, Kou Horikoshi, Hidenori Sugan. Surgery for intractable epilepsy after severe encephalopathy with reversible splenial lesion and new onset hippocampal lesion associated with parechovirus. Brain & development. 2022-04-08. PMID:35393130. |
surgery for intractable epilepsy after severe encephalopathy with reversible splenial lesion and new onset hippocampal lesion associated with parechovirus. |
2022-04-08 |
2023-08-13 |
Not clear |
| Aswathy Ammothumkandy, Kristine Ravina, Victoria Wolseley, Alexandria N Tartt, Pen-Ning Yu, Luis Corona, Naibo Zhang, George Nune, Laura Kalayjian, J John Mann, Gorazd B Rosoklija, Victoria Arango, Andrew J Dwork, Brian Lee, J A D Smith, Dong Song, Theodore W Berger, Christianne Heck, Robert H Chow, Maura Boldrini, Charles Y Liu, Jonathan J Russin, Michael A Bonaguid. Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. Nature neuroscience. 2022-04-06. PMID:35383330. |
in the hippocampus, aberrant neurogenesis plays a critical role in the initiation and progression of epilepsy in rodent models, but it is unknown whether this also holds true in humans. |
2022-04-06 |
2023-08-13 |
human |
| Dorottya Cserpan, Antonio Gennari, Luca Gaito, Santo Pietro Lo Biundo, Ruth Tuura, Johannes Sarnthein, Georgia Ramantan. Scalp HFO rates are higher for larger lesions. Epilepsia open. 2022-03-31. PMID:35357778. |
we analyzed scalp eeg from 13 children and adolescents with focal epilepsy associated with focal cortical dysplasia (fcd), low-grade tumors, or hippocampal sclerosis. |
2022-03-31 |
2023-08-13 |
Not clear |
| Xiang Li, Qing Wang, Dian-Wen Zhang, Di Wu, Si-Wei Zhang, Zheng-Ren Wei, Xia Chen, Wei L. Hippocampus RNA Sequencing of Pentylenetetrazole-Kindled Rats and Upon Treatment of Novel Chemical Q808. Frontiers in pharmacology. vol 13. 2022-03-29. PMID:35345815. |
the expression of genes altered in epilepsy remains incomplete, particularly in the hippocampus, which exhibits exquisite vulnerability to epilepsy. |
2022-03-29 |
2023-08-13 |
rat |
| Bo-Yong Park, Sara Larivière, Raul Rodríguez-Cruces, Jessica Royer, Shahin Tavakol, Yezhou Wang, Lorenzo Caciagli, Maria Eugenia Caligiuri, Antonio Gambardella, Luis Concha, Simon S Keller, Fernando Cendes, Marina K M Alvim, Clarissa Yasuda, Leonardo Bonilha, Ezequiel Gleichgerrcht, Niels K Focke, Barbara A K Kreilkamp, Martin Domin, Felix von Podewils, Soenke Langner, Christian Rummel, Michael Rebsamen, Roland Wiest, Pascal Martin, Raviteja Kotikalapudi, Benjamin Bender, Terence J O'Brien, Meng Law, Benjamin Sinclair, Lucy Vivash, Patrick Kwan, Patricia M Desmond, Charles B Malpas, Elaine Lui, Saud Alhusaini, Colin P Doherty, Gianpiero L Cavalleri, Norman Delanty, Reetta Kälviäinen, Graeme D Jackson, Magdalena Kowalczyk, Mario Mascalchi, Mira Semmelroch, Rhys H Thomas, Hamid Soltanian-Zadeh, Esmaeil Davoodi-Bojd, Junsong Zhang, Matteo Lenge, Renzo Guerrini, Emanuele Bartolini, Khalid Hamandi, Sonya Foley, Bernd Weber, Chantal Depondt, Julie Absil, Sarah J A Carr, Eugenio Abela, Mark P Richardson, Orrin Devinsky, Mariasavina Severino, Pasquale Striano, Costanza Parodi, Domenico Tortora, Sean N Hatton, Sjoerd B Vos, John S Duncan, Marian Galovic, Christopher D Whelan, Núria Bargalló, Jose Pariente, Estefania Conde-Blanco, Anna Elisabetta Vaudano, Manuela Tondelli, Stefano Meletti, Xiang-Zhen Kong, Clyde Francks, Simon E Fisher, Benoit Caldairou, Mina Ryten, Angelo Labate, Sanjay M Sisodiya, Paul M Thompson, Carrie R McDonald, Andrea Bernasconi, Neda Bernasconi, Boris C Bernhard. Topographic divergence of atypical cortical asymmetry and atrophy patterns in temporal lobe epilepsy. Brain : a journal of neurology. 2022-03-25. PMID:35333312. |
temporal lobe epilepsy, a common drug-resistant epilepsy in adults, is primarily a limbic network disorder associated with predominant unilateral hippocampal pathology. |
2022-03-25 |
2023-08-13 |
human |
| Arife Çimen Atalar, Betül Bayka. Different Prognostic Patterns in Epilepsies and Considerations About the Denotations of Atypical Patterns. Noro psikiyatri arsivi. vol 59. issue 1. 2022-03-23. PMID:35317501. |
apart from these basic course patterns, there are some patients with an "atypical prognosis" such as drug-resistant juvenile myoclonic epilepsy (jme), benign hippocampal sclerosis-related mesial temporal lobe epilepsy (hs-mtle), and severe childhood epilepsy with centro-temporal spikes (cests), in which the pathophysiological mechanisms underlying these patterns have not been clarified despite the suggestions of various hypotheses. |
2022-03-23 |
2023-08-13 |
Not clear |
| Mahsa Tashakori-Miyanroudi, Samira Ramazi, Paria Hashemi, Morteza Nazari-Serenjeh, Tourandokht Baluchnejadmojarad, Mehrdad Roghan. Acetyl-L-Carnitine Exerts Neuroprotective and Anticonvulsant Effect in Kainate Murine Model of Temporal Lobe Epilepsy. Journal of molecular neuroscience : MN. 2022-03-23. PMID:35320462. |
the most well-known type of focal epilepsy that is resistant to existing treatments is temporal lobe epilepsy (tle), with seizure foci in various structures including temporal lobe, hippocampus, amygdala, entorhinal cortex, and subcortex. |
2022-03-23 |
2023-08-13 |
rat |
| Lianlian Wu, Ying Qin, Honghua Yuan, Yuhua Zhu, Ankang H. Anti-inflammatory and neuroprotective effects of insulin-like growth factor-1 overexpression in pentylenetetrazole (PTZ)-induced mouse model of chronic epilepsy. Brain research. 2022-03-14. PMID:35283097. |
moreover, we identified the evident increase in brdu-positive and dcx-positive cell populations in dentate gyrus (dg) in igf-1 transgenic mice, versus the w-t mice, indicative of the role of igf-1 overexpression in promoting long-term hippocampal neurogenesis in the chronic phase of epilepsy. |
2022-03-14 |
2023-08-13 |
mouse |
| Ying Zhang, Chi X. Effects of exosomes on adult hippocampal neurogenesis and neuropsychiatric disorders. Molecular biology reports. 2022-03-09. PMID:35262819. |
this review briefly introduces the synthesis and secretion mechanism of exosomes, and discuss the relationship between exosomes and hippocampal neurogenesis, and their roles in regulating depression, epilepsy and schizophrenia. |
2022-03-09 |
2023-08-13 |
Not clear |
| J Granna, E B Pitt, M E McKay, T J Ball, J S Neimat, D J Englot, R P Naftel, E J Barth, R J Webste. Targeting Epilepsy Through the Foremen Ovale: How Many Helical Needles are Needed? Annals of biomedical engineering. 2022-03-04. PMID:35244812. |
laser ablation of the hippocampus offers medically refractory epilepsy patients an alternative to invasive surgeries. |
2022-03-04 |
2023-08-13 |
Not clear |
| Chenmin He, Lingqi Ye, Cong Chen, Lingli Hu, Bo Jin, Yao Ding, Hong Li, Meiping Ding, Shan Wang, Shuang Wan. Hippocampal Malrotation Could Be Less Significant in Epilepsy Caused by Focal Cortical Dysplasia Type I and Type II. Frontiers in neurology. vol 13. 2022-03-03. PMID:35237224. |
hippocampal malrotation could be less significant in epilepsy caused by focal cortical dysplasia type i and type ii. |
2022-03-03 |
2023-08-13 |
Not clear |
| Chenmin He, Lingqi Ye, Cong Chen, Lingli Hu, Bo Jin, Yao Ding, Hong Li, Meiping Ding, Shan Wang, Shuang Wan. Hippocampal Malrotation Could Be Less Significant in Epilepsy Caused by Focal Cortical Dysplasia Type I and Type II. Frontiers in neurology. vol 13. 2022-03-03. PMID:35237224. |
debates over the relationship between hippocampal malrotation (himal) and epilepsy continue without consensus. |
2022-03-03 |
2023-08-13 |
Not clear |
| Cooper Penner, Juri Minxha, Nand Chandravadia, Adam N Mamelak, Ueli Rutishause. Properties and hemispheric differences of theta oscillations in the human hippocampus. Hippocampus. 2022-03-01. PMID:35231153. |
we recorded single-neuron and local field potentials from the human hippocampus in epilepsy patients implanted with depth electrodes. |
2022-03-01 |
2023-08-13 |
human |
| Willian Lazarini-Lopes, Gleice Kelli Silva-Cardoso, Christie Ramos Andrade Leite-Panissi, Norberto Garcia-Cairasc. Increased TRPV1 Channels and FosB Protein Expression Are Associated with Chronic Epileptic Seizures and Anxiogenic-like Behaviors in a Preclinical Model of Temporal Lobe Epilepsy. Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203625. |
chronic seizures increased anxiety-like behaviors and trpv1 and fosb expression in limbic and brainstem structures involved with epilepsy and anxiety comorbidity, such as the hippocampus, superior colliculus, and periaqueductal gray matter. |
2022-02-25 |
2023-08-13 |
rat |
| Alexandre Magno da Nobrega Marinho, Bruno Lobão-Soares, Hugo Alexandre Sousa Targino, Yago José Fernandes Vasconcellos, Ricardo Guarnieri, Carlos Gilberto Carlott. Decreased hippocampal serotonin 5HT Epilepsy & behavior : E&B. vol 129. 2022-02-21. PMID:35189481. |
decreased hippocampal serotonin 5ht mesial temporal lobe epilepsy related to hippocampal sclerosis (mtle-hs) is a surgically remediable epilepsy with a relatively high prevalence and psychiatric comorbidities. |
2022-02-21 |
2023-08-13 |
Not clear |
| Corwin R Butler, Gary L Westbrook, Eric Schnel. Adaptive mossy cell circuit plasticity after status epilepticus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-02-19. PMID:35181595. |
substantial mossy cell loss accompanies hippocampal circuit changes in epilepsy. |
2022-02-19 |
2023-08-13 |
mouse |
| M Morningstar, C Grannis, W I Mattson, E E Nelso. Functional patterns of neural activation during vocal emotion recognition in youth with and without refractory epilepsy. NeuroImage. Clinical. vol 34. 2022-02-19. PMID:35182929. |
activation to vocal emotional expressions in regions of the mentalizing and/or default mode network (e.g., right temporo-parietal junction, right hippocampus, right medial prefrontal cortex, among others) differentiated youth with and without epilepsy. |
2022-02-19 |
2023-08-13 |
Not clear |