| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| István Mihály, Tímea Molnár, Ádám-József Berki, Réka-Barbara Bod, Károly Orbán-Kis, Zsolt Gáll, Tibor Szilágy. Short-Term Amygdala Low-Frequency Stimulation Does not Influence Hippocampal Interneuron Changes Observed in the Pilocarpine Model of Epilepsy. Cells. vol 10. issue 3. 2021-11-19. PMID:33804543. |
short-term amygdala low-frequency stimulation does not influence hippocampal interneuron changes observed in the pilocarpine model of epilepsy. |
2021-11-19 |
2023-08-13 |
rat |
| István Mihály, Tímea Molnár, Ádám-József Berki, Réka-Barbara Bod, Károly Orbán-Kis, Zsolt Gáll, Tibor Szilágy. Short-Term Amygdala Low-Frequency Stimulation Does not Influence Hippocampal Interneuron Changes Observed in the Pilocarpine Model of Epilepsy. Cells. vol 10. issue 3. 2021-11-19. PMID:33804543. |
we aimed to depict the effect of amygdala dbs on the density of the most common interneuron types in the ca1 hippocampal subfield in the lithium-pilocarpine model of epilepsy. |
2021-11-19 |
2023-08-13 |
rat |
| Rick Hgj van Lanen, Stan Melchers, Govert Hoogland, Olaf Emg Schijns, Marc Amj van Zandvoort, Roel Hl Haeren, Kim Rijker. Microvascular changes associated with epilepsy: A narrative review. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 41. issue 10. 2021-11-19. PMID:33866850. |
anatomical studies show increased microvascular density in the hippocampus, amygdala, and neocortex accompanied by bbb leakage in various rodent epilepsy models. |
2021-11-19 |
2023-08-13 |
human |
| Du Xiao, Jingdan Lv, Zhigang Zheng, Yi Liu, Yonggen Zhang, Cuizhu Luo, Liu Qi, Bing Qin, Chao Li. Mechanisms of microRNA‑142 in mitochondrial autophagy and hippocampal damage in a rat model of epilepsy. International journal of molecular medicine. vol 47. issue 6. 2021-11-18. PMID:33846769. |
mechanisms of microrna‑142 in mitochondrial autophagy and hippocampal damage in a rat model of epilepsy. |
2021-11-18 |
2023-08-13 |
human |
| Raghava Jagadeesh Salaka, Kala P Nair, Kiruthiga Annamalai, Bettadapura N Srikumar, Bindu M Kutty, Byrathnahalli S Shankaranarayana Ra. Enriched environment ameliorates chronic temporal lobe epilepsy-induced behavioral hyperexcitability and restores synaptic plasticity in CA3-CA1 synapses in male Wistar rats. Journal of neuroscience research. vol 99. issue 6. 2021-11-17. PMID:33713475. |
chronic epilepsy resulted in behavioral hyperexcitability, decreased basal synaptic transmission, increased paired-pulse facilitation ratio, decreased hippocampal subfields volumes. |
2021-11-17 |
2023-08-13 |
rat |
| b' Ma\\xc5\\xa1a Kova\\xc4\\x8devi\\xc4\\x87, Dragoslav Soki\\xc4\\x87, Aleksandar J Risti\\xc4\\x87, Vladimir Ba\\xc5\\xa1\\xc4\\x8darevi\\xc4\\x87, Tijana \\xc4\\x90uki\\xc4\\x87, Aleksa Pejovi\\xc4\\x87, Nikola Vojvodi\\xc4\\x8. Focal to bilateral motor seizures in temporal lobe epilepsy during video-EEG monitoring: effects on surgical outcome. Acta neurologica Belgica. vol 121. issue 6. 2021-11-15. PMID:32813146.' |
we analyzed seizure recurrence after surgery with reference to: (i) occurrence of seizures after partial drug withdrawal during video-eeg monitoring (ftbms-m); (ii) history of secondarily generalized seizures during antiepileptic drug treatment prior to presurgical evaluation (ftbms-h) and (iii) other possible confounding factors (sex, age, epilepsy duration, side of surgery, presence of hippocampal sclerosis, and history of febrile seizures). |
2021-11-15 |
2023-08-13 |
Not clear |
| Borbála A Lőrincz, Agustina Anson, Stephan Handschuh, Alexander Tichy, Conor Rowan, Balázs B Lőrincz, Rita Garamvölgy. Hippocampal size did not differ between epileptic and non-epileptic dogs using volumetric and subjective methods. Acta veterinaria Hungarica. vol 69. issue 1. 2021-11-15. PMID:33835940. |
hippocampal changes in epilepsy may manifest as hippocampal atrophy/sclerosis. |
2021-11-15 |
2023-08-13 |
human |
| Yasmin Cruz Del Angel, James E Orfila, Paco S Herson, Amy Brooks-Kayal, Marco I Gonzále. Down-regulation of AMPA receptors and long-term potentiation during early epileptogenesis. Epilepsy & behavior : E&B. vol 124. 2021-11-15. PMID:34592633. |
in particular, alterations in hippocampal long-term potentiation (ltp), a well-accepted model of learning and memory, have been associated with altered cognition in epilepsy. |
2021-11-15 |
2023-08-13 |
Not clear |
| Y A Alshebib, Tomokatsu Hori, Taichi Kashiwag. HOP protein expression in the hippocampal dentate gyrus is acutely downregulated in a status epilepticus mouse model. IBRO neuroscience reports. vol 11. 2021-11-13. PMID:34766103. |
it is thought that prolonged seizures stimulate stem cells in the hippocampus and that epileptogenesis may arise from aberrant connections formed by newly born cells, while others have suggested that the acute neuroinflammation and gliosis often seen in epileptic hippocampi contribute to hyperexcitability and epilepsy development. |
2021-11-13 |
2023-08-13 |
mouse |
| b' Estefan\\xc3\\xada Conde-Blanco, Sa\\xc3\\xbcl Pascual-Diaz, Mar Carre\\xc3\\xb1o, Emma Mu\\xc3\\xb1oz-Moreno, Jos\\xc3\\xa9 Carlos Pariente, Teresa Boget, Isabel Manzanares, Antonio Donaire, Mar\\xc3\\xada Centeno, Francesc Graus, Nuria Bargall\\xc3\\xb. Volumetric and shape analysis of the hippocampus in temporal lobe epilepsy with GAD65 antibodies compared with non-immune epilepsy. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33986308.' |
volumetric and shape analysis of the hippocampus in temporal lobe epilepsy with gad65 antibodies compared with non-immune epilepsy. |
2021-11-08 |
2023-08-13 |
Not clear |
| Ping Zheng, He Bin, Wei Che. Inhibition of microRNA-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating BDNF. Cancer cell international. vol 19. issue 1. 2021-11-05. PMID:31049031. |
inhibition of microrna-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating bdnf. |
2021-11-05 |
2023-08-13 |
rat |
| Ping Zheng, He Bin, Wei Che. Inhibition of microRNA-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating BDNF. Cancer cell international. vol 19. issue 1. 2021-11-05. PMID:31049031. |
the aim of this study is to explore the effect of microrna-103a (mir-103a) on astrocytes activation and hippocampal neuron injury in epilepsy rats by targeting brain-derived neurotrophic factor (bdnf). |
2021-11-05 |
2023-08-13 |
rat |
| Daisuke Hasegawa, Rikako Asada, Yuji Hamamoto, Yoshihiko Yu, Takayuki Kuwabara, Shunta Mizoguchi, James K Chambers, Kazuyuki Uchid. Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy. Frontiers in veterinary science. vol 8. 2021-11-04. PMID:34355038. |
a 12-year-old neutered male domestic shorthair cat with presumed congenital cortical abnormalities (atrophy) in the right temporo-occipital cortex and hippocampus had been affected with epilepsy from 3 months of age. |
2021-11-04 |
2023-08-13 |
cat |
| Priscila Chiavellini, Martina Canatelli-Mallat, Marianne Lehmann, Rodolfo G Goya, Gustavo R More. Therapeutic potential of glial cell line-derived neurotrophic factor and cell reprogramming for hippocampal-related neurological disorders. Neural regeneration research. vol 17. issue 3. 2021-11-02. PMID:34380873. |
furthermore, dysregulation in the hippocampal function leads to epilepsy and mood disorders. |
2021-11-02 |
2023-08-13 |
Not clear |
| D I Pitskhelauri, E S Kudieva, A G Melikyan, P A Vlasov, M I Kamenetskaya, O S Zaitsev, A B Kozlova, N M Eliseeva, L V Shishkina, G V Danilov, I A Nagorskaya, A Z Sanikidze, T V Melnikova-Pitskhelauri, I N Pronin, A N Konovalo. [Surgical treatment of drug-resistant epilepsy following hippocampal sclerosis]. Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko. vol 85. issue 5. 2021-11-02. PMID:34714001. |
[surgical treatment of drug-resistant epilepsy following hippocampal sclerosis]. |
2021-11-02 |
2023-08-13 |
Not clear |
| Tih-Shih Lee, Alexander Y Li, Amedeo Rapuano, John Mantis, Tore Eid, Thomas N Seyfried, Nihal C de Laneroll. Gene expression in the epileptic (EL) mouse hippocampus. Neurobiology of disease. vol 147. 2021-11-01. PMID:33153970. |
the neuropathology of hippocampal seizure foci in human temporal lobe epilepsy (tle) and several animal models of epilepsy reveal extensive neuronal loss along with astrocyte and microglial activation. |
2021-11-01 |
2023-08-13 |
mouse |
| Hajime Miyata, Saeko Sudo, Haruka Kuwashige, Satoru Miyao, Hidetoshi Nakamoto, Yuichi Kubota, Yasuji Yoshid. Dual pathology in a patient with temporal lobe epilepsy associated with neocortical glial scar after brain abscess and end folium sclerosis/hippocampal sclerosis type 3. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 41. issue 1. 2021-10-28. PMID:33094499. |
the clinicopathological features in the present case indicate that hs developed secondarily in the context of neocortical epilepsy due to glial scar, suggesting a role of repetitive abnormal electrical input from neocortical epileptogenic lesions into the hippocampus finally via the perforant pathway in the pathogenesis of hs type 3. |
2021-10-28 |
2023-08-13 |
Not clear |
| Hajime Miyata, Saeko Sudo, Haruka Kuwashige, Satoru Miyao, Hidetoshi Nakamoto, Yuichi Kubota, Yasuji Yoshid. Dual pathology in a patient with temporal lobe epilepsy associated with neocortical glial scar after brain abscess and end folium sclerosis/hippocampal sclerosis type 3. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 41. issue 1. 2021-10-28. PMID:33094499. |
severe hippocampal atrophy on preoperative mri together with its silent electrocorticogram recording at initial epilepsy surgery may represent clinically pre-epileptogenic hs in a seizure-free "silent or latent period" before completion of hippocampal epileptogenesis to the extent that clinical epileptic seizures occur. |
2021-10-28 |
2023-08-13 |
Not clear |
| Meng Fu, Jie Tao, Dongdong Wang, Zhiping Zhang, Xiaoli Wang, Yonghua Ji, Zhiping L. Downregulation of MicroRNA-34c-5p facilitated neuroinflammation in drug-resistant epilepsy. Brain research. vol 1749. 2021-10-27. PMID:32950487. |
aggravated hippocampal neuron loss was demonstrated in rats with drug-resistant epilepsy. |
2021-10-27 |
2023-08-13 |
rat |
| Meng Fu, Jie Tao, Dongdong Wang, Zhiping Zhang, Xiaoli Wang, Yonghua Ji, Zhiping L. Downregulation of MicroRNA-34c-5p facilitated neuroinflammation in drug-resistant epilepsy. Brain research. vol 1749. 2021-10-27. PMID:32950487. |
our study highlights that decreased mir-34c-5p in drug-resistant epilepsy exacerbates neuroinflammation, which aggravates hippocampal neuron loss in epileptogenesis. |
2021-10-27 |
2023-08-13 |
rat |