| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yinbao Qi, Ruobing Qian, Li Jia, Xiaorui Fei, Dong Zhang, Yiming Zhang, Sen Jiang, Xianming F. Overexpressed microRNA-494 represses RIPK1 to attenuate hippocampal neuron injury in epilepsy rats by inactivating the NF-κB signaling pathway. Cell cycle (Georgetown, Tex.). vol 19. issue 11. 2021-08-26. PMID:32308116. |
overexpressed microrna-494 represses ripk1 to attenuate hippocampal neuron injury in epilepsy rats by inactivating the nf-κb signaling pathway. |
2021-08-26 |
2023-08-13 |
rat |
| Xiaona Wang, Yaodong Zhang, Weyland Cheng, Yinbo Gao, Shao L. Decreased excitatory drive onto hilar neuronal nitric oxide synthase expressing interneurons in chronic models of epilepsy. Brain research. vol 1764. 2021-08-25. PMID:33831408. |
in summary, we propose that impaired excitatory drive onto hippocampal nnos interneurons may be implicated in the development of refractory epilepsy. |
2021-08-25 |
2023-08-13 |
mouse |
| Huifang Cao, Lichao Zhang, Zhenzhen Qu, Shuang Tian, Zhiyong Wang, Yuhang Jiang, Qian Hou, Lijing Jia, Weiping Wan. The protective effect of hydroxylated fullerene pretreatment on pilocarpine-induced status epilepticus. Brain research. vol 1764. 2021-08-25. PMID:33831409. |
the expressions of these proteins in hfs pretreatment groups increased more significantly than those in the epilepsy (ep) group, which effectively reduced lipid peroxidation and apoptosis in the hippocampus. |
2021-08-25 |
2023-08-13 |
rat |
| Rodrigo Ribeiro Dos Santos, Túlio C Bernardino, Maria Carolina Machado da Silva, Antônio C P de Oliveira, Luciana E Drumond, Daniela V Rosa, André R Massensini, Márcio F D Moraes, Maria C Doretto, Marco A Romano-Silva, Helton J Rei. Neurochemical abnormalities in the hippocampus of male rats displaying audiogenic seizures, a genetic model of epilepsy. Neuroscience letters. vol 761. 2021-08-25. PMID:34293418. |
neurochemical abnormalities in the hippocampus of male rats displaying audiogenic seizures, a genetic model of epilepsy. |
2021-08-25 |
2023-08-13 |
rat |
| Emanuele Mocciaro, Auston Grant, Rinat O Esenaliev, Irene Y Petrov, Yuriy Petrov, Stacy L Sell, Nicole L Hausser, Jutatip Guptarak, Elizabeth Bishop, Margaret A Parsley, Ian J Bolding, Kathia M Johnson, Maxwell Lidstone, Donald S Prough, Maria-Adelaide Micc. Non-Invasive Transcranial Nano-Pulsed Laser Therapy Ameliorates Cognitive Function and Prevents Aberrant Migration of Neural Progenitor Cells in the Hippocampus of Rats Subjected to Traumatic Brain Injury. Journal of neurotrauma. vol 37. issue 8. 2021-08-18. PMID:31856661. |
while increased proliferation of nsc in the hippocampus is known to occur shortly after injury, reduced neuronal maturation and aberrant migration of progenitor cells in the hilus contribute to cognitive and neurological dysfunctions, including epilepsy. |
2021-08-18 |
2023-08-13 |
rat |
| Trevor A Steve, Justine Gargula, Ehsan Misaghi, Tomasz A Nowacki, Laura M Schmitt, B Matt Wheatley, Donald W Gros. Hippocampal subfield measurement and ILAE hippocampal sclerosis subtype classification with in vivo 4.7 tesla MRI. Epilepsy research. vol 161. 2021-08-18. PMID:32105992. |
however, hs subtypes currently can only be diagnosed by pathological analysis of hippocampal tissue resected during epilepsy surgery or at autopsy. |
2021-08-18 |
2023-08-13 |
Not clear |
| Trevor A Steve, Justine Gargula, Ehsan Misaghi, Tomasz A Nowacki, Laura M Schmitt, B Matt Wheatley, Donald W Gros. Hippocampal subfield measurement and ILAE hippocampal sclerosis subtype classification with in vivo 4.7 tesla MRI. Epilepsy research. vol 161. 2021-08-18. PMID:32105992. |
in this study, we aimed to: i) evaluate the reliability of our histology-derived segmentation protocol when applied to in vivo mri; and ii) characterize variability of hs subtypes along the hippocampal long axis in patients with epilepsy. |
2021-08-18 |
2023-08-13 |
Not clear |
| Mohammed Elsherif, Ahmed Esmae. Hippocampal atrophy and quantitative EEG markers in mild cognitive impairment in temporal lobe epilepsy versus extra-temporal lobe epilepsy. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2021-08-18. PMID:34406537. |
hippocampal atrophy and quantitative eeg markers in mild cognitive impairment in temporal lobe epilepsy versus extra-temporal lobe epilepsy. |
2021-08-18 |
2023-08-13 |
Not clear |
| Ke Xu, Xiongfei Wang, Yuguang Guan, Meng Zhao, Chongyang Tang, Jian Zhou, Feng Zhai, Mengyang Wang, Zejun Duan, Xueling Qi, Tianfu Li, Guoming Lua. Prognostic value of histopathologic pattern for long-term surgical outcomes of 198 patients with confirmed mesial temporal lobe epilepsy. Human pathology. vol 115. 2021-08-16. PMID:34119513. |
the main findings were as follows: 1) temporal neocortical gray matter heterotopia were more common in the no-hs group; 2) hs type 1 was associated with a longer duration of epilepsy; 3) history of meningitis was the independent predictor of hs type 1; 4) no-hs patients experienced worse postoperative seizure outcomes than those with hs type1 and type 2, whereas no difference in seizure outcomes was obtained between hs type 1 and type 2; 5) no-hs patients were at increased risk for verbal memory decline after left hippocampal resection. |
2021-08-16 |
2023-08-13 |
Not clear |
| Hao Wu, Yong Liu, Lishuo Liu, Qiang Meng, Changwang Du, Kuo Li, Shan Dong, Yong Zhang, Huanfa Li, Hua Zhan. Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34261484. |
we first investigated the levels of bmal1 and other clock proteins in the hippocampus of subjects with epilepsy to define the function of bmal1. |
2021-08-12 |
2023-08-13 |
human |
| Hsin-Hua Li, Pin-Jiun Lin, Wei-Han Wang, Li-Ho Tseng, Hsin Tung, Wen-Yuan Liu, Chih-Li Lin, Chiung-Hui Liu, Wen-Chieh Liao, Ching-Sui Hung, Ying-Jui H. Treatment effects of the combination of ceftriaxone and valproic acid on neuronal and behavioural functions in a rat model of epilepsy. Experimental physiology. vol 106. issue 8. 2021-07-30. PMID:34086374. |
ceftriaxone suppressed seizure and cognitive deficits and restored neuronal density and the number of newborn cells in the hippocampus in a rat model of epilepsy. |
2021-07-30 |
2023-08-13 |
rat |
| Ali A Asadi-Pooya, Luca Bartolin. Prevention and treatment of temporal lobe epilepsy: lessons from hepatitis B story! The International journal of neuroscience. vol 130. issue 11. 2021-07-29. PMID:32053411. |
temporal lobe epilepsy (tle) is the most common type of drug-resistant epilepsy and hippocampal sclerosis (hs) is the most common pathological substrate of tle. |
2021-07-29 |
2023-08-13 |
human |
| James Morgan, Mariana Alves, Giorgia Conte, Aida Menéndez-Méndez, Laura de Diego-Garcia, Gioacchino de Leo, Edward Beamer, Jonathon Smith, Annette Nicke, Tobias Enge. Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse. Neuroscience bulletin. vol 36. issue 11. 2021-07-28. PMID:32895896. |
while increased expression of p2x7 in the hippocampus and cortex following status epilepticus and during epilepsy has been repeatedly demonstrated, the cell type-specific expression of p2x7 and its expression in extra-hippocampal brain structures remains incompletely explored. |
2021-07-28 |
2023-08-13 |
mouse |
| James Morgan, Mariana Alves, Giorgia Conte, Aida Menéndez-Méndez, Laura de Diego-Garcia, Gioacchino de Leo, Edward Beamer, Jonathon Smith, Annette Nicke, Tobias Enge. Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse. Neuroscience bulletin. vol 36. issue 11. 2021-07-28. PMID:32895896. |
the results showed increased p2x7-egfp expression after status epilepticus induced by intra-amygdala kainic acid and during epilepsy in different brain regions including the hippocampus, cortex, striatum, thalamus and cerebellum, and this was most evident in microglia and oligodendrocytes. |
2021-07-28 |
2023-08-13 |
mouse |
| Fatma Ayhan, Ashwinikumar Kulkarni, Stefano Berto, Karthigayini Sivaprakasam, Connor Douglas, Bradley C Lega, Genevieve Konopk. Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans. Neuron. vol 109. issue 13. 2021-07-23. PMID:34051145. |
to understand the cellular and molecular diversity along the hippocampal long axis in human brain and define molecular signatures corresponding to functional domains, we performed single-nuclei rna sequencing on surgically resected human anterior and posterior hippocampus from epilepsy patients, identifying differentially expressed genes at cellular resolution. |
2021-07-23 |
2023-08-13 |
human |
| Shunsuke Takag. Exploring Ripple Waves in the Human Brain. Clinical EEG and neuroscience. 2021-07-21. PMID:34287087. |
in addition, spw-rs in the human hippocampus have been recorded from patients with epilepsy who may have p-ripples. |
2021-07-21 |
2023-08-13 |
human |
| Wei Pan, Xingyu Song, Qibo Hu, Yunfeng Zhan. miR-485 inhibits histone deacetylase HDAC5, HIF1α and PFKFB3 expression to alleviate epilepsy in cellular and rodent models. Aging. vol 13. issue 10. 2021-07-20. PMID:34021541. |
we established a cellular epilepsy model by exposing hippocampal neurons to magnesium and a rat model by treating icr mice with lithium chloride (127 mg/kg) and pilocarpine (30 mg/kg). |
2021-07-20 |
2023-08-13 |
mouse |
| Ozan Hasimoglu, Ozan Barut, Meliha Ozge Kapar, Omer Batu Hergunsel, Demet Kinay, Gunay Gul, Ayten Ceyhan Dirican, Bilge Bilgic, Bekir Tugc. Relation Between ILAE Hippocampal Sclerosis Classification and Clinical Findings in Temporal Lobe Epilepsy. Turkish neurosurgery. vol 31. issue 3. 2021-07-15. PMID:33759167. |
to investigate the relationship between clinical features and prognosis of the hippocampal sclerosis (hs) cases and international league against epilepsy (ilae) histopathology classification. |
2021-07-15 |
2023-08-13 |
Not clear |
| Natalia V Gulyaev. Stress-Associated Molecular and Cellular Hippocampal Mechanisms Common for Epilepsy and Comorbid Depressive Disorders. Biochemistry. Biokhimiia. vol 86. issue 6. 2021-07-15. PMID:34225588. |
stress-associated molecular and cellular hippocampal mechanisms common for epilepsy and comorbid depressive disorders. |
2021-07-15 |
2023-08-13 |
Not clear |
| Hongxin Wang, Guangyan Yao, Lei Li, Zhaoyin Ma, Jing Chen, Wen Che. LncRNA-UCA1 inhibits the astrocyte activation in the temporal lobe epilepsy via regulating the JAK/STAT signaling pathway. Journal of cellular biochemistry. vol 121. issue 10. 2021-07-12. PMID:31909503. |
furthermore, the immunofluorescence and western blot analysis revealed that the overexpression of uca1 inhibited ka-induced abnormal elevation of glast, astrocyte activation of the jak/stat signaling pathway, as well as hippocampus of epilepsy rats. |
2021-07-12 |
2023-08-13 |
rat |