Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Hongxuan Feng, Qian Gui, Guanhui Wu, Wei Zhu, Xiaofeng Dong, Mingqiang Shen, Xuetao Fu, Guomei Shi, Hailong Luo, Xiaoyan Yang, Shouru Xue, Qingzhang Chen. Long noncoding RNA Nespas inhibits apoptosis of epileptiform hippocampal neurons by inhibiting the PI3K/Akt/mTOR pathway. Experimental cell research. vol 398. issue 1. 2021-04-30. PMID:33212147. |
our findings revealed that nespas suppressed the apoptosis of epileptiform hippocampal neurons by inhibiting the pi3k/akt/mtor pathway via upregulation of psmd11 at a mir-615-3p dependent way, indicating that nespas may offer a new direction for the treatment of epilepsy. |
2021-04-30 |
2023-08-13 |
Not clear |
Jungong Jin, Xi Shen, Lu Tian, Guoyishi He, Ying Zhan. Pyrazolo[4,3-c]pyridine-4-one (PP-4-one) Exhibits Anti-Epileptogenic Effect in Rat Model of Traumatic Epilepsy by Mammalian Target of Rapamycin (mTOR) Signaling Pathway Downregulation. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-04-27. PMID:32687486. |
the data revealed markedly higher levels of p-mtor and p-p70s6k in rat hippocampal tissues after induction of traumatic epilepsy. |
2021-04-27 |
2023-08-13 |
rat |
Fang Chen, Hongjia Zheng, Wenyu Zhang, Jie Kang, Qiao Liu, Juan Pu, Ling Yan. circ_0003170 aggravates human hippocampal neuron injuries by regulating the miR-421/CCL2 axis in cells models of epilepsy. General physiology and biophysics. vol 40. issue 2. 2021-04-23. PMID:33880998. |
circ_0003170 aggravates human hippocampal neuron injuries by regulating the mir-421/ccl2 axis in cells models of epilepsy. |
2021-04-23 |
2023-08-13 |
human |
Fang Chen, Hongjia Zheng, Wenyu Zhang, Jie Kang, Qiao Liu, Juan Pu, Ling Yan. circ_0003170 aggravates human hippocampal neuron injuries by regulating the miR-421/CCL2 axis in cells models of epilepsy. General physiology and biophysics. vol 40. issue 2. 2021-04-23. PMID:33880998. |
epilepsy models were established in human hippocampal neurons treated by magnesium-free (mg2+-free) solution. |
2021-04-23 |
2023-08-13 |
human |
Laura Rossini, Dalia De Santis, Roberta Rosa Mauceri, Chiara Tesoriero, Marina Bentivoglio, Emanuela Maderna, Antonio Maiorana, Francesco Deleo, Marco de Curtis, Giovanni Tringali, Massimo Cossu, Gemma Tumminelli, Manuela Bramerio, Roberto Spreafico, Laura Tassi, Rita Garbell. Dendritic pathology, spine loss and synaptic reorganization in human cortex from epilepsy patients. Brain : a journal of neurology. vol 144. issue 1. 2021-04-20. PMID:33221837. |
alterations in dendritic morphology and spine loss mainly in hippocampal neurons have been reported both in epilepsy animal models and in human brain tissues from patients with epilepsy. |
2021-04-20 |
2023-08-13 |
human |
Despina Tsortouktzidis, Herbert Schulz, Motaz Hamed, Hartmut Vatter, Rainer Surges, Susanne Schoch, Thomas Sander, Albert J Becker, Karen M J van Lo. Gene expression analysis in epileptic hippocampi reveals a promoter haplotype conferring reduced aldehyde dehydrogenase 5a1 expression and responsiveness. Epilepsia. vol 62. issue 1. 2021-04-19. PMID:33319393. |
the present data suggest systematic analyses in human hippocampal tissue as a useful approach to unravel the impact of epilepsy candidate snps on associated gene expression. |
2021-04-19 |
2023-08-13 |
human |
Carlotta Mutti, Matteo Riccò, Yerma Bartolini, Giorgia Bernabè, Irene Trippi, Andrea Melpignano, Rosario Ciliento, Lucia Zinno, Irene Florindo, Enrico Sasso, Anna Odone, Liborio Parrino, Anna Elisabetta Vaudan. Incomplete hippocampal inversion and epilepsy: A systematic review and meta-analysis. Epilepsia. vol 62. issue 2. 2021-04-19. PMID:33325054. |
incomplete hippocampal inversion and epilepsy: a systematic review and meta-analysis. |
2021-04-19 |
2023-08-13 |
Not clear |
Carlotta Mutti, Matteo Riccò, Yerma Bartolini, Giorgia Bernabè, Irene Trippi, Andrea Melpignano, Rosario Ciliento, Lucia Zinno, Irene Florindo, Enrico Sasso, Anna Odone, Liborio Parrino, Anna Elisabetta Vaudan. Incomplete hippocampal inversion and epilepsy: A systematic review and meta-analysis. Epilepsia. vol 62. issue 2. 2021-04-19. PMID:33325054. |
incomplete hippocampal inversion (ihi) is a relatively frequent radiological finding at visual inspection in both epilepsy and healthy controls, but its clinical significance is unclear. |
2021-04-19 |
2023-08-13 |
Not clear |
Zhihao Guo, Baotian Zhao, Wenhan Hu, Chao Zhang, Xiu Wang, Yao Wang, Chang Liu, Jiajie Mo, Lin Sang, Yanshan Ma, Xiaoqiu Shao, Jianguo Zhang, Kai Zhan. Effective connectivity among the hippocampus, amygdala, and temporal neocortex in epilepsy patients: A cortico-cortical evoked potential study. Epilepsy & behavior : E&B. vol 115. 2021-04-19. PMID:33434884. |
effective connectivity among the hippocampus, amygdala, and temporal neocortex in epilepsy patients: a cortico-cortical evoked potential study. |
2021-04-19 |
2023-08-13 |
Not clear |
Ceren Günbey, Figen Söylemezoğlu, Burçak Bilginer, Kader Karlı Oğuz, Nejat Akalan, Meral Topçu, Güzide Turanlı, Dilek Yalnızoğl. International consensus classification of hippocampal sclerosis and etiologic diversity in children with temporal lobectomy. Epilepsy & behavior : E&B. vol 112. 2021-04-14. PMID:32882628. |
the distribution of hippocampal sclerosis (hs) subtypes, according to the classification of the international league against epilepsy (ilae), has been reported mainly in adult patients. |
2021-04-14 |
2023-08-13 |
Not clear |
Alexey A Kulikov, Nadezhda A Dorofeeva, Alexandra A Naumova, Eugenia L Harbachova, Margarita V Glazova, Elena V Chernigovskay. Impaired postnatal development of the hippocampus of Krushinsky-Molodkina rats genetically prone to audiogenic seizures. Epilepsy & behavior : E&B. vol 113. 2021-04-14. PMID:33161330. |
the hippocampus plays an important role in epilepsy progression even if it is not involved in seizure generalization. |
2021-04-14 |
2023-08-13 |
rat |
Alexey A Kulikov, Nadezhda A Dorofeeva, Alexandra A Naumova, Eugenia L Harbachova, Margarita V Glazova, Elena V Chernigovskay. Impaired postnatal development of the hippocampus of Krushinsky-Molodkina rats genetically prone to audiogenic seizures. Epilepsy & behavior : E&B. vol 113. 2021-04-14. PMID:33161330. |
here we analyzed postnatal development of the hippocampus of krushinsky-molodkina (km) rats, which are the animal model of reflex audiogenic epilepsy. |
2021-04-14 |
2023-08-13 |
rat |
Ahmet Sevki Taskıran, Ercan Ozdemir, Erkan Gumus, Mustafa Ergu. The effects of salmon calcitonin on epileptic seizures, epileptogenesis, and postseizure hippocampal neuronal damage in pentylenetetrazole-induced epilepsy model in rats. Epilepsy & behavior : E&B. vol 113. 2021-04-14. PMID:33220584. |
the effects of salmon calcitonin on epileptic seizures, epileptogenesis, and postseizure hippocampal neuronal damage in pentylenetetrazole-induced epilepsy model in rats. |
2021-04-14 |
2023-08-13 |
rat |
Ahmet Sevki Taskıran, Ercan Ozdemir, Erkan Gumus, Mustafa Ergu. The effects of salmon calcitonin on epileptic seizures, epileptogenesis, and postseizure hippocampal neuronal damage in pentylenetetrazole-induced epilepsy model in rats. Epilepsy & behavior : E&B. vol 113. 2021-04-14. PMID:33220584. |
this study aimed to investigate the effect of sct on epileptic seizures, epileptogenesis, and postseizure hippocampal neuronal damage in pentylenetetrazole (ptz)-induced epilepsy model in rats. |
2021-04-14 |
2023-08-13 |
rat |
Shihui Chen, Jian Zhang, Xiaolei Ruan, Kan Deng, Jianing Zhang, Dongfang Zou, Xiaoming He, Feng Li, Guo Bin, Hongwu Zeng, Bingsheng Huan. Voxel-based morphometry analysis and machine learning based classification in pediatric mesial temporal lobe epilepsy with hippocampal sclerosis. Brain imaging and behavior. vol 14. issue 5. 2021-04-13. PMID:31250266. |
mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) is a common type of pediatric epilepsy. |
2021-04-13 |
2023-08-13 |
human |
Massimo Cossu, Piergiorgio d'Orio, Carmen Barba, Sofia Asioli, Francesco Cardinale, Sara Casciato, Massimo Caulo, Gabriella Colicchio, Alessandro Consales, Alfredo D'Aniello, Alessandro De Benedictis, Luca De Palma, Giuseppe Didato, Giancarlo Di Gennaro, Roberta Di Giacomo, Vincenzo Esposito, Renzo Guerrini, Michele Nichelatti, Martina Revay, Michele Rizzi, Giampaolo Vatti, Flavio Villani, Nelia Zamponi, Laura Tassi, Carlo Efisio Marra. Focal Cortical Dysplasia IIIa in Hippocampal Sclerosis-Associated Epilepsy: Anatomo-Electro-Clinical Profile and Surgical Results From a Multicentric Retrospective Study. Neurosurgery. vol 88. issue 2. 2021-04-13. PMID:32860416. |
focal cortical dysplasia iiia in hippocampal sclerosis-associated epilepsy: anatomo-electro-clinical profile and surgical results from a multicentric retrospective study. |
2021-04-13 |
2023-08-13 |
Not clear |
Paula Agudelo Valencia, Nicole E C van Klink, Maryse A van 't Klooster, Willemiek J E M Zweiphenning, Banu Swampillai, Pieter van Eijsden, Tineke Gebbink, Martine J E van Zandvoort, Maeike Zijlman. Are HFOs in the Intra-operative ECoG Related to Hippocampal Sclerosis, Volume and IQ? Frontiers in neurology. vol 12. 2021-04-13. PMID:33841312. |
temporal lobe epilepsy (tle) is the most common form of refractory focal epilepsy and is often associated with hippocampal sclerosis (hs) and cognitive disturbances. |
2021-04-13 |
2023-08-13 |
Not clear |
Lisanne P W Canjels, Walter H Backes, Tamar M van Veenendaal, Marielle C G Vlooswijk, Paul A M Hofman, Albert P Aldenkamp, Rob P W Rouhl, Jacobus F A Janse. Volumetric and Functional Activity Lateralization in Healthy Subjects and Patients with Focal Epilepsy: Initial Findings in a 7T MRI Study. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 30. issue 5. 2021-04-06. PMID:32472965. |
we set out to assess 7t mri-derived volumetric and functional activity lateralization of the hippocampus, hippocampal subfields, temporal and frontal lobe in healthy subjects and mri-negative patients with focal epilepsy. |
2021-04-06 |
2023-08-13 |
human |
Haitao Zhu, Honghao Xu, Haiyan Ma, Lei Luo, Lu Yang, Fangqing Chen, Xuefeng Qu, Hongyi Liu, Rui Zhan. LncRNA CASC2 inhibits astrocytic activation and adenosine metabolism by regulating PTEN in pentylenetetrazol-induced epilepsy model. Journal of chemical neuroanatomy. vol 105. 2021-04-02. PMID:31958564. |
we adopted qrt-pcr on the hippocampus of rats following pentylenetetrazol (ptz)-stimulated epilepsy. |
2021-04-02 |
2023-08-13 |
rat |
Karina Pereira Gomes, Pedro Paulo Pereira Braga, Claudio Quintino de Lima, Poliana Peres Ghazale, Gustavo Rodrigues Pedrino, Elizabeth Pereira Mendes, Aline Priscila Pansani, Carlos Henrique Xavier, Carlos Henrique Castro, Diego Basile Colugnat. Antiepileptic effects of long-term intracerebroventricular infusion of angiotensin-(1-7) in an animal model of temporal lobe epilepsy. Clinical science (London, England : 1979). vol 134. issue 17. 2021-03-23. PMID:32803259. |
the hippocampal up-regulation of angiotensin type 1 receptor induced by tle was also attenuated by ang-(1-7), while the mas receptor (masr) was down-regulated compared with epilepsy. |
2021-03-23 |
2023-08-13 |
rat |