| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weixi Xiong, Lu Lu, Qin Chen, Yingfeng Xiao, Dongmei An, Josemir W Sander, Ming Zhang, Dong Zho. Reduction of Retinal Thickness Ipsilateral to Hippocampal Sclerosis in Epilepsy. Frontiers in neurology. vol 12. 2021-05-30. PMID:34046004. |
reduction of retinal thickness ipsilateral to hippocampal sclerosis in epilepsy. |
2021-05-30 |
2023-08-13 |
Not clear |
| Xinyan Dong, Xiaoxu Hao, Peng Xu, Miao Fan, Xuehui Wang, Xin Huang, Peifang Jiang, Linghui Zeng, Yicheng Xi. RNA sequencing analysis of cortex and hippocampus in a kainic acid rat model of temporal lobe epilepsy to identify mechanisms and therapeutic targets related to inflammation, immunity and cognition. International immunopharmacology. vol 87. 2021-05-27. PMID:32736192. |
here, a rat model of epilepsy was established by kainic acid (ka) administration gene transcriptome was explored in 4 signature phases in the hippocampus and cortex: acute damage (3 h), onset of epileptogenesis (3 d), spontaneous epilepsy (2 w) and cognitive impairment (9 w). |
2021-05-27 |
2023-08-13 |
rat |
| Ji-Eun Kim, Tae-Cheon Kan. CDDO-Me Attenuates Astroglial Autophagy via Nrf2-, ERK1/2-SP1- and Src-CK2-PTEN-PI3K/AKT-Mediated Signaling Pathways in the Hippocampus of Chronic Epilepsy Rats. Antioxidants (Basel, Switzerland). vol 10. issue 5. 2021-05-27. PMID:33922531. |
cddo-me attenuates astroglial autophagy via nrf2-, erk1/2-sp1- and src-ck2-pten-pi3k/akt-mediated signaling pathways in the hippocampus of chronic epilepsy rats. |
2021-05-27 |
2023-08-13 |
rat |
| Connor D Courtney, Catherine Christian-Hinma. Assessin' the Vexin' Connexin Between Severity of Epilepsy and Hippocampal Gliosis. Epilepsy currents. vol 20. issue 5. 2021-05-26. PMID:34025243. |
assessin' the vexin' connexin between severity of epilepsy and hippocampal gliosis. |
2021-05-26 |
2023-08-13 |
Not clear |
| Silvia Regina Bica Kohek, Maira Licia Foresti, Miriam Marcela Blanco, Clarissa Fantin Cavarsan, Clivandir Severino da Silva, Luiz E Mell. Anxious Profile Influences Behavioral and Immunohistological Findings in the Pilocarpine Model of Epilepsy. Frontiers in pharmacology. vol 12. 2021-05-26. PMID:34025410. |
in addition, brain structures such as the hippocampus and amygdala might have a critical relevance in both epilepsy and anxiety. |
2021-05-26 |
2023-08-13 |
Not clear |
| K J Debski, N Ceglia, A Ghestem, A I Ivanov, G E Brancati, S Bröer, A M Bot, J A Müller, S Schoch, A Becker, W Löscher, M Guye, P Sassone-Corsi, K Lukasiuk, P Baldi, C Bernar. The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy. Science advances. vol 6. issue 41. 2021-05-24. PMID:33036982. |
whether these oscillations occur in the healthy hippocampus and whether they are altered in epilepsy are not known. |
2021-05-24 |
2023-08-13 |
mouse |
| K J Debski, N Ceglia, A Ghestem, A I Ivanov, G E Brancati, S Bröer, A M Bot, J A Müller, S Schoch, A Becker, W Löscher, M Guye, P Sassone-Corsi, K Lukasiuk, P Baldi, C Bernar. The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy. Science advances. vol 6. issue 41. 2021-05-24. PMID:33036982. |
thus, the control hippocampus shows circadian molecular remapping, which is altered in epilepsy. |
2021-05-24 |
2023-08-13 |
mouse |
| K J Debski, N Ceglia, A Ghestem, A I Ivanov, G E Brancati, S Bröer, A M Bot, J A Müller, S Schoch, A Becker, W Löscher, M Guye, P Sassone-Corsi, K Lukasiuk, P Baldi, C Bernar. The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy. Science advances. vol 6. issue 41. 2021-05-24. PMID:33036982. |
we suggest that the hippocampus operates in a different functioning mode in epilepsy. |
2021-05-24 |
2023-08-13 |
mouse |
| Di Zuo, Feng Wang, Weifang Rong, Yujun Wen, Kuisheng Sun, Xiaopeng Zhao, Xiaofan Ren, Zhenquan He, Na Ding, Lin Ma, Fang X. The novel estrogen receptor GPER1 decreases epilepsy severity and susceptivity in the hippocampus after status epilepticus. Neuroscience letters. vol 728. 2021-05-17. PMID:32302699. |
the novel estrogen receptor gper1 decreases epilepsy severity and susceptivity in the hippocampus after status epilepticus. |
2021-05-17 |
2023-08-13 |
rat |
| Qian Jiang, Guo Tang, Jie Fu, Juan Yang, Tao Xu, Chang-Hong Tan, You Wang, Yang-Mei Che. Lim Kinase1 regulates seizure activity via modulating actin dynamics. Neuroscience letters. vol 729. 2021-05-14. PMID:32259557. |
our study showed that limk1 was upregulated in the hippocampal dentate gyrus (dg) of a pentylenetetrazol (ptz)-kindled epilepsy rat model. |
2021-05-14 |
2023-08-13 |
rat |
| Stephen Beesley, Thomas Sullenberger, Roshan Ailani, Cameron D'Orio, Mathew S Crockett, Sanjay S Kuma. d-Serine Intervention In The Medial Entorhinal Area Alters TLE-Related Pathology In CA1 Hippocampus Via The Temporoammonic Pathway. Neuroscience. vol 453. 2021-05-14. PMID:33197499. |
entrainment of the hippocampus by the medial entorhinal area (mea) in temporal lobe epilepsy (tle), the most common type of drug-resistant epilepsy in adults, is believed to be mediated primarily through the perforant pathway (pp), which connects stellate cells in layer (l) ii of the mea with granule cells of the dentate gyrus (dg) to drive the hippocampal tri-synaptic circuit. |
2021-05-14 |
2023-08-13 |
rat |
| F A Concepcion, M N Khan, J-D Ju Wang, A D Wei, J G Ojemann, A L Ko, Y Shi, J K Eng, J-M Ramirez, N P Poolo. HCN Channel Phosphorylation Sites Mapped by Mass Spectrometry in Human Epilepsy Patients and in an Animal Model of Temporal Lobe Epilepsy. Neuroscience. vol 460. 2021-05-14. PMID:33571596. |
because hyperpolarization-activated cyclic nucleotide-gated (hcn) ion channels modulate the excitability of cortical and hippocampal principal neurons, these channels play a key role in the hyperexcitability that occurs during the development of epilepsy after a brain insult, or epileptogenesis. |
2021-05-14 |
2023-08-13 |
human |
| Bożena Adamczyk, Karolina Węgrzyn, Tomasz Wilczyński, Justyna Maciarz, Natalia Morawiec, Monika Adamczyk-Sow. The Most Common Lesions Detected by Neuroimaging as Causes of Epilepsy. Medicina (Kaunas, Lithuania). vol 57. issue 3. 2021-05-14. PMID:33809843. |
this paper reviews the most common abnormalities, such as hippocampal sclerosis, malformations of cortical development and vascular malformation, detected by neuroimaging in patients with epilepsy to help understand the correlation between these changes and the course, treatment and prognosis of epilepsy. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yanyan Feng, Chaojun Duan, Zhaohui Luo, Wenbiao Xiao, Fafa Tia. Silencing miR-20a-5p inhibits axonal growth and neuronal branching and prevents epileptogenesis through RGMa-RhoA-mediated synaptic plasticity. Journal of cellular and molecular medicine. vol 24. issue 18. 2021-05-12. PMID:32779334. |
furthermore, in primary hippocampal neurons, the mir-20a-5p-rgma-rhoa pathway regulated axonal growth and neuronal branching; in the ptz-induced epilepsy model, silencing mir-20a-5p prevented epileptogenesis through rgma-rhoa-mediated synaptic plasticity but did not change mfs. |
2021-05-12 |
2023-08-13 |
Not clear |
| Anne M Rochtus, Richard D Goldstein, Ingrid A Holm, Catherine A Brownstein, Eduardo Pérez-Palma, Robin Haynes, Dennis Lal, Annapurna H Podur. The role of sodium channels in sudden unexpected death in pediatrics. Molecular genetics & genomic medicine. vol 8. issue 8. 2021-05-10. PMID:32449611. |
the presence of hippocampal abnormalities in many children with sudp suggests that epilepsy-related mechanisms may contribute to death, similar to sudden unexplained death in epilepsy. |
2021-05-10 |
2023-08-13 |
Not clear |
| Peng Wang, Yanchufei Zhang, Zihui Wang, Anyong Yang, Yuting Li, Qipeng Zhan. miR-128 regulates epilepsy sensitivity in mice by suppressing SNAP-25 and SYT1 expression in the hippocampus. Biochemical and biophysical research communications. vol 545. 2021-05-10. PMID:33571908. |
mir-128 regulates epilepsy sensitivity in mice by suppressing snap-25 and syt1 expression in the hippocampus. |
2021-05-10 |
2023-08-13 |
mouse |
| Cláudia A Valente, Francisco J Meda, Mafalda Carvalho, Ana M Sebastiã. A Model of Epileptogenesis in Rhinal Cortex-Hippocampus Organotypic Slice Cultures. Journal of visualized experiments : JoVE. issue 169. 2021-05-10. PMID:33818560. |
hippocampal organotypic slices are considered suitable to explore the basic mechanisms of epileptogenesis, but clinical research and animal models of epilepsy have suggested that the rhinal cortex, composed of perirhinal and entorhinal cortices, play a relevant role in seizure generation. |
2021-05-10 |
2023-08-13 |
Not clear |
| Ting-Ying Fu, Chen-Rui Ho, Chih-Hsiang Lin, Yan-Ting Lu, Wei-Che Lin, Meng-Han Tsa. Hippocampal Malrotation: A Genetic Developmental Anomaly Related to Epilepsy? Brain sciences. vol 11. issue 4. 2021-05-02. PMID:33916495. |
hippocampal malrotation: a genetic developmental anomaly related to epilepsy? |
2021-05-02 |
2023-08-13 |
Not clear |
| Ting-Ying Fu, Chen-Rui Ho, Chih-Hsiang Lin, Yan-Ting Lu, Wei-Che Lin, Meng-Han Tsa. Hippocampal Malrotation: A Genetic Developmental Anomaly Related to Epilepsy? Brain sciences. vol 11. issue 4. 2021-05-02. PMID:33916495. |
hippocampal malrotation (himal) is an increasingly recognized neuroimaging feature but the clinical correlation and significance in epilepsies remain under debate. |
2021-05-02 |
2023-08-13 |
Not clear |
| Yuehui Fan, Weiping Wang, Weifeng Li, Xianjun L. miR‑15a inhibits cell apoptosis and inflammation in a temporal lobe epilepsy model by downregulating GFAP. Molecular medicine reports. vol 22. issue 4. 2021-04-30. PMID:32945401. |
the function of mir‑15a was verified in vivo and in vitro by constructing a rat epilepsy model and using hippocampal neurons treated with mg2+‑free medium, respectively. |
2021-04-30 |
2023-08-13 |
rat |