| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shivum Desai, Ivy Y Chen, Christy Hom, Eric Doran, Dana D Nguyen, Ruth M Benca, Ira T Lott, Bryce A Mande. Insomnia Symptoms Are Associated with Measures of Functional Deterioration and Dementia Status in Adults with Down Syndrome at High Risk for Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024-06-14. PMID:38875029. |
while obstructive sleep apnea (osa) and insomnia symptoms in neurotypical populations are associated with alzheimer's disease (ad), their association with dementia in adults with down syndrome (ds) remains less clear, even though these symptoms are prevalent and treatable in ds. |
2024-06-14 |
2024-06-17 |
Not clear |
| Ujjayini Ghosh, Eric Tse, Hyunjun Yang, Marie Shi, Christoffer D Caro, Feng Wang, Gregory E Merz, Stanley B Prusiner, Daniel R Southworth, Carlo Condell. Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold. Acta neuropathologica communications. vol 12. issue 1. 2024-06-13. PMID:38867338. |
down syndrome (ds) is a common genetic condition caused by trisomy of chromosome 21. |
2024-06-13 |
2024-06-15 |
Not clear |
| Prakhar Bansal, Erin C Banda, Heather R Glatt-Deeley, Christopher E Stoddard, Jeremy W Linsley, Neha Arora, Cécile Deleschaux, Darcy T Ahern, Yuvabharath Kondaveeti, Rachael E Massey, Michael Nicouleau, Shijie Wang, Miguel Sabariego-Navarro, Mara Dierssen, Steven Finkbeiner, Stefan F Pinte. A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correction. Science advances. vol 10. issue 23. 2024-06-07. PMID:38848354. |
excess gene dosage from chromosome 21 (chr21) causes down syndrome (ds), spanning developmental and acute phenotypes in terminal cell types. |
2024-06-07 |
2024-06-10 |
human |
| Joan Lorente-Piera, Raquel Manrique-Huarte, Manuel Manrique, Francisco Javier Cervera-Pa. Clinical profile, otologic, and auditory outcomes in patients with Down syndrome. Acta otorrinolaringologica espanola. 2024-06-06. PMID:38823774. |
even though the incidence has decreased in recent years, down syndrome (ds) remains the most common chromosomal disorder today. |
2024-06-06 |
2024-06-10 |
Not clear |
| Francesco Ravaioli, Fiorenza Stagni, Sandra Guidi, Chiara Pirazzini, Paolo Garagnani, Alessandro Silvani, Giovanna Zoccoli, Renata Bartesaghi, Maria Giulia Bacalin. Increased hippocampal epigenetic age in the Ts65Dn mouse model of Down Syndrome. Frontiers in aging neuroscience. vol 16. 2024-06-05. PMID:38836050. |
down syndrome (ds) is a segmental progeroid genetic disorder associated with multi-systemic precocious aging phenotypes, which are particularly evident in the immune and nervous systems. |
2024-06-05 |
2024-06-07 |
mouse |
| Mohammed R Shaker, Andrii Slonchak, Bahaa Al-Mhanawi, Sean D Morrison, Julian D J Sng, Justin Cooper-White, Alexander A Khromykh, Ernst J Wolvetan. Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2. Science advances. vol 10. issue 23. 2024-06-05. PMID:38838150. |
why individuals with down syndrome (ds) are more susceptible to sars-cov-2-induced neuropathology remains elusive. |
2024-06-05 |
2024-06-08 |
Not clear |
| Abtahi Tishad, Siena Vadakal, Jay Talati, Mariam Louis, Rafik Jaco. Comprehensive Care for Adults with Down Syndrome in Primary Care Settings. Southern medical journal. vol 117. issue 6. 2024-06-03. PMID:38830582. |
this review article aims to bridge the knowledge gap in providing comprehensive care to adults with down syndrome (ds) in primary care settings. |
2024-06-03 |
2024-06-06 |
Not clear |
| Phoebe P Tchoua, Emily Clarke, Heather Wasser, Seema Agrawal, Rebecca Scothorn, Kelsey Thompson, Michaela Schenkelberg, Erik A Willi. The interaction between social determinants of health, health behaviors, and child's intellectual developmental diagnosis. medRxiv : the preprint server for health sciences. 2024-06-03. PMID:38826242. |
therefore, we examined the influence of sdoh and children's diagnosis (typically developing [td], down syndrome [ds], autism) on caregiver's self-report of meeting evidence-based health practices. |
2024-06-03 |
2024-06-05 |
Not clear |
| Kaoru Takasaki, Eric K Wafula, Sara S Kumar, David Smith, Alyssa L Gagne, Deborah L French, Christopher S Thom, Stella T Cho. Single-cell transcriptomics reveal synergistic and antagonistic effects of T21 and GATA1s on hematopoiesis. bioRxiv : the preprint server for biology. 2024-06-03. PMID:38826323. |
trisomy 21 (t21), or down syndrome (ds), is associated with baseline macrocytic erythrocytosis, thrombocytopenia, and neutrophilia, and transient abnormal myelopoiesis (tam) and myeloid leukemia of ds (ml-ds). |
2024-06-03 |
2024-06-05 |
Not clear |
| Jonathan M LaCombe, Kourtney Sloan, Jared R Thomas, Matthew P Blackwell, Isabella Crawford, Joseph M Wallace, Randall J Rope. Sex specific emergence of trisomic bioRxiv : the preprint server for biology. 2024-06-03. PMID:38826419. |
sex specific emergence of trisomic skeletal insufficiency affects all individuals with down syndrome (ds) or trisomy 21 (ts21) and may alter bone strength throughout development due to a reduced period of bone formation and early attainment of peak bone mass compared to typically developing individuals. |
2024-06-03 |
2024-06-05 |
mouse |
| Emilie Bochud-Fragnière, Gianni Lonchampt, Paola Bittolo, Giada Ehrensperger, Antonella Rita Circelli, Nicole Antonicelli, Floriana Costanzo, Deny Menghini, Stefano Vicari, Pamela Banta Lavenex, Pierre Lavene. Why do individuals with Williams syndrome or Down syndrome fail the Weather Prediction Task? Developmental psychobiology. vol 66. issue 5. 2024-05-29. PMID:38807263. |
williams syndrome (ws) and down syndrome (ds) are two neurodevelopmental disorders with distinct genetic origins characterized by mild to moderate intellectual disability. |
2024-05-29 |
2024-06-03 |
Not clear |
| Danielle Barreto E Silva, Camila de Castro Corrêa, Silke Anna Theresa Webe. Orofacial myofunctional and polysomnographic characteristics of children with Down syndrome and obstructive sleep apnea: a pilot study. CoDAS. vol 36. issue 3. 2024-05-29. PMID:38808857. |
to investigate oropharyngeal structures and functions in a pediatric population with down syndrome (ds) and obstructive sleep apnea (osa) and to correlate with the apnea/hypopnea index (ahi) and sleep questionnaires. |
2024-05-29 |
2024-06-03 |
Not clear |
| Ann-Charlotte E Granholm, Elisabet Englund, Anah Gilmore, Elizabeth Head, William H Yong, Sylvia E Perez, Samuel J Guzman, Eric D Hamlett, Elliott J Mufso. Neuropathological findings in Down syndrome, Alzheimer's disease and control patients with and without SARS-COV-2: preliminary findings. Acta neuropathologica. vol 147. issue 1. 2024-05-27. PMID:38801558. |
the sars-cov-2 virus that led to covid-19 is associated with significant and long-lasting neurologic symptoms in many patients, with an increased mortality risk for people with alzheimer's disease (ad) and/or down syndrome (ds). |
2024-05-27 |
2024-06-03 |
human |
| Jr-Jiun Liou, Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh, Nadim Farhat, Minjie Wu, Howard Aizenstein, Joseph M Mettenburg, William Yong, Elizabeth Head, Milos Ikonomovic, Tamer Ibrahim, Julia Kofle. Correlating hippocampal and amygdala volumes with neuropathological burden in neurodegenerative diseases using 7T postmortem MRI. medRxiv : the preprint server for health sciences. 2024-05-27. PMID:38798514. |
using 7t postmortem ex vivo mri, we explore the potential correlation of amygdala and hippocampal atrophy with neuropathological burden in both down syndrome (ds) and alzheimer's disease (ad) cohorts. |
2024-05-27 |
2024-05-31 |
human |
| Patricia López Resa, Esther Moraleda Sepúlved. Developmental Profile in Children Aged 3-6 Years: Down Syndrome vs. Autism Spectrum Disorder. Behavioral sciences (Basel, Switzerland). vol 14. issue 5. 2024-05-26. PMID:38785871. |
this research aims to compare the developmental profiles of children with autism spectrum disorder (asd) and children with down syndrome (ds) between the ages of 3 and 6 years. |
2024-05-26 |
2024-05-27 |
Not clear |
| Francesca Gorini, Alessio Coi, Anna Pierini, Nadia Assanta, Antonio Bottoni, Michele Santor. Hypothyroidism in Patients with Down Syndrome: Prevalence and Association with Congenital Heart Defects. Children (Basel, Switzerland). vol 11. issue 5. 2024-05-25. PMID:38790508. |
this population-based study aimed to assess the prevalence of congenital hypothyroidism (ch) and overt hypothyroidism (oh) and their association with congenital heart defects (chds) in patients with down syndrome (ds). |
2024-05-25 |
2024-05-27 |
human |
| Viviane Merzbach, Matthew Jewiss, Adrian Scruton, Dan Gordo. The Effects of Prescribed Physical and Cognitive Exercise on Life Satisfaction, Self-Efficacy and Mood States in Adults with Down Syndrome: The MinDSets Study. International journal of environmental research and public health. vol 21. issue 5. 2024-05-25. PMID:38791824. |
down syndrome (ds) is characterised by a duplication of chromosome-21 and is linked to co-occurring physical and mental health conditions, including low self-efficacy and disturbed mood states. |
2024-05-25 |
2024-05-27 |
human |
| Krista M Wilkinson, Savanna Brittlebank, Allison Barwise, Tara O'Neill Zimmerman, Janice Ligh. Visual fixation patterns to AAC displays are significantly correlated with motor selection for individuals with Down syndrome or individuals on the autism spectrum. Augmentative and alternative communication (Baltimore, Md. : 1985). 2024-05-24. PMID:38786201. |
ten individuals on the autism spectrum (as; study 1) and nine with down syndrome (ds; study 2) participated in a search task using simulated aac displays with a main visual scene display (vsd) and a navigation bar of thumbnail vsds. |
2024-05-24 |
2024-05-27 |
human |
| Lisa M Walter, Elizabeth A Kleeman, Marisha Shetty, Ahmad Bassam, Alyssa S Andiana, Knarik Tamanyan, Margot J Davey, Gillian M Nixon, Rosemary Sc Horn. The surge in heart rate and blood pressure at respiratory event termination is dampened in children with down syndrome. Sleep medicine. vol 119. 2024-05-24. PMID:38788315. |
children with down syndrome (ds) have a high prevalence of sleep disordered breathing (sdb) and altered cardiovascular autonomic control. |
2024-05-24 |
2024-05-27 |
Not clear |
| Borja Suarez-Villadat, Kabir Sadarangani, Rui Manuel Corredeira, Mario Veiga, Ariel Villagr. Swim, Strength, or Combined Programs: Effect on Health-Related Physical Fitness in Adolescents With Down Syndrome. Adapted physical activity quarterly : APAQ. 2024-05-16. PMID:38754859. |
the adolescent population with down syndrome (ds) appears to show higher levels of body fat and lower levels of cardiorespiratory fitness or muscle strength than their peers without disabilities. |
2024-05-16 |
2024-05-27 |
Not clear |