| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B K Trimble, P A Bair. Maternal age and Down syndrome: age-specific incidence rates by single-year intervals. American journal of medical genetics. vol 2. issue 1. 1984-07-17. PMID:162533. |
maternal age-specific risks of giving birth to a child with the down syndrome (ds) are given by single-year age intervals. |
1984-07-17 |
2023-08-11 |
Not clear |
| S Aymé, P Mercier, R Dallest, J F Matte. HLA and trisomy 21. Confirmation of a trend of restricted HLA heterogeneity in parents of Down syndrome children. American journal of human genetics. vol 36. issue 2. 1984-05-02. PMID:6231858. |
the down syndrome (ds) children did not show a significant association with a specific hla antigen. |
1984-05-02 |
2023-08-12 |
Not clear |
| K Iijima, K Morimoto, A Koizumi, M Higurashi, M Hirayam. Bleomycin-induced chromosomal aberrations and sister chromatid exchanges in Down lymphocyte cultures. Human genetics. vol 66. issue 1. 1984-04-24. PMID:6199286. |
peripheral blood lymphocytes from three patients with down syndrome (ds; trisomy 21; aged 5-6 years) and three age-matched control children were studied for the induction of chromosomal aberrations and sister chromatid exchanges (sces). |
1984-04-24 |
2023-08-12 |
Not clear |
| C Steinberg, E H Zackai, D L Eunpu, M T Mennuti, B S Emanue. Recurrence rate for de novo 21q21q translocation Down syndrome: a study of 112 families. American journal of medical genetics. vol 17. issue 2. 1984-04-18. PMID:6230935. |
recurrence of de novo gqgq down syndrome (ds) in nine reported families and the low frequency of this chromosome abnormality in the population prompted this multicenter study to examine recurrence rate. |
1984-04-18 |
2023-08-12 |
Not clear |
| V D Mottironi, E B Hook, A M Willey, I H Porter, R V Swift, N H Hatche. Decreased HLA heterogeneity in parents of children with Down syndrome. American journal of human genetics. vol 35. issue 6. 1984-01-07. PMID:6228137. |
hla-a and b antigens were determined in a study of 37 couples and their children with trisomy 21 down syndrome (ds), using a standard microlymphocytotoxicity test. |
1984-01-07 |
2023-08-12 |
Not clear |
| G O Roecker, C A Huethe. An analysis for paternal-age effect in Ohio's Down syndrome births, 1970-1980. American journal of human genetics. vol 35. issue 6. 1984-01-07. PMID:6228138. |
the purpose of this study was to analyze down syndrome (ds) births during 1970-1980 in the state of ohio for a paternal-age effect independent of maternal age. |
1984-01-07 |
2023-08-12 |
Not clear |
| J B Krakow, C B Kop. The effects of developmental delay on sustained attention in young children. Child development. vol 54. issue 5. 1983-12-20. PMID:6194941. |
using a videotaped free-play situation, we examined attention deployment behaviors of 3 groups: normally developing (nd), down syndrome (ds), and developmentally delayed with uncertain etiology (ue). |
1983-12-20 |
2023-08-12 |
human |
| C Turc-Carel, F Mugneret, I Sidane. [Constitutional chromosome anomalies and acute leukemia]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris. vol 59. issue 32. 1983-12-17. PMID:6314516. |
al, myeloblastic or lymphoblastic according to age are 18 to 20 times more frequent in down syndrome (ds) children than in non ds children. |
1983-12-17 |
2023-08-12 |
Not clear |
| E C Jenkins, C J Duncan, C E Wright, F M Giordano, L Wilbur, K Wisniewski, S L Sklower, J H French, C Jones, W T Brow. Atypical Down syndrome and partial trisomy 21. Clinical genetics. vol 24. issue 2. 1983-11-23. PMID:6225574. |
a case of "atypical" down syndrome (ds), where the proposita did not exhibit all of the clinical features of ds and had de novo partial trisomy 21, was studied. |
1983-11-23 |
2023-08-12 |
Not clear |
| B L Shapir. Down syndrome--a disruption of homeostasis. American journal of medical genetics. vol 14. issue 2. 1983-05-05. PMID:6220605. |
a major question in human genetics concerns the relationship between the extra chromosome material in the down syndrome (ds) and its effects. |
1983-05-05 |
2023-08-12 |
human |
| P H Jongbloet, A Mulder, A J Hamer. Seasonality of pre-ovulatory non-disjunction and the aetiology of Down syndrome. A European collaborative study. Human genetics. vol 62. issue 2. 1983-04-21. PMID:6219059. |
six series of patients with down syndrome (ds) from different european countries, altogether 287 cases, were divided into four categories according to parental origin of the additional chromosome 21 and meiotic division in which the nondisjunction had occurred. |
1983-04-21 |
2023-08-12 |
Not clear |
| C Turc-Carel, F Mugneret, I Sidane. [Constitutional chromosome abnormalities and acute leukemia]. Pathologie-biologie. vol 30. issue 9. 1983-03-11. PMID:6218469. |
al, myeloblastic or lymphoblastic according to age are 16 to 20 times more frequent in down syndrome (ds) children than in non ds children. |
1983-03-11 |
2023-08-12 |
Not clear |
| G R Gummere, C A Huether, P S Gartsid. An analysis for temporal variation in Down syndrome births in Ohio, 1970-1979. American journal of human genetics. vol 34. issue 6. 1983-02-14. PMID:6217744. |
our study investigates the epidemiology of down syndrome (ds) in the state of ohio during the 1970s. |
1983-02-14 |
2023-08-12 |
Not clear |
| J D McSwigan, D R Hanson, A Lubiniecki, L L Heston, J R Sheppar. Down syndrome fibroblasts are hyperresponsive to beta-adrenergic stimulation. Proceedings of the National Academy of Sciences of the United States of America. vol 78. issue 12. 1982-05-21. PMID:6278485. |
down syndrome (ds; trisomy 21) cells had an approximately 10-fold greater response to beta-adrenergic agonists than did either normal diploid skin fibroblasts or other aneusomic fibroblast strains (trisomy 13, 18, and 22). |
1982-05-21 |
2023-08-12 |
human |
| P H Jongbloet, R R Frants, A J Hamer. Parental alpha 1-antitrypsin (PI) types and meiotic nondisjunction in the aetiology of Down syndrome. Clinical genetics. vol 20. issue 4. 1982-05-21. PMID:6460570. |
in 100 children with down syndrome (ds), the parental origin of the supernumery chromosome 21 was investigated. |
1982-05-21 |
2023-08-12 |
Not clear |
| I Milstein-Moscati, W Beça. Occurrence of down syndrome and human sexual behavior. American journal of medical genetics. vol 9. issue 3. 1981-11-22. PMID:6456665. |
we analyzed the sexual habits of 80 mothers of normal children and of 33 mothers of children with the down syndrome (ds). |
1981-11-22 |
2023-08-12 |
human |
| D A Luthy, I Emanuel, H Hoehn, J G Hall, E K Power. Prenatal genetic diagnosis and elective abortion in women over 35: utilization and relative impact on the birth prevalence of Down syndrome in Washington State. American journal of medical genetics. vol 7. issue 3. 1981-04-21. PMID:6451173. |
we have examined the relative contributions of a population-based antenatal detection program and unrestricted elective abortion used by women 35 years old and over in washington state and king county for 1976--1977 to the declining birth prevalence of down syndrome (ds). |
1981-04-21 |
2023-08-12 |
Not clear |
| S Y Pi, R M Fineman, S D Wing, M Grunnet, G Cha. Holoprosencephaly in a Down syndrome child. American journal of medical genetics. vol 5. issue 2. 1980-09-23. PMID:6446857. |
gross malformation of the central nervous system (cns) is rare in down syndrome (ds). |
1980-09-23 |
2023-08-12 |
Not clear |
| E T Bers. Anatomical analysis of the developmental effects of aneuploidy in man: the Down syndrome. American journal of medical genetics. vol 5. issue 4. 1980-09-23. PMID:6446859. |
detailed anatomical dissections of five down syndrome (ds) bodies revealed a unique and consistent "internal phenotype" composed of: 1) variations in muscles, 2) peripheral artery variations, and 3) the presence of dilatations and nerve rootlets associated with the spinal accessory and first cervical nerves. |
1980-09-23 |
2023-08-12 |
Not clear |
| M J Seidenfeld, A Braitman, R M Antle. The determinants of mothers' knowledge of the Down syndrome before genetic counseling: part II. American journal of medical genetics. vol 6. issue 1. 1980-09-23. PMID:6446860. |
mothers coming for genetic counseling because they have an infant with the down syndrome (ds) vary in their amount of knowledge about the cause, recurrence risk, and options for dealing with the recurrence risk. |
1980-09-23 |
2023-08-12 |
Not clear |