| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alaa Al-Nemr, Shimaa Reffa. Effect of Pilates exercises on balance and gross motor coordination in children with Down syndrome. Acta neurologica Belgica. 2024-04-01. PMID:38558387. |
to investigate the effect of pilates exercises on balance and gross motor coordination in children with down syndrome (ds). |
2024-04-01 |
2024-04-04 |
Not clear |
| Mengmeng Jin, Ziyuan Ma, Rui Dang, Haiwei Zhang, Rachael Kim, Haipeng Xue, Jesse Pascual, Steven Finkbeiner, Elizabeth Head, Ying Liu, Peng Jian. A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimer's Disease. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559257. |
down syndrome (ds), or trisomy 21, is the most common genetic cause of ad. |
2024-04-01 |
2024-04-04 |
human |
| Anllely Fernandez, Md Rejaul Hoq, Grace I Hallinan, Daoyi Li, Sakshibeedu R Bharath, Frank S Vago, Xiaoqi Zhang, Kadir A Ozcan, Kathy L Newell, Holly J Garringer, Wen Jiang, Bernardino Ghetti, Ruben Vida. Cryo-EM structures of amyloid-β and tau filaments in Down syndrome. Nature structural & molecular biology. 2024-03-30. PMID:38553642. |
adult individuals with down syndrome (ds) develop alzheimer disease (ad). |
2024-03-30 |
2024-04-01 |
Not clear |
| b' Emanuele Rocco Villani, Graziano Onder, Emanuele Marzetti, Helio Coelho-Junior, Riccardo Calvani, Antonella Di Paola, Angelo Carf\\xc3\\xa. Body composition parameters and sarcopenia in adults with Down syndrome: a case-control study. Aging clinical and experimental research. vol 36. issue 1. 2024-03-29. PMID:38551714.' |
individuals with down syndrome (ds) experience premature aging. |
2024-03-29 |
2024-04-01 |
Not clear |
| Álvaro Fernández-Blanco, Cèsar Sierra, Clara Tejido, Mara Diersse. Beyond Quiescent and Active: Intermediate Microglial Transcriptomic States in a Mouse Model of Down Syndrome. International journal of molecular sciences. vol 25. issue 6. 2024-03-28. PMID:38542263. |
research on microglia in down syndrome (ds) has shown that microglial activation, increased inflammatory gene expression, and oxidative stress occur at different ages in ds brains. |
2024-03-28 |
2024-03-30 |
mouse |
| Huiru Zhao, Guiyu Lou, Yupu Shao, Tao Wang, Hongdan Wang, Qiannan Guo, Wenke Yang, Hongyan Liu, Shixiu Lia. Competing Endogenous RNAs Crosstalk in Hippocampus: A Potential Mechanism for Neuronal Developing Defects in Down Syndrome. Journal of molecular neuroscience : MN. vol 74. issue 2. 2024-03-27. PMID:38536538. |
down syndrome (ds) is the most example of aneuploidy, resulting from an additional copy of all or part of chromosome 21. |
2024-03-27 |
2024-03-30 |
Not clear |
| Matthew Beerse, Kaylee Larsen, Tasnuva Alam, Amy Talboy, Jianhua W. Joint kinematics and SPM analysis of gait in children with and without Down syndrome. Human movement science. vol 95. 2024-03-23. PMID:38520896. |
individuals with down syndrome (ds) walk with altered gait patterns compared to their typically developing (td) peers. |
2024-03-23 |
2024-03-26 |
Not clear |
| Ty Hergenreder, Tao Yang, Bing Y. The role of Down syndrome cell adhesion molecule in Down syndrome. Medical review (2021). vol 4. issue 1. 2024-03-22. PMID:38515781. |
down syndrome (ds) is caused by the presence of an extra copy of the entire or a portion of human chromosome 21 (hsa21). |
2024-03-22 |
2024-03-24 |
human |
| Ty Hergenreder, Tao Yang, Bing Y. The role of Down syndrome cell adhesion molecule in Down syndrome. Medical review (2021). vol 4. issue 1. 2024-03-22. PMID:38515781. |
among the genes located in the ds "critical region" of hsa21, down syndrome cell adhesion molecule (dscam) plays an important role in neuronal development. |
2024-03-22 |
2024-03-24 |
human |
| E Fucà, F Costanzo, P Galassi, L Celestini, D Valentini, S Vicar. Celiac disease in children and adolescents with Down syndrome: behavioural, adaptive and sleep profiles. Journal of intellectual disability research : JIDR. 2024-03-21. PMID:38509762. |
individuals with down syndrome (ds) exhibit higher risk for celiac disease (cd) than general population. |
2024-03-21 |
2024-03-23 |
Not clear |
| Daniel J Kats, Karen Donelan, Souvik Banerjee, Gert de Graaf, Ellen Skladzien, Brian Takashi Hooper, Rose Mordi, Tetiana Mykhailenko, Frank Buckley, Stephanie L Santoro, Vasiliki Patsiogiannis, Kavita Krell, Kelsey Haugen, Brian G Skotk. Results of inaugural international Down Syndrome Societal Services and Supports survey. Genetics in medicine : official journal of the American College of Medical Genetics. 2024-03-21. PMID:38512346. |
we previously designed the down syndrome societal services and supports survey (ds-4s) to measure country-specific supports for people with down syndrome (ds) across multiple life domains (healthcare, education, policy, independence, and community inclusion). |
2024-03-21 |
2024-03-23 |
Not clear |
| Tomohiko Sato, Kenichi Yoshida, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Ryunosuke Saiki, Masami Ojima, Yotaro Ochi, Seiya Mizuno, Masaharu Yoshihara, Tamayo Uechi, Naoya Kenmochi, Shiro Tanaka, Jun Matsubayashi, Kenta Kisai, Ko Kudo, Kentaro Yuzawa, Yuka Takahashi, Tatsuhiko Tanaka, Yohei Yamamoto, Akie Kobayashi, Takuya Kamio, Shinya Sasaki, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Hideki Muramatsu, Asahito Hama, Daisuke Hasegawa, Atsushi Sato, Katsuyoshi Koh, Shuhei Karakawa, Masao Kobayashi, Junichi Hara, Yuichi Taneyama, Chihaya Imai, Daiichiro Hasegawa, Naoto Fujita, Masahiro Yoshitomi, Shotaro Iwamoto, Genki Yamato, Satoshi Saida, Nobutaka Kiyokawa, Takao Deguchi, Masafumi Ito, Hidemasa Matsuo, Souichi Adachi, Yasuhide Hayashi, Takashi Taga, Akiko Moriya Saito, Keizo Horibe, Kenichiro Watanabe, Daisuke Tomizawa, Satoru Miyano, Satoru Takahashi, Seishi Ogawa, Etsuro It. Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms. Blood. 2024-03-21. PMID:38513239. |
transient abnormal myelopoiesis (tam) is a common complication in newborns with down syndrome (ds). |
2024-03-21 |
2024-03-24 |
Not clear |
| Debomoy K Lahiri, Deborah K Soko. Alzheimer's Drugs APPlication for Down syndrome? Ageing research reviews. 2024-03-21. PMID:38513771. |
accumulation of the amyloid β (aβ) peptide, derived from aβ precursor protein (app), is a trait of down syndrome (ds), as is early development of dementia like alzheimer's disease (ad). |
2024-03-21 |
2024-03-24 |
human |
| Frode Kibsgaard Larsen, R Asaad Baksh, Eimear McGlinchey, Ellen Melbye Langballe, Bessy Benejam, Jessica Beresford-Webb, Mary McCarron, Antonia Coppus, Segolene Falquero, Juan Fortea, Johannes Levin, Sandra V Loosli, Ruth Mark, Anne-Sophie Rebillat, Shahid Zaman, Andre Strydo. Age of Alzheimer's disease diagnosis in people with Down syndrome and associated factors: Results from the Horizon 21 European Down syndrome consortium. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-03-20. PMID:38506627. |
people with down syndrome (ds) have high risk of developing alzheimer's disease (ad). |
2024-03-20 |
2024-03-23 |
Not clear |
| Doug Chieffe, Christopher Hartnic. Neurostimulation for Pediatric Obstructive Sleep Apnea. Otolaryngologic clinics of North America. 2024-03-20. PMID:38508882. |
up to 80% of children with down syndrome (ds) are affected by obstructive sleep apnea (osa), and only 16% to 30% will have resolution of their osa with adenotonsillectomy. |
2024-03-20 |
2024-03-23 |
Not clear |
| Nicole T Baumer, Katherine G Pawlowski, Bo Zhang, Georgios Sideridi. Validation of factor structure of the neurodevelopmental parent report for outcome monitoring in down syndrome: confirmatory factor analysis. Frontiers in psychiatry. vol 15. 2024-03-20. PMID:38505792. |
the neurodevelopmental parent report for outcome monitoring (nd-prom), initially developed to monitor developmental and behavioral functions in children with autism spectrum disorder (asd), assesses symptoms across a wide range of domains relevant in down syndrome (ds). |
2024-03-20 |
2024-03-23 |
Not clear |
| Morgan Dykman, Madison Ernst, Tasya Rakasiwi, Amy Buros Stein, David J Satin, Kristen E Holland, Stephanie L Santoro, Jillian F Ror. Dermatology Life Quality Index survey in patients with Down syndrome and caregivers. Pediatric dermatology. 2024-03-19. PMID:38500261. |
down syndrome (ds) is associated with many dermatological conditions, including hidradenitis suppurativa, folliculitis, and alopecia areata. |
2024-03-19 |
2024-03-21 |
Not clear |
| Praveen N K Pitchan Velammal, Suryakumar Balasubramanian, Fathima Shehnaz Ayoobkhan, Gautham V K Mohan, Pearl Aggarwal, Ali A Rabaan, Syed A Khan, Farah Yasmin, Thoyaja Koritala, Salim R Suran. COVID-19 in patients with Down syndrome: A systematic review. Immunity, inflammation and disease. vol 12. issue 3. 2024-03-19. PMID:38501534. |
down syndrome (ds) is associated with multiple comorbid conditions and chronic immune dysfunction. |
2024-03-19 |
2024-03-21 |
Not clear |
| Sergi Llambrich, Birger Tielemans, Ellen Saliën, Marta Atzori, Kaat Wouters, Vicky Van Bulck, Mark Platt, Laure Vanherp, Nuria Gallego Fernandez, Laura Grau de la Fuente, Harish Poptani, Lieve Verlinden, Uwe Himmelreich, Anca Croitor, Catia Attanasio, Zsuzsanna Callaerts-Vegh, Willy Gsell, Neus Martínez-Abadías, Greetje Vande Veld. Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model. eLife. vol 12. 2024-03-18. PMID:38497812. |
down syndrome (ds) is characterized by skeletal and brain structural malformations, cognitive impairment, altered hippocampal metabolite concentration and gene expression imbalance. |
2024-03-18 |
2024-03-20 |
mouse |
| Hampus Hillerstrom, Richard Fisher, Matthew P Janicki, Brian Chicoine, Bradley T Christian, Anna Esbensen, Lucille Esralew, Juan Fortea, Sigan Hartley, Jason Hassenstab, Seth M Keller, Sharon Krinsky-McHale, Florence Lai, Johannes Levin, Mary McCarron, Eric McDade, Anne Sophie Rebillat, Herminia Diana Rosas, Wayne Silverman, Andre Strydom, Shahid H Zaman, Henrik Zetterber. Adapting prescribing criteria for amyloid-targeted antibodies for adults with Down syndrome. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-03-14. PMID:38480678. |
this overlooks adults with down syndrome (ds), who often experience dementia at a younger age and with different diagnostic assessment outcomes. |
2024-03-14 |
2024-03-16 |
Not clear |