| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kelley L Colvin, Kristine Wolter-Warmerdam, Francis Hickey, Michael E Yeage. Altered peripheral blood leukocyte subpopulations, function, and gene expression in children with Down Syndrome: Implications for respiratory tract infection. European journal of medical genetics. 2024-02-07. PMID:38325643. |
we tested the hypothesis that aberrant expression of hsa21-encoded interferon genes in peripheral blood immune cells would correlate to immune cell dysfunction in children with down syndrome (ds). |
2024-02-07 |
2024-02-10 |
Not clear |
| Eliza Gaweł, Diana Celebańska, Anna Zwierzchowsk. Differentiation of the body build and posture in the population of people with intellectual disabilities and Down Syndrome: a systematic review. BMC public health. vol 24. issue 1. 2024-02-07. PMID:38326795. |
the aim of the study was to identify the variables of the internal compensatory mechanisms that differentiate the body build and posture of people with down syndrome (ds) from the intellectual disability (id) population. |
2024-02-07 |
2024-02-10 |
Not clear |
| Maria Elisa Serrano, Eugene Kim, Bernard Siow, Da Ma, Loreto Rojo, Camilla Simmons, Darryl Hayward, Dorota Gibbins, Nisha Singh, Andre Strydom, Elizabeth M C Fisher, Victor L J Tybulewicz, Diana Cas. Investigating brain alterations in the Dp1Tyb mouse model of Down syndrome. Neurobiology of disease. vol 188. 2024-02-06. PMID:38317803. |
down syndrome (ds) is one of the most common birth defects and the most prevalent genetic form of intellectual disability. |
2024-02-06 |
2024-02-09 |
mouse |
| Joanna Pautonnier, Sylvie Goutte, Laurence Derain Dubourg, Justine Bacchetta, Bruno Ranchin, Muriel Rabilloud, Damien Sanlavill. Creatinine levels in French children with Down syndrome up to ten years old. European journal of pediatrics. 2024-02-06. PMID:38319403. |
assess creatinine levels in french children with down syndrome (ds) on the basis of the relationship between creatinine levels and age. |
2024-02-06 |
2024-02-09 |
Not clear |
| Rosa López-Hidalgo, Raúl Ballestín, Lorena Lorenzo, Sandra Sánchez, José Miguel Blasco-Ibáñez, Carlos Crespo, Juan Nacher, Emilio Vare. Early chronic fasudil treatment rescues hippocampal alterations in the Ts65Dn model for down syndrome. Neurochemistry international. 2024-02-03. PMID:38309665. |
down syndrome (ds) is the most common genetic disorder associated with intellectual disability. |
2024-02-03 |
2024-02-06 |
mouse |
| Keiichi Ishihara, Ryuto Sakoda, Masako Mizoguchi, Mitsugu Fujita, Chiami Moyama, Yuri Okutani, Kazuyuki Takata, Miwa Tanaka, Takashi Minami, Haruhiko Sago, Kazuhiro Yamakawa, Takuro Nakamura, Eri Kawashita, Satoshi Akiba, Susumu Nakat. Suppression of Anticancer research. vol 44. issue 2. 2024-02-02. PMID:38307564. |
suppression of individuals with down syndrome (ds), attributed to triplication of human chromosome 21 (hsa21), exhibit a reduced incidence of solid tumors. |
2024-02-02 |
2024-02-05 |
mouse |
| T Q Nguyen, C I Kerley, A P Key, A C Maxwell-Horn, Q S Wells, J L Neul, L E Cutting, B A Landma. Phenotyping Down syndrome: discovery and predictive modelling with electronic medical records. Journal of intellectual disability research : JIDR. 2024-02-02. PMID:38303157. |
individuals with down syndrome (ds) have a heightened risk for various co-occurring health conditions, including congenital heart disease (chd). |
2024-02-02 |
2024-02-04 |
Not clear |
| Iban Aldecoa, Isabel Barroeta, Steven L Carroll, Juan Fortea, Anah Gilmore, Stephen D Ginsberg, Samuel J Guzman, Eric D Hamlett, Elizabeth Head, Sylvia E Perez, Huntington Potter, Laura Molina-Porcel, Ruma Raha-Chowdhury, Thomas Wisniewski, William H Yong, Shahid Zaman, Sujay Ghosh, Elliott J Mufson, Ann-Charlotte Granhol. Down Syndrome Biobank Consortium: A perspective. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-01-25. PMID:38270275. |
individuals with down syndrome (ds) have a partial or complete trisomy of chromosome 21, resulting in an increased risk for early-onset alzheimer's disease (ad)-type dementia by early midlife. |
2024-01-25 |
2024-01-27 |
Not clear |
| Iban Aldecoa, Isabel Barroeta, Steven L Carroll, Juan Fortea, Anah Gilmore, Stephen D Ginsberg, Samuel J Guzman, Eric D Hamlett, Elizabeth Head, Sylvia E Perez, Huntington Potter, Laura Molina-Porcel, Ruma Raha-Chowdhury, Thomas Wisniewski, William H Yong, Shahid Zaman, Sujay Ghosh, Elliott J Mufson, Ann-Charlotte Granhol. Down Syndrome Biobank Consortium: A perspective. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-01-25. PMID:38270275. |
to address this challenge, we created an international consortium of brain banks focused on collecting and disseminating brain tissue from persons with ds throughout their lifespan, named the down syndrome biobank consortium (dsbc) consisting of 11 biobanking sites located in europe, india, and the usa. |
2024-01-25 |
2024-01-27 |
Not clear |
| Nandini Singh, Joan T Richtsmeier, Roger H Reeve. Comparative analysis of craniofacial shape in two mouse models of Down syndrome: Ts65Dn and TcMAC21. Journal of anatomy. 2024-01-24. PMID:38264931. |
mouse models are central to studying and understanding the genotypic-to-phenotypic outcomes of down syndrome (ds), a complex condition caused by an extra copy of the long arm of human chromosome 21. |
2024-01-24 |
2024-01-26 |
mouse |
| Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie Haugsten Hansen, Darryl Hayward, Ok-Ryul Song, Véronique Brault, Yann Herault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewic. Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine. vol 16. issue 731. 2024-01-24. PMID:38266108. |
down syndrome (ds) is caused by trisomy of human chromosome 21 (hsa21). |
2024-01-24 |
2024-01-27 |
mouse |
| Mahdie Ghaffarpour, Morteza Karami-Zarandi, Hossein Ali Rahdar, Seifu Gizaw Feyisa, Elahe Tak. Periodontal disease in down syndrome: Predisposing factors and potential non-surgical therapeutic approaches. Journal of clinical laboratory analysis. 2024-01-23. PMID:38254289. |
periodontal diseases (pds) have been documented to be significantly more prevalent and severe in patients with down syndrome (ds). |
2024-01-23 |
2024-01-25 |
Not clear |
| Antonio Muñoz-Llerena, Laura Ladrón-de-Guevara, Daniel Medina-Rebollo, Virginia Alcaraz-Rodrígue. Impact of Physical Activity on Autonomy and Quality of Life in Individuals with Down Syndrome: A Systematic Review. Healthcare (Basel, Switzerland). vol 12. issue 2. 2024-01-23. PMID:38255069. |
down syndrome (ds) is the most common genetic alteration in humans, resulting from the trisomy of chromosome 21. |
2024-01-23 |
2024-01-25 |
Not clear |
| Kaitlin Roehl, Carolyn Mead-Harvey, Heidi M Connolly, Joseph A Dearani, Felicia S Schaap, Susanna L Liljenstolpe, Linda B Osborn, C Charles Jain, Donald J Hagler, Francois Marcotte, David S Majdalan. Safety and Efficacy of Surgical and Percutaneous Cardiac Interventions for Adults With Down Syndrome. Mayo Clinic proceedings. Innovations, quality & outcomes. vol 8. issue 1. 2024-01-16. PMID:38226363. |
to assess risks and benefits of cardiac intervention in adults with down syndrome (ds). |
2024-01-16 |
2024-01-18 |
Not clear |
| Eri Shimizu, Keiko Goto-Hirano, Yumiko Motoi, Masami Arai, Nobutaka Hattor. Symptoms and age of prodromal Alzheimer's disease in Down syndrome: a systematic review and meta-analysis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2024-01-16. PMID:38228941. |
the diagnostic criteria for adult-onset alzheimer's disease (ad) in patients with down syndrome (ds) have not been standardised. |
2024-01-16 |
2024-01-19 |
Not clear |
| Stella Engsner, Kok Wai Giang, Mikael Dellborg, Maria Fedchenko, Peter Eriksson, Zacharias Mandalenaki. Impact of Down Syndrome on Survival Among Patients With Congenital Heart Disease. Journal of the American Heart Association. 2024-01-12. PMID:38214262. |
however, the impact of down syndrome (ds) in patients with chd is still debated. |
2024-01-12 |
2024-01-14 |
Not clear |
| Sujata Bardhan, Huiqing Li, Erika Tarver, Charlene Schramm, Marishka Brown, Linda Garcia, Bryanna Schwartz, Anna Mazzucco, Nikila Natarajan, Elizabeth Walsh, Laurie Ryan, Gail Pearson, Melissa A Paris. The National Institutes of Health INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project: Accelerating research discoveries for people with Down syndrome across the lifespan. American journal of medical genetics. Part C, Seminars in medical genetics. 2024-01-10. PMID:38197535. |
the national institutes of health (nih) has a long-standing history of support for research in down syndrome (ds). |
2024-01-10 |
2024-01-13 |
human |
| Sujata Bardhan, Huiqing Li, Erika Tarver, Charlene Schramm, Marishka Brown, Linda Garcia, Bryanna Schwartz, Anna Mazzucco, Nikila Natarajan, Elizabeth Walsh, Laurie Ryan, Gail Pearson, Melissa A Paris. The National Institutes of Health INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project: Accelerating research discoveries for people with Down syndrome across the lifespan. American journal of medical genetics. Part C, Seminars in medical genetics. 2024-01-10. PMID:38197535. |
in response to a 2018 congressional directive for a trans-nih initiative to address medical issues in ds, nih launched the include project (investigation of co-occurring conditions across the lifespan to understand down syndrome). |
2024-01-10 |
2024-01-13 |
human |
| B H Brugnaro, M F Pauletti, C R G Lima, B N Verdério, R I Fonseca-Angulo, B Romão-Silva, A C de Campos, P Rosenbaum, N A C F Roch. Relationship between sensory processing patterns and gross motor function of children and adolescents with Down syndrome and typical development: a cross-sectional study. Journal of intellectual disability research : JIDR. 2024-01-06. PMID:38183401. |
children and adolescents with down syndrome (ds) may experience impairments in sensory and motor skills that can be interrelated. |
2024-01-06 |
2024-01-09 |
Not clear |
| Nesreen Safwat El Feil, Heba S Elmahdy, Rasha Ahmed Elmahdy, Ahmed Abd-Elbasset Aboelezz, Heba S Dawoud, Mohammed Al-Beltag. Brain metabolic profile assessed by magnetic resonance spectroscopy in children with Down syndrome: Relation to intelligence quotient. World journal of clinical pediatrics. vol 12. issue 5. 2024-01-05. PMID:38178937. |
down syndrome (ds) is one of the most common causes of intellectual disability. |
2024-01-05 |
2024-01-07 |
Not clear |