| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Soula Danopoulos, Soumyaroop Bhattacharya, Caroline Cherry, Gail Deutsch, Thomas Mariani, Denise Al Ala. Transcriptional Characterization Suggests Accelerated Epithelial Differentiation in Trisomy 21 Lungs. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560281. |
down syndrome (ds), from trisomy 21 (t21), is the most common human chromosomal anomaly in the united states. |
2022-05-13 |
2023-08-13 |
human |
| Kendra M Prutton, John O Marentette, Brice A Leifheit, Hector Esquer, Daniel V LaBarbera, Colin C Anderson, Kenneth N Maclean, James R Roed. Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21. Free radical biology & medicine. 2022-05-10. PMID:35537597. |
the ubiquity of cognitive deficits and early onset alzheimer's disease in down syndrome (ds) has focused much ds ipsc-based research on neuron degeneration and regeneration. |
2022-05-10 |
2023-08-13 |
Not clear |
| Luisa Rodriguez, Catherine Dinauer, Gary Franci. Treatment of hypothyroidism in infants, children and adolescents. Trends in endocrinology and metabolism: TEM. 2022-05-10. PMID:35537910. |
these include children with congenital hypothyroidism (ch), low birth weight (lbw) and very low birth weight (vlbw), down syndrome (ds), subclinical hypothyroidism, and obesity. |
2022-05-10 |
2023-08-13 |
Not clear |
| Michael S Rafii, Olivier Sol, William C Mobley, Saskia Delpretti, Brian G Skotko, Anna D Burke, Marwan N Sabbagh, Shauna H Yuan, Robert A Rissman, Margaret Pulsifer, Casey Evans, A Carol Evans, Gregory Beth, Nicolas Fournier, Julian A Gray, Antonio Melo Dos Santos, Valerie Hliva, Marija Vukicevic, Marie Kosco-Vilbois, Johannes Streffer, Andrea Pfeifer, Howard H Feldma. Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome: A Phase 1b Randomized Clinical Trial. JAMA neurology. 2022-05-09. PMID:35532913. |
individuals with down syndrome (ds) are at high risk of developing alzheimer disease due to an increased dose of the amyloid precursor protein gene, app, which leads to increased levels of full-length app and its products, including amyloid-β (aβ). |
2022-05-09 |
2023-08-13 |
Not clear |
| Mohamed Ali Elshafey, Reham Saeed Alsakhaw. Inspiratory Muscle Training and Physical Fitness in Children with Down Syndrome: Randomized Control Trial. Archives of physical medicine and rehabilitation. 2022-05-09. PMID:35533737. |
to investigate the effect of inspiratory muscle training (imt) on physical fitness in children with down syndrome (ds). |
2022-05-09 |
2023-08-13 |
Not clear |
| Zhujie Gu, Said El Bouhaddani, Jeanine Houwing-Duistermaat, Hae-Won U. Investigating the impact of Down syndrome on methylation and glycomics with two-stage PO2PLS. Theoretical biology forum. vol 114. issue 1-2. 2022-05-03. PMID:35502729. |
down syndrome (ds) is a condition that leads to precocious and accelerated aging in affected subjects. |
2022-05-03 |
2023-08-13 |
human |
| Zehratul Quresh, Chinni Dharavat. Biochemical Serum Markers Influencing Maternal Age Risk for Down's Syndrome in Quadruple Marker. Cureus. vol 14. issue 3. 2022-05-02. PMID:35494969. |
maternal age is the primary risk factor associated with down syndrome (ds) in the fetus. |
2022-05-02 |
2023-08-13 |
Not clear |
| Hiroyuki Sawatari, Anita Rahmawati, Nobuko Moriyama, Kanae Fujita, Tomoko Ohkusa, Tomoko Nao, Nobuko Hashiguchi, Mari Nishizaka, Shin-Ichi Ando, Akiko Chishak. Characteristics of sleep-disordered breathing in children with down syndrome - A comparison with typically developing children. Sleep medicine: X. vol 4. 2022-05-02. PMID:35495734. |
compared with typically developing control children (cc), children with down syndrome (ds) frequently exhibit sleep-disordered breathing (sdb) and unusual sleep postures (usps). |
2022-05-02 |
2023-08-13 |
Not clear |
| Alessandra C Martini, Thomas J Gross, Elizabeth Head, Mark Mapston. Beyond amyloid: Immune, cerebrovascular, and metabolic contributions to Alzheimer disease in people with Down syndrome. Neuron. 2022-04-26. PMID:35472307. |
people with down syndrome (ds) have increased risk of alzheimer disease (ad), presumably conferred through genetic predispositions arising from trisomy 21. |
2022-04-26 |
2023-08-13 |
Not clear |
| Emily K Schworer, Ameena Ahmed, Lori Hogenkamp, Shelby Moore, Anna J Esbense. Associations among co-occurring medical conditions and cognition, language, and behavior in Down syndrome. Research in developmental disabilities. vol 126. 2022-04-25. PMID:35468571. |
specific medical conditions are more prevalent in down syndrome (ds) compared to the general population. |
2022-04-25 |
2023-08-13 |
Not clear |
| Michela Sali, Angelo Carfì, Antonella Di Paola, Maria Pereyra Boza, Giuseppe Zampino, Maurizio Sanguinetti, Francesco Landi, Graziano Onde. SARS-CoV-2 vaccine humoral response in adults with down syndrome. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2022-04-24. PMID:35461998. |
people with down syndrome (ds) are particularly vulnerable to covid-19 and show altered immune response to vaccination. |
2022-04-24 |
2023-08-13 |
Not clear |
| Marta Teresa García-García, Pedro Diz-Dios, María Teresa Abeleira-Pazos, Jacobo Limeres-Posse, Eliane García-Mato, Iván Varela-Aneiros, Mercedes Outumuro-Rial, Márcio Diniz-Freita. Cranial-Vertebral-Maxillary Morphological Integration in Down Syndrome. Biology. vol 11. issue 4. 2022-04-23. PMID:35453698. |
the objective of this study was to determine the relationships between the dimensions of different cranial-cervical-facial structures in patients with down syndrome (ds). |
2022-04-23 |
2023-08-13 |
Not clear |
| Anke Hüls, Patrick T Feany, Sophia Isabella Zisman, Alberto C S Costa, Mara Dierssen, Robert Balogh, Stefania Bargagna, Nicole T Baumer, Ana Claudia Brandão, Angelo Carfi, Brian Allen Chicoine, Sujay Ghosh, Monica Lakhanpaul, Johannes Levin, Yona Lunsky, Coral Manso, Eitan Okun, Diego Real de Asua, Anne-Sophie Rebillat, Tilman R Rohrer, Giuseppina Sgandurra, Diletta Valentini, Stephanie L Sherman, Andre Strydom, On Behalf Of The Trisomy Research Society Covid-Initiativ. COVID-19 Vaccination of Individuals with Down Syndrome-Data from the Trisomy 21 Research Society Survey on Safety, Efficacy, and Factors Associated with the Decision to Be Vaccinated. Vaccines. vol 10. issue 4. 2022-04-23. PMID:35455279. |
individuals with down syndrome (ds) are among the groups with the highest risk for severe covid-19. |
2022-04-23 |
2023-08-13 |
human |
| Alejandra Rodríguez-Ortiz, Julio César Montoya-Villegas, Felipe García-Vallejo, Yecid Mina-Pa. Integrated Quantitative Neuro-Transcriptome Analysis of Several Brain Areas in Human Trisomy 21. Genes. vol 13. issue 4. 2022-04-23. PMID:35456434. |
although down syndrome (ds) is the most frequent human chromosomal disorder and it causes mainly intellectual disability, its clinical presentation is complex and variable. |
2022-04-23 |
2023-08-13 |
human |
| Juliana Muñoz-Ortiz, Jesús David Charry-Sánchez, Isabella Bechara-Arango, Mariana Blanco-Becerra, Claudia Talero-Gutiérrez, Marcela Gomez-Suarez, Alejandra de-la-Torr. Prevalence of ophthalmological manifestations in pediatric and adolescent populations with Down syndrome: a systematic review of the literature. Systematic reviews. vol 11. issue 1. 2022-04-23. PMID:35459223. |
down syndrome (ds) is a chromosomal anomaly that is characterized by an extra chromosome 21. |
2022-04-23 |
2023-08-13 |
Not clear |
| Yixing Wu, Nicole R West, Anita Bhattacharyya, Frances K Wisema. Cell models for Down syndrome-Alzheimer's disease research. Neuronal signaling. vol 6. issue 1. 2022-04-22. PMID:35449591. |
down syndrome (ds) is the most common chromosomal abnormality and leads to intellectual disability, increased risk of cardiac defects, and an altered immune response. |
2022-04-22 |
2023-08-13 |
human |
| S Amatori, D Sisti, F Perroni, G Brandi, M B L Rocchi, E Gobb. Physical activity, sedentary behaviour and screen time among youths with Down syndrome during the COVID-19 pandemic. Journal of intellectual disability research : JIDR. 2022-04-21. PMID:35445779. |
the covid-19-related restrictions hampered habitual physical activity (pa), particularly affecting the more vulnerable, such as people with down syndrome (ds). |
2022-04-21 |
2023-08-13 |
Not clear |
| Julie M Rogers, Amy L Weaver, Rachel D Havye. Down Syndrome Cures: Perspectives of People With Down Syndrome and Their Parents. American journal on intellectual and developmental disabilities. vol 127. issue 3. 2022-04-20. PMID:35443053. |
down syndrome (ds) research is advancing rapidly, yet efforts have raised ethical questions. |
2022-04-20 |
2023-08-13 |
Not clear |
| Sandra Giménez, Ariadna Farre, Fátima Morente, Laura Videla, Marta Gutiérrez, Susana Clos, Ana Fernández, Marta Blanco, Miren Altuna, Jordi Pegueroles, Amparo Asensio, Bessy Benejam, Mar Batista, Isabel Barroeta, Ana Fortuna, Juan Fortea, Mercedes Mayo. Feasibility and Long-Term Compliance to Continuous Positive Airway Pressure Treatment in Adults With Down Syndrome, a Genetic Form of Alzheimer's Disease. Frontiers in neuroscience. vol 16. 2022-04-18. PMID:35431793. |
down syndrome (ds) is a genetic form of alzheimer's disease (ad) with a high prevalence of obstructive sleep apnea (osa). |
2022-04-18 |
2023-08-13 |
Not clear |
| Anna Poliner, Chenge Mahomva, Chelsea Williams, Kristan Alfonso, Samantha Anne, Mary Musso, Yi-Chun Carol Li. Prevalence and surgical management of cholesteatoma in Down Syndrome children. International journal of pediatric otorhinolaryngology. vol 157. 2022-04-17. PMID:35430436. |
the objective was to report the outcomes of surgical management of cholesteatoma in down syndrome (ds) children and to determine the prevalence of cholesteatoma in ds children at three academic tertiary care centers. |
2022-04-17 |
2023-08-13 |
Not clear |