| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Jor. Red cell folate status among a subset of Canadian children with Down Syndrome post-fortification. Journal of intellectual disability research : JIDR. 2022-03-10. PMID:35266234. |
trisomy 21 or down syndrome (ds) is associated with altered methylation pathways. |
2022-03-10 |
2023-08-13 |
Not clear |
| Elisa Fucà, Floriana Costanzo, Luciana Ursumando, Stefano Vicar. Parenting Stress in Mothers of Children and Adolescents with Down Syndrome. Journal of clinical medicine. vol 11. issue 5. 2022-03-10. PMID:35268278. |
parents of children with intellectual disability, including down syndrome (ds), show higher levels of parenting stress than parents of typically developing children. |
2022-03-10 |
2023-08-13 |
Not clear |
| Sonia Cañizares-Prado, Jorge Molina-López, María Trinidad Moya, Elena Planell. Oral Function and Eating Habit Problems in People with Down Syndrome. International journal of environmental research and public health. vol 19. issue 5. 2022-03-10. PMID:35270327. |
down syndrome (ds) is a genetic disorder in which there is an increased risk of developing clinical comorbidities that require regular attention: health problems, alterations in maxillomandibular development, chewing and swallowing problems, as well as dietary habits that may influence diet and nutritional status. |
2022-03-10 |
2023-08-13 |
Not clear |
| Elvio Boato, Geiziane Melo, Mário Filho, Eduardo Moresi, Carla Lourenço, Rosana Tristã. The Use of Virtual and Computational Technologies in the Psychomotor and Cognitive Development of Children with Down Syndrome: A Systematic Literature Review. International journal of environmental research and public health. vol 19. issue 5. 2022-03-10. PMID:35270648. |
individuals with down syndrome (ds) have numerous comorbidities due to trisomy 21. |
2022-03-10 |
2023-08-13 |
Not clear |
| Deborah Kathleen Rose, Lauren Chamberlain, Jeffrey Ashton, Shadi Yaghi, Erik F Hauck, Brian Mac Gror. Moyamoya syndrome in a young person with Down syndrome: diagnostic and therapeutic considerations. BMJ case reports. vol 15. issue 3. 2022-03-05. PMID:35246432. |
an 18-year-old woman with a history of down syndrome (ds) presented with left upper extremity weakness. |
2022-03-05 |
2023-08-13 |
Not clear |
| Masato Tanaka, Sumeet Sonawane, Yoshihiro Fujiwara, Koji Uotani, Shinya Arataki, Taro Yamauchi, Youchen Ye, Haruo Misaw. C-arm Free O-arm Navigated Posterior Atlantoaxial Fixation in Down Syndrome: A Technical Note. Acta medica Okayama. vol 76. issue 1. 2022-03-03. PMID:35237001. |
the surgical treatment of pediatric atlantoaxial subluxation (aas) in down syndrome (ds) remains technically challenging due to radiation exposure and complications such as vertebral artery injury and nonunion. |
2022-03-03 |
2023-08-13 |
Not clear |
| Qiuyang Zheng, Beibei Song, Guilin Li, Fang Cai, Meiling Wu, Yingjun Zhao, LuLin Jiang, Tiantian Guo, Mingyu Shen, Huan Hou, Ying Zhou, Yini Zhao, Anjie Di, Lishan Zhang, Fanwei Zeng, Xiu-Fang Zhang, Hong Luo, Xian Zhang, Hongfeng Zhang, Zhiping Zeng, Timothy Y Huang, Chen Dong, Hong Qing, Yun Zhang, Qing Zhang, Xu Wang, Yili Wu, Huaxi Xu, Weihong Song, Xin Wan. USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation. The Journal of clinical investigation. vol 132. issue 5. 2022-03-01. PMID:35229730. |
down syndrome (ds), or trisomy 21, is one of the critical risk factors for early-onset alzheimer's disease (ad), implicating key roles for chromosome 21-encoded genes in the pathogenesis of ad. |
2022-03-01 |
2023-08-13 |
mouse |
| Carol A Boliek, Angela Halpern, Keren Hernandez, Cynthia M Fox, Lorraine Rami. Intensive Voice Treatment (Lee Silverman Voice Treatment [LSVT LOUD]) for Children With Down Syndrome: Phase I Outcomes. Journal of speech, language, and hearing research : JSLHR. 2022-03-01. PMID:35230877. |
this study examined the effects of an intensive voice treatment lee silverman voice treatment (lsvt loud) on children with down syndrome (ds) and motor speech disorders. |
2022-03-01 |
2023-08-13 |
Not clear |
| Sunil Malik, Aarti Kathuri. COVID-19 infection in a Down syndrome child. Sudanese journal of paediatrics. vol 21. issue 2. 2022-02-28. PMID:35221430. |
children with down syndrome (ds) have increase mortality rates from covid-19 compared to the general pediatric population. |
2022-02-28 |
2023-08-13 |
Not clear |
| Daphne Peeters, Ingrid Pico-Knijnenburg, Douwe Wieringa, Mandana Rad, Roos Cuperus, Madelon Ruige, Frank Froeling, Gerda W Zijp, Mirjam van der Burg, Gertjan J A Driesse. AKT Hyperphosphorylation and T Cell Exhaustion in Down Syndrome. Frontiers in immunology. vol 13. 2022-02-28. PMID:35222360. |
down syndrome (ds) is associated with increased susceptibility to infections, auto-immunity, immunodeficiency and haematological malignancies. |
2022-02-28 |
2023-08-13 |
Not clear |
| Sergi Llambrich, Rubèn González, Julia Albaigès, Jens Wouters, Fopke Marain, Uwe Himmelreich, James Sharpe, Mara Dierssen, Willy Gsell, Neus Martínez-Abadías, Greetje Vande Veld. Multimodal Frontiers in medicine. vol 9. 2022-02-28. PMID:35223915. |
using the ts65dn mouse model of down syndrome (ds) as a case example, we performed the first longitudinal assessment of brain, skull and neurobehavioral development to determine alterations in the coordinated morphogenesis of brain and skull. |
2022-02-28 |
2023-08-13 |
mouse |
| Malini Rammohan, Ethan Harris, Rahul S Bhansali, Emily Zhao, Loretta S Li, John D Crispin. The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target. Oncogene. 2022-02-27. PMID:35220406. |
due to its localization on chromosome 21, the biological significance of dyrk1a was initially characterized in the pathogenesis of down syndrome (ds) and related neurodegenerative diseases. |
2022-02-27 |
2023-08-13 |
Not clear |
| Carolina Monteiro Leite de Castro, Carolina Oliveto Bastos Pereira, Joissy Aprigio, Marcelo A Costa Lima, Márcia G Ribeiro, Márcia Rodrigues Amori. Aurora kinase genetic polymorphisms: an association study in Down syndrome and spontaneous abortion. Human cell. 2022-02-26. PMID:35218477. |
aneuploidies, such as down syndrome (ds), are the leading cause of pregnancy loss. |
2022-02-26 |
2023-08-13 |
Not clear |
| Sonali P Barwe, Aimy Sebastian, Ishnoor Sidhu, Edward Anders Kolb, Anilkumar Gopalakrishnapilla. Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of Cells. vol 11. issue 4. 2022-02-25. PMID:35203280. |
modeling down syndrome myeloid leukemia by sequential introduction of children with down syndrome (ds) have a high risk for acute myeloid leukemia (ds-ml). |
2022-02-25 |
2023-08-13 |
Not clear |
| Benjamin Holfelder, Thomas Jürgen Klotzbier, Nadja Schot. Dual-Task Interference in Children with Down Syndrome and Chronological and Mental Age-Matched Healthy Controls. Children (Basel, Switzerland). vol 9. issue 2. 2022-02-25. PMID:35204912. |
on the assumption that motor actions result from the interaction between cognitive, perceptual, and neurological mechanisms, neuromotor dysfunction-such as in children with down syndrome (ds)-is expected to affect the central coordination processes required for dual-task (dt) performance. |
2022-02-25 |
2023-08-13 |
Not clear |
| Federico Quinzi, Giuseppe Vannozzi, Valentina Camomilla, Maria Francesca Piacentini, Florin Boca, Eric Bortels, Eva Kathrein, Adrian Magyar, Fabio Verdone, Paola Sbriccol. Motor Competence in Individuals with Down Syndrome: Is an Improvement Still Possible in Adulthood? International journal of environmental research and public health. vol 19. issue 4. 2022-02-25. PMID:35206339. |
in adults with down syndrome (ds), mc has been poorly addressed, resulting in a limited understanding of the possibility to improve mc over time. |
2022-02-25 |
2023-08-13 |
Not clear |
| Chiara Locatelli, Sara Onnivello, Caterina Gori, Giuseppe Ramacieri, Francesca Pulina, Chiara Marcolin, Renzo Vianello, Beatrice Vione, Maria Caracausi, Maria Chiara Pelleri, Lorenza Vitale, Gian Luca Pirazzoli, Guido Cocchi, Luigi Corvaglia, Pierluigi Strippoli, Francesca Antonaros, Allison Piovesan, Silvia Lanfranch. A reassessment of Jackson's checklist and identification of two Down syndrome sub-phenotypes. Scientific reports. vol 12. issue 1. 2022-02-25. PMID:35210468. |
down syndrome (ds) is characterised by several clinical features including intellectual disability (id) and craniofacial dysmorphisms. |
2022-02-25 |
2023-08-13 |
human |
| Fahmida Moni, Melissa E Petersen, Fan Zhang, Patrick J Lao, Molly E Zimmerman, Yian Gu, José Gutierrez, Batool Rizvi, Krystal K Laing, Kay C Igwe, Mithra Sathishkumar, David Keator, Howard Andrews, Sharon Krinsky-McHale, Elizabeth Head, Joseph H Lee, Florence Lai, Michael A Yassa, H Diana Rosas, Wayne Silverman, Ira T Lott, Nicole Schupf, Sid O'Bryant, Adam M Brickma. Probing the proteome to explore potential correlates of increased Alzheimer's-related cerebrovascular disease in adults with Down syndrome. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022-02-25. PMID:35212182. |
cerebrovascular disease is associated with symptoms and pathogenesis of alzheimer's disease (ad) among adults with down syndrome (ds). |
2022-02-25 |
2023-08-13 |
human |
| Juliet A Moncaster, Robert D Moir, Mark A Burton, Oliver Chadwick, Olga Minaeva, Victor E Alvarez, Maria Ericsson, John I Clark, Ann C McKee, Rudolph E Tanzi, Lee E Goldstei. Alzheimer's disease amyloid-β pathology in the lens of the eye. Experimental eye research. 2022-02-24. PMID:35202705. |
subsequent research identified aβ lens pathology as the molecular origin of the distinctive cataracts in down syndrome (ds, trisomy 21), a chromosomal disorder invariantly associated with early-onset aβ accumulation and aβ amyloidopathy in the brain. |
2022-02-24 |
2023-08-13 |
mouse |
| Raza Jamal, Jonathan LaCombe, Roshni Patel, Matthew Blackwell, Jared R Thomas, Kourtney Sloan, Joseph M Wallace, Randall J Rope. Increased dosage and treatment time of Epigallocatechin-3-gallate (EGCG) negatively affects skeletal parameters in normal mice and Down syndrome mouse models. PloS one. vol 17. issue 2. 2022-02-23. PMID:35196359. |
bone abnormalities affect all individuals with down syndrome (ds) and are linked to abnormal expression of dyrk1a, a gene found in three copies in people with ds and ts65dn ds model mice. |
2022-02-23 |
2023-08-13 |
mouse |