| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Benjamen Wang, Justin Verrocchi, Danny Liew, Dominica Zentne. Does Down Syndrome influence the outcomes of congenital cardiac surgery? A systematic review and meta-analysis. European heart journal. Quality of care & clinical outcomes. 2022-05-25. PMID:35612980. |
congenital cardiac surgery for individuals with down syndrome (ds) has historically occurred at reduced frequency. |
2022-05-25 |
2023-08-13 |
Not clear |
| Thirachit Chotsampancharoen, Shevachut Chavananon, Pornpun Sripornsawan, Natsaruth Songthawee, Edward B McNei. Transient abnormal myelopoiesis in Down syndrome: Experience of long term follow up from a single tertiary center in Thailand. Pediatric hematology and oncology. 2022-05-24. PMID:35608385. |
transient abnormal myelopoiesis (tam) is a unique disease occurring in down syndrome (ds) infants from which most patients have spontaneous remission. |
2022-05-24 |
2023-08-13 |
Not clear |
| Helen Wong, Jordan M Buck, Curtis Borski, Jessica T Pafford, Bailey N Keller, Ryan A Milstead, Jessica L Hanson, Jerry A Stitzel, Charles A Hoeffe. RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimer's disease, and normative aging. Journal of neurodevelopmental disorders. vol 14. issue 1. 2022-05-24. PMID:35610565. |
regulator of calcineurin 1 (rcan1) is overexpressed in down syndrome (ds), but rcan1 levels are also increased in alzheimer's disease (ad) and normal aging. |
2022-05-24 |
2023-08-13 |
Not clear |
| Feyzullah Necati Arslan, Derya Gumus Dogan, Sinem Kortay Canaloglu, Senay Guven Baysal, Raikan Buyukavci, Mehmet Akif Buyukavc. Effects of early physical therapy on motor development in children with Down syndrome. Northern clinics of Istanbul. vol 9. issue 2. 2022-05-18. PMID:35582517. |
the objective of the study was to compare the motor development of children with down syndrome (ds) who received physical therapy (pt) and did not receive pt, and to show the effect of pt programs started before the age of one on movement development. |
2022-05-18 |
2023-08-13 |
Not clear |
| Lisbeth Jönsson, Christina Olsson Tyby, Sara Hullfors, Pia Lundqvis. Mothers of children with down syndrome: A qualitative study of experiences of breastfeeding and breastfeeding support. Scandinavian journal of caring sciences. 2022-05-18. PMID:35582826. |
children with down syndrome (ds) are breastfed to a lesser extent than infants in general, despite research showing that it is possible for these children to breastfeed successfully. |
2022-05-18 |
2023-08-13 |
Not clear |
| Randall J Roper, Charles R Goodlet. A new Down syndrome rat model races forward. Trends in genetics : TIG. 2022-05-17. PMID:35581033. |
animal models of down syndrome (ds) provide an essential resource for understanding genetic, cellular, and molecular contributions to traits associated with trisomy 21 (ts21). |
2022-05-17 |
2023-08-13 |
rat |
| Francesco Ravaioli, Michele Zampieri, Luca Morandi, Chiara Pirazzini, Camilla Pellegrini, Sara De Fanti, Noémie Gensous, Gian Luca Pirazzoli, Luisa Sambati, Alessandro Ghezzo, Fabio Ciccarone, Anna Reale, Daniela Monti, Stefano Salvioli, Paola Caiafa, Miriam Capri, Alexander Bürkle, Maria Moreno-Villanueva, Paolo Garagnani, Claudio Franceschi, Maria Giulia Bacalin. DNA Methylation Analysis of Ribosomal DNA in Adults With Down Syndrome. Frontiers in genetics. vol 13. 2022-05-16. PMID:35571061. |
as ribosomal genes (rdna) are organized in repeated clusters on chromosomes 13, 14, 15, 21, and 22, trisomy of chromosome 21 confers an excess of rdna copies to persons with down syndrome (ds). |
2022-05-16 |
2023-08-13 |
human |
| Qingting Bu, Rong Qiang, Hua Cheng, Anmin Wang, Huangtao Chen, Zhenyu Pa. Analysis of the Global Disease Burden of Down Syndrome Using YLDs, YLLs, and DALYs Based on the Global Burden of Disease 2019 Data. Frontiers in pediatrics. vol 10. 2022-05-16. PMID:35573954. |
this study aimed to determine down syndrome (ds) burden using years lived with disability (ylds), years of life lost (ylls), disability-adjusted life years (dalys), and the trends in these parameters. |
2022-05-16 |
2023-08-13 |
Not clear |
| Imran Ali Kha. Role of Adenotonsillectomy and Tonsillectomy in Children with Down Syndrome Who Develop Obstructive Sleep Apnea by Obesity as a Risk Factor. International journal of pediatrics. vol 2022. 2022-05-16. PMID:35574039. |
down syndrome (ds) or trisomy 21 is caused due to the presence of additional chromosome 21 in humans. |
2022-05-16 |
2023-08-13 |
Not clear |
| Justin Godown, Darlene Fountain, Neha Bansal, Rebecca Ameduri, Susan Anderson, Gary Beasley, Danielle Burstein, Kenneth Knecht, Kimberly Molina, Sherry Pye, Marc Richmond, Joseph A Spinner, Kae Watanabe, Shawn West, Zdenka Reinhardt, Janet Scheel, Simon Urschel, Chet Villa, Seth A Hollande. Heart Transplantation in Children With Down Syndrome. Journal of the American Heart Association. 2022-05-16. PMID:35574952. |
background children with down syndrome (ds) have a high risk of cardiac disease that may prompt consideration for heart transplantation (htx). |
2022-05-16 |
2023-08-13 |
Not clear |
| Audrey Landuran, Hélène Sauzéon, Charles Consel, Bernard N'Kaou. Evaluation of a smart home platform for adults with Down syndrome. Assistive technology : the official journal of RESNA. 2022-05-16. PMID:35576554. |
people with down syndrome (ds) encounter difficulties in their daily lives. |
2022-05-16 |
2023-08-13 |
Not clear |
| Laura E Hawley, Faith Prochaska, Megan Stringer, Charles R Goodlett, Randall J Rope. Sexually dimorphic DYRK1A overexpression on postnatal day 15 in the Ts65Dn mouse model of Down syndrome: Effects of pharmacological targeting on behavioral phenotypes. Pharmacology, biochemistry, and behavior. 2022-05-16. PMID:35576991. |
the neurotypical spatiotemporal patterns of gene expression are disrupted in down syndrome (ds) by trisomy of human chromosome 21 (hsa21), resulting in altered behavioral development and brain circuitry. |
2022-05-16 |
2023-08-13 |
mouse |
| Juan-Carlos Hernández-Rodríguez, Guiovana-Fernanda Osorio-Gómez, Juan Ortiz-Álvarez, José-Antonio Lebrón-Martín, Julián Conejo-Mir, José-Juan Pereyra-Rodrígue. Hidradenitis suppurativa and Down syndrome in a single-centre sample: A cross-sectional study. The Australasian journal of dermatology. 2022-05-14. PMID:35567765. |
down syndrome (ds) has been related to a higher risk of hidradenitis suppurativa (hs). |
2022-05-14 |
2023-08-13 |
human |
| Cynthia Anyaoku, Lara R DeRuisseau, Josef Brandaue. Evidence of Mitochondrial Impairment in a Mouse Model of Down Syndrome. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35553593. |
down syndrome (ds) is typically the result of triplication of the 21st chromosome. |
2022-05-13 |
2023-08-13 |
mouse |
| Laura D Flores, Yana Pryakhina, Michael H Tomasson, Melissa L Bates, Lara R DeRuissea. Sex Differences and Cardiovascular Diseases in Down Syndrome. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554720. |
congenital heart disease and cardiovascular disease are the leading causes of death for individuals with down syndrome (ds) (zhu, j.l., et al, 2013). |
2022-05-13 |
2023-08-13 |
Not clear |
| Neus Martínez Abadías, Helena Pardina, Luis M Echeverry, María Carmona-Iragui, Xavier Sevillano, Yann Heuzé, Juan Forte. Brain dysmorphologies associated with Alzheimer disease in Down syndrome. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555569. |
down syndrome (ds) is a genetic disorder occurring in 1 out of every 700 to 1,000 live births caused by trisomy of chromosome 21. |
2022-05-13 |
2023-08-13 |
Not clear |
| Neus Martínez Abadías, Sergi Llambrich, Rubèn González, Julia M Albaigès, Jens Wouters, Jorge Roldán, Sara Salassa, Vicky Van Bulck, Kaat Wouters, Zsuzsanna Callaerts-Vegh, James Sharpe, Mara Dierssen, Greetje Vande Veld. Dose dependent effects of green tea extracts in the skeletal development of a Down syndrome mouse model. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556856. |
down syndrome (ds) is a congenital disorder caused by trisomy of chromosome 21. |
2022-05-13 |
2023-08-13 |
mouse |
| Anna Kłosowska, Agnieszka Kuchta, Agnieszka Ćwiklińska, Kornelia Sałaga-Zaleska, Maciej Jankowski, Przemysław Kłosowski, Arkadiusz Mański, Michał Zwiefka, Paulina Anikiej-Wiczenbach, Jolanta Wierzb. Relationship between growth and intelligence quotient in children with Down syndrome. Translational pediatrics. vol 11. issue 4. 2022-05-13. PMID:35558976. |
down syndrome (ds) is characterized by short stature, overweight, and cognitive impairment. |
2022-05-13 |
2023-08-13 |
Not clear |
| Nandini Singh, Joan T Richtsmeier, Roger Reeve. Craniofacial morphology of a new mouse model of Down syndrome. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35559460. |
down syndrome (ds) is a complex condition caused by triplication of human chromosome 21 (hsa21). |
2022-05-13 |
2023-08-13 |
mouse |
| b' Neus Mart\\xc3\\xadnez Abad\\xc3\\xadas, Luis Miguel Echeverry, Laura Mar\\xc3\\xa9chal, Sandra M Gim\\xc3\\xa9nez, Xavier M Sevillano, Juan M Fortea, Yann Heuz\\xc3\\xa. Upper airways dysmorphology and obstructive sleeping apnea in Down syndrome. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35559463.' |
down syndrome (ds) is a complex genetic disorder caused by trisomy of chromosome 21 that alters the development of multiple systems, including craniofacial dysmorphologies. |
2022-05-13 |
2023-08-13 |
Not clear |