| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura Esparcia-Pinedo, Ayla Yarci-Carrión, Gloria Mateo-Jiménez, Noelia Ropero, Laura Gómez-Cabañas, Ángel Lancho-Sánchez, Patricia Almendro-Vázquez, Enrique Martín-Gayo, Estela Paz-Artal, Francisco Sanchez-Madrid, Fernando Moldenhauer, Ainhoa Gutiérrez-Cobos, Diego Real de Asúa, Arantzazu Alfranc. Development of an effective immune response in adults with Down Syndrome after SARS-CoV-2 vaccination. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2022-07-23. PMID:35869848. |
immune dysregulation in individuals with down syndrome (ds) leads to an increased risk for hospitalization and death due to covid-19 and may impair the generation of protective immunity after vaccine administration. |
2022-07-23 |
2023-08-14 |
Not clear |
| Aisling Smith, Neidin Bussmann, Colm Breatnach, Philip Levy, Eleanor Molloy, Jan Miletin, Anna Curley, Naomi McCallion, Orla Franklin Mrcpch, Afif El-Khuffas. Serial Assessment of Cardiac Function and Pulmonary Hemodynamics in Infants with Down Syndrome. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 2022-07-22. PMID:35868547. |
there is a dearth of longitudinal data describing the evolution of cardiopulmonary haemodynamics in infants with down syndrome (ds) beyond infancy. |
2022-07-22 |
2023-08-14 |
Not clear |
| Emir Behluli, Nexhibe Nuhii, Thomas Liehr, Gazmend Tema. Suspicions regarding the genetic inheritance of acute lymphoblastic leukemia in patients with down syndrome. Journal of mother and child. 2022-07-19. PMID:35853737. |
children with down syndrome (ds) are at markedly increased risk for acute lymphoblastic leukaemia (all). |
2022-07-19 |
2023-08-14 |
Not clear |
| Heather A Anderson, Melissa D Bailey, Ruth E Manny, Chiu-Yen Ka. Ciliary muscle thickness in adults with Down syndrome. Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists). vol 42. issue 4. 2022-07-16. PMID:35292999. |
the relationship between ciliary muscle thickness (cmt), age and refractive error was investigated to determine if cmt, like other anterior ocular anatomy, differs in adults with down syndrome (ds). |
2022-07-16 |
2023-08-16 |
Not clear |
| Dilys Oladiwura, Yusrah Shweikh, Clare Roberts, Maria Theodoro. Nystagmus in Down Syndrome - a Retrospective Notes Review. The British and Irish orthoptic journal. vol 18. issue 1. 2022-07-15. PMID:35837367. |
nystagmus has been reported in up to 30% of people with down syndrome (ds), and yet is still not well understood. |
2022-07-15 |
2023-08-14 |
Not clear |
| Edward J Evans, James DeGregor. Dissecting stepwise mutational impairment of megakaryopoiesis in a model of Down syndrome-associated leukemia. The Journal of clinical investigation. vol 132. issue 14. 2022-07-15. PMID:35838049. |
individuals with down syndrome (ds) have more than 100-fold increased risk of acute megakaryoblastic leukemia (amkl), but its pathogenesis is poorly understood. |
2022-07-15 |
2023-08-14 |
human |
| Paige Mumford, Justin Tosh, Silvia Anderle, Eleni Gkanatsiou Wikberg, Gloria Lau, Sue Noy, Karen Cleverley, Takashi Saito, Takaomi C Saido, Eugene Yu, Gunnar Brinkmalm, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Victor Tybulewicz, Elizabeth M C Fisher, Frances K Wisema. Genetic mapping of APP and amyloid-β biology modulation by trisomy 21. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-07-14. PMID:35835549. |
individuals who have down syndrome (ds) frequently develop early onset alzheimer's disease (ad), a neurodegenerative condition caused by the build-up of aggregated amyloid-β and tau proteins in the brain. |
2022-07-14 |
2023-08-14 |
Not clear |
| Xiao Sun, Hiroki Kato, Hiroshi Sato, Xu Han, Yuta Hirofuji, Takahiro A Kato, Yasunari Sakai, Shouichi Ohga, Satoshi Fukumoto, Keiji Masud. Dopamine-related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth-derived stem cells of children with Down syndrome. FASEB bioAdvances. vol 4. issue 7. 2022-07-11. PMID:35812076. |
down syndrome (ds) is one of the common genetic disorders caused by the trisomy of human chromosome 21 (hsa21). |
2022-07-11 |
2023-08-14 |
human |
| Carla L Pennella, Tamara Muñoz Cassina, Jorge G Rossi, Edgardo M Baialardo, Patricia Rubio, María A Deu, Luisina Peruzzo, Myriam R Guitter, Cristian G Sanchez de La Rosa, Elizabeth M Alfaro, María S Felic. Clonal Myeloproliferative Disorders in Patients with Down Syndrome-Treatment and Outcome Results from an Institution in Argentina. Cancers. vol 14. issue 13. 2022-07-09. PMID:35805057. |
children with down syndrome (ds) are at an increased risk of developing clonal myeloproliferative disorders. |
2022-07-09 |
2023-08-14 |
Not clear |
| Mengmeng Jin, Ranjie Xu, Le Wang, Mahabub Maraj Alam, Ziyuan Ma, Sining Zhu, Alessandra C Martini, Azadeh Jadali, Matteo Bernabucci, Ping Xie, Kelvin Y Kwan, Zhiping P Pang, Elizabeth Head, Ying Liu, Ronald P Hart, Peng Jian. Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease. Cell stem cell. vol 29. issue 7. 2022-07-08. PMID:35803230. |
down syndrome (ds) is the most common genetic developmental disorder and risk factor for ad. |
2022-07-08 |
2023-08-14 |
mouse |
| Cristina Morsiani, Maria Giulia Bacalini, Salvatore Collura, María Moreno-Villanueva, Nicolle Breusing, Alexander Bürkle, Tilman Grune, Claudio Franceschi, Magda De Eguileor, Miriam Capr. Blood circulating miR-28-5p and let-7d-5p associate with premature ageing in Down Syndrome. Mechanisms of ageing and development. 2022-07-05. PMID:35780970. |
persons with down syndrome (ds) undergo a premature ageing with early onset of age-related diseases. |
2022-07-05 |
2023-08-14 |
human |
| Kirstin A Risgaard, Isabella A Sorci, Sruti Mohan, Anita Bhattacharyy. Meta-Analysis of Down Syndrome Cortical Development Reveals Underdeveloped State of the Science. Frontiers in cellular neuroscience. vol 16. 2022-06-30. PMID:35769326. |
neurodevelopmental impairment contributes to the hallmark cognitive disability in individuals with down syndrome (ds, trisomy 21, t21). |
2022-06-30 |
2023-08-14 |
Not clear |
| Martina Kirstein, Alba Cambrils, Ana Segarra, Ana Melero, Emilio Vare. Cholinergic Senescence in the Ts65Dn Mouse Model for Down Syndrome. Neurochemical research. 2022-06-29. PMID:35767135. |
down syndrome (ds) induces a variable phenotype including intellectual disabilities and early development of alzheimer's disease (ad). |
2022-06-29 |
2023-08-14 |
mouse |
| Maria Martinez de Lagran, Aleix Elizalde-Torrent, Roger Paredes, Bonaventura Clotet, Mara Diersse. Lamivudine, a reverse transcriptase inhibitor, rescues cognitive deficits in a mouse model of down syndrome. Journal of cellular and molecular medicine. 2022-06-28. PMID:35762509. |
down syndrome (ds) is the most common genetic disorder associated with intellectual disability and a genetic form of alzheimer's disease. |
2022-06-28 |
2023-08-14 |
mouse |
| Matheus Negri Boschiero, Camila Vantini Capasso Palamim, Manoela Marques Ortega, Fernando Augusto Lima Marso. Clinical characteristics and comorbidities of COVID-19 in unvaccinated patients with Down syndrome: first year report in Brazil. Human genetics. 2022-06-28. PMID:35763088. |
patients with down syndrome (ds) are more affected by the coronavirus disease (covid)-19 pandemic when compared with other populations. |
2022-06-28 |
2023-08-14 |
Not clear |
| Cheryl B Hines, Staci A Simmon. Down Syndrome: A Review of Key Perioperative Implications. AORN journal. vol 116. issue 1. 2022-06-27. PMID:35758744. |
down syndrome (ds) is the most common chromosomal abnormality in humans that is compatible with life. |
2022-06-27 |
2023-08-14 |
Not clear |
| Cheryl B Hines, Staci A Simmon. Down Syndrome: A Review of Key Perioperative Implications. AORN journal. vol 116. issue 1. 2022-06-27. PMID:35758744. |
down syndrome is associated with numerous comorbidities that can pose challenges for the perioperative nurse caring for a patient with ds undergoing surgery. |
2022-06-27 |
2023-08-14 |
Not clear |
| b' Giacomo Lazzarino, Angela M Amorini, Renata Mangione, Miriam Wissam Saab, Enrico Di Stasio, Michelino Di Rosa, Barbara Tavazzi, Giuseppe Lazzarino, Graziano Onder, Angelo Carf\\xc3\\xa. Biochemical Discrimination of the Down Syndrome-Related Metabolic and Oxidative/Nitrosative Stress Alterations from the Physiologic Age-Related Changes through the Targeted Metabolomic Analysis of Serum. Antioxidants (Basel, Switzerland). vol 11. issue 6. 2022-06-24. PMID:35740106.' |
down syndrome (ds) is a neurodevelopmental disorder that is characterized by an accelerated aging process, frequently associated with the development of alzheimer's disease (ad). |
2022-06-24 |
2023-08-14 |
Not clear |
| Manon Moreau, Maria Carmona-Iragui, Miren Altuna, Lorraine Dalzon, Isabel Barroeta, Marie Vilaire, Sophie Durand, Juan Fortea, Anne-Sophie Rebillat, Nathalie Jane. DYRK1A and Activity-Dependent Neuroprotective Protein Comparative Diagnosis Interest in Cerebrospinal Fluid and Plasma in the Context of Alzheimer-Related Cognitive Impairment in Down Syndrome Patients. Biomedicines. vol 10. issue 6. 2022-06-24. PMID:35740400. |
down syndrome (ds) is a complex genetic condition due to an additional copy of human chromosome 21, which results in the deregulation of many genes. |
2022-06-24 |
2023-08-14 |
mouse |
| Angela John Thurman, Lauren Bullard, Leona Kelly, Caitlyn Wong, Vivian Nguyen, Anna J Esbensen, Jennifer Bekins, Emily K Schworer, Deborah J Fidler, Lisa A Daunhauer, Carolyn B Mervis, C Holley Pitts, Angela M Becerra, Leonard Abbedut. Defining Expressive Language Benchmarks for Children with Down Syndrome. Brain sciences. vol 12. issue 6. 2022-06-24. PMID:35741628. |
establishing expressive language benchmarks (elbs) for children with down syndrome (ds), as developed by tager-flusberg et al. |
2022-06-24 |
2023-08-14 |
human |