| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carolyn F Ross, C B Bernhard, Victoria Surette, Anne Hasted, Ian Wakeling, Sarah Smith-Simpso. Eating behaviours in children with Down syndrome: Results of a home-use test. Journal of texture studies. 2022-06-13. PMID:35696524. |
children with down syndrome (ds) display a disproportionate number of health challenges, including feeding and swallowing difficulties and food texture sensitivities. |
2022-06-13 |
2023-08-14 |
Not clear |
| Yo Hamaguchi, Tatsuro Kondoh, Masafumi Fukuda, Kazumi Yamasaki, Koh-Ichiro Yoshiura, Hiroyuki Moriuchi, Mariko Morii-Kubota, Masashi Muramatsu, Takashi Minami, Motomi Osat. Leukopenia, macrocytosis, and thrombocytopenia occur in young adults with Down syndrome. Gene. 2022-06-11. PMID:35690282. |
down syndrome (ds) is a common congenital disorder caused by trisomy 21. |
2022-06-11 |
2023-08-14 |
Not clear |
| Karan Varshney, Rosemary Iriowen, Kayla Morrell, Preshon Pillay, Alexander Fossi, Mary M Stephen. Disparities and outcomes of patients living with Down Syndrome undergoing healthcare transitions from pediatric to adult care: A scoping review. American journal of medical genetics. Part A. 2022-06-10. PMID:35686676. |
down syndrome (ds) is one of the most common chromosomal disorders worldwide, and people with ds experience more co-morbidities and have poorer health outcomes compared to the general population. |
2022-06-10 |
2023-08-14 |
Not clear |
| Micah K Harris, Richard T Graham, Andréa M Cappellano, Ashley S Margol, George Michaiel, John R Crawford, Myrsini Ioakeim-Ioannidou, Joseph R Stanek, Kevin X Liu, Shannon M MacDonald, Mohamed S Abdelbak. Multi-institutional analysis of central nervous system germ cell tumors in patients with Down syndrome. Pediatric blood & cancer. 2022-06-10. PMID:35686831. |
primary germ cell tumors (gcts) are the most common central nervous system (cns) neoplasm in patients with down syndrome (ds). |
2022-06-10 |
2023-08-14 |
Not clear |
| Zinnat Hasina, Nicole Wang, Chi Chiu Wan. Developmental Neuropathology and Neurodegeneration of Down Syndrome: Current Knowledge in Humans. Frontiers in cell and developmental biology. vol 10. 2022-06-09. PMID:35676933. |
individuals with down syndrome (ds) suffer from developmental delay, intellectual disability, and an early-onset of neurodegeneration, alzheimer's-like disease, or precocious dementia due to an extra chromosome 21. |
2022-06-09 |
2023-08-14 |
Not clear |
| Uma Athale, Rinku Sutradhar, Vicky R Breakey, Qing Li, Mylene Bassal, Paul Gibson, Serina Patel, Laura Wheaton, Jason D Pole, Nicole Mittman, Petros Pechlivanoglou, Sumit Gupt. Healthcare utilization and costs associated with acute lymphoblastic leukemia in children with and without Down syndrome. Pediatric blood & cancer. 2022-06-08. PMID:35674471. |
children with down syndrome (ds) and acute lymphoblastic leukemia (all) are at increased risk of treatment-related morbidity and mortality compared to non-ds-all, requiring increased supportive care. |
2022-06-08 |
2023-08-14 |
Not clear |
| Emma C Utagawa, David G Moreno, Kristian T Schafernak, Nicoleta C Arva, Michael H Malek-Ahmadi, Elliott J Mufson, Sylvia E Pere. Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome. Acta neuropathologica communications. vol 10. issue 1. 2022-06-08. PMID:35676735. |
although down syndrome (ds), the most common developmental genetic cause of intellectual disability, displays proliferation and migration deficits in the prenatal frontal cortex (fc), a knowledge gap exists on the effects of trisomy 21 upon postnatal cortical development. |
2022-06-08 |
2023-08-14 |
Not clear |
| Patrick Lao, Molly E Zimmerman, Sigan L Hartley, José Gutierrez, David Keator, Kay C Igwe, Krystal K Laing, Dejania Cotton-Samuel, Mithra Sathishkumar, Fahmida Moni, Howard Andrews, Sharon Krinsky-McHale, Elizabeth Head, Joseph H Lee, Florence Lai, Michael A Yassa, H Diana Rosas, Wayne Silverman, Ira T Lott, Nicole Schupf, Adam M Brickma. Obstructive sleep apnea, cerebrovascular disease, and amyloid in older adults with Down syndrome across the Alzheimer's continuum. Sleep advances : a journal of the Sleep Research Society. vol 3. issue 1. 2022-06-07. PMID:35669316. |
we determined the extent to which obstructive sleep apnea (osa) is associated with increased cerebrovascular disease and amyloid burden, and the relation of the two processes across clinical alzheimer's disease (ad) diagnostic groups in adults with down syndrome (ds). |
2022-06-07 |
2023-08-14 |
Not clear |
| Patrick Lao, Molly E Zimmerman, Sigan L Hartley, José Gutierrez, David Keator, Kay C Igwe, Krystal K Laing, Dejania Cotton-Samuel, Mithra Sathishkumar, Fahmida Moni, Howard Andrews, Sharon Krinsky-McHale, Elizabeth Head, Joseph H Lee, Florence Lai, Michael A Yassa, H Diana Rosas, Wayne Silverman, Ira T Lott, Nicole Schupf, Adam M Brickma. Obstructive sleep apnea, cerebrovascular disease, and amyloid in older adults with Down syndrome across the Alzheimer's continuum. Sleep advances : a journal of the Sleep Research Society. vol 3. issue 1. 2022-06-07. PMID:35669316. |
adults with ds from the biomarkers of alzheimer's disease in down syndrome (adds) study were included given available research mri ( |
2022-06-07 |
2023-08-14 |
Not clear |
| Keren Xu, Shaobo Li, Ivo S Muskens, Natalina Elliott, Swe Swe Myint, Priyatama Pandey, Helen M Hansen, Libby M Morimoto, Alice Y Kang, Xiaomei Ma, Catherine Metayer, Beth A Mueller, Irene Roberts, Kyle M Walsh, Steve Horvath, Joseph L Wiemels, Adam J de Smit. Accelerated epigenetic aging in newborns with Down syndrome. Aging cell. 2022-06-06. PMID:35661546. |
accelerated aging is a hallmark of down syndrome (ds), with adults experiencing early-onset alzheimer's disease and premature aging of the skin, hair, and immune and endocrine systems. |
2022-06-06 |
2023-08-14 |
Not clear |
| Amélie Coquelet, Anaïck Besozzi, Martine Roussel, Fabienne Lemetaye. Geriatrie et psychologie neuropsychiatrie du vieillissement. vol 20. issue 1. 2022-06-02. PMID:35652846. |
abstract improvement of life expectancy in people with down syndrome (ds) is associated with new problems such as cognitive decline associated with aging and screening/diagnosis for alzheimer's disease (ad) in this population. |
2022-06-02 |
2023-08-14 |
Not clear |
| Leniza G de Castro-Hamoy, Ma-Am Joy R Tumulak, Maria Stephanie Fay S Cagayan, Peter A Sy, Nona Rachel C Mira, Mercy Y Laurin. Attitudes of Filipino parents of children with Down syndrome on noninvasive prenatal testing. Journal of community genetics. 2022-06-02. PMID:35653002. |
this is an exploratory qualitative study that explored the attitudes of filipino parents of children with down syndrome (ds) toward nipt using thematic analysis of in-depth interviews. |
2022-06-02 |
2023-08-14 |
human |
| W Cai, S-S Bae. Effects of 24-week basketball programme on body composition and functional fitness on adults with Down syndrome. Journal of intellectual disability research : JIDR. 2022-06-01. PMID:35642288. |
the body index [body mass, body mass index (bmi), waist circumference and waist-height ratio] and functional fitness (aerobic capacity, muscular strength, balance, flexibility and functional ability) of people with down syndrome (ds) are substantially lower than those in the general population, as ds has an overall negative impact on health. |
2022-06-01 |
2023-08-13 |
Not clear |
| Laura De Rosa, Dominga Fasano, Lucrezia Zerillo, Valeria Valente, Antonella Izzo, Nunzia Mollo, Giuseppina Amodio, Elena Polishchuk, Roman Polishchuk, Mariarosa Anna Beatrice Melone, Chiara Criscuolo, Anna Conti, Lucio Nitsch, Paolo Remondelli, Giovanna Maria Pierantoni, Simona Paladin. Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression. Frontiers in genetics. vol 13. 2022-06-01. PMID:35646085. |
alterations of endosomal compartments were observed in cells from adult individuals with down syndrome (ds), suggesting that the dysfunction of the endosomal pathway may contribute to the pathogenesis of ds. |
2022-06-01 |
2023-08-13 |
human |
| Fiorenza Stagni, Renata Bartesagh. The Challenging Pathway of Treatment for Neurogenesis Impairment in Down Syndrome: Achievements and Perspectives. Frontiers in cellular neuroscience. vol 16. 2022-05-31. PMID:35634470. |
down syndrome (ds), also known as trisomy 21, is a genetic disorder caused by triplication of chromosome 21. |
2022-05-31 |
2023-08-13 |
mouse |
| Nazek Queder, Michael J Phelan, Lisa Taylor, Nicholas Tustison, Eric Doran, Christy Hom, Dana Nguyen, Florence Lai, Margaret Pulsifer, Julie Price, William C Kreisl, Herminia D Rosas, Sharon Krinsky-McHale, Adam M Brickman, Michael A Yassa, Nicole Schupf, Wayne Silverman, Ira T Lott, Elizabeth Head, Mark Mapstone, David B Keato. Joint-label fusion brain atlases for dementia research in Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands). vol 14. issue 1. 2022-05-31. PMID:35634535. |
research suggests a link between alzheimer's disease in down syndrome (ds) and the overproduction of amyloid plaques. |
2022-05-31 |
2023-08-13 |
human |
| Anne Hoffmann, Angela John Thurman, Audra Sterling, Sara T Kover, Lizabeth Finestack, Elizabeth Berry-Kravis, Jamie O Edgin, Andrea Drayton, Eric Fombonne, Leonard Abbedut. Analysis of a Repetitive Language Coding System: Comparisons between Fragile X Syndrome, Autism, and Down Syndrome. Brain sciences. vol 12. issue 5. 2022-05-28. PMID:35624962. |
this study explored how a well-established els protocol can assess three types of linguistic self-repetition in three neurodevelopmental disabilities: fragile x syndrome (fxs), autism spectrum disorder (asd), and down syndrome (ds). |
2022-05-28 |
2023-08-13 |
human |
| Laura Cavalcanti de Oliveira, Daniele de Paula Fari. Pharmacological Approaches to the Treatment of Dementia in Down Syndrome: A Systematic Review of Randomized Clinical Studies. Molecules (Basel, Switzerland). vol 27. issue 10. 2022-05-28. PMID:35630721. |
down syndrome (ds) is considered the most frequent form of intellectual disability, with important expressions of cognitive decline and early dementia. |
2022-05-28 |
2023-08-13 |
Not clear |
| Yathindar Giffin-Rao, Jie Sheng, Bennett Strand, Ke Xu, Leslie Huang, Margaret Medo, Kirstin A Risgaard, Samuel Dantinne, Sruti Mohan, Aratrika Keshan, Roger A Daley, Bradley Levesque, Lindsey Amundson, Rebecca Reese, André M M Sousa, Yunlong Tao, Daifeng Wang, Su-Chun Zhang, Anita Bhattacharyy. Altered patterning of trisomy 21 interneuron progenitors. Stem cell reports. 2022-05-27. PMID:35623352. |
individuals with down syndrome (ds; ts21), the most common genetic cause of intellectual disability, have smaller brains that reflect fewer neurons at pre- and post-natal stages, implicating impaired neurogenesis during development. |
2022-05-27 |
2023-08-13 |
human |
| Bani Bandana Ganguly, Nitin N Kada. Triplication of HSA21 on alterations in structure and function of mitochondria. Mitochondrion. 2022-05-27. PMID:35623559. |
triplication of genes encoded in human chromosome 21 (hsa21) is responsible for the phenotypes of down syndrome (ds). |
2022-05-27 |
2023-08-13 |
human |