| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Ohira, H Ichikawa, E Suzuki, M Iwaki, K Suzuki, F Saito-Ohara, T Ikeuchi, I Chumakov, H Tanahashi, K Tashiro, Y Sakak. A 1.6-Mb P1-based physical map of the Down syndrome region on chromosome 21. Genomics. vol 33. issue 1. 1996-06-13. PMID:8617511. |
the down syndrome (ds) region on chromosome 21, which is responsible for the main features of ds such as characteristic facial features, a congenital heart defect, and mental retardation, has been defined by molecular analysis of ds patients with partial trisomy 21. |
1996-06-13 |
2023-08-12 |
Not clear |
| J W Taub, L H Matherly, M L Stout, S A Buck, J G Gurney, Y Ravindranat. Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia. Blood. vol 87. issue 8. 1996-05-17. PMID:8605357. |
down syndrome (ds) children with acute myeloid leukemia (aml) have significantly higher event-free survival (efs) rates compared with non-ds children when treated with protocols containing 1-beta-d-arabinofuranosylcytosine (ara-c). |
1996-05-17 |
2023-08-12 |
Not clear |
| R V Croce, K H Pitetti, M Horvat, J Mille. Peak torque, average power, and hamstrings/quadriceps ratios in nondisabled adults and adults with mental retardation. Archives of physical medicine and rehabilitation. vol 77. issue 4. 1996-05-17. PMID:8607761. |
to compare isokinetic hamstring and quadriceps peak torque (nm), average power (watts), and corresponding hamstring/quadriceps (hq) ratios (as percentages) of adult men with down syndrome(ds), with mental retardation without down syndrome (nds), and nondisabled sedentary controls (sc). |
1996-05-17 |
2023-08-12 |
Not clear |
| M Shohat, E Akstein, B Davidov, G Barkai, C Legum, M David, H Dar, Y Romem, A Amiel, H Cohe. Amniocentesis rate and the detection of Down syndrome and other chromosomal anomalies in Israel. Prenatal diagnosis. vol 15. issue 10. 1996-03-27. PMID:8587865. |
we investigated the contribution of different screening criteria to the prenatal detection of down syndrome (ds) as well as other chromosomal anomalies in the jewish population in israel during 1990 and 1992. |
1996-03-27 |
2023-08-12 |
Not clear |
| P K Rogan, P Close, J L Blouin, J R Seip, L Gannutz, R L Ladda, S E Antonaraki. Duplication and loss of chromosome 21 in two children with Down syndrome and acute leukemia. American journal of medical genetics. vol 59. issue 2. 1996-03-27. PMID:8588582. |
acute leukemia in down syndrome (ds) is often associated with additional changes in the number or structure of chromosome 21. |
1996-03-27 |
2023-08-12 |
Not clear |
| J P Das, B Divis, J Alexander, R K Parrila, J A Naglier. Cognitive decline due to aging among persons with Down syndrome. Research in developmental disabilities. vol 16. issue 6. 1996-03-15. PMID:8584766. |
this study examined decline in cognitive functions in individuals with down syndrome (ds) over the age of 40 in comparison to participants of the same age and comparable mental handicap without down syndrome (nonds). |
1996-03-15 |
2023-08-12 |
human |
| N J Roizen, T A Blondis, M Irwin, A Rubinoff, J Kieffer, M A Stei. Psychiatric and developmental disorders in families of children with attention-deficit hyperactivity disorder. Archives of pediatrics & adolescent medicine. vol 150. issue 2. 1996-02-28. PMID:8556127. |
to evaluate whether a pediatric family history obtained via a brief parent interview would reveal a high prevalence of psychiatric and developmental disorders in the family members of children with attention-deficit hyperactivity disorder (adhd) compared with a group of children with another chronic developmental disability, down syndrome (ds). |
1996-02-28 |
2023-08-12 |
Not clear |
| B D Ulrich, D A Ulric. Spontaneous leg movements of infants with Down syndrome and nondisabled infants. Child development. vol 66. issue 6. 1996-02-26. PMID:8556903. |
infants with down syndrome (ds) represent a population in which new behaviors are acquired significantly more slowly than in nondisabled infants. |
1996-02-26 |
2023-08-12 |
Not clear |
| G Tchernia, F Lejeune, J F Boccara, M F Denavit, J P Dommergues, F Bernaudi. Erythroblastic and/or megakaryoblastic leukemia in Down syndrome: treatment with low-dose arabinosyl cytosine. Journal of pediatric hematology/oncology. vol 18. issue 1. 1996-02-23. PMID:8556372. |
we report here the clinical response to low-dose arabinosyl cytosine (ara-c) in seven children with down syndrome (ds) and acute leukemia in which blast cells express markers of erythroid and/or megakaryoblastic lineages. |
1996-02-23 |
2023-08-12 |
Not clear |
| H A Drabkin, P Erickso. Down syndrome and leukemia, an update. Progress in clinical and biological research. vol 393. 1996-02-13. PMID:8545449. |
acute leukemia (al) is a relatively uncommon, but dreaded, complication occurring with increased frequency in individuals with down syndrome (ds). |
1996-02-13 |
2023-08-12 |
Not clear |
| N A Bersinger, A Zakher, U Huber, G Pescia, H Schneide. A sensitive enzyme immunoassay for pregnancy-associated plasma protein A (PAPP-A): a possible first trimester method of screening for Down syndrome and other trisomies. Archives of gynecology and obstetrics. vol 256. issue 4. 1996-01-17. PMID:7503590. |
when down syndrome (ds) screening is routinely performed, the level of maternal serum papp-a was found to be within the normal range in pregnancies affected by fetal trisomy 21. |
1996-01-17 |
2023-08-12 |
Not clear |
| M Peled-Kamar, J Lotem, E Okon, L Sachs, Y Grone. Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome. The EMBO journal. vol 14. issue 20. 1995-12-21. PMID:7588627. |
the copper-zinc superoxide dismutase (cuznsod) gene resides on chromosome 21 and is overexpressed in down syndrome (ds) patients. |
1995-12-21 |
2023-08-12 |
mouse |
| D Lucente, H M Chen, D Shea, S N Samec, M Rutter, R Chrast, C Rossier, A Buckler, S E Antonarakis, M K McCormic. Localization of 102 exons to a 2.5 Mb region involved in Down syndrome. Human molecular genetics. vol 4. issue 8. 1995-12-15. PMID:7581367. |
exon amplification has been applied to a 2.5 mb region of chromosome 21 that has been associated with some features of down syndrome (ds). |
1995-12-15 |
2023-08-12 |
Not clear |
| B A Myers, S M Puesche. Major depression in a small group of adults with Down syndrome. Research in developmental disabilities. vol 16. issue 4. 1995-12-06. PMID:7480957. |
the clinical histories and treatment of the nine individuals with down syndrome (ds) and major depression (md) previously noted in a report on the psychopathology of a population of 164 adults with ds with and without health disorders from a down syndrome clinic are presented (myers & pueschel, 1991). |
1995-12-06 |
2023-08-12 |
Not clear |
| R H Reeves, N G Irving, T H Moran, A Wohn, C Kitt, S S Sisodia, C Schmidt, R T Bronson, M T Davisso. A mouse model for Down syndrome exhibits learning and behaviour deficits. Nature genetics. vol 11. issue 2. 1995-11-02. PMID:7550346. |
trisomy 21 or down syndrome (ds) is the most frequent genetic cause of mental retardation, affecting one in 800 live born human beings. |
1995-11-02 |
2023-08-12 |
mouse |
| T Shonk, B D Ros. Role of increased cerebral myo-inositol in the dementia of Down syndrome. Magnetic resonance in medicine. vol 33. issue 6. 1995-09-25. PMID:7651126. |
the purpose of this study was to determine cerebral myo-inositol (mi) in adults with down syndrome (ds), and to trace the chronobiology of ds to alzheimer disease (ad). |
1995-09-25 |
2023-08-12 |
Not clear |
| J Gustafsson, G Annerén, U B Ericsson, L Svanberg, S A Ivarsso. Thyroid antibodies are not a risk factor for pregnancies with Down syndrome. Prenatal diagnosis. vol 15. issue 5. 1995-09-21. PMID:7644435. |
the observation that thyroid disease is frequent in mothers of children with down syndrome (ds) has suggested that maternal thyroid antibodies could be a factor predisposing to trisomy 21 in their offspring. |
1995-09-21 |
2023-08-12 |
Not clear |
| P B Crino, J A Martin, W D Hill, B Greenberg, V M Lee, J Q Trojanowsk. Beta-Amyloid peptide and amyloid precursor proteins in olfactory mucosa of patients with Alzheimer's disease, Parkinson's disease, and Down syndrome. The Annals of otology, rhinology, and laryngology. vol 104. issue 8. 1995-09-13. PMID:7639477. |
dystrophic neurites are present in olfactory epithelium (oe) of patients with alzheimer's disease (ad), parkinson's disease (pd), and down syndrome (ds) and occasionally in normal individuals. |
1995-09-13 |
2023-08-12 |
Not clear |
| A Suzuki, S Takashima, M Mizuguchi, M Kato, T Kunishita, T Tabir. High expression on Kunitz-type protease inhibitor-containing substances in the cerebral vessels of patients with Down syndrome. The Tohoku journal of experimental medicine. vol 174. issue 3. 1995-06-27. PMID:7761983. |
down syndrome (ds) brains, from 19 gestational weeks to 50 years of age were studied by immunohistochemical methods with a polyclonal antibody against synthetic peptide comprising part of the kunitz-type protease inhibitor (kpi) domain of alzheimer disease amyloid precursor protein (app), residues 301 to 323 of app 770. |
1995-06-27 |
2023-08-12 |
Not clear |
| K H Pitetti, S Bone. Cardiovascular fitness as related to leg strength in adults with mental retardation. Medicine and science in sports and exercise. vol 27. issue 3. 1995-06-22. PMID:7752871. |
the purpose of this study was to compare cardiovascular fitness to leg strength of young adults (mean age = 25.2 yr) with mental retardation (mr) with and without down syndrome (ds) and to determine whether a relationship exists. |
1995-06-22 |
2023-08-12 |
human |