| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G B Pozzan, F Rigon, M E Girelli, D Rubello, B Busnardo, C Baccichett. Thyroid function in patients with Down syndrome: preliminary results from non-institutionalized patients in the Veneto region. American journal of medical genetics. Supplement. vol 7. 1991-04-16. PMID:2149975. |
we investigated thyroid function of 108 home-reared down syndrome (ds) patients. |
1991-04-16 |
2023-08-11 |
Not clear |
| G Napolitano, G Palka, S Grimaldi, C Giuliani, G Laglia, G Calabrese, M A Satta, G Neri, F Monac. Growth delay in Down syndrome and zinc sulphate supplementation. American journal of medical genetics. Supplement. vol 7. 1991-04-16. PMID:2149976. |
children affected with down syndrome (ds) show deficient growth, immunodeficiency--especially concerning the t-cell population--and low plasma zinc levels. |
1991-04-16 |
2023-08-11 |
Not clear |
| b' E Piro, C Pennino, M Cammarata, G Corsello, A Grenci, C Lo Giudice, M Morabito, M Piccione, L Giuffr\\xc3\\xa. Growth charts of Down syndrome in Sicily: evaluation of 382 children 0-14 years of age. American journal of medical genetics. Supplement. vol 7. 1991-04-16. PMID:2149977.' |
we present the results of a study performed on a sicilian population of children with down syndrome (ds) 0-14 years of age, observed between 1977 and 1988. |
1991-04-16 |
2023-08-11 |
human |
| M Mikkelsen, H Poulsen, K G Nielse. Incidence, survival, and mortality in Down syndrome in Denmark. American journal of medical genetics. Supplement. vol 7. 1991-04-16. PMID:2149979. |
the incidence of down syndrome (ds) has been studied intensively for the two periods 1960-1972 and 1980-1985. |
1991-04-16 |
2023-08-11 |
Not clear |
| C Stoll, Y Alembik, B Dott, M P Rot. Epidemiology of Down syndrome in 118,265 consecutive births. American journal of medical genetics. Supplement. vol 7. 1991-04-16. PMID:2149980. |
the epidemiology of down syndrome (ds) was studied in the area which is covered by our registry of congenital malformations. |
1991-04-16 |
2023-08-11 |
Not clear |
| C Baccichetti, E Lenzini, R Pegorar. Down syndrome in the Belluno district (Veneto region, northeast Italy): age distribution and morbidity. American journal of medical genetics. Supplement. vol 7. 1991-04-16. PMID:2149981. |
a structured pre-planned form was used to collect data on age distribution and morbidity of down syndrome (ds). |
1991-04-16 |
2023-08-11 |
Not clear |
| J R Korenberg, H Kawashima, S M Pulst, L Allen, E Magenis, C J Epstei. Down syndrome: toward a molecular definition of the phenotype. American journal of medical genetics. Supplement. vol 7. 1991-04-16. PMID:2149983. |
down syndrome (ds) is a major cause of mental retardation and heart disease. |
1991-04-16 |
2023-08-11 |
Not clear |
| M S Krawczun, E C Jenkins, K P Lele, E A Sersen, H M Wisniewsk. Study of spindle microtubule reassembly in cells from Alzheimer and Down syndrome patients following exposure to colcemid. Alzheimer disease and associated disorders. vol 4. issue 4. 1991-02-14. PMID:2148262. |
numerous intraneuronal neurofibrillary tangles and senile (neuritic) plaques are the two characteristic lesions in alzheimer disease (ad) and adult down syndrome (ds). |
1991-02-14 |
2023-08-11 |
Not clear |
| C Caltagirone, U Nocentini, S Vicar. Cognitive functions in adult Down's syndrome. The International journal of neuroscience. vol 54. issue 3-4. 1991-02-12. PMID:2148315. |
cognitive profiles of performances were obtained from a selected group of adult down syndrome (ds) subjects (n = 20; mean age: 34.5 years; s.d. |
1991-02-12 |
2023-08-11 |
human |
| P Mathew, D Moodie, R Sterba, D Murphy, E Rosenkranz, A Hom. Long-term follow-up of children with Down syndrome with cardiac lesions. Clinical pediatrics. vol 29. issue 10. 1991-01-24. PMID:2147603. |
two hundred and eighty four patients with down syndrome (ds) were seen between 1951-1989. |
1991-01-24 |
2023-08-11 |
Not clear |
| E Antila, U R Nordberg, E L Syväoja, T Westermarc. Selenium therapy in Down syndrome (DS): a theory and a clinical trial. Advances in experimental medicine and biology. vol 264. 1990-12-31. PMID:2147090. |
selenium therapy in down syndrome (ds): a theory and a clinical trial. |
1990-12-31 |
2023-08-11 |
Not clear |
| E Petrocik, E R Wassman, J J Lee, J C Kell. Second trimester maternal serum pregnancy specific beta-1 glycoprotein (SP-1) levels in normal and Down syndrome pregnancies. American journal of medical genetics. vol 37. issue 1. 1990-12-05. PMID:2146876. |
maternal serum pregnancy specific beta-1 glycoprotein (sp-1) levels in the second trimester may be predictive of down syndrome (ds). |
1990-12-05 |
2023-08-11 |
human |
| A Marks, R Allor. S100 protein and Down syndrome. BioEssays : news and reviews in molecular, cellular and developmental biology. vol 12. issue 8. 1990-12-05. PMID:2146955. |
the gene for s100 protein has been mapped to the 21q22 region, a chromosomal locus whose duplication has been implicated in the generation of down syndrome (ds). |
1990-12-05 |
2023-08-11 |
Not clear |
| O S Jørgensen, B W Brooksbank, R Baláz. Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease. Journal of the neurological sciences. vol 98. issue 1. 1990-12-04. PMID:1977892. |
proteins relatively enriched in neurons (neural cell adhesion molecule (ncam) and d3-protein) or in glia (glutamine synthetase, glial fibrillary acidic protein (gfap) and s100) were measured by quantitative immunochemical methods in autopsy samples of the cerebral cortex of subjects with alzheimer disease (ad) and adults with down syndrome (ds), the latter also presenting manifest signs of alzheimer type of neuropathology. |
1990-12-04 |
2023-08-11 |
human |
| M LeMay, N Alvare. The relationship between enlargement of the temporal horns of the lateral ventricles and dementia in aging patients with Down syndrome. Neuroradiology. vol 32. issue 2. 1990-10-12. PMID:2144615. |
down syndrome (ds) results from the inheritance of three chromosomes 21, and it has been shown that after the age of 35 the brains of patients with ds commonly show neuropathological changes similar to those in patients with ad. |
1990-10-12 |
2023-08-11 |
Not clear |
| J R Korenberg, H Kawashima, S M Pulst, T Ikeuchi, N Ogasawara, K Yamamoto, S A Schonberg, R West, L Allen, E Mageni. Molecular definition of a region of chromosome 21 that causes features of the Down syndrome phenotype. American journal of human genetics. vol 47. issue 2. 1990-09-04. PMID:2143053. |
down syndrome (ds) is a major cause of mental retardation and heart disease. |
1990-09-04 |
2023-08-11 |
Not clear |
| P L Barnett, A C Clark, O M Garso. Acute nonlymphocytic leukemia after transient myeloproliferative disorder in a patient with Down syndrome. Medical and pediatric oncology. vol 18. issue 5. 1990-08-24. PMID:2142749. |
an infant with down syndrome (ds) and rh isoimmunization developed transient myeloproliferative disorder (tmd) during the neonatal period. |
1990-08-24 |
2023-08-11 |
Not clear |
| R Guerrini, P Genton, M Bureau, C Dravet, J Roge. Reflex seizures are frequent in patients with Down syndrome and epilepsy. Epilepsia. vol 31. issue 4. 1990-08-21. PMID:2142449. |
in a retrospective study of 30 down syndrome (ds) patients with epilepsy, we found 6 cases (20%) with reflex seizures. |
1990-08-21 |
2023-08-11 |
Not clear |
| M E Percy, A J Dalton, V D Markovic, D R Crapper McLachlan, E Gera, J T Hummel, A C Rusk, M J Somerville, D F Andrews, P G Walfis. Autoimmune thyroiditis associated with mild "subclinical" hypothyroidism in adults with Down syndrome: a comparison of patients with and without manifestations of Alzheimer disease. American journal of medical genetics. vol 36. issue 2. 1990-08-13. PMID:2142381. |
serum tests of thyroid function were compared in down syndrome (ds) patients with and without manifestations of alzheimer disease (ad). |
1990-08-13 |
2023-08-11 |
Not clear |
| Y Groner, O Elroy-Stein, K B Avraham, R Yarom, M Schickler, H Knobler, G Rotma. Down syndrome clinical symptoms are manifested in transfected cells and transgenic mice overexpressing the human Cu/Zn-superoxide dismutase gene. Journal de physiologie. vol 84. issue 1. 1990-08-02. PMID:1972759. |
down syndrome (ds), the phenotypic expression of human trisomy 21, is presumed to result from overexpression of certain genes residing on chromosome 21 at the segment 21q22-the down locus. |
1990-08-02 |
2023-08-11 |
mouse |