| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Murphy, H M C V Hoey, M Philip, E F Roche, S Macken, P Mayne, D Duff, M O'Keefe, D McShane, E Fogarty, M O'Rega. Guidelines for the medical management of Irish children and adolescents with Down syndrome. Irish medical journal. vol 98. issue 2. 2005-05-26. PMID:15835512. |
down syndrome (ds) is the most common chromosomal cause of developmental disability in ireland. |
2005-05-26 |
2023-08-12 |
Not clear |
| John M Graham, Beth Rosner, Elisabeth Dykens, Jeannie Visootsa. Behavioral features of CHARGE syndrome (Hall-Hittner syndrome) comparison with Down syndrome, Prader-Willi syndrome, and Williams syndrome. American journal of medical genetics. Part A. vol 133A. issue 3. 2005-05-24. PMID:15637708. |
we conducted behavioral and personality assessments in 14 boys with hhs syndrome aged 6-21 years, and compared their characteristics with similar data from 20 age-matched boys with down syndrome (ds), 17 boys with prader-willi syndrome (pws), and 16 boys with williams syndrome (ws). |
2005-05-24 |
2023-08-12 |
Not clear |
| Alexander M Kleschevnikov, Pavel V Belichenko, Angela J Villar, Charles J Epstein, Robert C Malenka, William C Moble. Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 37. 2005-05-17. PMID:15371516. |
down syndrome (ds), a disorder caused by the presence of three copies of chromosome 21 (trisomy 21), is characterized by impairments in learning and memory attributable to dysfunction of the hippocampus. |
2005-05-17 |
2023-08-12 |
mouse |
| Rosa Ferrando Miguel, Arnold Pollak, Gert Lube. Metalloproteinase ADAMTS-1 but not ADAMTS-5 is manifold overexpressed in neurodegenerative disorders as Down syndrome, Alzheimer's and Pick's disease. Brain research. Molecular brain research. vol 133. issue 1. 2005-05-12. PMID:15661359. |
as the gene for this protein is encoded on chromosome 21 and maybe overexpressed due to the gene dosage hypothesis based upon the presence of a third chromosome in trisomy 21, we decided to study expression in down syndrome (ds) brain and used brains of patients with alzheimer's (ad) and pick's disease (pd) as controls. |
2005-05-12 |
2023-08-12 |
mouse |
| Bo Fernhall, Arturo Figueroa, Scott Collier, Tracy Baynard, Ifigenia Giannopoulou, Styliani Goulopoulo. Blunted heart rate response to upright tilt in people with Down syndrome. Archives of physical medicine and rehabilitation. vol 86. issue 4. 2005-05-12. PMID:15827937. |
to determine whether heart rate and blood pressure responses to upright tilt would be lower in subjects with down syndrome (ds) than in control subjects with no disabilities. |
2005-05-12 |
2023-08-12 |
human |
| Ken-Ichiro Kobayashi, Ikuya Usami, Masaru Kubota, Toshikazu Nishio, Naoki Kakaz. Chromosome 7 abnormalities in acute megakaryoblastic leukemia associated with Down syndrome. Cancer genetics and cytogenetics. vol 158. issue 2. 2005-05-09. PMID:15796967. |
a 2-year-old girl with down syndrome (ds) developed acute megakaryoblastic leukemia (amkl) following a transient myeloproliferative disorder (tmd). |
2005-05-09 |
2023-08-12 |
Not clear |
| Erica Prussing, Elisa J Sobo, Elizabeth Walker, Paul S Kurti. Between 'desperation' and disability rights: a narrative analysis of complementary/alternative medicine use by parents for children with Down syndrome. Social science & medicine (1982). vol 60. issue 3. 2005-04-29. PMID:15550306. |
this paper presents a narrative analysis of complementary/alternative medicine (cam) use by parents for children with down syndrome (ds), based on interviews conducted with thirty families. |
2005-04-29 |
2023-08-12 |
human |
| S Giannone, P Strippoli, L Vitale, R Casadei, S Canaider, L Lenzi, P D'Addabbo, F Frabetti, F Facchin, A Farina, P Carinci, M Zannott. Gene expression profile analysis in human T lymphocytes from patients with Down Syndrome. Annals of human genetics. vol 68. issue Pt 6. 2005-04-26. PMID:15598213. |
down syndrome (ds) is caused by the presence of three copies of the whole human chromosome 21 (hc21) or of a hc21 restricted region; the phenotype is likely to have originated from the altered expression of genes in the hc21. |
2005-04-26 |
2023-08-12 |
human |
| Jennie Laigaard, Michael Christiansen, Camilla Fröhlich, Bent Nøorgaard Pedersen, Bent Ottesen, Ulla M Wewe. The level of ADAM12-S in maternal serum is an early first-trimester marker of fetal trisomy 18. Prenatal diagnosis. vol 25. issue 1. 2005-04-26. PMID:15662668. |
recently, maternal serum levels of adam12-s were found to be markedly reduced during the first trimester of pregnancies with a down syndrome (ds) fetus. |
2005-04-26 |
2023-08-12 |
human |
| Brian Skotk. Mothers of children with Down syndrome reflect on their postnatal support. Pediatrics. vol 115. issue 1. 2005-04-19. PMID:15629983. |
since 1964, researchers have been examining the ways in which physicians deliver a postnatal diagnosis of down syndrome (ds). |
2005-04-19 |
2023-08-12 |
Not clear |
| Ralph A Nixo. Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases. Neurobiology of aging. vol 26. issue 3. 2005-04-19. PMID:15639316. |
in alzheimer's disease (ad), endosome abnormalities are among the earliest neuropathologic features to develop and have now been closely linked to genetic risk factors for ad, including app triplication in trisomy 21 (down syndrome, ds) and apoe4 genotype in sporadic ad. |
2005-04-19 |
2023-08-12 |
Not clear |
| Ira T Lott, Elizabeth Hea. Alzheimer disease and Down syndrome: factors in pathogenesis. Neurobiology of aging. vol 26. issue 3. 2005-04-19. PMID:15639317. |
in down syndrome (ds) all adults over the age of 40 years develop sufficient neuropathology for a diagnosis of ad. |
2005-04-19 |
2023-08-12 |
Not clear |
| Bernward Zeller, Göran Gustafsson, Erik Forestier, Jonas Abrahamsson, Niels Clausen, Jesper Heldrup, Liisa Hovi, Gudmundur Jonmundsson, Sverre O Lie, Anders Glomstein, Henrik Hasl. Acute leukaemia in children with Down syndrome: a population-based Nordic study. British journal of haematology. vol 128. issue 6. 2005-04-19. PMID:15755283. |
to determine the epidemiology and outcome of children with down syndrome (ds) diagnosed with acute leukaemia in the nordic countries, data registered in the nordic society of paediatric haematology and oncology (nopho) population-based leukaemia registry were analysed. |
2005-04-19 |
2023-08-12 |
Not clear |
| T N Takahashi, J E Farmer, K K Deidrick, B S Hsu, J H Miles, B L Mari. Joubert syndrome is not a cause of classical autism. American journal of medical genetics. Part A. vol 132A. issue 4. 2005-04-18. PMID:15633174. |
rates of family loading for neuropsychiatric disorders in the js families were compared to autism family history data and down syndrome (ds) controls. |
2005-04-18 |
2023-08-12 |
human |
| Kristen L O'Neill, Justine Shults, Virginia A Stallings, Nicolas Stettle. Child-feeding practices in children with down syndrome and their siblings. The Journal of pediatrics. vol 146. issue 2. 2005-04-18. PMID:15689916. |
to compare parental feeding practices and evaluate their relationship to weight status among children with down syndrome (ds) and their unaffected siblings. |
2005-04-18 |
2023-08-12 |
Not clear |
| Marília de Arruda Cardoso Smith, Bianca Borsatto-Galera, Roger Israel Feller, Alaíde Gonçalves, Rosa Sayoto Kawasaki Oyama, Rosemeire Segato, Elizabeth Chen, Gianna Maria Griz Carvalheira, Antonio Santos Clemente Filho, Rommel Rodríguez Burbano, Spencer Luiz Marques Payã. Telomeres on chromosome 21 and aging in lymphocytes and gingival fibroblasts from individuals with Down syndrome. Journal of oral science. vol 46. issue 3. 2005-04-08. PMID:15508750. |
progressive chromosome 21 loss in individuals with trisomy 21 or down syndrome (ds) is supposedly related to their premature senescence. |
2005-04-08 |
2023-08-12 |
human |
| M V A Singh, C Richards, J C Bowe. Does Down syndrome affect the outcome of congenital duodenal obstruction? Pediatric surgery international. vol 20. issue 8. 2005-04-05. PMID:15309469. |
congenital duodenal obstruction (do) has a well-known association with down syndrome (ds) and other congenital malformations. |
2005-04-05 |
2023-08-12 |
Not clear |
| Jouni Vesa, Ying Brown, Danielle Greenfield, Julie R Korenber. Molecular and cellular characterization of the Down syndrome critical region protein 2. Biochemical and biophysical research communications. vol 328. issue 1. 2005-03-28. PMID:15670775. |
down syndrome (ds) is caused by trisomy for human chromosome 21 and is the most common genetic cause of mental retardation. |
2005-03-28 |
2023-08-12 |
human |
| Beverly D Ulrich, Victoria Haehl, Ugo H Buzzi, Masayoshi Kubo, Kenneth G Hol. Modeling dynamic resource utilization in populations with unique constraints: preadolescents with and without Down syndrome. Human movement science. vol 23. issue 2. 2005-03-16. PMID:15474174. |
in this study we used a damped inverted pendulum and spring with an escapement function model to compare the global levels of stiffness and forcing used by 12 preadolescents with down syndrome (ds) and 12 with typical development (td). |
2005-03-16 |
2023-08-12 |
human |
| R Ferrando-Miguel, M S Cheon, G Lube. Protein levels of genes encoded on chromosome 21 in fetal Down Syndrome brain (Part V): overexpression of phosphatidyl-inositol-glycan class P protein (DSCR5). Amino acids. vol 26. issue 3. 2005-03-15. PMID:15221505. |
down syndrome (ds, trisomy 21) is the most common genetic cause of mental retardation. |
2005-03-15 |
2023-08-12 |
Not clear |