| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Santosh Sinh. Anti-oxidant gene expression imbalance, aging and Down syndrome. Life sciences. vol 76. issue 12. 2005-03-08. PMID:15670619. |
the expression of copper zinc superoxide dismutase (sod1), manganese superoxide dismutase (sod2), glutathione peroxidase (gpx), and catalase (cat) genes have been detected in human skin fibroblast cells for 2 year normal child (control), 50 year old normal male and female and a 1 year old down syndrome (ds) male and female with established trisomy karyotype using the rt-pcr technique. |
2005-03-08 |
2023-08-12 |
human |
| Janusz Frackowiak, Anna Potempska, Harry LeVine, Taraneh Haske, Dennis Dickson, Bozena Mazur-Koleck. Extracellular deposits of A beta produced in cultures of Alzheimer disease brain vascular smooth muscle cells. Journal of neuropathology and experimental neurology. vol 64. issue 1. 2005-03-03. PMID:15715088. |
alzheimer disease (ad) and down syndrome (ds) brains contain deposits of amyloid-beta peptide that are located extracellularly in the neuropil and in blood vessels walls. |
2005-03-03 |
2023-08-12 |
Not clear |
| Thomas G Hampton, Melissa R Stasko, Ajit Kale, Ivo Amende, Alberto C S Cost. Gait dynamics in trisomic mice: quantitative neurological traits of Down syndrome. Physiology & behavior. vol 82. issue 2-3. 2005-02-17. PMID:15276802. |
the segmentally trisomic mouse ts65dn is a model of down syndrome (ds). |
2005-02-17 |
2023-08-12 |
mouse |
| Kenji Amano, Haruhiko Sago, Chiharu Uchikawa, Taishi Suzuki, Svetlana E Kotliarova, Nobuyuki Nukina, Charles J Epstein, Kazuhiro Yamakaw. Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome. Human molecular genetics. vol 13. issue 13. 2005-02-16. PMID:15138197. |
down syndrome (ds) is the most common chromosomally caused form of mental retardation and is caused by trisomy of chromosome 21. |
2005-02-16 |
2023-08-12 |
mouse |
| b' Tomislav Skrinjari\\xc4\\x87, Domagoj Glavina, Jelka Juki\\xc4\\x8. Palatal and dental arch morphology in Down syndrome. Collegium antropologicum. vol 28. issue 2. 2005-02-09. PMID:15666619.' |
the analysis of palatal vault morphology and maxillary dental arch shape was carried out in the sample of 42 down syndrome (ds) patients with trisomy 21. |
2005-02-09 |
2023-08-12 |
human |
| Stefano Vicari, Elisabeth Bates, Maria Cristina Caselli, Patrizio Pasqualetti, Chiara Gagliardi, Francesca Tonucci, Virginia Volterr. Neuropsychological profile of Italians with Williams syndrome: an example of a dissociation between language and cognition? Journal of the International Neuropsychological Society : JINS. vol 10. issue 6. 2005-02-04. PMID:15637777. |
important claims have been made regarding the contrasting profiles of linguistic and cognitive performance observed in two genetically based syndromes, williams syndrome (ws) and down syndrome (ds). |
2005-02-04 |
2023-08-12 |
human |
| K N Canfield, L G Spector, L L Robison, D Lazovich, M Roesler, A F Olshan, F O Smith, N A Heerema, D R Barnard, C K Blair, J A Ros. Childhood and maternal infections and risk of acute leukaemia in children with Down syndrome: a report from the Children's Oncology Group. British journal of cancer. vol 91. issue 11. 2005-02-03. PMID:15520821. |
children with down syndrome (ds) are highly susceptible to acute leukaemia. |
2005-02-03 |
2023-08-12 |
Not clear |
| M Clementi, S Bianca, F Benedicenti, R Tencon. Down syndrome and parity. Community genetics. vol 2. issue 1. 2005-01-28. PMID:15178957. |
to investigate the effect of parity on down syndrome (ds). |
2005-01-28 |
2023-08-12 |
Not clear |
| Olivier Menzel, Tibor Vellai, Krisztina Takacs-Vellai, Alexandre Reymond, Fritz Mueller, Stylianos E Antonarakis, Michel Guippon. The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development. Genomics. vol 84. issue 2. 2005-01-28. PMID:15233996. |
down syndrome (ds), as a phenotypic result of trisomy 21, is the most frequent aneuploidy at birth and the most common known genetic cause of mental retardation. |
2005-01-28 |
2023-08-12 |
human |
| Lawrence M Borland, Jacqueline Colligan, Barbara W Brando. Frequency of anesthesia-related complications in children with Down syndrome under general anesthesia for noncardiac procedures. Paediatric anaesthesia. vol 14. issue 9. 2005-01-26. PMID:15330954. |
craniofacial and cardiac anomalies of down syndrome (ds; trisomy 21) would seem to place these patients at higher risk of anesthesia-related complications (arcs), but to date no comprehensive large-scale study has quantified this risk. |
2005-01-26 |
2023-08-12 |
Not clear |
| M Kadota, R Nishigaki, C C Wang, T Toda, Y Shirayoshi, T Inoue, T Gojobori, K Ikeo, M S Rogers, M Oshimur. Proteomic signatures and aberrations of mouse embryonic stem cells containing a single human chromosome 21 in neuronal differentiation: an in vitro model of Down syndrome. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501590. |
neurodegeneration in fetal development of down syndrome (ds) patients is proposed to result in apparent neuropathological abnormalities and to contribute to the phenotypic characteristics of mental retardation and premature development of alzheimer disease. |
2005-01-13 |
2023-08-12 |
mouse |
| R Benavides-Piccione, I Ballesteros-Yáñez, M Martínez de Lagrán, G Elston, X Estivill, C Fillat, J Defelipe, M Diersse. On dendrites in Down syndrome and DS murine models: a spiny way to learn. Progress in neurobiology. vol 74. issue 2. 2005-01-11. PMID:15518956. |
on dendrites in down syndrome and ds murine models: a spiny way to learn. |
2005-01-11 |
2023-08-12 |
human |
| Jie Hu, Sofia Shekhter-Levin, Peter H Shaw, Carolyn Bay, Sally Kochmar, Urvashi Surt. A case of myelodysplastic syndrome with acquired monosomy 7 in a child with a constitutional t(1;19) and a mosaicism for trisomy 21. Cancer genetics and cytogenetics. vol 156. issue 1. 2005-01-11. PMID:15588858. |
because acute myelogenous leukemia (aml) and mds with down syndrome (ds) have distinct biologic and clinical features, the identification of ds patients with a mild or normal phenotype in the aml/mds population is of fundamental importance for clinical diagnosis and management. |
2005-01-11 |
2023-08-12 |
Not clear |
| Mylène Bassal, Mei K La, James A Whitlock, Harland N Sather, Nyla A Heerema, Paul S Gaynon, Linda C Stor. Lymphoblast biology and outcome among children with Down syndrome and ALL treated on CCG-1952. Pediatric blood & cancer. vol 44. issue 1. 2005-01-04. PMID:15368546. |
patients with down syndrome (ds) and standard risk (sr) acute lymphoblastic leukemia (all-ds) are reported to have inferior event free (efs) and overall survival (os) compared to patients without ds (all-nds). |
2005-01-04 |
2023-08-12 |
Not clear |
| Jeffrey W Taub, Yubin G. Down syndrome, drug metabolism and chromosome 21. Pediatric blood & cancer. vol 44. issue 1. 2005-01-04. PMID:15390307. |
this is best exemplified in cases of children with down syndrome (ds), who have significantly higher risks of developing leukemia compared to non-ds children and distinctive treatment outcomes, particularly in cases of acute myeloid leukemia (aml). |
2005-01-04 |
2023-08-12 |
Not clear |
| Alan S Gami. Acute myeloid leukemia and Down syndrome evolution of modern therapy--state of the art review. Pediatric blood & cancer. vol 44. issue 1. 2005-01-04. PMID:15534881. |
over the past decade, a series of clinical reports have described the experience of down syndrome (ds) children treated for acute myeloid leukemia (aml). |
2005-01-04 |
2023-08-12 |
Not clear |
| Gita V Masse. Transient leukemia in newborns with Down syndrome. Pediatric blood & cancer. vol 44. issue 1. 2005-01-04. PMID:15558701. |
children with down syndrome (ds) have a 10- to 20-fold increased risk of developing leukemia, particularly acute megakaryocytic leukemia. |
2005-01-04 |
2023-08-12 |
human |
| L E Olson, R J Roper, L L Baxter, E J Carlson, C J Epstein, R H Reeve. Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes. Developmental dynamics : an official publication of the American Association of Anatomists. vol 230. issue 3. 2004-12-30. PMID:15188443. |
two mouse models are widely used for down syndrome (ds) research. |
2004-12-30 |
2023-08-12 |
mouse |
| Melissa Sliger, Timothy Lander, Claire Murph. Effects of the ApoE epsilon4 allele on olfactory function in Down syndrome. Journal of Alzheimer's disease : JAD. vol 6. issue 4. 2004-12-30. PMID:15345810. |
the present study investigated the effects of the apolipoprotein e (apoe) epsilon4 allele, a risk factor for alzheimer's disease (ad), on olfactory function in down syndrome (ds). |
2004-12-30 |
2023-08-12 |
human |
| Erica Prussing, Elisa J Sobo, Elizabeth Walker, Kimberly Dennis, Paul S Kurti. Communicating with pediatricians about complementary/alternative medicine: perspectives from parents of children with down syndrome. Ambulatory pediatrics : the official journal of the Ambulatory Pediatric Association. vol 4. issue 6. 2004-12-30. PMID:15548099. |
this pilot study of parents of children with down syndrome (ds) used qualitative methods to explore parents' perceptions of the extent and quality of communication about cam with pediatricians, to elicit parents' recommendations for improvement, and to formulate new research questions. |
2004-12-30 |
2023-08-12 |
Not clear |