| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ferdinando Iellamo, Alberto Galante, Jacopo M Legramante, Maria Enrichetta Lippi, Claudia Condoluci, Giorgio Albertini, Maurizio Volterran. Altered autonomic cardiac regulation in individuals with Down syndrome. American journal of physiology. Heart and circulatory physiology. vol 289. issue 6. 2006-01-10. PMID:16024564. |
ten subjects with down syndrome (ds) and ten gender-and age-matched healthy control subjects were studied at rest and during active orthostatism, which induces reciprocal changes in sympathetic and parasympathetic traffic to the heart. |
2006-01-10 |
2023-08-12 |
human |
| Ron Maymon, Orna Levinsohn-Tavor, Howard Cuckle, Yosef Tovbin, Eli Dreazen, Yifat Wiener, Arie Herma. Second trimester ultrasound prenasal thickness combined with nasal bone length: a new method of Down syndrome screening. Prenatal diagnosis. vol 25. issue 10. 2006-01-06. PMID:16088862. |
to evaluate ultrasound prenasal thickness (pt) as a way of enhancing the down syndrome (ds) screening performance of second-trimester nasal bone (nb) length measurement. |
2006-01-06 |
2023-08-12 |
Not clear |
| James A Whitlock, Harland N Sather, Paul Gaynon, Leslie L Robison, Robert J Wells, Michael Trigg, Nyla A Heerema, Smita Bhati. Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study. Blood. vol 106. issue 13. 2006-01-06. PMID:16109782. |
we assessed the outcome of children with down syndrome (ds) and acute lymphoblastic leukemia (all) receiving contemporary risk-based therapy by evaluating clinical and biologic features and outcome of children with all, with or without ds, enrolled in children's cancer group (ccg) protocols between 1983 and 1995. |
2006-01-06 |
2023-08-12 |
Not clear |
| Anshu Awasthi, Reena Das, Neelam Varma, Jasmina Ahluwalia, Anju Gupta, R K Marwaha, Gurjeewan Garewa. Hematological disorders in Down syndrome: ten-year experience at a Tertiary Care Centre in North India. Pediatric hematology and oncology. vol 22. issue 6. 2006-01-03. PMID:16169817. |
a total of 239 cases of down syndrome (ds) were seen in the genetic clinic between 1992 and 2003, of which of 15 had hematological manifestations at presentation. |
2006-01-03 |
2023-08-12 |
Not clear |
| Ron Maymon, Ortal Neeman, Adrian Shulman, Hadar Rosen, Arie Herma. Current concepts of Down syndrome screening tests in assisted reproduction twin pregnancies: another double trouble. Prenatal diagnosis. vol 25. issue 9. 2005-12-29. PMID:16170837. |
various methods of screening for down syndrome (ds) were introduced in clinical practice during the last two decades, and specific problems were encountered when they were applied for twin pregnancies. |
2005-12-29 |
2023-08-12 |
human |
| Felix Beacher, Andy Simmons, Eileen Daly, Verinder Prasher, Claire Adams, Maria Luisa Margallo-Lana, Robin Morris, Simon Lovestone, Kieran Murphy, Declan G M Murph. Hippocampal myo-inositol and cognitive ability in adults with Down syndrome: an in vivo proton magnetic resonance spectroscopy study. Archives of general psychiatry. vol 62. issue 12. 2005-12-27. PMID:16330724. |
down syndrome (ds) is the most common genetic cause of mental retardation. |
2005-12-27 |
2023-08-12 |
Not clear |
| Karin M Fuchs, Jeffrey F Peiper. First trimester Down syndrome screening: public health implications. Seminars in perinatology. vol 29. issue 4. 2005-12-22. PMID:16104680. |
down syndrome (ds) screening has been an integral part of routine prenatal screening for the last three decades. |
2005-12-22 |
2023-08-12 |
Not clear |
| Warren B Zigman, Edmund C Jenkins, Benjamin Tycko, Nicole Schupf, Wayne Silverma. Mortality is associated with apolipoprotein E epsilon4 in nondemented adults with Down syndrome. Neuroscience letters. vol 390. issue 2. 2005-12-15. PMID:16122874. |
previous studies of adults with down syndrome (ds) have consistently found that the presence of the apolipoprotein e epsilon2 allele increases longevity and reduces the risk of dementia, while the apolipoprotein e epsilon4 allele increases risk for dementia. |
2005-12-15 |
2023-08-12 |
Not clear |
| J L Gair, L Arbour, R Rupps, R Jiang, H Bruyère, W P Robinso. Recurrent trisomy 21: four cases in three generations. Clinical genetics. vol 68. issue 5. 2005-12-13. PMID:16207210. |
we present an unusual pedigree with four cases of down syndrome (ds) with free t21 were born to four separate women related through three generations of one family. |
2005-12-13 |
2023-08-12 |
Not clear |
| Sharon R Pine, Qianxu Guo, Changhong Yin, Somasundaram Jayabose, Oya Levendoglu-Tugal, M Fevzi Ozkaynak, Claudio Sandova. GATA1 as a new target to detect minimal residual disease in both transient leukemia and megakaryoblastic leukemia of Down syndrome. Leukemia research. vol 29. issue 11. 2005-12-02. PMID:15916804. |
acquired mutations in exon 2 of the gata1 gene are detected in most down syndrome (ds) patients with transient leukemia (tl) and acute megakaryoblastic leukemia (amkl). |
2005-12-02 |
2023-08-12 |
Not clear |
| Adán Valladares, Virginia Palma-Padilla, Juan Manuel Mejía-Aranguré, Roberto Guevara-Yánez, Azucena Lerma-Reyes, Fabio Salamanca-Góme. Cytogenetic studies in children with Down syndrome and acute leukemia. Leukemia research. vol 29. issue 11. 2005-12-02. PMID:16164980. |
the frequency of chromosomal alterations was compared among four children groups: those with down syndrome and acute leukemia (ds/al), those with acute leukemia (al), those with only down syndrome (ds) and healthy children (nc). |
2005-12-02 |
2023-08-12 |
Not clear |
| C Langebrake, U Creutzig, D Reinhard. Immunophenotype of Down syndrome acute myeloid leukemia and transient myeloproliferative disease differs significantly from other diseases with morphologically identical or similar blasts. Klinische Padiatrie. vol 217. issue 3. 2005-11-30. PMID:15858703. |
children with down syndrome (ds) have a 20-40 fold increased risk of developing acute myeloid leukemia (aml), mainly of the megakaryoblastic subtype (amkl). |
2005-11-30 |
2023-08-12 |
Not clear |
| Richard J Siarey, Angela J Villar, Charles J Epstein, Zygmunt Galdzick. Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome. Neuropharmacology. vol 49. issue 1. 2005-11-22. PMID:15992587. |
due to the homology between human chromosome 21 and mouse chromosome 16, trisomy 16 mice are considered animal models of down syndrome (ds). |
2005-11-22 |
2023-08-12 |
mouse |
| David K H Web. Optimizing therapy for myeloid disorders of Down syndrome. British journal of haematology. vol 131. issue 1. 2005-11-15. PMID:16173956. |
children with down syndrome (ds) are at increased risk of leukaemia. |
2005-11-15 |
2023-08-12 |
Not clear |
| M McCarron, M Gill, P McCallion, C Begle. Health co-morbidities in ageing persons with Down syndrome and Alzheimer's dementia. Journal of intellectual disability research : JIDR. vol 49. issue Pt 7. 2005-11-08. PMID:15966964. |
consideration of the relationship between physical and mental health co-morbidities in ageing persons with down syndrome (ds) and alzheimer's dementia (ad) is of clinical importance both from a care and resource perspective. |
2005-11-08 |
2023-08-12 |
Not clear |
| Irfan Ahmed, Tariq Ghafoor, Naseer Ahmed Samore, Mazhar Nazir Chatth. Down syndrome: clinical and cytogenetic analysis. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. vol 15. issue 7. 2005-11-08. PMID:16197873. |
to describe the clinical features and cytogenetic analysis of patients with down syndrome (ds). |
2005-11-08 |
2023-08-12 |
Not clear |
| Aideen O'Doherty, Sandra Ruf, Claire Mulligan, Victoria Hildreth, Mick L Errington, Sam Cooke, Abdul Sesay, Sonie Modino, Lesley Vanes, Diana Hernandez, Jacqueline M Linehan, Paul T Sharpe, Sebastian Brandner, Timothy V P Bliss, Deborah J Henderson, Dean Nizetic, Victor L J Tybulewicz, Elizabeth M C Fishe. An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science (New York, N.Y.). vol 309. issue 5743. 2005-10-20. PMID:16179473. |
this "transchromosomic" mouse line, tc1, is a model of trisomy 21, which manifests as down syndrome (ds) in humans, and has phenotypic alterations in behavior, synaptic plasticity, cerebellar neuronal number, heart development, and mandible size that relate to human ds. |
2005-10-20 |
2023-08-12 |
mouse |
| J Smigielska-Kuzia, W Sobaniec, W Kułak, L Boćkowski, E Sołowie. Quantitative EEG analysis of REM sleep in children with Down syndrome. Roczniki Akademii Medycznej w Bialymstoku (1995). vol 50 Suppl 1. 2005-10-11. PMID:16119618. |
the aim was to compare quantitative eeg analysis of rem sleep in children with down syndrome (ds) and normal age-matched controls. |
2005-10-11 |
2023-08-12 |
Not clear |
| Pierre L Roubertoux, Zoë Bichler, Walter Pinoteau, Zohra Seregaza, Sylvia Fortes, Marc Jamon, Desmond J Smith, Edward Rubin, Danièle Migliore-Samour, Michèle Carlie. Functional analysis of genes implicated in Down syndrome: 2. Laterality and corpus callosum size in mice transpolygenic for Down syndrome chromosomal region -1 (DCR-1). Behavior genetics. vol 35. issue 3. 2005-10-05. PMID:15864448. |
the association between atypical laterality and mental retardation has been reported several times, particularly in down syndrome (ds). |
2005-10-05 |
2023-08-12 |
mouse |
| S Saltvedt, H Almström, M Kublickas, L Valentin, R Bottinga, T-H Bui, M Cederholm, P Conner, B Dannberg, P Malcus, A Marsk, C Grunewal. Screening for Down syndrome based on maternal age or fetal nuchal translucency: a randomized controlled trial in 39,572 pregnancies. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. vol 25. issue 6. 2005-10-03. PMID:15912479. |
nuchal translucency (nt) screening increases antenatal detection of down syndrome (ds) compared to maternal age-based screening. |
2005-10-03 |
2023-08-12 |
Not clear |