| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arturo Figueroa, Scott R Collier, Tracy Baynard, Ifigenia Giannopoulou, Styliani Goulopoulou, Bo Fernhal. Impaired vagal modulation of heart rate in individuals with Down syndrome. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 15. issue 1. 2005-07-15. PMID:15768202. |
the attenuated heart rate (hr) and blood pressure (bp) response to exercise in individuals with down syndrome (ds) has been attributed to autonomic dysfunction, which has been associated with obesity. |
2005-07-15 |
2023-08-12 |
Not clear |
| Ofer Lehavi, Orna Aizenstein, Mark I Evans, Yuval Yaro. 2nd-trimester maternal serum human chorionic gonadotropin and alpha-fetoprotein levels in male and female fetuses with Down syndrome. Fetal diagnosis and therapy. vol 20. issue 3. 2005-07-12. PMID:15824504. |
this may potentially affect down syndrome (ds) screening such that a higher false-positive rate may occur in women carrying a female fetus, whereas a lower detection rate may result in those carrying males. |
2005-07-12 |
2023-08-12 |
human |
| In-Hyuk Chung, Sook-Hwan Lee, Kyo-Won Lee, Sang-hee Park, Kwang-Yul Cha, Nam-Soon Kim, Hyang-Sook Yoo, Yong Sung Kim, Suman Le. Gene expression analysis of cultured amniotic fluid cell with Down syndrome by DNA microarray. Journal of Korean medical science. vol 20. issue 1. 2005-07-11. PMID:15716609. |
complete or partial triplication of human chromosome 21 results in down syndrome (ds). |
2005-07-11 |
2023-08-12 |
human |
| Serafín Málaga, Rafael Pardo, Ignacio Málaga, Gonzalo Orejas, Joaquín Fernández-Tora. Renal involvement in Down syndrome. Pediatric nephrology (Berlin, Germany). vol 20. issue 5. 2005-07-06. PMID:15785939. |
kidney disease has not been considered a frequent complication in down syndrome (ds) patients; a variety of urological abnormalities and glomerulopathies have been reported in this population, and some ds patients develop chronic renal failure (crf). |
2005-07-06 |
2023-08-12 |
Not clear |
| Luciana Rodrigues Jacy da Silva, Naja Vergani, Luciano de Camargo Galdieri, Marianna Picarelli Ribeiro Porto, Silvia Bragagnolo Longhitano, Decio Brunoni, Vânia D'Almeida, Ana Beatriz Alvarez Pere. Relationship between polymorphisms in genes involved in homocysteine metabolism and maternal risk for Down syndrome in Brazil. American journal of medical genetics. Part A. vol 135. issue 3. 2005-07-05. PMID:15889417. |
in the present study, we determined polymorphisms of mthfr a222v (677c > t), mthfr e429a (1298a > c), mtrr i22m (66a > g), mtr d919g (2756a > g), and cbs 844ins68 and total plasma homocysteine levels (thcy) among 154 mothers of children with down syndrome (ds) and 158 control mothers from brazil. |
2005-07-05 |
2023-08-12 |
Not clear |
| Marilyne Bescond, Zohra Rahman. Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein. The international journal of biochemistry & cell biology. vol 37. issue 4. 2005-06-30. PMID:15694837. |
down syndrome (ds) is the most common genetic defect correlated with mental retardation and delayed development. |
2005-06-30 |
2023-08-12 |
human |
| Giuliana Miolo, Robin S Chapman, Heidi A Sindber. Sentence comprehension in adolescents with Down syndrome and typically developing children: role of sentence voice, visual context, and auditory-verbal short-term memory. Journal of speech, language, and hearing research : JSLHR. vol 48. issue 1. 2005-06-30. PMID:15938064. |
the authors evaluated the roles of auditory-verbal short-term memory, visual short-term memory, and group membership in predicting language comprehension, as measured by an experimental sentence comprehension task (sct) and the test for auditory comprehension of language--third edition (tacl-3; e. carrow-woolfolk, 1999) in 38 participants: 19 with down syndrome (ds), age 12 to 21 years, and 19 typically developing (td) children, age 3 to 5 years, matched on syntax comprehension, as measured by tacl-3 subtests ii and iii. |
2005-06-30 |
2023-08-12 |
human |
| Manuel Menénde. Down syndrome, Alzheimer's disease and seizures. Brain & development. vol 27. issue 4. 2005-06-28. PMID:15862185. |
neuropathologically, alzheimer-type abnormalities are demonstrated in patients with down syndrome (ds), both demented and nondemented and more than a half of patients with ds above 50 years develop alzheimer's disease (ad). |
2005-06-28 |
2023-08-12 |
Not clear |
| George T Capone, Marco A Grados, Walter E Kaufmann, Susana Bernad-Ripoll, Amy Jewel. Down syndrome and comorbid autism-spectrum disorder: characterization using the aberrant behavior checklist. American journal of medical genetics. Part A. vol 134. issue 4. 2005-06-27. PMID:15759262. |
to report on the cognitive and behavioral attributes of 61 children with down syndrome (ds) and autistic-spectrum disorder (asd) according to dsm-iv criteria; to determine the utility of the aberrant behavior checklist (abc) to characterize these subjects for research purposes; and to test the hypothesis that subjects with ds + asd could be distinguished from their typical ds peers using the abc. |
2005-06-27 |
2023-08-12 |
human |
| Ming-Hua Chen, Shyh-Jye Che. Cholelithiasis in Down syndrome. Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi. vol 45. issue 5. 2005-06-27. PMID:15868808. |
the aim of this study was to determine the association between down syndrome (ds) and cholelithiasis. |
2005-06-27 |
2023-08-12 |
human |
| John D Crispin. GATA1 in normal and malignant hematopoiesis. Seminars in cell & developmental biology. vol 16. issue 1. 2005-06-22. PMID:15659348. |
furthermore, few would have guessed that missense mutations in gata1 would cause inherited blood disorders, while acquired mutations would be found associated with essentially all cases of acute megakaryoblastic leukemia (amkl) in children with down syndrome (ds). |
2005-06-22 |
2023-08-12 |
Not clear |
| Linda Nelson, Julene K Johnson, Morris Freedman, Ira Lott, Jantje Groot, Marisa Chang, Norton William Milgram, Elizabeth Hea. Learning and memory as a function of age in Down syndrome: a study using animal-based tasks. Progress in neuro-psychopharmacology & biological psychiatry. vol 29. issue 3. 2005-06-17. PMID:15795053. |
individuals with down syndrome (ds) are at a high risk for developing alzheimer disease (ad) after the age 40; however, low levels of intellectual functioning, coupled with impaired language ability, confound the detection of ad. |
2005-06-17 |
2023-08-12 |
Not clear |
| K R Wøjdemann, A C Shalmi, M Christiansen, S O Larsen, K Sundberg, V Brocks, J Bang, B Nørgaard-Pedersen, A Tabo. Improved first-trimester Down syndrome screening performance by lowering the false-positive rate: a prospective study of 9941 low-risk women. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. vol 25. issue 3. 2005-06-16. PMID:15736185. |
to determine the performance of screening for down syndrome (ds) and other major chromosomal abnormalities using nuchal translucency (nt), free beta-human chorionic gonadotropin (beta-hcg) and pregnancy-associated plasma protein-a (papp-a) in a prospective study of a non-selected population. |
2005-06-16 |
2023-08-12 |
Not clear |
| P L Kaye, J Fiske, E J Bower, J T Newton, M Fenlo. Views and experiences of parents and siblings of adults with Down Syndrome regarding oral healthcare: a qualitative and quantitative study. British dental journal. vol 198. issue 9. 2005-06-14. PMID:15895058. |
to investigate experiences and expectations of parents/siblings of adults with down syndrome (ds) regarding oral healthcare, and explore factors impacting on access and experience of dental care for this group. |
2005-06-14 |
2023-08-12 |
Not clear |
| Stefano Vicari, Samantha Bellucci, Giovanni Augusto Carlesim. Visual and spatial long-term memory: differential pattern of impairments in Williams and Down syndromes. Developmental medicine and child neurology. vol 47. issue 5. 2005-06-07. PMID:15892372. |
this purpose of this study was to investigate visual-object and visual-spatial long-term memory (ltm) abilities in individuals with williams syndrome (ws) and down syndrome (ds). |
2005-06-07 |
2023-08-12 |
human |
| V Dimitrova, D Markov, T Chernev, Zh Karag'ozova, V Mazneĭkova, S Andonova, R Vŭzharov. [Ultrasound screening for Down syndrome and other chromosomal abnormalities by fetal nuchal translucency measurement between 11-14 weeks of gestation]. Akusherstvo i ginekologiia. vol 44. issue 1. 2005-06-06. PMID:15853009. |
to assess the feasibility of nuchal translucency [nt] measurement as a screening tool for down syndrome [ds] and other chromosomal anomalies [cha] between 11-14 weeks of gestation [w.g. |
2005-06-06 |
2023-08-12 |
Not clear |
| J Murphy, H M C V Hoey, M Philip, E F Roche, S Macken, P Mayne, D Duff, M O'Keefe, D McShane, E Fogarty, M O'Rega. Guidelines for the medical management of Irish children and adolescents with Down syndrome. Irish medical journal. vol 98. issue 2. 2005-05-26. PMID:15835512. |
down syndrome (ds) is the most common chromosomal cause of developmental disability in ireland. |
2005-05-26 |
2023-08-12 |
Not clear |
| John M Graham, Beth Rosner, Elisabeth Dykens, Jeannie Visootsa. Behavioral features of CHARGE syndrome (Hall-Hittner syndrome) comparison with Down syndrome, Prader-Willi syndrome, and Williams syndrome. American journal of medical genetics. Part A. vol 133A. issue 3. 2005-05-24. PMID:15637708. |
we conducted behavioral and personality assessments in 14 boys with hhs syndrome aged 6-21 years, and compared their characteristics with similar data from 20 age-matched boys with down syndrome (ds), 17 boys with prader-willi syndrome (pws), and 16 boys with williams syndrome (ws). |
2005-05-24 |
2023-08-12 |
Not clear |
| Alexander M Kleschevnikov, Pavel V Belichenko, Angela J Villar, Charles J Epstein, Robert C Malenka, William C Moble. Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 37. 2005-05-17. PMID:15371516. |
down syndrome (ds), a disorder caused by the presence of three copies of chromosome 21 (trisomy 21), is characterized by impairments in learning and memory attributable to dysfunction of the hippocampus. |
2005-05-17 |
2023-08-12 |
mouse |
| Rosa Ferrando Miguel, Arnold Pollak, Gert Lube. Metalloproteinase ADAMTS-1 but not ADAMTS-5 is manifold overexpressed in neurodegenerative disorders as Down syndrome, Alzheimer's and Pick's disease. Brain research. Molecular brain research. vol 133. issue 1. 2005-05-12. PMID:15661359. |
as the gene for this protein is encoded on chromosome 21 and maybe overexpressed due to the gene dosage hypothesis based upon the presence of a third chromosome in trisomy 21, we decided to study expression in down syndrome (ds) brain and used brains of patients with alzheimer's (ad) and pick's disease (pd) as controls. |
2005-05-12 |
2023-08-12 |
mouse |