Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Eliahu G Stoupel, Helena Frimer, Zvi Appelman, Ziva Ben-Neriah, Hanna Dar, Moshe D Fejgin, Ruth Gershoni-Baruch, Esther Manor, Gad Barkai, Stavit Shalev, Zully Gelman-Kohan, Orit Reish, Dorit Lev, Bella Davidov, Boleslaw Goldman, Mordechai Shoha. Chromosome aberration and environmental physical activity: Down syndrome and solar and cosmic ray activity, Israel, 1990-2000. International journal of biometeorology. vol 50. issue 1. 2006-06-23. PMID:15988607. |
the aim of this study was to investigate a possible link between the number of down syndrome (ds) cases detected prenatally or at birth yearly in israel over a 10-year period compared with the levels of solar and cosmic ray activity 1 year before the detection or birth of each affected child. |
2006-06-23 |
2023-08-12 |
Not clear |
Thomas Cushing, Carol L Clericuzio, Carla S Wilson, Jeffrey W Taub, Yubin Ge, Kaaren K Reichard, Stuart S Winte. Risk for leukemia in infants without Down syndrome who have transient myeloproliferative disorder. The Journal of pediatrics. vol 148. issue 5. 2006-06-22. PMID:16737888. |
transient myeloproliferative disorder (tmd) occurs in 10% of infants with down syndrome (ds). |
2006-06-22 |
2023-08-12 |
Not clear |
Melicia C Whitt-Glover, Kristen L O'Neill, Nicolas Stettle. Physical activity patterns in children with and without Down syndrome. Pediatric rehabilitation. vol 9. issue 2. 2006-06-14. PMID:16449075. |
to describe physical activity (pa) patterns in children with down syndrome (ds) compared to their unaffected siblings. |
2006-06-14 |
2023-08-12 |
Not clear |
María-Luisa Martínez-Frías, Belén Pérez, Lourdes R Desviat, Margarita Castro, Fátima Leal, Laura Rodríguez, Elena Mansilla, María-Luisa Martínez-Fernández, Eva Bermejo, Elvira Rodríguez-Pinilla, David Prieto, Magdalena Ugart. Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome? American journal of medical genetics. Part A. vol 140. issue 9. 2006-06-13. PMID:16575899. |
this study was aimed at analyzing the effect of mutations in three non-synonymous snp genes (677c > t and 1298a > c of the methylenetetrahydrofolate reductase (mthfr) gene, and 66a > g in the mtrr gene) on total plasmatic homocysteine (hcy), in 91 mothers of down syndrome (ds) infants and 90 control mothers. |
2006-06-13 |
2023-08-12 |
Not clear |
Xianfang Meng, Jing Shi, Bin Peng, Xiaojing Zou, Chun Zhan. Effect of mouse Sim2 gene on the cell cycle of PC12 cells. Cell biology international. vol 30. issue 4. 2006-06-07. PMID:16530433. |
sim2 gene plays an important role in the pathogenesis of down syndrome (ds). |
2006-06-07 |
2023-08-12 |
mouse |
Ibrahim Caner, Hasim Olgun, Mustafa Buyukavci, Ayhan Tastekin, Rahmi Or. A giant thrombus in the right ventricle of a newborn with Down syndrome: successful treatment with rt-PA. Journal of pediatric hematology/oncology. vol 28. issue 3. 2006-06-02. PMID:16679932. |
a giant thrombus in the right ventricle of a newborn with down syndrome: successful treatment with rt-pa. an association between thromboembolic events and down syndrome (ds) has been increasingly reported in the literature. |
2006-06-02 |
2023-08-12 |
Not clear |
Yoko Kondo, Seiji Mizuno, Kei Ohara, Takeshi Nakamura, Kenichiro Yamada, Shunji Yamamori, Chiemi Hayakawa, Takashi Ishii, Yasukazu Yamada, Nobuaki Wakamats. Two cases of partial trisomy 21 (pter-q22.1) without the major features of Down syndrome. American journal of medical genetics. Part A. vol 140. issue 3. 2006-05-30. PMID:16411203. |
we report two cases of partial trisomy 21 with clinical features distinct from down syndrome (ds). |
2006-05-30 |
2023-08-12 |
Not clear |
L Massaccesi, M M Corsi, C J Baquero-Herrera, F Licastro, C Tringali, B Venerando, A Lombardo, A Alberghino, Giancarlo Go. Erythrocyte glycohydrolases in subjects with trisomy 21: could Down's syndrome be a model of accelerated ageing? Mechanisms of ageing and development. vol 127. issue 4. 2006-05-25. PMID:16460783. |
we studied some erythrocyte glycohydrolases, erythrocyte membrane fluidity, plasma hydroperoxides and total antioxidant defences in 23 down syndrome (ds) individuals in comparison with healthy age-matched and elderly controls. |
2006-05-25 |
2023-08-12 |
human |
Isis Quezado Magalhães, Alessandra Splendore, Mariana Emerenciano, Alexandre Figueiredo, Iris Ferrari, Maria S Pombo-de-Oliveir. GATA1 mutations in acute leukemia in children with Down syndrome. Cancer genetics and cytogenetics. vol 166. issue 2. 2006-05-25. PMID:16631466. |
it has been reported that somatic mutations in the x-linked gata1 gene are present in hematological clonal disorders in children with down syndrome (ds). |
2006-05-25 |
2023-08-12 |
Not clear |
P Kittler, S J Krinsky-McHale, D A Devenn. Verbal intrusions precede memory decline in adults with Down syndrome. Journal of intellectual disability research : JIDR. vol 50. issue Pt 1. 2006-05-09. PMID:16316425. |
the purpose of this study was to longitudinally examine the production of verbal intrusions among middle-aged adults with down syndrome (ds) and unspecified intellectual disability (id) to determine whether producing verbal intrusions at one point in time was related to subsequent verbal memory performance. |
2006-05-09 |
2023-08-12 |
Not clear |
Digby Elliott, Timothy N Welsh, James Lyons, Steve Hansen, Melinda W. The visual regulation of goal-directed reaching movements in adults with Williams syndrome, Down syndrome, and other developmental delays. Motor control. vol 10. issue 1. 2006-05-02. PMID:16571907. |
compared to persons with down syndrome (ds) at the same developmental level, individuals with ws generally exhibit superior expressive language abilities, but have difficulty with tasks that require the visual control of movement. |
2006-05-02 |
2023-08-12 |
human |
Aaron B Caughey, Deirdre J Lyell, A Eugene Washington, Roy A Filly, Mary E Norto. Ultrasound screening of fetuses at increased risk for Down syndrome: how many missed diagnoses? Prenatal diagnosis. vol 26. issue 1. 2006-04-25. PMID:16378329. |
to determine the number of down syndrome (ds) fetuses identified, amniocenteses performed, and procedure-related losses incurred when second-trimester ultrasound is used to screen high-risk patients in order to determine who should undergo an amniocentesis. |
2006-04-25 |
2023-08-12 |
Not clear |
Fuad I Abba. Congenital heart diseases and other major anomalies in patients with Down syndrome. Saudi medical journal. vol 27. issue 2. 2006-04-24. PMID:16501680. |
to determine the frequency and types of congenital heart diseases (chds) and other congenital anomalies among down syndrome (ds) patients, and the short-term survival rate. |
2006-04-24 |
2023-08-12 |
Not clear |
Chi-Ming Li, Meirong Guo, Martha Salas, Nicole Schupf, Wayne Silverman, Warren B Zigman, Sameera Husain, Dorothy Warburton, Harshwardhan Thaker, Benjamin Tyck. Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21. BMC medical genetics. vol 7. 2006-04-24. PMID:16539728. |
down syndrome (ds) is caused by trisomy 21 (+21), but the aberrations in gene expression resulting from this chromosomal aneuploidy are not yet completely understood. |
2006-04-24 |
2023-08-12 |
Not clear |
Randall J Roper, Heidi K St John, Jessica Philip, Ann Lawler, Roger H Reeve. Perinatal loss of Ts65Dn Down syndrome mice. Genetics. vol 172. issue 1. 2006-04-17. PMID:16172497. |
these mice display a number of phenotypes that are directly comparable to those in humans with trisomy 21 and are the most widely used animal model of down syndrome (ds). |
2006-04-17 |
2023-08-12 |
mouse |
Anupama Rao, Robert K Hills, Charles Stiller, Brenda E Gibson, Siebold S N de Graaf, Ian M Hann, Aengus O'Marcaigh, Keith Wheatley, David K H Web. Treatment for myeloid leukaemia of Down syndrome: population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials. British journal of haematology. vol 132. issue 5. 2006-04-11. PMID:16445830. |
down syndrome (ds) children are at an increased risk of developing myelodysplasia and acute myeloid leukaemia (aml). |
2006-04-11 |
2023-08-12 |
Not clear |
Jean-Pierre Bourquin, Aravind Subramanian, Claudia Langebrake, Dirk Reinhardt, Olivier Bernard, Paola Ballerini, André Baruchel, Hélène Cavé, Nicole Dastugue, Henrik Hasle, Gertjan L Kaspers, Michel Lessard, Lucienne Michaux, Paresh Vyas, Elisabeth van Wering, Christian M Zwaan, Todd R Golub, Stuart H Orki. Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 9. 2006-04-10. PMID:16492768. |
individuals with down syndrome (ds) are predisposed to develop acute megakaryoblastic leukemia (amkl), characterized by expression of truncated gata1 transcription factor protein (gata1s) due to somatic mutation. |
2006-04-10 |
2023-08-12 |
Not clear |
Yubin Ge, Alan A Dombkowski, Katherine M LaFiura, Dana Tatman, Ravikiran S Yedidi, Mark L Stout, Steven A Buck, Gita Massey, David L Becton, Howard J Weinstein, Yaddanapudi Ravindranath, Larry H Matherly, Jeffrey W Tau. Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia. Blood. vol 107. issue 4. 2006-04-04. PMID:16249385. |
children with down syndrome (ds) with acute megakaryocytic leukemia (amkl) have very high survival rates compared with non-ds amkl patients. |
2006-04-04 |
2023-08-12 |
Not clear |
Chie Harashima, David M Jacobowitz, Jassir Witta, Rosemary C Borke, Tyler K Best, Richard J Siarey, Zygmunt Galdzick. Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome. The Journal of comparative neurology. vol 494. issue 5. 2006-04-04. PMID:16374808. |
ts65dn, a mouse model of down syndrome (ds), demonstrates abnormal hippocampal synaptic plasticity and behavioral abnormalities related to spatial learning and memory. |
2006-04-04 |
2023-08-12 |
mouse |
Thibaut Culty, Nicolas Barry Delongchamps, Nicolas Barry-Delonchamps, Sebastien Dominique, Frederique Servin, Vincent Ravery, Laurent Boccon-Gibo. Posterior urethral valves in adult with Down syndrome. Urology. vol 67. issue 2. 2006-03-31. PMID:16461111. |
posterior urethral valves (puvs) in patients with down syndrome (ds) have been previously described. |
2006-03-31 |
2023-08-12 |
Not clear |