| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kristiina Patja, Eero Pukkala, Reijo Sund, Matti Iivanainen, Markus Kask. Cancer incidence of persons with Down syndrome in Finland: a population-based study. International journal of cancer. vol 118. issue 7. 2006-03-28. PMID:16231334. |
individuals with down syndrome (ds) have a predisposition to leukaemia and testicular cancer, but data on the incidence of cancers are yet sparse. |
2006-03-28 |
2023-08-12 |
Not clear |
| M Ayberk Kurt, M Ilker Kafa, Mara Dierssen, D Ceri Davie. Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome. Brain research. vol 1022. issue 1-2. 2006-03-23. PMID:15353219. |
ts65dn mice are partially trisomic for the distal region of mmu16, which is homologous with the obligate segment of hsa21 triplicated in down syndrome (ds). |
2006-03-23 |
2023-08-12 |
mouse |
| Karen Fung, Paul J Alliso. A comparison of caries rates in non-institutionalized individuals with and without Down syndrome. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 25. issue 6. 2006-03-23. PMID:16463603. |
the caries rate of people with down syndrome (ds) was compared to an age-matched control population without ds. |
2006-03-23 |
2023-08-12 |
human |
| Zuhal Hamurcu, Halil Demirtas, Sefer Kumanda. Flow cytometric comparison of RNA content in peripheral blood mononuclear cells of Down syndrome patients and control individuals. Cytometry. Part B, Clinical cytometry. vol 70. issue 1. 2006-03-15. PMID:16353214. |
trisomy 21 or down syndrome (ds) is the most common genetic cause of mental retardation associated with the immunologic and other known defects. |
2006-03-15 |
2023-08-12 |
Not clear |
| Hidemitsu Kurosawa, Tatsuo Tsuboi, Hagane Shimaoka, Mayuko Okuya, Daisuke Nakajima, Takayuki Matsunaga, Susumu Hagisawa, Yuya Sato, Kenichi Sugita, Mitsuoki Eguch. [Long-term remission in an acute monoblastic leukemia patient with down syndrome after cord blood transplantation]. [Rinsho ketsueki] The Japanese journal of clinical hematology. vol 46. issue 4. 2006-03-14. PMID:16444960. |
a 4-year-old boy with down syndrome (ds) was diagnosed as having acute monoblastic leukemia (aml-m5a). |
2006-03-14 |
2023-08-12 |
Not clear |
| Joo-Ho Shin, Talin Gulesserian, Emmanuelle Verger, Jean-Maurice Delabar, Gert Lube. Protein dysregulation in mouse hippocampus polytransgenic for chromosome 21 structures in the Down Syndrome Critical Region. Journal of proteome research. vol 5. issue 1. 2006-03-10. PMID:16396494. |
mice polytransgenic for chromosome 21 genes dscr3, 5, 6, 9, and ttc3 within the down syndrome critical region-1 represent an animal model for down syndrome (ds). |
2006-03-10 |
2023-08-12 |
mouse |
| F W van Leeuwen, P van Tijn, M A F Sonnemans, B Hobo, D M A Mann, C Van Broeckhoven, S Kumar-Singh, P Cras, G Leuba, A Savioz, M L C Maat-Schieman, H Yamaguchi, J M Kros, W Kamphorst, E M Hol, R A I de Vos, D F Fische. Frameshift proteins in autosomal dominant forms of Alzheimer disease and other tauopathies. Neurology. vol 66. issue 2 Suppl 1. 2006-03-09. PMID:16432153. |
frameshift (+1) proteins such as app(+1) and ubb(+1) accumulate in sporadic cases of alzheimer disease (ad) and in older subjects with down syndrome (ds). |
2006-03-09 |
2023-08-12 |
human |
| Samuel Deutsch, Robert Lyle, Emmanouil T Dermitzakis, Homa Attar, Lakshman Subrahmanyan, Corinne Gehrig, Leila Parand, Maryline Gagnebin, Jacques Rougemont, C Victor Jongeneel, Stylianos E Antonaraki. Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes. Human molecular genetics. vol 14. issue 23. 2006-03-07. PMID:16251198. |
we investigated the patterns of gene expression variation in a 25 mb region of human chromosome 21, which has been associated with many down syndrome (ds) phenotypes. |
2006-03-07 |
2023-08-12 |
human |
| David F Fischer, Renske van Dijk, Jacqueline A Sluijs, Suresh M Nair, Marco Racchi, Christiaan N Levelt, Fred W van Leeuwen, Elly M Ho. Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 19. issue 11. 2006-03-06. PMID:16126912. |
down syndrome (ds) patients suffer from mental retardation, but also display enhanced beta-app production and develop cortical amyloid plaques at an early age. |
2006-03-06 |
2023-08-12 |
human |
| Nalan Imamoglu, Halil Demirtas, Ali Ilte. NOR expression increases in interphase lymphocytes of Down syndrome babies/children as AgNORs surface, according to the mitogen concentration in the culture medium. Micron (Oxford, England : 1993). vol 37. issue 2. 2006-03-06. PMID:16233978. |
the extra chromosome 21 of down syndrome (ds) or trisomy 21 patients contains an average of 40 extra copies of rrna genes and the in vivo/in vitro regulation of the activity of these genes is not fully understood. |
2006-03-06 |
2023-08-12 |
Not clear |
| Suttur S Malini, Nallur B Ramachandr. Influence of advanced age of maternal grandmothers on Down syndrome. BMC medical genetics. vol 7. 2006-03-06. PMID:16412239. |
down syndrome (ds) is the most common chromosomal anomaly associated with mental retardation. |
2006-03-06 |
2023-08-12 |
Not clear |
| Kevin S Heffernan, Tracy Baynard, Styliani Goulopoulou, Ifigenia Giannopoulou, Scott R Collier, Arturo Figueroa, Bo Fernhal. Baroreflex sensitivity during static exercise in individuals with Down Syndrome. Medicine and science in sports and exercise. vol 37. issue 12. 2006-02-24. PMID:16331125. |
individuals with down syndrome (ds) have altered heart rate (hr) and blood pressure (bp) responses to orthostatic challenges and isometric handgrip (ihg) exercise, suggesting possible alteration in baroreflex sensitivity. |
2006-02-24 |
2023-08-12 |
Not clear |
| Stefano Vicari, Samantha Bellucci, Giovanni Augusto Carlesim. Evidence from two genetic syndromes for the independence of spatial and visual working memory. Developmental medicine and child neurology. vol 48. issue 2. 2006-02-24. PMID:16417668. |
this study aimed at investigating the possible dissociation between visual-object and visual-spatial working memory (wm) in individuals with williams syndrome (ws) and down syndrome (ds). |
2006-02-24 |
2023-08-12 |
human |
| Yung-Jung Chen, Peng-Cheng Fan. Sensory evoked potentials in infants with Down syndrome. Acta paediatrica (Oslo, Norway : 1992). vol 94. issue 11. 2006-02-23. PMID:16303699. |
to investigate the sensory functions of the peripheral to central pathways in infants with down syndrome (ds) by sensory evoked potentials. |
2006-02-23 |
2023-08-12 |
Not clear |
| Cynthia L Lewis, Maria A Fragala-Pinkha. Effects of aerobic conditioning and strength training on a child with Down syndrome: a case study. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 17. issue 1. 2006-01-26. PMID:16357655. |
to determine the effects of a home exercise program of combined aerobic and strength training on fitness with a 10.5-year-old girl with down syndrome (ds). |
2006-01-26 |
2023-08-12 |
Not clear |
| S L Sherman, S B Freeman, E G Allen, N E Lam. Risk factors for nondisjunction of trisomy 21. Cytogenetic and genome research. vol 111. issue 3-4. 2006-01-23. PMID:16192705. |
the leading cause of down syndrome (ds) is nondisjunction of chromosome 21 occurring during the formation of gametes. |
2006-01-23 |
2023-08-12 |
Not clear |
| Isidro Ferrer, Marta Barrachina, Berta Puig, M Martínez de Lagrán, Eulalia Martí, Jesús Avila, Mara Diersse. Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:16242644. |
dyrk1a, dual-specificity tyrosine-regulated kinase 1a, maps to human chromosome 21 within the down syndrome (ds) critical region. |
2006-01-23 |
2023-08-12 |
mouse |
| Elizabeth Kay-Raining Bird, Patricia Cleave, Natacha Trudeau, Elin Thordardottir, Ann Sutton, Amy Thorp. The language abilities of bilingual children with Down syndrome. American journal of speech-language pathology. vol 14. issue 3. 2006-01-18. PMID:16229670. |
children with down syndrome (ds) have cognitive disabilities resulting from trisomy 21. |
2006-01-18 |
2023-08-12 |
Not clear |
| Paul J Allison, Herenia P Lawrenc. Validity of an instrument assessing oral health problems in people with Down syndrome. Community dental health. vol 22. issue 4. 2006-01-12. PMID:16379160. |
the aim of this study was to validate a proxy measure of oral health designed to be completed by the english-speaking parents of people with down syndrome (ds) aged four years or more. |
2006-01-12 |
2023-08-12 |
Not clear |
| Yvette C M de Hingh, Petrus W van der Vossen, Eugenie F A Gemen, André B Mulder, Wim C J Hop, Frank Brus, Esther de Vrie. Intrinsic abnormalities of lymphocyte counts in children with down syndrome. The Journal of pediatrics. vol 147. issue 6. 2006-01-11. PMID:16356423. |
down syndrome (ds) is associated with an increased frequency of infections, hematologic malignancies, and autoimmune diseases, suggesting that immunodeficiency is an integral part of ds that contributes significantly to the observed increased morbidity and mortality. |
2006-01-11 |
2023-08-12 |
Not clear |