| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joo-Ho Shin, Talin Gulesserian, Emmanuelle Verger, Jean-Maurice Delabar, Gert Lube. Protein dysregulation in mouse hippocampus polytransgenic for chromosome 21 structures in the Down Syndrome Critical Region. Journal of proteome research. vol 5. issue 1. 2006-03-10. PMID:16396494. |
mice polytransgenic for chromosome 21 genes dscr3, 5, 6, 9, and ttc3 within the down syndrome critical region-1 represent an animal model for down syndrome (ds). |
2006-03-10 |
2023-08-12 |
mouse |
| F W van Leeuwen, P van Tijn, M A F Sonnemans, B Hobo, D M A Mann, C Van Broeckhoven, S Kumar-Singh, P Cras, G Leuba, A Savioz, M L C Maat-Schieman, H Yamaguchi, J M Kros, W Kamphorst, E M Hol, R A I de Vos, D F Fische. Frameshift proteins in autosomal dominant forms of Alzheimer disease and other tauopathies. Neurology. vol 66. issue 2 Suppl 1. 2006-03-09. PMID:16432153. |
frameshift (+1) proteins such as app(+1) and ubb(+1) accumulate in sporadic cases of alzheimer disease (ad) and in older subjects with down syndrome (ds). |
2006-03-09 |
2023-08-12 |
human |
| Samuel Deutsch, Robert Lyle, Emmanouil T Dermitzakis, Homa Attar, Lakshman Subrahmanyan, Corinne Gehrig, Leila Parand, Maryline Gagnebin, Jacques Rougemont, C Victor Jongeneel, Stylianos E Antonaraki. Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes. Human molecular genetics. vol 14. issue 23. 2006-03-07. PMID:16251198. |
we investigated the patterns of gene expression variation in a 25 mb region of human chromosome 21, which has been associated with many down syndrome (ds) phenotypes. |
2006-03-07 |
2023-08-12 |
human |
| David F Fischer, Renske van Dijk, Jacqueline A Sluijs, Suresh M Nair, Marco Racchi, Christiaan N Levelt, Fred W van Leeuwen, Elly M Ho. Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 19. issue 11. 2006-03-06. PMID:16126912. |
down syndrome (ds) patients suffer from mental retardation, but also display enhanced beta-app production and develop cortical amyloid plaques at an early age. |
2006-03-06 |
2023-08-12 |
human |
| Nalan Imamoglu, Halil Demirtas, Ali Ilte. NOR expression increases in interphase lymphocytes of Down syndrome babies/children as AgNORs surface, according to the mitogen concentration in the culture medium. Micron (Oxford, England : 1993). vol 37. issue 2. 2006-03-06. PMID:16233978. |
the extra chromosome 21 of down syndrome (ds) or trisomy 21 patients contains an average of 40 extra copies of rrna genes and the in vivo/in vitro regulation of the activity of these genes is not fully understood. |
2006-03-06 |
2023-08-12 |
Not clear |
| Suttur S Malini, Nallur B Ramachandr. Influence of advanced age of maternal grandmothers on Down syndrome. BMC medical genetics. vol 7. 2006-03-06. PMID:16412239. |
down syndrome (ds) is the most common chromosomal anomaly associated with mental retardation. |
2006-03-06 |
2023-08-12 |
Not clear |
| Kevin S Heffernan, Tracy Baynard, Styliani Goulopoulou, Ifigenia Giannopoulou, Scott R Collier, Arturo Figueroa, Bo Fernhal. Baroreflex sensitivity during static exercise in individuals with Down Syndrome. Medicine and science in sports and exercise. vol 37. issue 12. 2006-02-24. PMID:16331125. |
individuals with down syndrome (ds) have altered heart rate (hr) and blood pressure (bp) responses to orthostatic challenges and isometric handgrip (ihg) exercise, suggesting possible alteration in baroreflex sensitivity. |
2006-02-24 |
2023-08-12 |
Not clear |
| Stefano Vicari, Samantha Bellucci, Giovanni Augusto Carlesim. Evidence from two genetic syndromes for the independence of spatial and visual working memory. Developmental medicine and child neurology. vol 48. issue 2. 2006-02-24. PMID:16417668. |
this study aimed at investigating the possible dissociation between visual-object and visual-spatial working memory (wm) in individuals with williams syndrome (ws) and down syndrome (ds). |
2006-02-24 |
2023-08-12 |
human |
| Yung-Jung Chen, Peng-Cheng Fan. Sensory evoked potentials in infants with Down syndrome. Acta paediatrica (Oslo, Norway : 1992). vol 94. issue 11. 2006-02-23. PMID:16303699. |
to investigate the sensory functions of the peripheral to central pathways in infants with down syndrome (ds) by sensory evoked potentials. |
2006-02-23 |
2023-08-12 |
Not clear |
| Cynthia L Lewis, Maria A Fragala-Pinkha. Effects of aerobic conditioning and strength training on a child with Down syndrome: a case study. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 17. issue 1. 2006-01-26. PMID:16357655. |
to determine the effects of a home exercise program of combined aerobic and strength training on fitness with a 10.5-year-old girl with down syndrome (ds). |
2006-01-26 |
2023-08-12 |
Not clear |
| S L Sherman, S B Freeman, E G Allen, N E Lam. Risk factors for nondisjunction of trisomy 21. Cytogenetic and genome research. vol 111. issue 3-4. 2006-01-23. PMID:16192705. |
the leading cause of down syndrome (ds) is nondisjunction of chromosome 21 occurring during the formation of gametes. |
2006-01-23 |
2023-08-12 |
Not clear |
| Isidro Ferrer, Marta Barrachina, Berta Puig, M Martínez de Lagrán, Eulalia Martí, Jesús Avila, Mara Diersse. Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:16242644. |
dyrk1a, dual-specificity tyrosine-regulated kinase 1a, maps to human chromosome 21 within the down syndrome (ds) critical region. |
2006-01-23 |
2023-08-12 |
mouse |
| Elizabeth Kay-Raining Bird, Patricia Cleave, Natacha Trudeau, Elin Thordardottir, Ann Sutton, Amy Thorp. The language abilities of bilingual children with Down syndrome. American journal of speech-language pathology. vol 14. issue 3. 2006-01-18. PMID:16229670. |
children with down syndrome (ds) have cognitive disabilities resulting from trisomy 21. |
2006-01-18 |
2023-08-12 |
Not clear |
| Paul J Allison, Herenia P Lawrenc. Validity of an instrument assessing oral health problems in people with Down syndrome. Community dental health. vol 22. issue 4. 2006-01-12. PMID:16379160. |
the aim of this study was to validate a proxy measure of oral health designed to be completed by the english-speaking parents of people with down syndrome (ds) aged four years or more. |
2006-01-12 |
2023-08-12 |
Not clear |
| Yvette C M de Hingh, Petrus W van der Vossen, Eugenie F A Gemen, André B Mulder, Wim C J Hop, Frank Brus, Esther de Vrie. Intrinsic abnormalities of lymphocyte counts in children with down syndrome. The Journal of pediatrics. vol 147. issue 6. 2006-01-11. PMID:16356423. |
down syndrome (ds) is associated with an increased frequency of infections, hematologic malignancies, and autoimmune diseases, suggesting that immunodeficiency is an integral part of ds that contributes significantly to the observed increased morbidity and mortality. |
2006-01-11 |
2023-08-12 |
Not clear |
| Ferdinando Iellamo, Alberto Galante, Jacopo M Legramante, Maria Enrichetta Lippi, Claudia Condoluci, Giorgio Albertini, Maurizio Volterran. Altered autonomic cardiac regulation in individuals with Down syndrome. American journal of physiology. Heart and circulatory physiology. vol 289. issue 6. 2006-01-10. PMID:16024564. |
ten subjects with down syndrome (ds) and ten gender-and age-matched healthy control subjects were studied at rest and during active orthostatism, which induces reciprocal changes in sympathetic and parasympathetic traffic to the heart. |
2006-01-10 |
2023-08-12 |
human |
| Ron Maymon, Orna Levinsohn-Tavor, Howard Cuckle, Yosef Tovbin, Eli Dreazen, Yifat Wiener, Arie Herma. Second trimester ultrasound prenasal thickness combined with nasal bone length: a new method of Down syndrome screening. Prenatal diagnosis. vol 25. issue 10. 2006-01-06. PMID:16088862. |
to evaluate ultrasound prenasal thickness (pt) as a way of enhancing the down syndrome (ds) screening performance of second-trimester nasal bone (nb) length measurement. |
2006-01-06 |
2023-08-12 |
Not clear |
| James A Whitlock, Harland N Sather, Paul Gaynon, Leslie L Robison, Robert J Wells, Michael Trigg, Nyla A Heerema, Smita Bhati. Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study. Blood. vol 106. issue 13. 2006-01-06. PMID:16109782. |
we assessed the outcome of children with down syndrome (ds) and acute lymphoblastic leukemia (all) receiving contemporary risk-based therapy by evaluating clinical and biologic features and outcome of children with all, with or without ds, enrolled in children's cancer group (ccg) protocols between 1983 and 1995. |
2006-01-06 |
2023-08-12 |
Not clear |
| Anshu Awasthi, Reena Das, Neelam Varma, Jasmina Ahluwalia, Anju Gupta, R K Marwaha, Gurjeewan Garewa. Hematological disorders in Down syndrome: ten-year experience at a Tertiary Care Centre in North India. Pediatric hematology and oncology. vol 22. issue 6. 2006-01-03. PMID:16169817. |
a total of 239 cases of down syndrome (ds) were seen in the genetic clinic between 1992 and 2003, of which of 15 had hematological manifestations at presentation. |
2006-01-03 |
2023-08-12 |
Not clear |
| Ron Maymon, Ortal Neeman, Adrian Shulman, Hadar Rosen, Arie Herma. Current concepts of Down syndrome screening tests in assisted reproduction twin pregnancies: another double trouble. Prenatal diagnosis. vol 25. issue 9. 2005-12-29. PMID:16170837. |
various methods of screening for down syndrome (ds) were introduced in clinical practice during the last two decades, and specific problems were encountered when they were applied for twin pregnancies. |
2005-12-29 |
2023-08-12 |
human |