| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Nardone, R Marth, H Ausserer, A Bratti, F Tezzo. Reduced short latency afferent inhibition in patients with Down syndrome and Alzheimer-type dementia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 117. issue 10. 2006-12-15. PMID:16931146. |
adults with down syndrome (ds) develop progressive cognitive impairment resembling the cognitive profile of alzheimer's disease (ad). |
2006-12-15 |
2023-08-12 |
human |
| Eun Joo Kim, Jee Young Sung, Hyun Jung Lee, Hyewhon Rhim, Masato Hasegawa, Takeshi Iwatsubo, Do Sik Min, Jongsun Kim, Seung R Paik, Kwang Chul Chun. Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation. The Journal of biological chemistry. vol 281. issue 44. 2006-12-11. PMID:16959772. |
alpha-synuclein, the major component of lbs, is observed in the brain of down syndrome (ds) patients with ad. |
2006-12-11 |
2023-08-12 |
human |
| David W Evans, Kristin Canavera, F Lee Kleinpeter, Elise Maccubbin, Ken Tag. The fears, phobias and anxieties of children with autism spectrum disorders and Down syndrome: comparisons with developmentally and chronologically age matched children. Child psychiatry and human development. vol 36. issue 1. 2006-12-07. PMID:16049642. |
this study compared the fears and behavior problems of 25 children with an autism spectrum disorder (asd), 43 children with down syndrome (ds), 45 mental age (ma) matched children, and 37 chronologically age (ca) matched children. |
2006-12-07 |
2023-08-12 |
human |
| Clara S Moor. Postnatal lethality and cardiac anomalies in the Ts65Dn Down syndrome mouse model. Mammalian genome : official journal of the International Mammalian Genome Society. vol 17. issue 10. 2006-12-07. PMID:17019652. |
the ts65dn mouse is a well-studied model for down syndrome (ds). |
2006-12-07 |
2023-08-12 |
mouse |
| Willemijn M Meijer, Martha M Werler, Carol Louik, Sonia Hernandez-Diaz, Lolkje T W de Jong-van den Berg, Allen A Mitchel. Can folic acid protect against congenital heart defects in Down syndrome? Birth defects research. Part A, Clinical and molecular teratology. vol 76. issue 10. 2006-12-07. PMID:17051586. |
down syndrome (ds) infants are known to have a high frequency of heart anomalies. |
2006-12-07 |
2023-08-12 |
Not clear |
| George M Savva, Joan K Morris, David E Mutton, Eva Alberma. Maternal age-specific fetal loss rates in Down syndrome pregnancies. Prenatal diagnosis. vol 26. issue 6. 2006-12-01. PMID:16634111. |
pregnancies affected by down syndrome (ds) have a greater risk of spontaneous fetal loss than those that are unaffected. |
2006-12-01 |
2023-08-12 |
Not clear |
| Yoshiki Nishizawa, Takehisa Fujita, Kazuhiko Matsuoka, Hirofumi Nakagaw. Contact pressure distribution features in Down syndrome infants in supine and prone positions, analyzed by photoelastic methods. Pediatrics international : official journal of the Japan Pediatric Society. vol 48. issue 5. 2006-12-01. PMID:16970787. |
local force distribution supporting the bodyweight of infants with down syndrome (ds) appears to be different from that of healthy controls. |
2006-12-01 |
2023-08-12 |
Not clear |
| Mustafa Sahin, Neslihan Bascil Tutuncu, Mehmet Kanbay, Nilgun Demirag Guvene. Surgery for hyperthyroidism in Down syndrome: case report. The Mount Sinai journal of medicine, New York. vol 73. issue 5. 2006-11-28. PMID:17008939. |
thyroid disorders are common in patients with down syndrome (ds). |
2006-11-28 |
2023-08-12 |
Not clear |
| Osman N Sanye. Down syndrome and sport participation. Current sports medicine reports. vol 5. issue 6. 2006-11-27. PMID:17067499. |
individuals with down syndrome (ds) derive measurable physiologic and psychologic benefits from participation in physical activities and sports. |
2006-11-27 |
2023-08-12 |
Not clear |
| David S Brin. Transient leukemia (transient myeloproliferative disorder, transient abnormal myelopoiesis) of Down syndrome. Advances in anatomic pathology. vol 13. issue 5. 2006-11-14. PMID:16998319. |
transient leukemia of down syndrome (ds-tl), also known as transient myeloproliferative disorder of down syndrome (ds) and transient abnormal myelopoiesis of ds, occurs in approximately 10% of ds neonates and in phenotypically normal neonates with trisomy 21 mosaicism. |
2006-11-14 |
2023-08-12 |
Not clear |
| L Verucci, D Menghini, S Vicar. Reading skills and phonological awareness acquisition in Down syndrome. Journal of intellectual disability research : JIDR. vol 50. issue Pt 7. 2006-11-09. PMID:16774633. |
although reading abilities play a fundamental role in the acquisition of personal autonomy, up until now studies investigating these abilities in down syndrome (ds) are aimed at defining educational or rehabilitation acquisition. |
2006-11-09 |
2023-08-12 |
human |
| Ali Al-Ahmari, Niketa Shah, Lillian Sung, Alvin Zipursky, Johann Hitzle. Long-term results of an ultra low-dose cytarabine-based regimen for the treatment of acute megakaryoblastic leukaemia in children with Down syndrome. British journal of haematology. vol 133. issue 6. 2006-11-08. PMID:16704441. |
children with acute megakaryoblastic leukaemia (amkl) and down syndrome (ds) show a favourable response to chemotherapy, probably due to increased sensitivity of the leukaemic blasts to cytarabine. |
2006-11-08 |
2023-08-12 |
Not clear |
| Brian G Skotko, Susan P Levin. What the other children are thinking: brothers and sisters of persons with Down syndrome. American journal of medical genetics. Part C, Seminars in medical genetics. vol 142C. issue 3. 2006-11-08. PMID:16823778. |
brothers and sisters are obligatorily welcomed to the disability community when a person with down syndrome (ds) is part of the family unit. |
2006-11-08 |
2023-08-12 |
Not clear |
| Sally R Shot. Down syndrome: common otolaryngologic manifestations. American journal of medical genetics. Part C, Seminars in medical genetics. vol 142C. issue 3. 2006-11-08. PMID:16838306. |
otolaryngologic or ear, nose, and throat (ent) problems are common in children with down syndrome (ds). |
2006-11-08 |
2023-08-12 |
Not clear |
| William I Cohe. Current dilemmas in Down syndrome clinical care: celiac disease, thyroid disorders, and atlanto-axial instability. American journal of medical genetics. Part C, Seminars in medical genetics. vol 142C. issue 3. 2006-11-08. PMID:16838307. |
this study will discuss our current understanding of celiac disease (cd), thyroid disorders, and atlanto-axial instability, three important areas of medical management in individuals with down syndrome (ds). |
2006-11-08 |
2023-08-12 |
Not clear |
| James H Heller, Gail A Spiridigliozzi, Blythe G Crissman, Jennifer A Sullivan-Saarela, Jennifer S Li, Priya S Kishnan. Clinical trials in children with Down syndrome: issues from a cognitive research perspective. American journal of medical genetics. Part C, Seminars in medical genetics. vol 142C. issue 3. 2006-11-08. PMID:16838317. |
in down syndrome (ds), these research approaches are not well utilized or developed to test new therapies to improve cognitive and/or adaptive function in this population. |
2006-11-08 |
2023-08-12 |
human |
| James H Heller, Gail A Spiridigliozzi, Blythe G Crissman, Jennifer A Sullivan-Saarela, Jennifer S Li, Priya S Kishnan. Clinical trials in children with Down syndrome: issues from a cognitive research perspective. American journal of medical genetics. Part C, Seminars in medical genetics. vol 142C. issue 3. 2006-11-08. PMID:16838317. |
the duke down syndrome research team's program of clinical research of cholinesterase inhibitors for individuals with ds serves as the model application for the identified research principles. |
2006-11-08 |
2023-08-12 |
human |
| George Capone, Parag Goyal, William Ares, Emily Lanniga. Neurobehavioral disorders in children, adolescents, and young adults with Down syndrome. American journal of medical genetics. Part C, Seminars in medical genetics. vol 142C. issue 3. 2006-11-08. PMID:16838318. |
most children with down syndrome (ds) do not have a psychiatric or neurobehavioral disorder. |
2006-11-08 |
2023-08-12 |
Not clear |
| Ebrahim Abdul Shukkur, Atsushi Shimohata, Takumi Akagi, Wenxin Yu, Mika Yamaguchi, Miyuki Murayama, Dehua Chui, Tamaki Takeuchi, Kenji Amano, Karthik Harve Subramhanya, Tsutomu Hashikawa, Haruhiko Sago, Charles J Epstein, Akihiko Takashima, Kazuhiro Yamakaw. Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome. Human molecular genetics. vol 15. issue 18. 2006-11-08. PMID:16891409. |
trisomy 21 or down syndrome (ds) is the most common genetic birth defect associated with mental retardation. |
2006-11-08 |
2023-08-12 |
mouse |
| Atqah Abdul Wahab, Abdulbari Bener, Amy L Sandridge, Georg F Hoffman. The pattern of Down syndrome among children in Qatar: a population-based study. Birth defects research. Part A, Clinical and molecular teratology. vol 76. issue 8. 2006-11-08. PMID:16955492. |
the objective of the present study was to determine the prevalence pattern of down syndrome (ds) in children <5 years of age in the state of qatar. |
2006-11-08 |
2023-08-12 |
Not clear |