| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kirsten Marie Schiøtt, Michael Christiansen, Olav Bjørn Petersen, Tina Lind Sørensen, Niels Uldbjer. The "Consecutive Combined Test"--using double test from week 8 + 0 and nuchal translucency scan, for first trimester screening for Down syndrome. Prenatal diagnosis. vol 26. issue 12. 2007-02-21. PMID:17042034. |
week 12) gives detection rates (dr) for down syndrome (ds) of 80-90% for false positive rates (fpr) of 5%. |
2007-02-21 |
2023-08-12 |
Not clear |
| Ira T Lott, Elizabeth Head, Eric Doran, Jorge Buscigli. Beta-amyloid, oxidative stress and down syndrome. Current Alzheimer research. vol 3. issue 5. 2007-02-20. PMID:17168651. |
down syndrome (ds) provides a model for studying important aspects of alzheimer disease (ad). |
2007-02-20 |
2023-08-12 |
human |
| Jennie Laigaard, Kevin Spencer, Michael Christiansen, Nicholas J Cowans, Severin Olesen Larsen, Bent Norgaard Pedersen, Ulla M Wewe. ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome. Prenatal diagnosis. vol 26. issue 10. 2007-02-16. PMID:16892462. |
a disintegrin and metalloprotease 12 (adam 12) is a glycoprotein synthesised by placenta and it has been shown to be a potential first-trimester maternal serum marker for down syndrome (ds) in two small series. |
2007-02-16 |
2023-08-12 |
Not clear |
| Mostafa Saadat, Parvin Mehdipou. Correlation between IQ and dermatoglyphic indices of Down syndrome patients. Dermatology online journal. vol 12. issue 6. 2007-02-09. PMID:17083905. |
the fingerprint patterns, simian crease, and total ridge count of 41 mild and 61 severe mentally handicapped patients with down syndrome (ds) were compared with a control group of 200 mentally normal individuals. |
2007-02-09 |
2023-08-12 |
Not clear |
| Melanie A Porter, Max Colthear. Global and local processing in Williams syndrome, autism, and Down syndrome: perception, attention, and construction. Developmental neuropsychology. vol 30. issue 3. 2007-02-06. PMID:17083292. |
global and local processing was studied in williams syndrome (ws), autism (as), and down syndrome (ds) using perception, attention, and construction tasks. |
2007-02-06 |
2023-08-12 |
Not clear |
| Meir Lota. Quality physical intervention activity for persons with Down syndrome. TheScientificWorldJournal. vol 7. 2007-02-06. PMID:17221138. |
persons with down syndrome (ds) are at risk for a life of inactivity that can result in a multitude of medical problems including heart and vascular diseases. |
2007-02-06 |
2023-08-12 |
Not clear |
| Sandra M McKay, Rosa M Angulo-Barros. Longitudinal assessment of leg motor activity and sleep patterns in infants with and without Down syndrome. Infant behavior & development. vol 29. issue 2. 2007-02-02. PMID:17138271. |
whether infants with down syndrome (ds) perform leg movements with the same frequency and quality as their typical development (td) counterparts is equivocal. |
2007-02-02 |
2023-08-12 |
Not clear |
| Xianfang Meng, Bin Peng, Jing Shi, Yao Zheng, Hao Chen, Jing Zhang, Lingli Li, Chun Zhan. Effects of overexpression of Sim2 on spatial memory and expression of synapsin I in rat hippocampus. Cell biology international. vol 30. issue 10. 2007-01-31. PMID:16963290. |
the single-minded 2 gene (sim2) plays a crucial role in the mental retardation of down syndrome (ds). |
2007-01-31 |
2023-08-12 |
mouse |
| Lotte Abildgaard, Eva Ellebaek, Göran Gustafsson, Jonas Abrahamsson, Liisa Hovi, Gudmundur Jonmundsson, Bernward Zeller, Henrik Hasl. Optimal treatment intensity in children with Down syndrome and myeloid leukaemia: data from 56 children treated on NOPHO-AML protocols and a review of the literature. Annals of hematology. vol 85. issue 5. 2007-01-25. PMID:16518605. |
children with down syndrome (ds) and myeloid leukaemia have a significantly higher survival rate than other children, but they also experience considerable treatment-related toxicity. |
2007-01-25 |
2023-08-12 |
Not clear |
| Tatyana Adayev, Mo-Chou Chen-Hwang, Noriko Murakami, Rong Wang, Yu-Wen Hwan. MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins. Biochemical and biophysical research communications. vol 351. issue 4. 2007-01-23. PMID:17097615. |
mnb/dyrk1a is a proline-directed serine/threonine kinase implicated in down syndrome (ds). |
2007-01-23 |
2023-08-12 |
human |
| Federico Licastro, Alessandro Marocchi, Silvana Penco, Elisa Porcellini, Domenico Lio, Giada Dogliotti, Massimiliano M Cors. Does Down's syndrome support the homocysteine theory of atherogenesis? Experience in elderly subjects with trisomy 21. Archives of gerontology and geriatrics. vol 43. issue 3. 2007-01-18. PMID:16533539. |
down syndrome (ds) is generally considered as an "atheroma-free model". |
2007-01-18 |
2023-08-12 |
human |
| Susana de la Luna, Xavier Estivil. Cooperation to amplify gene-dosage-imbalance effects. Trends in molecular medicine. vol 12. issue 10. 2007-01-18. PMID:16919501. |
trisomy 21, also known as down syndrome (ds), is a complex developmental disorder that affects many organs, including the brain, heart, skeleton and immune system. |
2007-01-18 |
2023-08-12 |
Not clear |
| Susana de la Luna, Xavier Estivil. Cooperation to amplify gene-dosage-imbalance effects. Trends in molecular medicine. vol 12. issue 10. 2007-01-18. PMID:16919501. |
there is now compelling evidence that the protein products of two genes on chromosome 21, down syndrome candidate region 1 (dscr1) and dual-specificity tyrosine-(y)-phosphorylation regulated kinase 1a (dyrk1a), interact functionally, and that their increased dosage cooperatively leads to dysregulation of the signaling pathways that are controlled by the nuclear factor of activated t cells (nfat) family of transcription factors, with potential consequences for several organs and systems that are affected in ds individuals. |
2007-01-18 |
2023-08-12 |
Not clear |
| Stylianos E Antonarakis, Charles J Epstei. The challenge of Down syndrome. Trends in molecular medicine. vol 12. issue 10. 2007-01-18. PMID:16935027. |
down syndrome (ds) has been recognized as a clinical entity for about 150 years, but it is only recently that there has been hope for the possibility to understand its pathogenesis and to use this information to devise approaches for the prevention and treatment of its numerous features. |
2007-01-18 |
2023-08-12 |
Not clear |
| Süreyya Savaşan, Steven Buck, Susana C Raimondi, David L Becton, Howard Weinstein, Myron Chang, Yaddanapudi Ravindranat. CD36 (thrombospondin receptor) expression in childhood acute megakaryoblastic leukemia: in vitro drug sensitivity and outcome. Leukemia & lymphoma. vol 47. issue 10. 2007-01-17. PMID:17071479. |
the outcome for children with acute megakaryoblastic leukemia (amkl) remains poor, except for cases associated with down syndrome (ds). |
2007-01-17 |
2023-08-12 |
Not clear |
| A S Paul van Trotsenburg, Marlies J E Kempers, Erik Endert, Jan G P Tijssen, Jan J M de Vijlder, Thomas Vulsm. Trisomy 21 causes persistent congenital hypothyroidism presumably of thyroidal origin. Thyroid : official journal of the American Thyroid Association. vol 16. issue 7. 2007-01-16. PMID:16889491. |
lowered neonatal plasma thyroxine (t(4)) and mildly elevated thyrotropin concentrations together with developmental benefits from neonatally started t(4) treatment in a randomized clinical trial demonstrated down syndrome (ds) neonates to be mildly hypothyroid, at least during their first weeks of life. |
2007-01-16 |
2023-08-12 |
Not clear |
| Mensuda Hasanhodzić, Husref Tahirović, Ljerka Lukina. Down Syndrome and thyroid gland. Bosnian journal of basic medical sciences. vol 6. issue 3. 2007-01-09. PMID:16995846. |
down syndrome (ds) or trisomy 21 (t21) is the most frequent and the best known malformation syndrome associated with mental deficiency that appears in human,. |
2007-01-09 |
2023-08-12 |
human |
| Mensuda Hasanhodzić, Husref Tahirović, Ljerka Lukina. Down Syndrome and thyroid gland. Bosnian journal of basic medical sciences. vol 6. issue 3. 2007-01-09. PMID:16995846. |
numerous researchers noted thyroid disorders in people with down syndrome but, clinical symptoms of thyroid dysfunction are difficult to separate from ds phenotype. |
2007-01-09 |
2023-08-12 |
human |
| Susan Blaser, Evan J Propst, Daniel Martin, Annette Feigenbaum, Adrian L James, Patrick Shannon, Blake C Papsi. Inner ear dysplasia is common in children with Down syndrome (trisomy 21). The Laryngoscope. vol 116. issue 12. 2007-01-09. PMID:17146381. |
middle and external ear anomalies are well recognized in down syndrome (ds, trisomy 21). |
2007-01-09 |
2023-08-12 |
Not clear |
| Patricia Opazo, Katherine Saud, Michelle de Saint Pierre, Ana María Cárdenas, David D Allen, Juan Segura-Aguilar, Raúl Caviedes, Pablo Caviede. Knockdown of amyloid precursor protein normalizes cholinergic function in a cell line derived from the cerebral cortex of a trisomy 16 mouse: An animal model of down syndrome. Journal of neuroscience research. vol 84. issue 6. 2007-01-04. PMID:16941497. |
we have generated immortal neuronal cell lines from normal and trisomy 16 (ts16) mice, a model for down syndrome (ds). |
2007-01-04 |
2023-08-12 |
mouse |