| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alberto C S Cost. An assessment of the vestibulo-ocular reflex (VOR) in persons with Down syndrome. Experimental brain research. vol 214. issue 2. 2012-06-26. PMID:21842192. |
down syndrome (ds), the most common genetically defined cause of intellectual disability, is the phenotypic consequence of a supernumerary chromosome 21. |
2012-06-26 |
2023-08-12 |
human |
| Alberto C S Cost. An assessment of optokinetic nystagmus (OKN) in persons with Down syndrome. Experimental brain research. vol 214. issue 3. 2012-06-22. PMID:21842408. |
down syndrome (ds), the most common genetically defined cause of intellectual disability, is the phenotypic consequence of a supernumerary chromosome 21. |
2012-06-22 |
2023-08-12 |
human |
| Philip Zachariah, Margaret Ruttenber, Eric A F Simõe. Down syndrome and hospitalizations due to respiratory syncytial virus: a population-based study. The Journal of pediatrics. vol 160. issue 5. 2012-06-20. PMID:22177993. |
to assess the risk estimates for respiratory syncytial virus (rsv) hospitalization in children with down syndrome (ds) and the clinical features and severity of rsv lower respiratory tract infection (lrti) in hospitalized children. |
2012-06-20 |
2023-08-12 |
Not clear |
| Yeepay Wuang, Chwen-Yng S. Patterns of participation and enjoyment in adolescents with Down syndrome. Research in developmental disabilities. vol 33. issue 3. 2012-06-20. PMID:22245731. |
this study aimed to determine participation and enjoyment in young people with down syndrome (ds) in taiwan and to assess how participation varies across gender, cognitive, and motor function variables. |
2012-06-20 |
2023-08-12 |
Not clear |
| Ananya Mitra, Martina Blank, Daniel V Madiso. Developmentally altered inhibition in Ts65Dn, a mouse model of Down syndrome. Brain research. vol 1440. 2012-06-20. PMID:22284618. |
we studied the development of gaba-mediated synaptic inhibition in the ca1 region of the hippocampus in ts65dn mice, a model system for down syndrome (ds). |
2012-06-20 |
2023-08-12 |
mouse |
| P King, R Tullo. Management of pulmonary hypertension and Down syndrome. International journal of clinical practice. Supplement. issue 174. 2012-06-19. PMID:22171818. |
down syndrome (ds) is strongly associated with pulmonary hypertension, but there are many causes requiring a multi-disciplinary approach to the problem. |
2012-06-19 |
2023-08-12 |
Not clear |
| Hiroshi Koga, Kenichi Miyako, Naohiro Suga, Tomoko Hidaka, Noboru Takahash. Improving circulatory disturbance in transient abnormal myelopoiesis. Journal of pediatric hematology/oncology. vol 34. issue 4. 2012-06-18. PMID:22134612. |
transient abnormal myelopoiesis (tam) in neonates with down syndrome (ds) is characterized by circulating blast cells in the blood. |
2012-06-18 |
2023-08-12 |
Not clear |
| Olivia Sheppard, Florian Plattner, Anna Rubin, Amy Slender, Jacqueline M Linehan, Sebastian Brandner, Victor L J Tybulewicz, Elizabeth M C Fisher, Frances K Wisema. Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiology of aging. vol 33. issue 4. 2012-06-15. PMID:21843906. |
down syndrome (ds) results from trisomy of human chromosome 21 (hsa21) and is associated with an increased risk of alzheimer's disease (ad). |
2012-06-15 |
2023-08-12 |
mouse |
| Constance Chace, Deborah Pang, Catherine Weng, Alexis Temkin, Simon Lax, Wayne Silverman, Warren Zigman, Michel Ferin, Joseph H Lee, Benjamin Tycko, Nicole Schup. Variants in CYP17 and CYP19 cytochrome P450 genes are associated with onset of Alzheimer's disease in women with down syndrome. Journal of Alzheimer's disease : JAD. vol 28. issue 3. 2012-06-15. PMID:22057025. |
women with down syndrome (ds) have early onset and high risk for alzheimer's disease (ad). |
2012-06-15 |
2023-08-12 |
Not clear |
| Caroline I Magyar, Vincent Pandolfi, Charles A Dil. An initial evaluation of the Social Communication Questionnaire for the assessment of autism spectrum disorders in children with Down syndrome. Journal of developmental and behavioral pediatrics : JDBP. vol 33. issue 2. 2012-06-14. PMID:22267105. |
this study investigated the psychometric properties of the social communication questionnaire (scq) in a sample of children with down syndrome (ds), many of whom had a co-occurring autism spectrum disorder (asd). |
2012-06-14 |
2023-08-12 |
Not clear |
| Catriona Hippman, Angela Inglis, Jehannine Austi. What is a "balanced" description? Insight from parents of individuals with down syndrome. Journal of genetic counseling. vol 21. issue 1. 2012-06-13. PMID:22183831. |
genetic counselors and parents of individuals with down syndrome (ds) agree that descriptions of ds in prenatal settings should be "balanced." |
2012-06-13 |
2023-08-12 |
human |
| Martha Millan Sanchez, Sietske N Heyn, Devsmita Das, Sarah Moghadam, Kara J Martin, Ahmad Saleh. Neurobiological elements of cognitive dysfunction in down syndrome: exploring the role of APP. Biological psychiatry. vol 71. issue 5. 2012-06-12. PMID:21945306. |
down syndrome (ds) is the most common cause of cognitive dysfunction in children. |
2012-06-12 |
2023-08-12 |
mouse |
| S Lanfranchi, A Baddeley, S Gathercole, R Vianell. Working memory in Down syndrome: is there a dual task deficit? Journal of intellectual disability research : JIDR. vol 56. issue 2. 2012-06-11. PMID:21726323. |
recent studies have shown that individuals with down syndrome (ds) are poorer than controls in performing verbal and visuospatial dual tasks. |
2012-06-11 |
2023-08-12 |
Not clear |
| Bruna Lancia Zampieri, Joice Matos Biselli, Eny Maria Goloni-Bertollo, Hélio Vannucchi, Valdemir Melechco Carvalho, José Antônio Cordeiro, Erika Cristina Pavarin. Maternal risk for Down syndrome is modulated by genes involved in folate metabolism. Disease markers. vol 32. issue 2. 2012-06-11. PMID:22377700. |
studies have shown that the maternal risk for down syndrome (ds) may be modulated by alterations in folate metabolism. |
2012-06-11 |
2023-08-12 |
Not clear |
| Tarik F Haydar, Roger H Reeve. Trisomy 21 and early brain development. Trends in neurosciences. vol 35. issue 2. 2012-06-04. PMID:22169531. |
trisomy for human chromosome 21 (hsa21) results in down syndrome (ds). |
2012-06-04 |
2023-08-12 |
mouse |
| Lizbeth H Finestack, Meghan Palmer, Leonard Abbedut. Macrostructural narrative language of adolescents and young adults with Down syndrome or fragile X syndrome. American journal of speech-language pathology. vol 21. issue 1. 2012-05-29. PMID:22049405. |
to gain a better understanding of language abilities, the expressive macrostructural narrative language abilities of verbally expressive adolescents and young adults with down syndrome (ds) and those with fragile x syndrome (fxs) were examined. |
2012-05-29 |
2023-08-12 |
Not clear |
| Vinciane Régnier, Jean-Marie Billard, Sapna Gupta, Brigitte Potier, Stéphanie Woerner, Evelyne Paly, Aurélie Ledru, Sabrina David, Sabrina Luilier, Jean-Charles Bizot, Guido Vacano, Jan P Kraus, David Patterson, Warren D Kruger, Jean M Delabar, Jaqueline Londo. Brain phenotype of transgenic mice overexpressing cystathionine β-synthase. PloS one. vol 7. issue 1. 2012-05-29. PMID:22253703. |
the cystathionine β-synthase (cbs) gene, located on human chromosome 21q22.3, is a good candidate for playing a role in the down syndrome (ds) cognitive profile: it is overexpressed in the brain of individuals with ds, and it encodes a key enzyme of sulfur-containing amino acid (saa) metabolism, a pathway important for several brain physiological processes. |
2012-05-29 |
2023-08-12 |
mouse |
| Gustavo Henrique Marucci, Bruna Lancia Zampieri, Joice Matos Biselli, Sendi Valentin, Eny Maria Goloni Bertollo, Marcos Nogueira Eberlin, Renato Haddad, Maria Francesca Riccio, Hélio Vannucchi, Valdemir Melechco Carvalho, Erika Cristina Pavarin. Polymorphism C1420T of Serine hydroxymethyltransferase gene on maternal risk for Down syndrome. Molecular biology reports. vol 39. issue 3. 2012-05-25. PMID:21687976. |
recent researches have investigated the factors that determine the maternal risk for down syndrome (ds) in young woman. |
2012-05-25 |
2023-08-12 |
Not clear |
| Susanne Haemmerling, Wolfgang Behnisch, Tobias Doerks, Jan O Korbel, Peer Bork, Ute Moog, Sabine Hentze, Ute Grasshoff, Michael Bonin, Olaf Rieß, Johannes W G Janssen, Anna Jauch, Claus R Bartram, Dirk Reinhardt, Karin A Koch, Obul R Bandapalli, Andreas E Kulozi. A 15q24 microdeletion in transient myeloproliferative disease (TMD) and acute megakaryoblastic leukaemia (AMKL) implicates PML and SUMO3 in the leukaemogenesis of TMD/AMKL. British journal of haematology. vol 157. issue 2. 2012-05-22. PMID:22296450. |
transient myeloproliferative disorder (tmd) of the newborn and acute megakaryoblastic leukaemia (amkl) in children with down syndrome (ds) represent paradigmatic models of leukaemogenesis. |
2012-05-22 |
2023-08-12 |
Not clear |
| Alexander M Kleschevnikov, Pavel V Belichenko, Jessica Gall, Lizzy George, Rachel Nosheny, Michael T Maloney, Ahmad Salehi, William C Moble. Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome. Neurobiology of disease. vol 45. issue 2. 2012-05-18. PMID:22062771. |
cognitive impairment in down syndrome (ds) involves the hippocampus. |
2012-05-18 |
2023-08-12 |
mouse |