| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Angela Inglis, Catriona Hippman, Jehannine C Austi. Prenatal testing for Down syndrome: the perspectives of parents of individuals with Down syndrome. American journal of medical genetics. Part A. vol 158A. issue 4. 2012-07-30. PMID:22354662. |
this survey-based study was designed in collaboration with parents of individuals with ds and the british columbia-based lower mainland down syndrome society (lmdss). |
2012-07-30 |
2023-08-12 |
human |
| Eduardo Martínez-Morillo, Belén Prieto García, Francisco Moreno Calvo, Francisco V Alvare. Evaluation of population parameters and mathematical strategies for the calculation of prenatal risk of Down syndrome in the first trimester of pregnancy. Prenatal diagnosis. vol 32. issue 3. 2012-07-27. PMID:22430720. |
to evaluate the population parameters applied to the calculation of risk for down syndrome (ds) in the first trimester screening (fts) and the comparison of performance obtained including or excluding maternal age from the mathematical algorithm. |
2012-07-27 |
2023-08-12 |
Not clear |
| Yuan Kang, Xinran Dong, Qiongjie Zhou, Ying Zhang, Yan Cheng, Rong Hu, Cuihong Su, Hong Jin, Xiaohui Liu, Duan Ma, Weidong Tian, Xiaotian L. Identification of novel candidate maternal serum protein markers for Down syndrome by integrated proteomic and bioinformatic analysis. Prenatal diagnosis. vol 32. issue 3. 2012-07-27. PMID:22430729. |
this study aimed to identify candidate protein biomarkers from maternal serum for down syndrome (ds) by integrated proteomic and bioinformatics analysis. |
2012-07-27 |
2023-08-12 |
Not clear |
| Chiarella Sforza, Fadil Elamin, Claudia Dellavia, Riccardo Rosati, Gianluigi Lodetti, Andrea Mapelli, Virgilio Ferruccio Ferrari. Morphometry of the orbital region soft tissues in Down syndrome. The Journal of craniofacial surgery. vol 23. issue 1. 2012-07-24. PMID:22337407. |
the orbital region of subjects with down syndrome (ds) has been scanty described so far. |
2012-07-24 |
2023-08-12 |
human |
| Carla Lintas, Roberto Sacco, Antonio M Persic. Genome-wide expression studies in autism spectrum disorder, Rett syndrome, and Down syndrome. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21130877. |
though different in their aetiology, autism spectrum disorder (asd), rett syndrome (rtt) and down syndrome (ds) are three neurodevelopmental disorders sharing significant clinical and neuropathological overlaps. |
2012-07-23 |
2023-08-12 |
Not clear |
| Gregory L Jackson, Dorothy M Sendelbach, Brooke Rambally, M Denise Manning, William D Engl. Circulating blasts and associated hematologic disorders in neonates with Down syndrome. American journal of perinatology. vol 29. issue 4. 2012-07-23. PMID:21809264. |
we analyzed complete blood count (cbc) data obtained from neonates with down syndrome (ds) in a primarily hispanic population over a 10-year period to determine the incidence of hematologic abnormalities and the relationship of abnormalities to the presence of circulating blasts (cb). |
2012-07-23 |
2023-08-12 |
Not clear |
| Stamatis Agiovlasitis, Robert W Motl, John T Foley, Bo Fernhal. Prediction of energy expenditure from wrist accelerometry in people with and without Down syndrome. Adapted physical activity quarterly : APAQ. vol 29. issue 2. 2012-07-23. PMID:22467836. |
this study examined the relationship between energy expenditure and wrist accelerometer output during walking in persons with and without down syndrome (ds). |
2012-07-23 |
2023-08-12 |
Not clear |
| Carol A Lunney, Harold L Kleinert, James E Ferguson, Lynn Campbel. Effectively training pediatric residents to deliver diagnoses of Down syndrome. American journal of medical genetics. Part A. vol 158A. issue 2. 2012-07-20. PMID:22246816. |
physicians and parents report a need for pediatricians to have additional training in delivering a diagnosis of down syndrome (ds). |
2012-07-20 |
2023-08-12 |
human |
| Beth A Smith, Nicholas Stergiou, Beverly D Ulric. Patterns of gait variability across the lifespan in persons with and without down syndrome. Journal of neurologic physical therapy : JNPT. vol 35. issue 4. 2012-07-19. PMID:22052133. |
greater gait variability has been observed in persons with down syndrome (ds). |
2012-07-19 |
2023-08-12 |
Not clear |
| Matthew D Howell, Paul E Gottschal. Altered synaptic marker abundance in the hippocampal stratum oriens of Ts65Dn mice is associated with exuberant expression of versican. ASN neuro. vol 4. issue 1. 2012-07-18. PMID:22225533. |
ds (down syndrome), resulting from trisomy of chromosome 21, is the most common cause of genetic mental retardation; however, the molecular mechanisms underlying the cognitive deficits are poorly understood. |
2012-07-18 |
2023-08-12 |
mouse |
| Bozena Mazur-Kolecka, Adam Golabek, Elizabeth Kida, Ausma Rabe, Yu-Wen Hwang, Tatyana Adayev, Jerzy Wegiel, Michael Flory, Wojciech Kaczmarski, Elaine Marchi, Janusz Frackowia. Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice. Journal of neuroscience research. vol 90. issue 5. 2012-07-16. PMID:22252917. |
overexpression of dual-specificity tyrosine-(y)-phosphorylation-regulated kinase 1a (dyrk1a), encoded by a gene located in the down syndrome (ds) critical region, is considered a major contributor to developmental abnormalities in ds. |
2012-07-16 |
2023-08-12 |
mouse |
| Cheng-Juan Sun, Li-Yu Yan, Wei Wang, Song Yu, Xin Wang, Wei-Yuan Zhan. Proteomic analysis of the alteration of protein expression in the placenta of Down syndrome. Chinese medical journal. vol 124. issue 22. 2012-07-12. PMID:22340234. |
down syndrome (ds) is the most common form of human aneuploidy, and there is no effective therapy for the chromosomal abnormalities. |
2012-07-12 |
2023-08-12 |
human |
| Giovanna Cenini, Amy L S Dowling, Tina L Beckett, Eugenio Barone, Cesare Mancuso, Michael Paul Murphy, Harry Levine, Ira T Lott, Frederick A Schmitt, D Allan Butterfield, Elizabeth Hea. Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome. Biochimica et biophysica acta. vol 1822. issue 2. 2012-07-10. PMID:22009041. |
down syndrome (ds) is the most common genetic cause of intellectual disability in children, and the number of adults with ds reaching old age is increasing. |
2012-07-10 |
2023-08-12 |
Not clear |
| Md Mahiuddin Ahmed, Xiaolu Sturgeon, Misoo Ellison, Muriel T Davisson, Katheleen J Gardine. Loss of correlations among proteins in brains of the Ts65Dn mouse model of down syndrome. Journal of proteome research. vol 11. issue 2. 2012-07-10. PMID:22214338. |
the ts65dn mouse model of down syndrome (ds) is trisomic for orthologs of 88 of 161 classical protein coding genes present on human chromosome 21 (hsa21). |
2012-07-10 |
2023-08-12 |
mouse |
| Ping Wu, Qi-jie Li, Zheng-liang Xia, Fa-qiang Zhang, Lin-lin Yue, Qing-ying Chen, Hong Wang, Chun-yuan Fan, Qing-jie Xi. [Detecting Down syndrome with a novel dual-color competitive quantitative fluorescent polymerase chain reaction method]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 29. issue 1. 2012-07-10. PMID:22311490. |
to develop a rapid method for the detection of down syndrome (ds) using dual-color competitive quantitative fluorescent polymerase chain reaction (dcc-qf-pcr), and to assess its feasibility for the prenatal diagnosis of down syndrome. |
2012-07-10 |
2023-08-12 |
Not clear |
| Ahmad R Sedaghat, Renee B Flax-Goldenberg, Bob W Gayler, George T Capone, Stacey L Ishma. A case-control comparison of lingual tonsillar size in children with and without Down syndrome. The Laryngoscope. vol 122. issue 5. 2012-07-10. PMID:22374875. |
lingual tonsillar hypertrophy is a common cause of persistent obstructive sleep apnea following adenotonsillectomy in the pediatric population and may be more prevalent in patients with down syndrome (ds). |
2012-07-10 |
2023-08-12 |
Not clear |
| Qing-Shan Xue, Wolfgang J Strei. Microglial pathology in Down syndrome. Acta neuropathologica. vol 122. issue 4. 2012-07-09. PMID:21847625. |
subjects with down syndrome (ds) inevitably develop histopathological features pathognomonic of alzheimer's disease (ad), and ds can therefore be considered a human model of ad. |
2012-07-09 |
2023-08-12 |
human |
| Chantal J M Broers, Reinoud J B J Gemke, Michel E Weijerman, Koen F van der Sluijs, A Marceline van Furt. Increased pro-inflammatory cytokine production in Down Syndrome children upon stimulation with live influenza A virus. Journal of clinical immunology. vol 32. issue 2. 2012-07-09. PMID:22170315. |
children with down syndrome (ds) have an increased susceptibility to infections, due to altered humoral and/or cellular immunity. |
2012-07-09 |
2023-08-12 |
Not clear |
| Helma B M Van Gameren-Oosterom, Paula Van Dommelen, Anne Marie Oudesluys-Murphy, Simone E Buitendijk, Stef Van Buuren, Jacobus P Van Wouw. Healthy growth in children with Down syndrome. PloS one. vol 7. issue 2. 2012-06-29. PMID:22363551. |
to provide cross-sectional height and head circumference (hc) references for healthy dutch children with down syndrome (ds), while considering the influence of concomitant disorders on their growth, and to compare growth between children with ds and children from the general population. |
2012-06-29 |
2023-08-12 |
Not clear |
| Samuel W Moore, Monique G Zaah. Intronic RET gene variants in Down syndrome-associated Hirschsprung disease in an African population. Journal of pediatric surgery. vol 47. issue 2. 2012-06-28. PMID:22325379. |
clinical association between hirschsprung disease (hd) and down syndrome (ds) is well established. |
2012-06-28 |
2023-08-12 |
Not clear |