| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leslie A Mahler, Harrison N Jone. Intensive treatment of dysarthria in two adults with Down syndrome. Developmental neurorehabilitation. vol 15. issue 1. 2012-05-17. PMID:22256834. |
this study investigated the impact of an established behavioural dysarthria treatment on acoustic and perceptual measures of speech in two adults with down syndrome (ds) and dysarthria to obtain preliminary measures of treatment effect, effect size and treatment feasibility. |
2012-05-17 |
2023-08-12 |
Not clear |
| Eli Carmeli, Claudette Ariav, Tamar Bar-Yossef, Ran Levy, Bita Ima. Movement skills of younger versus older adults with and without Down syndrome. Research in developmental disabilities. vol 33. issue 1. 2012-05-14. PMID:22093661. |
adults with down syndrome (ds) are often physically inactive, which may accelerate the onset of disease and aging symptoms. |
2012-05-14 |
2023-08-12 |
Not clear |
| Megan A Hattier, Johnny L Matson, Brian Belva, Ali Kozlowsk. The effects of diagnostic group and gender on challenging behaviors in infants and toddlers with cerebral palsy, Down syndrome or seizures. Research in developmental disabilities. vol 33. issue 1. 2012-05-14. PMID:22093672. |
for that reason, the current study's aim was to analyze problem behavior deficits in infants and toddlers diagnosed with cerebral palsy (cp), down syndrome (ds), and a history of seizures/seizure disorder. |
2012-05-14 |
2023-08-12 |
Not clear |
| P Venuti, S de Falco, G Esposito, M Zaninelli, Marc H Bornstei. Maternal functional speech to children: a comparison of autism spectrum disorder, Down syndrome, and typical development. Research in developmental disabilities. vol 33. issue 2. 2012-05-08. PMID:22119699. |
the purposes of the present study were to compare maternal functional language directed to children with two developmental disabilities--autism spectrum disorder (asd) and down syndrome (ds)--with td children and to investigate relations of maternal functional language with child language skills. |
2012-05-08 |
2023-08-12 |
human |
| Ariel Tenenbaum, Maor Chavkin, Isaiah D Wexler, Maya Korem, Joav Merric. Morbidity and hospitalizations of adults with Down syndrome. Research in developmental disabilities. vol 33. issue 2. 2012-05-08. PMID:22137940. |
over the last decade a significant increase in the life expectancy of people with down syndrome (ds) has been observed, which has caused a higher incidence of morbidity as they age. |
2012-05-08 |
2023-08-12 |
Not clear |
| Adam Johns, Judi Homewood, Richard Stevenson, Alan Taylo. Implicit and explicit olfactory memory in people with and without Down syndrome. Research in developmental disabilities. vol 33. issue 2. 2012-05-08. PMID:22138497. |
this study examined differences in implicit and explicit memory performance between people with down syndrome (ds), their siblings, children matched on mental age, and university undergraduates, using olfactory stimuli. |
2012-05-08 |
2023-08-12 |
human |
| Eli Vakil, Hefziba Lifshitz-Zehav. Solving the Raven Progressive Matrices by adults with intellectual disability with/without Down syndrome: different cognitive patterns as indicated by eye-movements. Research in developmental disabilities. vol 33. issue 2. 2012-05-08. PMID:22186631. |
twenty-three adults with non-specific intellectual disability (nsid), 15 adults with down syndrome (ds) and 35 children with td matched for mental age, participated. |
2012-05-08 |
2023-08-12 |
human |
| Mehrdad Faizi, Patrick L Bader, Christine Tun, Angelo Encarnacion, Alexander Kleschevnikov, Pavel Belichenko, Nay Saw, Matthew Priestley, Richard W Tsien, William C Mobley, Mehrdad Shamlo. Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer. Neurobiology of disease. vol 43. issue 2. 2012-05-07. PMID:21527343. |
down syndrome (ds) is the most prevalent form of mental retardation caused by genetic abnormalities in humans. |
2012-05-07 |
2023-08-12 |
mouse |
| Patti Berg, Tiffany Becker, Andrew Martian, Kimberly Danielle Primrose, Julie Winge. Motor control outcomes following Nintendo Wii use by a child with Down syndrome. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 24. issue 1. 2012-05-03. PMID:22207475. |
the purpose of this work was to examine motor outcomes following an 8-week intervention period of family-supported nintendo wii use by a child with a diagnosis of down syndrome (ds). |
2012-05-03 |
2023-08-12 |
Not clear |
| Pradeep Raut, Bhavani Sriram, Annie Yeoh, Karen Y M Hee, Sok Bee Lim, Mary L Danie. High prevalence of hearing loss in Down syndrome at first year of life. Annals of the Academy of Medicine, Singapore. vol 40. issue 11. 2012-05-02. PMID:22206065. |
infants with down syndrome (ds) are at higher risk of hearing loss (hl). |
2012-05-02 |
2023-08-12 |
Not clear |
| Yehudit Birger, Shai Izrael. DYRK1A in Down syndrome: an oncogene or tumor suppressor? The Journal of clinical investigation. vol 122. issue 3. 2012-04-30. PMID:22354166. |
children with down syndrome (ds) have a markedly increased risk of developing acute megakaryoblastic leukemia (amkl) and acute lymphoblastic leukemia compared with that of children without ds. |
2012-04-30 |
2023-08-12 |
mouse |
| Sébastien Malinge, Meghan Bliss-Moreau, Gina Kirsammer, Lauren Diebold, Timothy Chlon, Sandeep Gurbuxani, John D Crispin. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. The Journal of clinical investigation. vol 122. issue 3. 2012-04-30. PMID:22354171. |
individuals with down syndrome (ds; also known as trisomy 21) have a markedly increased risk of leukemia in childhood but a decreased risk of solid tumors in adulthood. |
2012-04-30 |
2023-08-12 |
mouse |
| Chunhong Liu, Pavel V Belichenko, Li Zhang, Dawei Fu, Alexander M Kleschevnikov, Antonio Baldini, Stylianos E Antonarakis, William C Mobley, Y Eugene Y. Mouse models for Down syndrome-associated developmental cognitive disabilities. Developmental neuroscience. vol 33. issue 5. 2012-04-16. PMID:21865664. |
down syndrome (ds) is mainly caused by the presence of an extra copy of human chromosome 21 (hsa21) and is a leading genetic cause for developmental cognitive disabilities in humans. |
2012-04-16 |
2023-08-12 |
mouse |
| Lina Chakrabarti, Joseph Scafidi, Vittorio Gallo, Tarik F Hayda. Environmental enrichment rescues postnatal neurogenesis defect in the male and female Ts65Dn mouse model of Down syndrome. Developmental neuroscience. vol 33. issue 5. 2012-04-16. PMID:21865665. |
down syndrome (ds), the most frequent genetic cause of intellectual disability and developmental delay, results from impaired neural stem cell proliferation and differentiation. |
2012-04-16 |
2023-08-12 |
mouse |
| C Baamonde, C Martínez-Cué, J Flórez, M Diersse. G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model. Developmental neuroscience. vol 33. issue 5. 2012-04-16. PMID:21865666. |
individuals with down syndrome (ds) present cognitive deficits that can be improved by early implementation of special care programs. |
2012-04-16 |
2023-08-12 |
mouse |
| Alberto C S Cost. On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down syndrome. Developmental neuroscience. vol 33. issue 5. 2012-04-16. PMID:21893967. |
down syndrome (ds) is the phenotypic consequence of trisomy 21 and is the most common genetically defined cause of intellectual disability. |
2012-04-16 |
2023-08-12 |
mouse |
| Jennifer Keck-Wherley, Deepak Grover, Sharmistha Bhattacharyya, Xiufen Xu, Derek Holman, Eric D Lombardini, Ranjana Verma, Roopa Biswas, Zygmunt Galdzick. Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes. Developmental neuroscience. vol 33. issue 5. 2012-04-16. PMID:22042248. |
down syndrome (ds; trisomy 21) is one of the most common genetic causes of intellectual disability, which is attributed to triplication of genes located on chromosome 21. |
2012-04-16 |
2023-08-12 |
mouse |
| Seon Sook Kim, Yohan Oh, Kwang Chul Chung, Su Ryeon Se. Protein kinase A phosphorylates Down syndrome critical region 1 (RCAN1). Biochemical and biophysical research communications. vol 418. issue 4. 2012-04-16. PMID:22293192. |
the down syndrome critical region 1 (dscr1) gene encodes a regulator of the calcineurin 1 (rcan1) protein, and the elevated levels of rcan1 are associated with alzheimer's disease (ad) and down syndrome (ds). |
2012-04-16 |
2023-08-12 |
Not clear |
| Samantha L Deitz, Randall J Rope. Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice. Genetics. vol 189. issue 4. 2012-04-11. PMID:21926299. |
individuals with full or partial trisomy 21 (ts21) present with clinical features collectively referred to as down syndrome (ds), although ds phenotypes vary in incidence and severity between individuals. |
2012-04-11 |
2023-08-12 |
mouse |
| Samantha L Deitz, Randall J Rope. Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice. Genetics. vol 189. issue 4. 2012-04-11. PMID:21926299. |
the ts1rhr mouse model is trisomic for 33 genes (the "down syndrome critical region" or dscr) hypothesized to be responsible for many clinical ds features, including craniofacial dysmorphology with a small mandible. |
2012-04-11 |
2023-08-12 |
mouse |