| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antonia M W Coppus, Maaike Schuur, Jeanet Vergeer, A Cecile J W Janssens, Ben A Oostra, Marcel M Verbeek, Cornelia M van Duij. Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome. Neurobiology of aging. vol 33. issue 9. 2012-11-29. PMID:21958962. |
in down syndrome (ds), alzheimer's disease is assumed to be caused by the triplication and overexpression of the gene for amyloid precursor protein (app), located on chromosome 21. |
2012-11-29 |
2023-08-12 |
Not clear |
| Adedayo Omobolanle Adio, Samuel Otabor Wajuihia. Ophthalmic manifestations of children with Down syndrome in Port Harcourt, Nigeria. Clinical ophthalmology (Auckland, N.Z.). vol 6. 2012-11-28. PMID:23185113. |
the aim of this study was to provide a profile of oculo-visual anomalies in children with down syndrome (ds) in port harcourt, nigeria. |
2012-11-28 |
2023-08-12 |
Not clear |
| April D Sorrell, Todd A Alonzo, Joanne M Hilden, Robert B Gerbing, Thomas W Loew, Lois Hathaway, Dorothy Barnard, Jeffrey W Taub, Yaddanapudi Ravindranath, Franklin O Smith, Robert J Arceci, William G Woods, Alan S Gami. Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group trial A2971: a report from the Children's Oncology Group. Cancer. vol 118. issue 19. 2012-11-26. PMID:22392565. |
children who are treated for myeloid leukemia associated with down syndrome (ds) experience superior survival compared with children who have myeloid leukemia without ds. |
2012-11-26 |
2023-08-12 |
Not clear |
| Nathan Cramer, Zygmunt Galdzick. From abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome. Neural plasticity. vol 2012. 2012-11-20. PMID:22848844. |
down syndrome (ds) is caused by the overexpression of genes on triplicated regions of human chromosome 21 (hsa21). |
2012-11-20 |
2023-08-12 |
mouse |
| Debarati Ghosh, Swagata Sinha, Anindita Chatterjee, Krishnadas Nandagopa. Discerning non-disjunction in Down syndrome patients by means of GluK1-(AGAT)(n) and D21S2055-(GATA)(n) microsatellites on chromosome 21. Indian journal of human genetics. vol 18. issue 2. 2012-11-20. PMID:23162297. |
down syndrome (ds), the leading genetic cause of mental retardation, stems from non-disjunction of chromosome 21. |
2012-11-20 |
2023-08-12 |
Not clear |
| Elaine Fung, Manisha Witmans, Monty Ghosh, Dominic Cave, Hamdy El-Haki. Upper airway findings in children with Down syndrome on sleep nasopharyngoscopy: case-control study. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale. vol 41. issue 2. 2012-11-06. PMID:22569015. |
to identify the pattern of upper airway endoscopic findings in down syndrome (ds) children with sleep-disordered breathing (sdb) spectrum. |
2012-11-06 |
2023-08-12 |
Not clear |
| Chantal J M Broers, Reinoud J B J Gemke, Michel E Weijerman, Dirk-J Kuik, Ingrid M W van Hoogstraten, A Marceline van Furt. Frequency of lower respiratory tract infections in relation to adaptive immunity in children with Down syndrome compared to their healthy siblings. Acta paediatrica (Oslo, Norway : 1992). vol 101. issue 8. 2012-11-05. PMID:22548641. |
children with down syndrome (ds) experience respiratory tract infections (rtis) more frequently than healthy children. |
2012-11-05 |
2023-08-12 |
Not clear |
| Eduardo Martínez-Morillo, Chan-Kyung J Cho, Andrei P Drabovich, Julie L V Shaw, Antoninus Soosaipillai, Eleftherios P Diamandi. Development of a multiplex selected reaction monitoring assay for quantification of biochemical markers of down syndrome in amniotic fluid samples. Journal of proteome research. vol 11. issue 7. 2012-11-05. PMID:22681384. |
down syndrome (ds) is one of the most common chromosomal abnormalities affecting about 1 of every 700 fetuses. |
2012-11-05 |
2023-08-12 |
Not clear |
| Beatriz Gaete, Cecilia Mellado, Marta Hernánde. [Prevalence of neurological disorders among children with Down syndrome]. Revista medica de Chile. vol 140. issue 2. 2012-10-31. PMID:22739951. |
neurological disturbances are common problems in children with down syndrome (ds). |
2012-10-31 |
2023-08-12 |
Not clear |
| Hyunkyung Choi, Marcia Van Riper, Suzanne Thoyr. Decision making following a prenatal diagnosis of Down syndrome: an integrative review. Journal of midwifery & women's health. vol 57. issue 2. 2012-10-24. PMID:22432488. |
prenatal screening for down syndrome (ds) is a routine part of prenatal care in many countries, and there is growing interest in the choices women make following a prenatal diagnosis of ds. |
2012-10-24 |
2023-08-12 |
Not clear |
| Bruna Lancia Zampieri, Joice Matos Biselli, Eny Maria Goloni-Bertollo, Erika Cristina Pavarin. BHMT G742A and MTHFD1 G1958A polymorphisms and Down syndrome risk in the Brazilian population. Genetic testing and molecular biomarkers. vol 16. issue 6. 2012-10-22. PMID:22339736. |
attempts to elucidate the causes of down syndrome (ds) have analyzed the relationship between polymorphism in folate metabolism and ds. |
2012-10-22 |
2023-08-12 |
Not clear |
| Huiqing Li, Sheila Cherry, Donna Klinedinst, Valerie DeLeon, Jennifer Redig, Benjamin Reshey, Michael T Chin, Stephanie L Sherman, Cheryl L Maslen, Roger H Reeve. Genetic modifiers predisposing to congenital heart disease in the sensitized Down syndrome population. Circulation. Cardiovascular genetics. vol 5. issue 3. 2012-10-22. PMID:22523272. |
about half of people with down syndrome (ds) exhibit some form of congenital heart disease (chd); however, trisomy for human chromosome 21 (hsa21) alone is insufficient to cause chd, as half of all people with ds have a normal heart, suggesting that genetic modifiers interact with dosage-sensitive gene(s) on hsa21 to result in chd. |
2012-10-22 |
2023-08-12 |
human |
| F P Pellegrini, M Marinoni, V Frangione, A Tedeschi, V Gandini, F Ciglia, L Mortara, R S Accolla, L Nespol. Down syndrome, autoimmunity and T regulatory cells. Clinical and experimental immunology. vol 169. issue 3. 2012-10-16. PMID:22861363. |
autoimmune diseases are more represented in down syndrome (ds) individuals compared to chromosomally normal people. |
2012-10-16 |
2023-08-12 |
human |
| Emília de Faria Oliveira, Suelly Cecilia Olivan Limong. Quality of life of parents/caregivers of children and adolescents with Down syndrome. Jornal da Sociedade Brasileira de Fonoaudiologia. vol 23. issue 4. 2012-10-15. PMID:22231052. |
to assess the quality of life (lq) of parents/caregivers of children and adolescents with down syndrome (ds), as well as the influence of socio-demographic aspects on the results obtained. |
2012-10-15 |
2023-08-12 |
Not clear |
| Anindita Roy, Irene Roberts, Paresh Vya. Biology and management of transient abnormal myelopoiesis (TAM) in children with Down syndrome. Seminars in fetal & neonatal medicine. vol 17. issue 4. 2012-10-12. PMID:22421527. |
children with down syndrome (ds) have an increased risk of acute myeloid leukaemia (ml-ds), particularly megakaryoblastic leukaemia, which is clonally -related to the neonatal myeloproliferative syndrome, transient abnormal myelopoiesis (tam) unique to infants with ds. |
2012-10-12 |
2023-08-12 |
Not clear |
| José Morales-Roselló, Rafael Lázaro-Santande. Prenatal diagnosis of down syndrome associated with right aortic arch and dilated septum cavi pellucidi. Case reports in obstetrics and gynecology. vol 2012. 2012-10-12. PMID:23056970. |
a novel association between down syndrome and dilated cavum septi pellucidi is reported and the relationship between ds and vascular rings is discussed. |
2012-10-12 |
2023-08-12 |
Not clear |
| Edmund C Jenkins, Lingling Ye, Milen Velinov, Sharon J Krinsky-McHale, Warren B Zigman, Nicole Schupf, Wayne P Silverma. Mild cognitive impairment identified in older individuals with Down syndrome by reduced telomere signal numbers and shorter telomeres measured in microns. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22592955. |
previously, we established that short-term t lymphocyte cultures from people with down syndrome (ds) and dementia (alzheimer's disease) had shorter telomeres than did those from age- and sex-matched people with ds only, quantified as significantly reduced numbers of signals of peptide nucleic acid (pna) telomere probes in whole metaphases [jenkins et al. |
2012-10-11 |
2023-08-12 |
Not clear |
| Chiara Rigoldi, Manuela Galli, Veronica Cimolin, Filippo Camerota, Claudia Celletti, Nunzio Tenore, Giorgio Albertin. Gait strategy in patients with Ehlers-Danlos syndrome hypermobility type and Down syndrome. Research in developmental disabilities. vol 33. issue 5. 2012-10-09. PMID:22522202. |
the same condition is present in people suffering from down syndrome (ds) even if their clumsy movements are due to cerebral and cognitive impairments. |
2012-10-09 |
2023-08-12 |
human |
| Narayan Ramakrishna, Harry C Meeker, Satyam Patel, Ted W Brown, Abdeslem El Idriss. Regulation of α-synuclein expression in Down syndrome. Journal of neuroscience research. vol 90. issue 8. 2012-10-05. PMID:22473712. |
the triplication of genes located on chromosome 21 is known to cause a wide spectrum of pathology seen in down syndrome (ds), including leukemia, seizures, stroke, and mental retardation. |
2012-10-05 |
2023-08-12 |
mouse |
| V S Mercer, C L Lewi. Hip Abductor and Knee Extensor Muscle Strength of Children with and without Down Syndrome. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 13. issue 1. 2012-10-02. PMID:17053646. |
the purposes of this study were to 1) determine test-retest reliability of hand-held dynamometer measurements of right hip abductor and knee extensor muscle strength in children with down syndrome (ds), 2) identify differences in isometric muscle strength between children with ds and peers who are developing typically, and 3) determine the relationship between various anthropometric and demographic variables and isometric muscle strength. |
2012-10-02 |
2023-08-12 |
Not clear |