| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arpita Dey, Krishnendu Bhowmik, Arpita Chatterjee, Pit Baran Chakrabarty, Swagata Sinha, Kanchan Mukhopadhya. Down Syndrome Related Muscle Hypotonia: Association with COL6A3 Functional SNP rs2270669. Frontiers in genetics. vol 4. 2013-04-30. PMID:23626599. |
down syndrome (ds), the principal cause for intellectual disability, is also associated with hormonal, immunological, and gastrointestinal abnormalities. |
2013-04-30 |
2023-08-12 |
human |
| M Martinez de Lagran, R Benavides-Piccione, I Ballesteros-Yañez, M Calvo, M Morales, C Fillat, J Defelipe, G J A Ramakers, M Diersse. Dyrk1A influences neuronal morphogenesis through regulation of cytoskeletal dynamics in mammalian cortical neurons. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 12. 2013-04-29. PMID:22215728. |
down syndrome (ds) is the most frequent genetic cause of mental retardation. |
2013-04-29 |
2023-08-12 |
Not clear |
| Sara J McCullough, Julie-Anne Little, Kathryn J Saunder. Higher order aberrations in children with Down syndrome. Investigative ophthalmology & visual science. vol 54. issue 2. 2013-04-24. PMID:23361511. |
down syndrome (ds) is associated with ocular abnormalities and reduced visual function. |
2013-04-24 |
2023-08-12 |
Not clear |
| Aarti Ruparelia, Matthew L Pearn, William C Moble. Cognitive and pharmacological insights from the Ts65Dn mouse model of Down syndrome. Current opinion in neurobiology. vol 22. issue 5. 2013-04-22. PMID:22658745. |
down syndrome (ds) is a multi-faceted condition resulting in the most common genetic form of intellectual disability. |
2013-04-22 |
2023-08-12 |
mouse |
| Carmen Martínez-Cué, Paula Martínez, Noemí Rueda, Rebeca Vidal, Susana García, Verónica Vidal, Andrea Corrales, Juan A Montero, Ángel Pazos, Jesús Flórez, Rodolfo Gasser, Andrew W Thomas, Michael Honer, Frédéric Knoflach, Jose Luis Trejo, Joseph G Wettstein, Maria-Clemencia Hernánde. Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 9. 2013-04-22. PMID:23447605. |
down syndrome (ds) is associated with neurological complications, including cognitive deficits that lead to impairment in intellectual functioning. |
2013-04-22 |
2023-08-12 |
mouse |
| Karl Sperling, Heidemarie Neitzel, Hagen Scher. Evidence for an increase in trisomy 21 (Down syndrome) in Europe after the Chernobyl reactor accident. Genetic epidemiology. vol 36. issue 1. 2013-04-19. PMID:22162022. |
the objective of this study is to investigate the prevalence of down syndrome (ds) associated with chernobyl fallout. |
2013-04-19 |
2023-08-12 |
Not clear |
| Wei-Hong Siew, Kai-Leng Tan, Maryam Abbaspour Babaei, Pike-See Cheah, King-Hwa Lin. MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome. Frontiers in cellular neuroscience. vol 7. 2013-04-19. PMID:23596395. |
in this review, we aim to consolidate and assimilate the latest development and findings on a class of small non-coding rnas known as micrornas (mirnas) involvement in id development and progression with special focus on down syndrome (ds) and x-linked id (xlid) [including fragile x syndrome (fxs)]. |
2013-04-19 |
2023-08-12 |
Not clear |
| Helma B M van Gameren-Oosterom, S E Buitendijk, C M Bilardo, Karin M van der Pal-de Bruin, J P Van Wouwe, A D Mohango. Unchanged prevalence of Down syndrome in the Netherlands: results from an 11-year nationwide birth cohort. Prenatal diagnosis. vol 32. issue 11. 2013-04-18. PMID:22865545. |
this study aims to evaluate trends in prevalence of down syndrome (ds) births in the netherlands over an 11-year period and how they have been affected by maternal age and introduction of prenatal screening. |
2013-04-18 |
2023-08-12 |
Not clear |
| Chan-Kyung J Cho, Andrei P Drabovich, George S Karagiannis, Eduardo Martínez-Morillo, Shawn Dason, Apostolos Dimitromanolakis, Eleftherios P Diamandi. Quantitative proteomic analysis of amniocytes reveals potentially dysregulated molecular networks in Down syndrome. Clinical proteomics. vol 10. issue 1. 2013-04-17. PMID:23394617. |
down syndrome (ds), caused by an extra copy of chromosome 21, affects 1 in 750 live births and is characterized by cognitive impairment and a constellation of congenital defects. |
2013-04-17 |
2023-08-12 |
Not clear |
| Michel E Weijerman, Chantal J M Broers, Roos N van der Pla. [New insights into the support of children with Down syndrome]. Nederlands tijdschrift voor geneeskunde. vol 157. issue 6. 2013-04-15. PMID:23388138. |
the prevalence of down syndrome (ds) in the netherlands is 14/10,000 live births; this is almost 1.5 times higher than during the 1980s and 90 s. in the netherlands the uptake of prenatal screening is lower than in the rest of europe and the percentage of pregnant women > 36 years has increased. |
2013-04-15 |
2023-08-12 |
Not clear |
| Arpita Chatterjee, Samikshan Dutta, Sanjit Mukherjee, Nupur Mukherjee, Avirup Dutta, Ashis Mukherjee, Swagata Sinha, Chinmay Kumar Panda, Keya Chaudhuri, Ananda L Roy, Kanchan Mukhopadhya. Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies. BMC medical genetics. vol 14. 2013-04-12. PMID:23343470. |
subjects with down syndrome (ds) have a higher incidence of acute lymphoblastic leukemia (all) while solid tumors, like breast cancer (bc) and oral cancer (oc), show rare incidences. |
2013-04-12 |
2023-08-12 |
human |
| Debarati Ghosh, Sailesh Gochhait, Disha Banerjee, Anindita Chatterjee, Swagata Sinha, Krishnadas Nandagopa. SNaPshot Assay in Quantitative Detection of Allelic Nondisjunction in Down Syndrome. Genetic testing and molecular biomarkers. vol 16. issue 10. 2013-04-08. PMID:22931243. |
we wished to identify markers associated with allelic nondisjunction in nuclear families with down syndrome (ds) offspring. |
2013-04-08 |
2023-08-12 |
Not clear |
| b' Noem\\xc3\\xad Rueda, Jes\\xc3\\xbas Fl\\xc3\\xb3rez, Carmen Mart\\xc3\\xadnez-Cu\\xc3\\xa. Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities. Neural plasticity. vol 2012. 2013-04-03. PMID:22685678.' |
down syndrome (ds) is the most common genetic cause of mental disability. |
2013-04-03 |
2023-08-12 |
mouse |
| Hui-Yi Wang, I-Man Long, Mei-Fang Li. Relationships between task-oriented postural control and motor ability in children and adolescents with Down syndrome. Research in developmental disabilities. vol 33. issue 6. 2013-03-29. PMID:22699252. |
individuals with down syndrome (ds) have been characterized by greater postural sway in quiet stance and insufficient motor ability. |
2013-03-29 |
2023-08-12 |
human |
| Massimiliano Pau, Manuela Galli, Marcello Crivellini, Giorgio Albertin. Foot-ground interaction during upright standing in children with Down syndrome. Research in developmental disabilities. vol 33. issue 6. 2013-03-29. PMID:22717405. |
this study aimed to quantitatively characterize the main foot-ground contact parameters during static upright standing and to assess foot evolution with increasing age in young individuals affected by down syndrome (ds). |
2013-03-29 |
2023-08-12 |
human |
| Huai-En Lu, Yao-Chen Yang, Sheng-Mei Chen, Hong-Lin Su, Pai-Cheng Huang, Ming-Song Tsai, Tzu-Hao Wang, Ching-Ping Tseng, Shiaw-Min Hwan. Modeling neurogenesis impairment in Down syndrome with induced pluripotent stem cells from Trisomy 21 amniotic fluid cells. Experimental cell research. vol 319. issue 4. 2013-03-28. PMID:23041301. |
down syndrome (ds), or trisomy 21 (t21) syndrome, one of the most common chromosomal abnormalities, is caused by an extra duplication of chromosome 21. |
2013-03-28 |
2023-08-12 |
human |
| Elizabeth Kida, Ausma Rabe, Marius Walus, Giorgio Albertini, Adam A Golabe. Long-term running alleviates some behavioral and molecular abnormalities in Down syndrome mouse model Ts65Dn. Experimental neurology. vol 240. 2013-03-25. PMID:23201095. |
in the present study, we investigated whether voluntary daily running, sustained over several months, might improve cognition and motor function and modify the brain levels of selected proteins (sod1, dyrk1a, map2, app and synaptophysin) in ts65dn mice, a mouse model for down syndrome (ds). |
2013-03-25 |
2023-08-12 |
mouse |
| Renu Sinha, Chitra Rajeswari Thangaswamy, Thilaka Muthiah, Parul Chandra, Rajeshwari Subramania. Prolonged postoperative desaturation in a child with Down syndrome and atrial septal defect. Indian journal of anaesthesia. vol 55. issue 6. 2013-03-17. PMID:22223907. |
we report prolonged desaturation in a child with down syndrome (ds) and atrial septal defect due to undiagnosed interstitial lung disease. |
2013-03-17 |
2023-08-12 |
Not clear |
| Christine Ackerman, Adam E Locke, Eleanor Feingold, Benjamin Reshey, Karina Espana, Janita Thusberg, Sean Mooney, Lora J H Bean, Kenneth J Dooley, Clifford L Cua, Roger H Reeves, Stephanie L Sherman, Cheryl L Masle. An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects. American journal of human genetics. vol 91. issue 4. 2013-03-17. PMID:23040494. |
atrioventricular septal defects (avsd) are the most commonly occurring heart defects in down syndrome (ds), and ∼65% of all avsd is associated with ds. |
2013-03-17 |
2023-08-12 |
Not clear |
| R Boada, C Hutaff-Lee, A Schrader, D Weitzenkamp, T A Benke, E J Goldson, A C S Cost. Antagonism of NMDA receptors as a potential treatment for Down syndrome: a pilot randomized controlled trial. Translational psychiatry. vol 2. 2013-03-14. PMID:22806212. |
down syndrome (ds) is the most common genetic cause of intellectual disability. |
2013-03-14 |
2023-08-12 |
mouse |