| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie-Anne Little, Sara McCullough, Julie McClelland, A Jonathan Jackson, Kathryn J Saunder. Low-contrast acuity measurement: does it add value in the visual assessment of down syndrome and cerebral palsy populations? Investigative ophthalmology & visual science. vol 54. issue 1. 2013-03-12. PMID:23233262. |
children with down syndrome (ds) and cerebral palsy (cp) often have reduced visual acuity (va). |
2013-03-12 |
2023-08-12 |
Not clear |
| Andrea Contestabile, Barbara Greco, Diego Ghezzi, Valter Tucci, Fabio Benfenati, Laura Gasparin. Lithium rescues synaptic plasticity and memory in Down syndrome mice. The Journal of clinical investigation. vol 123. issue 1. 2013-03-11. PMID:23202733. |
down syndrome (ds) patients exhibit abnormalities of hippocampal-dependent explicit memory, a feature that is replicated in relevant mouse models of the disease. |
2013-03-11 |
2023-08-12 |
mouse |
| Denise M O'Driscoll, Rosemary S C Horne, Margot J Davey, Sarah A Hope, Vicki Anderson, John Trinder, Adrian M Walker, Gillian M Nixo. Cardiac and sympathetic activation are reduced in children with Down syndrome and sleep disordered breathing. Sleep. vol 35. issue 9. 2013-03-06. PMID:22942505. |
sleep disordered breathing (sdb) occurs at an increased incidence in children with down syndrome (ds) compared to the general pediatric population. |
2013-03-06 |
2023-08-12 |
Not clear |
| Javiera A Catalán, Fernando A Rodríguez, María J Yubero, Francis Palisson, María J Gana, Susanne M Krämer, Gabriela M Repett. De Novo COL7A1 mutation in a patient with trisomy 21: coexistence of dystrophic epidermolysis bullosa and Down syndrome. International journal of dermatology. vol 51. issue 9. 2013-03-04. PMID:22909362. |
down syndrome (ds) is the most common autosomal chromosomal disorder. |
2013-03-04 |
2023-08-12 |
Not clear |
| James E Kucik, Mikyong Shin, Csaba Siffel, Lisa Marengo, Adolfo Corre. Trends in survival among children with Down syndrome in 10 regions of the United States. Pediatrics. vol 131. issue 1. 2013-02-22. PMID:23248222. |
this study examined changes in survival among children with down syndrome (ds) by race/ethnicity in 10 regions of the united states. |
2013-02-22 |
2023-08-12 |
Not clear |
| Patrick M Cowley, Stefan Keslacy, Frank A Middleton, Lara R DeRuisseau, Bo Fernhall, Jill A Kanaley, Keith C DeRuissea. Functional and biochemical characterization of soleus muscle in Down syndrome mice: insight into the muscle dysfunction seen in the human condition. American journal of physiology. Regulatory, integrative and comparative physiology. vol 303. issue 12. 2013-02-21. PMID:23115123. |
persons with down syndrome (ds) exhibit low muscle strength that significantly impairs their physical functioning. |
2013-02-21 |
2023-08-12 |
mouse |
| Adviye A Tolun, Peter M Scarbrough, Haoyue Zhang, Jane-Ann McKillop, Frances Wang, Priya S Kishnani, David S Millington, Sarah P Young, Dora Il'yasov. Systemic oxidative stress, as measured by urinary allantoin and F(2)-isoprostanes, is not increased in Down syndrome. Annals of epidemiology. vol 22. issue 12. 2013-02-20. PMID:23063134. |
oxidative stress has been implicated in down syndrome (ds) pathology. |
2013-02-20 |
2023-08-12 |
Not clear |
| Homa Attar, Karen Bedard, Eugenia Migliavacca, Maryline Gagnebin, Yann Dupré, Patrick Descombes, Christelle Borel, Samuel Deutsch, Holger Prokisch, Thomas Meitinger, Divya Mehta, Erich Wichmann, Jean Maurice Delabar, Emmanouil T Dermitzakis, Karl-Heinz Krause, Stylianos E Antonaraki. Extensive natural variation for cellular hydrogen peroxide release is genetically controlled. PloS one. vol 7. issue 8. 2013-02-19. PMID:22952707. |
finally, a highly significant decrease in h(2)o(2) release was observed in down syndrome (ds) individuals (p<2.88×10-12). |
2013-02-19 |
2023-08-12 |
human |
| Ohad Baruchin, Ron Maymon, Arie Herman, Yosef Tuvbin, Oshri Barel, Ariel Zimerman, Zvi Vakni. [The findings and sequence of events leading to termination of pregnancy due to Down's syndrome--before and after the verge of viability: 10 years experience at a single medical center]. Harefuah. vol 151. issue 11. 2013-02-15. PMID:23367726. |
to assess the differences in the sequence of events, leading to termination of pregnancy (top) due to diagnosis of down syndrome (ds). |
2013-02-15 |
2023-08-12 |
Not clear |
| Rima Obeid, Kathrin Hartmuth, Wolfgang Herrmann, Ludwig Gortner, Tilman R Rohrer, Jürgen Geisel, Michael C Reed, H Frederik Nijhou. Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model. Molecular nutrition & food research. vol 56. issue 10. 2013-02-11. PMID:22930479. |
the study tests the metabolites of the methylation cycle in individuals with down syndrome (ds) and applies a mathematical model in order to change this cycle by nutritional factors. |
2013-02-11 |
2023-08-12 |
Not clear |
| Julia Looper, Danielle Benjamin, Mindy Nolan, Laura Schum. What to measure when determining orthotic needs in children with Down syndrome: a pilot study. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 24. issue 4. 2013-02-06. PMID:22965200. |
to compare the effects of off-the-shelf foot orthoses and supramalleolar orthoses on the gait of children with down syndrome (ds), and establish criteria for determining orthoses prescription for a child with ds. |
2013-02-06 |
2023-08-12 |
Not clear |
| Karol Dowjat, Tatyana Adayev, Wojciech Kaczmarski, Jerzy Wegiel, Yu-Wen Hwan. Gene dosage-dependent association of DYRK1A with the cytoskeleton in the brain and lymphocytes of down syndrome patients. Journal of neuropathology and experimental neurology. vol 71. issue 12. 2013-02-04. PMID:23147510. |
the triplication of the dyrk1a gene encoding proline-directed serine/threonine kinase and located in the critical region of down syndrome (ds) has been implicated in cognitive deficits and intellectual disability of individuals with ds. |
2013-02-04 |
2023-08-12 |
human |
| Helma B M van Gameren-Oosterom, Paula van Dommelen, Yvonne Schönbeck, Anne Marie Oudesluys-Murphy, Jacobus P van Wouwe, Simone E Buitendij. Prevalence of overweight in Dutch children with Down syndrome. Pediatrics. vol 130. issue 6. 2013-02-04. PMID:23147968. |
this study aims to establish growth references for weight and to assess the prevalence rates of overweight and obesity in a nationwide sample of dutch children with down syndrome (ds), taking into account the influence of comorbidity. |
2013-02-04 |
2023-08-12 |
Not clear |
| Ariel Tenenbaum, Eyal Lebel, Sarah Malkiel, Yael Kastiel, Abdulsalam Abulibdeh, David Haim Zange. Euthyroid submedian free T4 and subclinical hypothyroidism may have a detrimental clinical effect in Down syndrome. Hormone research in paediatrics. vol 78. issue 2. 2013-02-01. PMID:22922417. |
aberrant thyroid function is highly prevalent in down syndrome (ds). |
2013-02-01 |
2023-08-12 |
Not clear |
| Claire Spellman, Md Mahiuddin Ahmed, Daphne Dubach, Katheleen J Gardine. Expression of trisomic proteins in Down syndrome model systems. Gene. vol 512. issue 2. 2013-02-01. PMID:23103828. |
down syndrome (ds) is the most common genetic aberration leading to intellectual disability. |
2013-02-01 |
2023-08-12 |
mouse |
| Laura Seewald, Jeffrey W Taub, Kelly W Maloney, Edward R B McCab. Acute leukemias in children with Down syndrome. Molecular genetics and metabolism. vol 107. issue 1-2. 2013-01-29. PMID:22867885. |
children with down syndrome (ds) often present with hematopoietic abnormalities, and are at increased risk of developing leukemia. |
2013-01-29 |
2023-08-12 |
Not clear |
| Z Elmagrpy, A Rayani, A Shah, E Habas, E H Aburaw. Down syndrome and congenital heart disease: why the regional difference as observed in the Libyan experience? Cardiovascular journal of Africa. vol 22. issue 6. 2013-01-25. PMID:22159317. |
children with down syndrome (ds) have about a 40 to 50% incidence of congenital heart disease (chd). |
2013-01-25 |
2023-08-12 |
Not clear |
| Naznin Virji-Babul, Kimberley Watt, Farouk Nathoo, Peter Johnso. Recognition of facial expressions of emotion in adults with Down syndrome. Physical & occupational therapy in pediatrics. vol 32. issue 3. 2013-01-17. PMID:22304421. |
research on facial expressions in individuals with down syndrome (ds) has been conducted using photographs. |
2013-01-17 |
2023-08-12 |
Not clear |
| Ishwar C Verma, Meena Lall, Ratna Dua Pur. Down syndrome in India--diagnosis, screening, and prenatal diagnosis. Clinics in laboratory medicine. vol 32. issue 2. 2013-01-17. PMID:22727002. |
down syndrome (ds) is the most common genetic cause of mental retardation. |
2013-01-17 |
2023-08-12 |
mouse |
| Jack-Christophe Cossec, Jérémie Lavaur, Diego E Berman, Isabelle Rivals, Alexander Hoischen, Samantha Stora, Clémentine Ripoll, Clotilde Mircher, Yann Grattau, Jean-Christophe Olivomarin, Fabrice de Chaumont, Magalie Lecourtois, Stylianos E Antonarakis, Joris A Veltman, Jean M Delabar, Charles Duyckaerts, Gilbert Di Paolo, Marie-Claude Potie. Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes. Human molecular genetics. vol 21. issue 14. 2013-01-14. PMID:22511594. |
enlarged early endosomes have been observed in neurons and fibroblasts in down syndrome (ds). |
2013-01-14 |
2023-08-12 |
mouse |