| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gert de Graaf, Frank Buckley, Brian G Skotk. Estimates of the live births, natural losses, and elective terminations with Down syndrome in the United States. American journal of medical genetics. Part A. vol 167A. issue 4. 2015-12-17. PMID:25822844. |
the present and future live birth prevalence of down syndrome (ds) is of practical importance for planning services and prioritizing research to support people living with the condition. |
2015-12-17 |
2023-08-13 |
Not clear |
| Daniela Necchi, Antonella Pinto, Micol Tillhon, Ilaria Dutto, Melania Maria Serafini, Cristina Lanni, Stefano Govoni, Marco Racchi, Ennio Prosper. Defective DNA repair and increased chromatin binding of DNA repair factors in Down syndrome fibroblasts. Mutation research. vol 780. 2015-12-17. PMID:26258283. |
down syndrome (ds) is characterized by genetic instability, neurodegeneration, and premature aging. |
2015-12-17 |
2023-08-13 |
Not clear |
| Bernhard Steiner, Rahim Masood, Kaspar Rufibach, Dunja Niedrist, Oliver Kundert, Mariluce Riegel, Albert Schinze. An unexpected finding: younger fathers have a higher risk for offspring with chromosomal aneuploidies. European journal of human genetics : EJHG. vol 23. issue 4. 2015-12-15. PMID:25005732. |
the couples with younger fathers face almost twofold odds for a child with down syndrome (ds). |
2015-12-15 |
2023-08-13 |
Not clear |
| Long H Do, William C Mobley, Nishant Singha. Questioned validity of Gene Expression Dysregulated Domains in Down's Syndrome. F1000Research. vol 4. 2015-12-15. PMID:26664707. |
fetuses derived from the same egg) discordant for trisomy 21 (down syndrome; ds), letourneau et al., ( )reported the presence of a defined pattern of dysregulation within specific genomic domains they referred to as gene expression dysregulated domains (gedds). |
2015-12-15 |
2023-08-13 |
mouse |
| Fabio Coppedè, Paolo Bosco, Valentina Lorenzoni, Maria Denaro, Guido Anello, Ivana Antonucci, Concetta Barone, Liborio Stuppia, Corrado Romano, Lucia Miglior. The MTRR 66A>G polymorphism and maternal risk of birth of a child with Down syndrome in Caucasian women: a case-control study and a meta-analysis. Molecular biology reports. vol 41. issue 9. 2015-12-14. PMID:24965145. |
we performed a large case-control study and a meta-analysis of the literature to address the role of the methionine synthase reductase (mtrr) c.66a>g polymorphism as a maternal risk factor for the birth of a child with down syndrome (ds) among caucasian women. |
2015-12-14 |
2023-08-13 |
Not clear |
| Dean Nizetic, Christopher L Chen, Wanjin Hong, Edward H Ko. Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP. Frontiers in behavioral neuroscience. vol 9. 2015-12-09. PMID:26648852. |
people with down syndrome (ds) virtually all develop intellectual disability (id) of varying degree of severity, and also have a high risk of early alzheimer's disease (ad). |
2015-12-09 |
2023-08-13 |
Not clear |
| Xavier Liogier d'Ardhuy, Jamie O Edgin, Charles Bouis, Susana de Sola, Celia Goeldner, Priya Kishnani, Jana Nöldeke, Sydney Rice, Silvia Sacco, Lisa Squassante, Gail Spiridigliozzi, Jeannie Visootsak, James Heller, Omar Khwaj. Assessment of Cognitive Scales to Examine Memory, Executive Function and Language in Individuals with Down Syndrome: Implications of a 6-month Observational Study. Frontiers in behavioral neuroscience. vol 9. 2015-12-04. PMID:26635554. |
down syndrome (ds) is the most commonly identifiable genetic form of intellectual disability. |
2015-12-04 |
2023-08-13 |
Not clear |
| Laura Del Hoyo, Laura Xicota, Gonzalo Sánchez-Benavides, Aida Cuenca-Royo, Susana de Sola, Klaus Langohr, Ana B Fagundo, Magí Farré, Mara Dierssen, Rafael de la Torr. Semantic Verbal Fluency Pattern, Dementia Rating Scores and Adaptive Behavior Correlate With Plasma Aβ42 Concentrations in Down Syndrome Young Adults. Frontiers in behavioral neuroscience. vol 9. 2015-12-04. PMID:26635555. |
down syndrome (ds) is an intellectual disability (id) disorder in which language and specifically, verbal fluency are strongly impaired domains; nearly all adults show neuropathology of alzheimer's disease (ad), including amyloid deposition by their fifth decade of life. |
2015-12-04 |
2023-08-13 |
Not clear |
| Lise Cronberg Salem, Anne Sabers, Troels W Kjaer, Christian Musaeus, Martin N Nielsen, Anne-Grete Nielsen, Gunhild Waldema. Quantitative Electroencephalography as a Diagnostic Tool for Alzheimer's Dementia in Adults with Down Syndrome. Dementia and geriatric cognitive disorders extra. vol 5. issue 3. 2015-12-02. PMID:26628899. |
the aim of this study was to examine the value of qeeg in the diagnostic evaluation of dementia in patients with down syndrome (ds). |
2015-12-02 |
2023-08-13 |
Not clear |
| Nandini Singh, Tara Dutka, Benjamin M Devenney, Kazuhiko Kawasaki, Roger H Reeves, Joan T Richtsmeie. Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology. Disease models & mechanisms. vol 8. issue 3. 2015-12-01. PMID:25540129. |
in particular, a reduced mitogenic response of cerebellar granule cell precursors to shh signaling in a mouse model for down syndrome (ds), ts65dn, is substantially responsible for reduced cerebellar size. |
2015-12-01 |
2023-08-13 |
mouse |
| Damien Marechal, Patricia Lopes Pereira, Arnaud Duchon, Yann Heraul. Dosage of the Abcg1-U2af1 region modifies locomotor and cognitive deficits observed in the Tc1 mouse model of Down syndrome. PloS one. vol 10. issue 2. 2015-12-01. PMID:25706610. |
down syndrome (ds) results from one extra copy of human chromosome 21 and leads to several alterations including intellectual disabilities and locomotor defects. |
2015-12-01 |
2023-08-13 |
mouse |
| F I Vos, M Bakker, E A P de Jong-Pleij, L S M Ribbert, E Tromp, C M Bilard. Is 3D technique superior to 2D in Down syndrome screening? Evaluation of six second and third trimester fetal profile markers. Prenatal diagnosis. vol 35. issue 3. 2015-11-30. PMID:25346246. |
the objective of this article is to investigate whether in the clinical setting of second trimester ultrasound (us) investigations, 3d multiplanar correction prior to the measurement of down syndrome (ds) facial markers (nasal bone length, prenasal thickness, fetal profile line, maxilla-nasion-mandible angle, prenasal thickness to nasal bone length ratio, and prefrontal space ratio) is superior to subjective judgment of a correct midsagittal plane by 2d technique. |
2015-11-30 |
2023-08-13 |
Not clear |
| Arpita Dey, Arpita Chatterjee, Atanu Maiti, Nupur Mukherjee, Swagata Sinha, Chinmay K Panda, Kanchan Mukhopadhya. Biased paternal transmission of TRH variant to female Down syndrome probands: possible correlation with low breast cancer frequency. The International journal of biological markers. vol 30. issue 1. 2015-11-23. PMID:25362934. |
thyroid malfunction is more common in individuals with down syndrome (ds) than in the general population. |
2015-11-23 |
2023-08-13 |
human |
| Manuela Galli, Veronica Cimolin, Chiara Rigoldi, Claudia Condoluci, Giorgio Albertin. Effects of obesity on gait pattern in young individuals with Down syndrome. International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation. vol 38. issue 1. 2015-11-23. PMID:25419690. |
in individuals with down syndrome (ds), the prevalence of obesity is widespread; despite this, there are no experimental studies on the effect of obesity on gait strategy in ds individuals. |
2015-11-23 |
2023-08-13 |
human |
| J H Lim, D J Kim, D E Lee, J Y Han, J H Chung, H K Ahn, S W Lee, D H Lim, Y S Lee, S Y Park, H M Ry. Genome-wide microRNA expression profiling in placentas of fetuses with Down syndrome. Placenta. vol 36. issue 3. 2015-11-20. PMID:25595853. |
down syndrome (ds) is the most common aneuploidy, caused by an extra copy of all or part of chromosome 21 (chr21). |
2015-11-20 |
2023-08-13 |
human |
| Marie Moore Channell, Andrea S McDuffie, Lauren M Bullard, Leonard Abbedut. Narrative language competence in children and adolescents with Down syndrome. Frontiers in behavioral neuroscience. vol 9. 2015-11-20. PMID:26578913. |
this study was designed to examine the narrative language abilities of children and adolescents with down syndrome (ds) in comparison to same-age peers with fragile x syndrome (fxs) and younger typically developing (td) children matched by nonverbal cognitive ability levels. |
2015-11-20 |
2023-08-13 |
human |
| Tatiana Dias de Carvalho, Luiz Carlos de Abreu, Zan Mustacchi, Luiz Carlos Marques Vanderlei, Moacir Fernandes Godoy, Rodrigo Daminello Raimundo, Celso Ferreira Filho, Talita Dias da Silva, Laura Guilhoto, Viviane Perico, Vivian Ribeiro Finotti, Celso Ferreir. Cardiac autonomic modulation of children with Down syndrome. Pediatric cardiology. vol 36. issue 2. 2015-11-17. PMID:25164236. |
the aim of this study is to analyze the autonomic modulation in children with down syndrome (ds). |
2015-11-17 |
2023-08-13 |
human |
| Christina Yeager Pelatt. Enhancing oral and written language for adolescents and young adults with Down syndrome. Seminars in speech and language. vol 36. issue 1. 2015-11-17. PMID:25633144. |
oral and written language development for adolescents and young adults with down syndrome (ds) are particularly challenging. |
2015-11-17 |
2023-08-13 |
Not clear |
| Brett S Nickerson, Michael R Esco, Sara C Bicard, Angela R Russell, Henry N Williford, George Schaefe. Validity of the body adiposity index in adults with Down syndrome. Research in developmental disabilities. vol 38. 2015-11-16. PMID:25550123. |
the purpose of this investigation was to determine the agreement between the body adiposity index (bai) and dual energy x-ray absorptiometry (dxa) for measuring bf% in adults with down syndrome (ds). |
2015-11-16 |
2023-08-13 |
Not clear |
| Hao-Ling Chen, Chun-Fu Yeh, Tsu-Hsin How. Postural control during standing reach in children with Down syndrome. Research in developmental disabilities. vol 38. 2015-11-16. PMID:25590172. |
the purpose of the present study was to investigate the dynamic postural control of children with down syndrome (ds). |
2015-11-16 |
2023-08-13 |
Not clear |