| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesca Pulina, Barbara Carretti, Silvia Lanfranchi, Irene C Mammarell. Improving spatial-simultaneous working memory in Down syndrome: effect of a training program led by parents instead of an expert. Frontiers in psychology. vol 6. 2015-09-18. PMID:26379590. |
recent studies have suggested that the visuospatial component of working memory (wm) is selectively impaired in individuals with down syndrome (ds), the deficit relating specifically to the spatial-simultaneous component, which is involved when stimuli are presented simultaneously. |
2015-09-18 |
2023-08-13 |
human |
| Michael P Hunter, Angela Russo, John P O'Brya. Emerging roles for intersectin (ITSN) in regulating signaling and disease pathways. International journal of molecular sciences. vol 14. issue 4. 2015-09-16. PMID:23574942. |
itsn has also been implicated in diseases such as down syndrome (ds), alzheimer disease (ad), and other neurodegenerative disorders. |
2015-09-16 |
2023-08-12 |
human |
| Alida Goffinski, Maria A Stanley, Nicole Shepherd, Nichole Duvall, Sandra B Jenkinson, Charlene Davis, Marilyn J Bull, Randall J Rope. Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic. American journal of medical genetics. Part A. vol 167A. issue 2. 2015-09-16. PMID:25604659. |
children with down syndrome (ds) experience congenital and functional medical issues that predispose them to obstructive sleep apnea (osa). |
2015-09-16 |
2023-08-13 |
Not clear |
| Sarah E Latchney, Thomas C Jaramillo, Phillip D Rivera, Amelia J Eisch, Craig M Powel. Chronic P7C3 treatment restores hippocampal neurogenesis in the Ts65Dn mouse model of Down Syndrome [Corrected]. Neuroscience letters. vol 591. 2015-09-15. PMID:25668489. |
down syndrome (ds) is the most common genetic cause of intellectual disability and developmental delay. |
2015-09-15 |
2023-08-13 |
mouse |
| Tara Dutka, Dorothy Hallberg, Roger H Reeve. Chronic up-regulation of the SHH pathway normalizes some developmental effects of trisomy in Ts65Dn mice. Mechanisms of development. vol 135. 2015-09-11. PMID:25511459. |
down syndrome (ds) is a highly complex developmental genetic disorder caused by trisomy for human chromosome 21 (hsa21). |
2015-09-11 |
2023-08-13 |
mouse |
| Flávia Cristina de Carvalho Mrad, José de Bessa, Adrianne Maria Berno de Rezende Duarte, Augusto Alves Pinho Vieira, Frederico Cantarino Cordeiro Araujo, Maíra Lorenzo de Sá Camargo, Sandra Helena Cerrato Tibiriça, André Avarese de Figueiredo, José Murillo de Bastos Nett. Prevalence of lower urinary tract symptoms in individuals with Down syndrome. Journal of pediatric urology. vol 10. issue 5. 2015-09-09. PMID:24726199. |
down syndrome (ds), which is caused by the trisomy of chromosome 21, is the most frequent of all genetic syndromes. |
2015-09-09 |
2023-08-13 |
Not clear |
| Jana Schweitzer, Martin Zimmermann, Mareike Rasche, Christine von Neuhoff, Ursula Creutzig, Michael Dworzak, Dirk Reinhardt, Jan-Henning Klusman. Improved outcome of pediatric patients with acute megakaryoblastic leukemia in the AML-BFM 04 trial. Annals of hematology. vol 94. issue 8. 2015-09-09. PMID:25913479. |
here, we report the outcome of 97 pediatric patients with de novo amkl (excluding down syndrome [ds]) enrolled in the prospective multicenter studies aml-bfm 98 and aml-bfm 04 (1998-2014). |
2015-09-09 |
2023-08-13 |
Not clear |
| Antonela Ljubic, Vladimir Trajkovski, Milorad Tesic, Biljana Tojtovska, Branislav Stankovi. Ophthalmic manifestations in children and young adults with Down syndrome and congenital heart defects. Ophthalmic epidemiology. vol 22. issue 2. 2015-09-01. PMID:25777312. |
to investigate whether different types of ocular manifestations are associated with congenital heart disease (chd) in a large caucasian population of children and young adults with down syndrome (ds). |
2015-09-01 |
2023-08-13 |
Not clear |
| Adolfo Quiñones-Lombraña, Javier G Blanc. Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM). Biochimica et biophysica acta. vol 1852. issue 7. 2015-08-27. PMID:25869329. |
in contrast, downregulation of tfam by hsa-mir-155-5p did not decrease mtdna content in fibroblasts derived from a donor with down syndrome (ds, trisomy 21). |
2015-08-27 |
2023-08-13 |
human |
| Jamie O Edgi. Cognition in Down syndrome: a developmental cognitive neuroscience perspective. Wiley interdisciplinary reviews. Cognitive science. vol 4. issue 3. 2015-08-26. PMID:26304208. |
down syndrome (ds) is the most common genetic form of intellectual disability. |
2015-08-26 |
2023-08-13 |
Not clear |
| Sarah B Martin, Amy L S Dowling, Joann Lianekhammy, Ira T Lott, Eric Doran, M Paul Murphy, Tina L Beckett, Frederick A Schmitt, Elizabeth Hea. Synaptophysin and synaptojanin-1 in Down syndrome are differentially affected by Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 42. issue 3. 2015-08-25. PMID:24927707. |
adults with down syndrome (ds) develop alzheimer's disease (ad) neuropathology by 40 years of age. |
2015-08-25 |
2023-08-13 |
Not clear |
| Giovanna Cenini, Ada Fiorini, Rukhsana Sultana, Marzia Perluigi, Jian Cai, Jon B Klein, Elizabeth Head, D Allan Butterfiel. An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach. Free radical biology & medicine. vol 76. 2015-08-25. PMID:25151119. |
down syndrome (ds) is one of the most common causes of intellectual disability, owing to trisomy of all or part of chromosome 21. |
2015-08-25 |
2023-08-13 |
human |
| Xiao Feng, Weidong Yu, Rong Liang, Cheng Shi, Zhuran Zhao, Jingzhu Gu. Receptor-interacting protein 140 overexpression promotes neuro-2a neuronal differentiation by ERK1/2 signaling. Chinese medical journal. vol 128. issue 1. 2015-08-25. PMID:25563324. |
abnormal neuronal differentiation plays an important role in central nervous system (cns) development abnormalities such as down syndrome (ds), a disorder that results directly from overexpression of genes in trisomic cells. |
2015-08-25 |
2023-08-13 |
Not clear |
| Christian Fausch, Christof Röösl. The incudomalleolar articulation in Down syndrome (trisomy 21): a temporal bone study. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. vol 36. issue 2. 2015-08-21. PMID:24914797. |
one reason for conductive hearing loss (hl) in patients with down syndrome (ds) is structural anomalies in the incudomalleolar joint (imj) that impair sound transmission. |
2015-08-21 |
2023-08-13 |
Not clear |
| Alain D Dekker, Antonia M W Coppus, Yannick Vermeiren, Tony Aerts, Cornelia M van Duijn, Berry P Kremer, Pieter J W Naudé, Debby Van Dam, Peter P De Dey. Serum MHPG strongly predicts conversion to Alzheimer's disease in behaviorally characterized subjects with Down syndrome. Journal of Alzheimer's disease : JAD. vol 43. issue 3. 2015-08-21. PMID:25125467. |
down syndrome (ds) is the most prevalent genetic cause of intellectual disability. |
2015-08-21 |
2023-08-13 |
human |
| Melanie A J Engels, Jos W R Twisk, Marinus A Blankenstein, John M G van Vug. First-trimester screening for down syndrome with serum sampling at different gestational ages: the effect on screening performance. Fetal diagnosis and therapy. vol 36. issue 4. 2015-08-21. PMID:25170623. |
the objective of this study was to evaluate the performance of first-trimester down syndrome (ds) screening with serum sampling at different weeks of gestation. |
2015-08-21 |
2023-08-13 |
Not clear |
| Jessica Sosa-Stanley, KellyAnn Vandendool, Jonathan Kie. Redo Heller Myotomy for Achalasia in a Patient with Down Syndrome: a Case Report. The West Virginia medical journal. vol 111. issue 4. 2015-08-21. PMID:26242027. |
up to 77% of down syndrome (ds) patients have associated structural or functional gastrointestinal abnormalities. |
2015-08-21 |
2023-08-13 |
Not clear |
| Qiannan Guo, Hongdan Wang, Ke Yang, Bo Zhang, Tao Li, Shixiu Lia. [Association of MTHFR and MTRR genes polymorphisms with non-disjunctions of chromosomes 18 and 21]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 32. issue 3. 2015-08-14. PMID:26037359. |
to explore the effect of mthfr and mtrr genes polymorphisms on chromosomes 18 and 21 non-disjunction through investigation of henan han chinese young females with a gestational history of trisomy 21 (down syndrome, ds) or trisomy 18 (edwards syndrome, es). |
2015-08-14 |
2023-08-13 |
Not clear |
| Paul J Yoder, Tiffany Woynaroski, Marc E Fey, Steven F Warren, Elizabeth Gardne. Why Dose Frequency Affects Spoken Vocabulary in Preschoolers With Down Syndrome. American journal on intellectual and developmental disabilities. vol 120. issue 4. 2015-08-13. PMID:26161468. |
in an earlier randomized clinical trial, daily communication and language therapy resulted in more favorable spoken vocabulary outcomes than weekly therapy sessions in a subgroup of initially nonverbal preschoolers with intellectual disabilities that included only children with down syndrome (ds). |
2015-08-13 |
2023-08-13 |
human |
| b' Aleksandra Gruszecka, Przemys\\xc5\\x82aw Kopczy\\xc5\\x84ski, Dorota Cudzi\\xc5\\x82o, Natalia Lipi\\xc5\\x84ska, Aleksandra Romaniuk, Wojciech Barczak, Natalia Rozwadowska, Ewa Toto\\xc5\\x84, B\\xc5\\x82a\\xc5\\xbcej Rubi\\xc5\\x9. Telomere shortening in Down syndrome patients--when does it start? DNA and cell biology. vol 34. issue 6. 2015-08-10. PMID:25786194.' |
down syndrome (ds) is one of the most common aneuploidy. |
2015-08-10 |
2023-08-13 |
human |