| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eirini Sanoudaki, Spyridoula Varlokost. Pronoun comprehension in individuals with Down syndrome: the role of age. International journal of language & communication disorders. vol 50. issue 2. 2016-01-07. PMID:25180983. |
a number of studies have suggested that language in individuals with down syndrome (ds) may not be simply delayed compared with language in typically developing (td) children, but deviant. |
2016-01-07 |
2023-08-13 |
Not clear |
| Susheel Joginder Singh, Teresa Iacono, Kylie M Gra. Interactions of pre-symbolic children with developmental disabilities with their mothers and siblings. International journal of language & communication disorders. vol 50. issue 2. 2016-01-07. PMID:25585674. |
depending on the severity of their disabilities, children with down syndrome (ds) and with cerebral palsy (cp) may remain pre-symbolic for prolonged periods of time. |
2016-01-07 |
2023-08-13 |
Not clear |
| Lynette V Roberts, Jenny L Richmon. Preschoolers with Down syndrome do not yet show the learning and memory impairments seen in adults with Down syndrome. Developmental science. vol 18. issue 3. 2016-01-06. PMID:25283764. |
individuals with down syndrome (ds) exhibit a behavioral phenotype of specific strengths and weaknesses, in addition to a generalized cognitive delay. |
2016-01-06 |
2023-08-13 |
Not clear |
| Fiorenza Stagni, Andrea Giacomini, Sandra Guidi, Elisabetta Ciani, Elena Ragazzi, Mirco Filonzi, Rosaria De Iasio, Roberto Rimondini, Renata Bartesagh. Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice. Neurobiology of disease. vol 74. 2016-01-06. PMID:25497735. |
individuals with down syndrome (ds), a genetic condition caused by triplication of chromosome 21, are characterized by intellectual disability and are prone to develop alzheimer's disease (ad), due to triplication of the amyloid precursor protein (app) gene. |
2016-01-06 |
2023-08-13 |
mouse |
| Joshua D Blazek, Ahmed M Malik, Maeve Tischbein, Maria L Arbones, Clara S Moore, Randall J Rope. Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner. Mechanisms of development. vol 136. 2016-01-06. PMID:25556111. |
the relationship between gene dosage imbalance and phenotypes associated with trisomy 21, including the etiology of abnormal bone phenotypes linked to down syndrome (ds), is not well understood. |
2016-01-06 |
2023-08-13 |
mouse |
| R L Nosheny, P V Belichenko, B L Busse, A M Weissmiller, V Dang, D Das, A Fahimi, A Salehi, S J Smith, W C Moble. Increased cortical synaptic activation of TrkB and downstream signaling markers in a mouse model of Down Syndrome. Neurobiology of disease. vol 77. 2016-01-06. PMID:25753471. |
down syndrome (ds), trisomy 21, is characterized by synaptic abnormalities and cognitive deficits throughout the lifespan and with development of alzheimer's disease (ad) neuropathology and progressive cognitive decline in adults. |
2016-01-06 |
2023-08-13 |
mouse |
| T Leti, M Guinot, A Favre-Juvin, V-A Bricou. Difference of catecholamine responses to exercise in men with trisomy 21, with or without chronotropic incompetence. Physiology & behavior. vol 142. 2016-01-05. PMID:25660758. |
our purpose was to analyse if catecholamine responses to exercise would be different in down syndrome (ds) with or without chronotropic incompetence. |
2016-01-05 |
2023-08-13 |
Not clear |
| Renita C Polk, Peter Gergics, Jeffrey D Steimle, Huiqing Li, Ivan P Moskowitz, Sally A Camper, Roger H Reeve. The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model. BMC developmental biology. vol 15. 2016-01-05. PMID:26208718. |
nearly half of all individuals with down syndrome (ds) have some type of congenital heart defect (chd), suggesting that ds sensitizes to chd but does not cause it. |
2016-01-05 |
2023-08-13 |
mouse |
| Xingju Nie, Eric D Hamlett, Ann-Charlotte Granholm, Edward S Hui, Joseph A Helpern, Jens H Jensen, Heather A Boger, Heather R Collins, Maria F Falangol. Evidence of altered age-related brain cytoarchitecture in mouse models of down syndrome: a diffusional kurtosis imaging study. Magnetic resonance imaging. vol 33. issue 4. 2016-01-04. PMID:25527393. |
mouse models of down syndrome (ds) exhibit abnormal brain developmental and neurodegenerative changes similar to those seen in individuals with ds. |
2016-01-04 |
2023-08-13 |
mouse |
| Martine Hennequin, Marie-Noëlle Mazille, Pierre-Yves Cousson, Emmanuel Nicola. Increasing the number of inter-arch contacts improves mastication in adults with Down syndrome: a prospective controlled trial. Physiology & behavior. vol 145. 2016-01-04. PMID:25824190. |
feeding difficulties due to their condition have been widely described for babies, children and adults with down syndrome (ds). |
2016-01-04 |
2023-08-13 |
human |
| Prasad John Thottam, Sukgi Choi, Jeffrey P Simons, Dennis J Kitsk. Effect of Adenotonsillectomy on Central and Obstructive Sleep Apnea in Children with Down Syndrome. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. vol 153. issue 4. 2015-12-31. PMID:26044789. |
to determine and quantify changes in both central and obstructive sleep apnea in patients with down syndrome (ds) after adenotonsillectomy (at). |
2015-12-31 |
2023-08-13 |
Not clear |
| Larisa V Lysenko, Jeesun Kim, Cassandra Henry, Anna Tyrtyshnaia, Rebecca A Kohnz, Francisco Madamba, Gabriel M Simon, Natalia E Kleschevnikova, Daniel K Nomura, R Alan B Ezekowitz, Alexander M Kleschevniko. Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome. PloS one. vol 9. issue 12. 2015-12-29. PMID:25474204. |
down syndrome (ds), a developmental disorder caused by triplication of chromosome 21, is characterized by deficient cognition and inevitable development of the alzheimer disease (ad) type pathology during aging. |
2015-12-29 |
2023-08-13 |
mouse |
| Ozlem Izci Ay, Mustafa Ertan Ay, Mehmet Emin Erdal, Filiz Cayan, Sevinc Tekin, Fatma Soylemez, Mehmet Ali Sungur, Didem Derici Yıldırı. Folate metabolism gene polymorphisms and risk for down syndrome offspring in Turkish women. Genetic testing and molecular biomarkers. vol 19. issue 4. 2015-12-29. PMID:25671679. |
down syndrome (ds) is the most common chromosomal abnormality. |
2015-12-29 |
2023-08-13 |
Not clear |
| Véronique Brault, Arnaud Duchon, Caroline Romestaing, Ignasi Sahun, Stéphanie Pothion, Mona Karout, Christelle Borel, Doulaye Dembele, Jean-Charles Bizot, Nadia Messaddeq, Andrew J Sharp, Damien Roussel, Stylianos E Antonarakis, Mara Dierssen, Yann Héraul. Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region. PLoS genetics. vol 11. issue 3. 2015-12-28. PMID:25803843. |
the trisomy of human chromosome 21 (hsa21), which causes down syndrome (ds), is the most common viable human aneuploidy. |
2015-12-28 |
2023-08-13 |
mouse |
| Jeroen L A Pennings, Sandra Imholz, Ilse Zutt, Maria P H Koster, Jacqueline E Siljee, Annemieke de Vries, Peter C J I Schielen, Wendy Rodenbur. Predictive performance of a seven-plex antibody array in prenatal screening for Down Syndrome. Disease markers. vol 2015. 2015-12-24. PMID:25983373. |
we evaluated the use of multiplex antibody array methodology for simultaneous measurement of serum protein markers for first trimester screening of down syndrome (ds) and other pregnancy outcomes such as preeclampsia. |
2015-12-24 |
2023-08-13 |
human |
| Nathan P Cramer, Xiufen Xu, Tarik F Haydar, Zygmunt Galdzick. Altered intrinsic and network properties of neocortical neurons in the Ts65Dn mouse model of Down syndrome. Physiological reports. vol 3. issue 12. 2015-12-24. PMID:26702072. |
all individuals with down syndrome (ds) have a varying but significant degree of cognitive disability. |
2015-12-24 |
2023-08-13 |
mouse |
| Silvina Catuara-Solarz, Jose Espinosa-Carrasco, Ionas Erb, Klaus Langohr, Cedric Notredame, Juan R Gonzalez, Mara Diersse. Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome. Frontiers in behavioral neuroscience. vol 9. 2015-12-23. PMID:26696850. |
down syndrome (ds) individuals present increased risk for alzheimer's disease (ad) neuropathology and ad-type dementia. |
2015-12-23 |
2023-08-13 |
mouse |
| Elena Biagi, Marco Candela, Manuela Centanni, Clarissa Consolandi, Simone Rampelli, Silvia Turroni, Marco Severgnini, Clelia Peano, Alessandro Ghezzo, Maria Scurti, Stefano Salvioli, Claudio Franceschi, Patrizia Brigid. Gut microbiome in Down syndrome. PloS one. vol 9. issue 11. 2015-12-21. PMID:25386941. |
premature aging seriously compromises the health status of down syndrome (ds) persons. |
2015-12-21 |
2023-08-13 |
human |
| Devsmita Das, Brian Medina, Mehmet Akif Baktir, Fatemeh S Mojabi, Atoossa Fahimi, Ravikumar Ponnusamy, Ahmad Saleh. Increased incidence of intermittent hypoxemia in the Ts65Dn mouse model of Down syndrome. Neuroscience letters. vol 604. 2015-12-21. PMID:26240993. |
in addition to nervous system, cardiovascular and respiratory systems are primarily affected in down syndrome (ds). |
2015-12-21 |
2023-08-13 |
mouse |
| Miguel A Alcántara-Ortigoza, Jesús De Rubens-Figueroa, Miriam E Reyna-Fabian, Bernardette Estandía-Ortega, Ariadna González-del Angel, Bertha Molina-Álvarez, José A Velázquez-Aragón, Sandra Villagómez-Martínez, Gabriela I Pereira-López, Víctor Martínez-Cruz, Víctor Cruz-Martínez, Rosa M Álvarez-Gómez, Luisa Díaz-García, Luisa García-Día. Germline mutations in NKX2-5, GATA4, and CRELD1 are rare in a Mexican sample of Down syndrome patients with endocardial cushion and septal heart defects. Pediatric cardiology. vol 36. issue 4. 2015-12-17. PMID:25524324. |
congenital heart defects (chd) are found in ~50 % of down syndrome (ds) patients. |
2015-12-17 |
2023-08-13 |
Not clear |