| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jia Yan, Turgay Ayer, Pinar Keskinocak, Aaron B Caughe. Preference-sensitive risk-cutoff values for prenatal-integrated screening test for Down syndrome. Prenatal diagnosis. vol 35. issue 7. 2016-04-07. PMID:25703335. |
for a pregnant woman considering prenatal screening for early detection of down syndrome (ds), there are at least two major outcomes of interest: undetected ds live births and euploid procedure-related fetal losses. |
2016-04-07 |
2023-08-13 |
Not clear |
| A T Makary, R Testa, B J Tonge, S L Einfeld, C Mohr, K M Gra. Association between adaptive behaviour and age in adults with Down syndrome without dementia: examining the range and severity of adaptive behaviour problems. Journal of intellectual disability research : JIDR. vol 59. issue 8. 2016-04-06. PMID:25414060. |
studies on adaptive behaviour and ageing in adults with down syndrome (ds) (without dementia) have typically analysed age-related change in terms of the total item scores on questionnaires. |
2016-04-06 |
2023-08-13 |
Not clear |
| K Frank, A J Esbense. Fine motor and self-care milestones for individuals with Down syndrome using a Retrospective Chart Review. Journal of intellectual disability research : JIDR. vol 59. issue 8. 2016-04-06. PMID:25533735. |
developmental milestone markers for fine motor and self-care skills among children with down syndrome (ds) are either minimal, anecdotal or out-of date. |
2016-04-06 |
2023-08-13 |
Not clear |
| Suellen Valadares Moura, Francianne Andrade, Isis Q Magalhães, Imaruí Costa, Denise Bousfield Silva, Maria Lydia D'Andrea, Vitória P Pinheiro, Maria Lucia M Lee, Fernando Werneck, Mariana Emerenciano, Maria S Pombo-de-Oliveir. Clinical and molecular epidemiology of neonatal leukemia in Brazil. Leukemia & lymphoma. vol 56. issue 4. 2016-04-04. PMID:24991719. |
there were 42 cases of congenital leukemia associated with down syndrome (ds) and 39 of these cases presented features of acute myeloid leukemia (aml)-m7. |
2016-04-04 |
2023-08-13 |
Not clear |
| b' Ivana Babi\\xc4\\x87 Bo\\xc5\\xbeovi\\xc4\\x87, Aleksandra Stankovi\\xc4\\x87, Maja \\xc5\\xbdivkovi\\xc4\\x87, Jadranka Vranekovi\\xc4\\x87, Miljenko Kapovi\\xc4\\x87, Bojana Brajenovi\\xc4\\x87-Mili\\xc4\\x8. Altered LINE-1 Methylation in Mothers of Children with Down Syndrome. PloS one. vol 10. issue 5. 2016-04-04. PMID:26017139.' |
down syndrome (ds, also known as trisomy 21) most often results from chromosomal nondisjunction during oogenesis. |
2016-04-04 |
2023-08-13 |
Not clear |
| Chia-Yu Chang, Sheng-Mei Chen, Huai-En Lu, Syu-Ming Lai, Ping-Shan Lai, Po-Wen Shen, Pei-Ying Chen, Ching-I Shen, Horng-Jyh Harn, Shinn-Zong Lin, Shiaw-Min Hwang, Hong-Lin S. N-butylidenephthalide attenuates Alzheimer's disease-like cytopathy in Down syndrome induced pluripotent stem cell-derived neurons. Scientific reports. vol 5. 2016-04-01. PMID:25735452. |
down syndrome (ds) patients with early-onset dementia share similar neurodegenerative features with alzheimer's disease (ad). |
2016-04-01 |
2023-08-13 |
Not clear |
| Shanshan Deng, Yanli Zhang, Chundi Xu, Duan M. MicroRNA-125b-2 overexpression represses ectodermal differentiation of mouse embryonic stem cells. International journal of molecular medicine. vol 36. issue 2. 2016-03-30. PMID:26059631. |
mir-125b-2, presented on human chromosome 21, is overexpressed in neurons of individuals with down syndrome (ds) with cognitive impairments. |
2016-03-30 |
2023-08-13 |
mouse |
| C-C J J Chen, S D R Ringenbach, D Crews, P H Kulinna, Eric L Amazee. The association between a single bout of moderate physical activity and executive function in young adults with Down syndrome: a preliminary study. Journal of intellectual disability research : JIDR. vol 59. issue 7. 2016-03-29. PMID:25171600. |
this study was aimed at investigating the impact of a single exercise intervention on executive function in young adults with down syndrome (ds). |
2016-03-29 |
2023-08-13 |
Not clear |
| Annette Karmiloff-Smith, Tamara Al-Janabi, Hana D'Souza, Jurgen Groet, Esha Massand, Kin Mok, Carla Startin, Elizabeth Fisher, John Hardy, Dean Nizetic, Victor Tybulewicz, Andre Strydo. The importance of understanding individual differences in Down syndrome. F1000Research. vol 5. 2016-03-29. PMID:27019699. |
in this article, we first present a summary of the general assumptions about down syndrome (ds) still to be found in the literature. |
2016-03-29 |
2023-08-13 |
Not clear |
| Diego Real de Asua, Pedro Parra, Ramón Costa, Fernando Moldenhauer, Carmen Suare. Evaluation of the impact of abdominal obesity on glucose and lipid metabolism disorders in adults with Down syndrome. Research in developmental disabilities. vol 35. issue 11. 2016-03-28. PMID:25108610. |
we aimed to describe anthropometric differences in weight-related disorders between adults with down syndrome (ds) and healthy controls, as well as their disparate impact on glucose and lipid metabolism disorders. |
2016-03-28 |
2023-08-13 |
Not clear |
| Marie Moore Channell, Angela John Thurman, Sara Teresa Kover, Leonard Abbedut. Patterns of change in nonverbal cognition in adolescents with Down syndrome. Research in developmental disabilities. vol 35. issue 11. 2016-03-28. PMID:25112795. |
this study was designed to examine longitudinal change in nonverbal cognitive abilities across adolescence for 20 males with down syndrome (ds). |
2016-03-28 |
2023-08-13 |
human |
| Elizabeth Smith, Christopher Jarrol. Grouping, semantic relation and imagery effects in individuals with Down syndrome. Research in developmental disabilities. vol 35. issue 11. 2016-03-28. PMID:25151606. |
down syndrome (ds) is associated with a specific verbal short-term memory (stm) deficit. |
2016-03-28 |
2023-08-13 |
human |
| Alexis Bosman, Audrey Letourneau, Laura Sartiani, Martina Del Lungo, Flavio Ronzoni, Rostyslav Kuziakiv, Virpi Tohonen, Marco Zucchelli, Federico Santoni, Michel Guipponi, Biljana Dumevska, Outi Hovatta, Stylianos E Antonarakis, Marisa E Jacon. Perturbations of heart development and function in cardiomyocytes from human embryonic stem cells with trisomy 21. Stem cells (Dayton, Ohio). vol 33. issue 5. 2016-03-28. PMID:25645121. |
congenital heart defects (chd) occur in approximately 50% of patients with down syndrome (ds); the mechanisms for this occurrence however remain unknown. |
2016-03-28 |
2023-08-13 |
human |
| Clara Higuera, Katheleen J Gardiner, Krzysztof J Cio. Self-Organizing Feature Maps Identify Proteins Critical to Learning in a Mouse Model of Down Syndrome. PloS one. vol 10. issue 6. 2016-03-28. PMID:26111164. |
down syndrome (ds) is a chromosomal abnormality (trisomy of human chromosome 21) associated with intellectual disability and affecting approximately one in 1000 live births worldwide. |
2016-03-28 |
2023-08-13 |
mouse |
| Lily Jiménez, Jaime Cerda, Gigliola Alberti, Macarena Lizam. [High rates of overweight and obesity in Chilean children with Down syndrome]. Revista medica de Chile. vol 143. issue 4. 2016-03-28. PMID:26204536. |
overweight and obesity in down syndrome (ds) is a common problem. |
2016-03-28 |
2023-08-13 |
Not clear |
| Inês Marques, Ana Silva, Sofia Castro, Lurdes Lope. Down syndrome, insulin-dependent diabetes mellitus and hyperthyroidism: a rare association. BMJ case reports. vol 2015. 2016-03-23. PMID:26123455. |
the association between down syndrome (ds) and autoimmune endocrinopathies is well established. |
2016-03-23 |
2023-08-13 |
Not clear |
| Antonella Izzo, Rosanna Manco, Ferdinando Bonfiglio, Gaetano Calì, Tiziana De Cristofaro, Simone Patergnani, Rita Cicatiello, Rosella Scrima, Mariastella Zannini, Paolo Pinton, Anna Conti, Lucio Nitsc. NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome. Human molecular genetics. vol 23. issue 16. 2016-03-22. PMID:24698981. |
mitochondrial dysfunction, which is consistently observed in down syndrome (ds) cells and tissues, might contribute to the severity of the ds phenotype. |
2016-03-22 |
2023-08-13 |
human |
| Talita Fortunato-Tavares, Claudia R F Andrade, Debora Befi-Lopes, Suelly O Limongi, Fernanda D M Fernandes, Richard G Schwart. Syntactic comprehension and working memory in children with specific language impairment, autism or Down syndrome. Clinical linguistics & phonetics. vol 29. issue 7. 2016-03-21. PMID:25901467. |
this study examined syntactic assignment for predicates and reflexives as well as working memory effects in the sentence comprehension of children with specific language impairment (sli), down syndrome (ds), high functioning autism (hfa) and typical language development (tld). |
2016-03-21 |
2023-08-13 |
Not clear |
| Aoife Murray, Audrey Letourneau, Claudia Canzonetta, Elisavet Stathaki, Stefania Gimelli, Frederique Sloan-Bena, Robert Abrehart, Pollyanna Goh, Shuhui Lim, Chiara Baldo, Franca Dagna-Bricarelli, Saad Hannan, Martin Mortensen, David Ballard, Denise Syndercombe Court, Noemi Fusaki, Mamoru Hasegawa, Trevor G Smart, Cleo Bishop, Stylianos E Antonarakis, Jürgen Groet, Dean Nizeti. Brief report: isogenic induced pluripotent stem cell lines from an adult with mosaic down syndrome model accelerated neuronal ageing and neurodegeneration. Stem cells (Dayton, Ohio). vol 33. issue 6. 2016-03-15. PMID:25694335. |
trisomy 21 (t21), down syndrome (ds) is the most common genetic cause of dementia and intellectual disability. |
2016-03-15 |
2023-08-13 |
human |
| Ambreen Asim, Ashok Kumar, Srinivasan Muthuswamy, Shalu Jain, Sarita Agarwa. "Down syndrome: an insight of the disease". Journal of biomedical science. vol 22. 2016-03-15. PMID:26062604. |
down syndrome (ds) is one of the commonest disorders with huge medical and social cost. |
2016-03-15 |
2023-08-13 |
Not clear |