| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antonio Rodríguez-Núñez, Alexandra Regueiro-García, Cristina Jorge-Soto, Janali Cañas-González, Pilar Leboráns-Iglesias, Oswaldo García-Crespo, Roberto Barcala-Furelo. Quality of chest compressions by Down syndrome people: a pilot trial. Resuscitation. vol 89. 2016-02-12. PMID:25637696. |
down syndrome (ds) citizens have improved their active engagement in society. |
2016-02-12 |
2023-08-13 |
Not clear |
| Emily K Farran, Harry R M Purser, Yannick Courbois, Marine Ballé, Pascal Sockeel, Daniel Mellier, Mark Blade. Route knowledge and configural knowledge in typical and atypical development: a comparison of sparse and rich environments. Journal of neurodevelopmental disorders. vol 7. 2016-02-12. PMID:26870305. |
individuals with down syndrome (ds) and individuals with williams syndrome (ws) have poor navigation skills, which impact their potential to become independent. |
2016-02-12 |
2023-08-13 |
Not clear |
| Steve Horvath, Paolo Garagnani, Maria Giulia Bacalini, Chiara Pirazzini, Stefano Salvioli, Davide Gentilini, Anna Maria Di Blasio, Cristina Giuliani, Spencer Tung, Harry V Vinters, Claudio Francesch. Accelerated epigenetic aging in Down syndrome. Aging cell. vol 14. issue 3. 2016-02-10. PMID:25678027. |
down syndrome (ds) entails an increased risk of many chronic diseases that are typically associated with older age. |
2016-02-10 |
2023-08-13 |
Not clear |
| Md Mahiuddin Ahmed, A Ranjitha Dhanasekaran, Aaron Block, Suhong Tong, Alberto C S Costa, Melissa Stasko, Katheleen J Gardine. Protein dynamics associated with failed and rescued learning in the Ts65Dn mouse model of Down syndrome. PloS one. vol 10. issue 3. 2016-02-09. PMID:25793384. |
down syndrome (ds) is caused by an extra copy of human chromosome 21 (hsa21). |
2016-02-09 |
2023-08-13 |
mouse |
| Stephen I Deutsch, Jessica A Burket, Maria R Urbano, Andrew D Benso. The α7 nicotinic acetylcholine receptor: A mediator of pathogenesis and therapeutic target in autism spectrum disorders and Down syndrome. Biochemical pharmacology. vol 97. issue 4. 2016-02-09. PMID:26074265. |
adults with down syndrome (ds) display a progressive worsening of adaptive functioning, which is associated with alzheimer's disease (ad)-like histopathological changes in brain. |
2016-02-09 |
2023-08-13 |
Not clear |
| Tommaso Aversa, Fortunato Lombardo, Mariella Valenzise, Maria Francesca Messina, Concetta Sferlazzas, Giuseppina Salzano, Filippo De Luca, Malgorzata Wasniewsk. Peculiarities of autoimmune thyroid diseases in children with Turner or Down syndrome: an overview. Italian journal of pediatrics. vol 41. 2016-02-08. PMID:25971674. |
aim of this commentary is to summarize the salient literature news on the relationships between autoimmune thyroid diseases (atds) and either down syndrome (ds) or turner syndrome (ts).according to literature reports both hashimoto's thyroiditis (ht) and graves' disease (gd) are more frequent in children with ds or ts than in those without these chromosomopathies.an up-regulation of proinflammatory cytokines might be responsible for the enhanced susceptibility of ts children to atds, whereas a dysregulation of immune system may favor the development of atds in ds.in ts children biochemical presentation of ht is less severe than in peer controls. |
2016-02-08 |
2023-08-13 |
Not clear |
| Anna Ashworth, Catherine M Hill, Annette Karmiloff-Smith, Dagmara Dimitrio. The Importance of Sleep: Attentional Problems in School-Aged Children With Down Syndrome and Williams Syndrome. Behavioral sleep medicine. vol 13. issue 6. 2016-02-04. PMID:25127421. |
the present study investigated this association in school-aged children with down syndrome (ds) and williams syndrome (ws). |
2016-02-04 |
2023-08-13 |
Not clear |
| Rachel Weitzdoerfer, Nuria Toran, Saraswathi Subramaniyan, Arnold Pollak, Mara Dierssen, Gert Lube. A cluster of protein kinases and phosphatases modulated in fetal Down syndrome (trisomy 21) brain. Amino acids. vol 47. issue 6. 2016-02-04. PMID:25740605. |
down syndrome (ds; trisomy 21) is the most frequent cause of mental retardation with major cognitive and behavioral deficits. |
2016-02-04 |
2023-08-13 |
human |
| Benjamin Wilson, Kyle Bradford Jones, Dean Weedon, Deborah Bilde. Care of Adults With Intellectual and Developmental Disabilities: Down Syndrome. FP essentials. vol 439. 2016-02-02. PMID:26669211. |
down syndrome (ds) is a genetic disorder involving excess genetic material from chromosome 21. |
2016-02-02 |
2023-08-13 |
Not clear |
| Marion K Mateos, Draga Barbaric, Sally-Anne Byatt, Rosemary Sutton, Glenn M Marshal. Down syndrome and leukemia: insights into leukemogenesis and translational targets. Translational pediatrics. vol 4. issue 2. 2016-02-02. PMID:26835364. |
children with down syndrome (ds) have a significantly increased risk of childhood leukemia, in particular acute megakaryoblastic leukemia (amkl) and acute lymphoblastic leukemia (ds-all). |
2016-02-02 |
2023-08-13 |
Not clear |
| Marion K Mateos, Draga Barbaric, Sally-Anne Byatt, Rosemary Sutton, Glenn M Marshal. Down syndrome and leukemia: insights into leukemogenesis and translational targets. Translational pediatrics. vol 4. issue 2. 2016-02-02. PMID:26835364. |
amkl and mds occurring in young children with ds and a gata1 somatic mutation are collectively termed myeloid leukemia of down syndrome (ml-ds). |
2016-02-02 |
2023-08-13 |
Not clear |
| Bruna Lancia Zampieri, Joice Matos Biselli-Périco, Jorge Estefano Santana de Souza, Matheus Carvalho Bürger, Wilson Araújo Silva Júnior, Eny Maria Goloni-Bertollo, Erika Cristina Pavarin. Altered expression of immune-related genes in children with Down syndrome. PloS one. vol 9. issue 9. 2016-01-22. PMID:25222269. |
individuals with down syndrome (ds) have a high incidence of immunological alterations with increased susceptibility to bacterial and viral infections and high frequency of different types of hematologic malignancies and autoimmune disorders. |
2016-01-22 |
2023-08-13 |
human |
| Farah Salwa Abdul Rahim, Alizae Marny Mohamed, Murshida Marizan Nor, Roslan Sau. Dental care access among individuals with Down syndrome: a Malaysian scenario. Acta odontologica Scandinavica. vol 72. issue 8. 2016-01-20. PMID:25029211. |
the purpose of this cross-sectional study was to assess the legal representatives' perceptions on dental care access of individuals with down syndrome (ds) compared to their non-ds siblings in peninsular malaysia. |
2016-01-20 |
2023-08-13 |
Not clear |
| Petrus J W Naudé, Alain D Dekker, Antonia M W Coppus, Yannick Vermeiren, Ulrich L M Eisel, Cornelia M van Duijn, Debby Van Dam, Peter P De Dey. Serum NGAL is Associated with Distinct Plasma Amyloid-β Peptides According to the Clinical Diagnosis of Dementia in Down Syndrome. Journal of Alzheimer's disease : JAD. vol 45. issue 3. 2016-01-19. PMID:25613101. |
the majority of people with down syndrome (ds) develop dementia due to alzheimer's disease (ad). |
2016-01-19 |
2023-08-13 |
Not clear |
| Renata Bartesaghi, Tarik F Haydar, Jean Maurice Delabar, Mara Dierssen, Carmen Martínez-Cué, Diana W Bianch. New Perspectives for the Rescue of Cognitive Disability in Down Syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 41. 2016-01-19. PMID:26468184. |
down syndrome (ds) is a relatively common genetic condition caused by the triplication of human chromosome 21. |
2016-01-19 |
2023-08-13 |
mouse |
| Drupad K Trivedi, Ray K Ile. Shotgun metabolomic profiles in maternal urine identify potential mass spectral markers of abnormal fetal biochemistry - dihydrouracil and progesterone in the metabolism of Down syndrome. Biomedical chromatography : BMC. vol 29. issue 8. 2016-01-15. PMID:25545476. |
in down syndrome (ds) in particular, the precise cellular mechanisms linking genotype to phenotype is not straightforward despite a clear mapping of the genetic cause. |
2016-01-15 |
2023-08-13 |
Not clear |
| Gabriella R Sterne, Jung Hwan Kim, Bing Y. Dysregulated Dscam levels act through Abelson tyrosine kinase to enlarge presynaptic arbors. eLife. vol 4. 2016-01-14. PMID:25988807. |
increased expression of down syndrome cell adhesion molecule (dscam) is implicated in the pathogenesis of brain disorders such as down syndrome (ds) and fragile x syndrome (fxs). |
2016-01-14 |
2023-08-13 |
drosophila_melanogaster |
| Aline Christine das Neves Cardoso, Ana Carolina de Campos, Mariana Martins dos Santos, Denise Castilho Cabrera Santos, Nelci Adriana Cicuto Ferreira Roch. Motor performance of children with Down syndrome and typical development at 2 to 4 and 26 months. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 27. issue 2. 2016-01-13. PMID:25695190. |
to compare gross motor performance of children with down syndrome (ds) and typical development (td) at 2 to 4 months (phase i) and at 2 years of age (phase ii) and to investigate the relation between early motor performance and later outcome. |
2016-01-13 |
2023-08-13 |
Not clear |
| Karen M Chisholm, Claudia V Rivetta, Amy Heerema-McKenne. PRAME immunohistochemical staining in transient abnormal myelopoiesis and myeloid leukemia associated with Down syndrome. Annals of clinical and laboratory science. vol 45. issue 2. 2016-01-13. PMID:25887863. |
transient abnormal myelopoiesis (tam) and myeloid leukemia associated with down syndrome (ml of ds) have morphologically indistinguishable blasts. |
2016-01-13 |
2023-08-13 |
Not clear |
| Bruna Barboza Seron, Karla Fabiana Goessler, Everaldo Lambert Modesto, Eloise Werle Almeida, Márcia Greguo. Blood Pressure and Hemodynamic Adaptations after a Training Program in Young Individuals with Down Syndrome. Arquivos brasileiros de cardiologia. vol 104. issue 6. 2016-01-08. PMID:26131704. |
individuals with down syndrome (ds) have an up to sixteen-time greater risk of mortality from cardiovascular diseases. |
2016-01-08 |
2023-08-13 |
Not clear |