| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deepa Singal, Marni Brownell, Dan Chateau, Chelsea Ruth, Laurence Y Kat. Neonatal and childhood neurodevelopmental, health and educational outcomes of children exposed to antidepressants and maternal depression during pregnancy: protocol for a retrospective population-based cohort study using linked administrative data. BMJ open. vol 6. issue 11. 2017-11-28. PMID:27899401. |
to address this gap, this study will investigate short-term and long-term neurodevelopmental, physical and mental health, and educational outcomes of children who have been exposed to selective serotonin reuptake inhibitors (ssris) or selective serotonin norepinephrine reuptake inhibitors (snris) and/or maternal depression during pregnancy. |
2017-11-28 |
2023-08-13 |
Not clear |
| Zrnka Kovacic Petrovic, Gordana Nedic Erjavec, Matea Nikolac Perkovic, Tina Peraica, Nela Piva. No association between the serotonin transporter linked polymorphic region polymorphism and severity of posttraumatic stress disorder symptoms in combat veterans with or without comorbid depression. Psychiatry research. vol 244. 2017-11-27. PMID:27525827. |
no association between the serotonin transporter linked polymorphic region polymorphism and severity of posttraumatic stress disorder symptoms in combat veterans with or without comorbid depression. |
2017-11-27 |
2023-08-13 |
Not clear |
| Zrnka Kovacic Petrovic, Gordana Nedic Erjavec, Matea Nikolac Perkovic, Tina Peraica, Nela Piva. No association between the serotonin transporter linked polymorphic region polymorphism and severity of posttraumatic stress disorder symptoms in combat veterans with or without comorbid depression. Psychiatry research. vol 244. 2017-11-27. PMID:27525827. |
since both posttraumatic stress disorder (ptsd) and depression are associated with disturbances in the serotoninergic system, the aim of the study was to determine the association between severity of ptsd symptoms, serotonin transporter polymorphism (5-httlpr) and platelet serotonin (5-ht) concentration, in male combat veterans with ptsd (n = 325), who were subdivided according to presence of comorbid depression. |
2017-11-27 |
2023-08-13 |
Not clear |
| Koji Masuda, Mari Nakanishi, Kana Okamoto, Chiwa Kawashima, Harumi Oshita, Ayako Inoue, Fuku Takita, Toshihiko Izumi, Yoshinobu Ishitobi, Haruka Higuma, Masayuki Kanehisa, Taiga Ninomiya, Yoshinori Tanaka, Jotaro Akiyosh. Different functioning of prefrontal cortex predicts treatment response after a selective serotonin reuptake inhibitor treatment in patients with major depression. Journal of affective disorders. vol 214. 2017-11-27. PMID:28266320. |
different functioning of prefrontal cortex predicts treatment response after a selective serotonin reuptake inhibitor treatment in patients with major depression. |
2017-11-27 |
2023-08-13 |
Not clear |
| Hafsteinn Rannversson, Jacob Andersen, Benny Bang-Andersen, Kristian Strømgaar. Mapping the Binding Site for Escitalopram and Paroxetine in the Human Serotonin Transporter Using Genetically Encoded Photo-Cross-Linkers. ACS chemical biology. vol 12. issue 10. 2017-11-20. PMID:28910072. |
in spite of the important role of the human serotonin transporter (hsert) in depression treatment, the molecular details of how antidepressant drugs bind are still not completely understood, in particular those related to potential high- and low-affinity binding sites in hsert. |
2017-11-20 |
2023-08-13 |
human |
| Y A de Vries, A M Roest, M Franzen, M R Munafò, J A Bastiaanse. Citation bias and selective focus on positive findings in the literature on the serotonin transporter gene (5-HTTLPR), life stress and depression. Psychological medicine. vol 46. issue 14. 2017-11-17. PMID:27515846. |
citation bias and selective focus on positive findings in the literature on the serotonin transporter gene (5-httlpr), life stress and depression. |
2017-11-17 |
2023-08-13 |
Not clear |
| P M Fisher, B Ozenne, C Svarer, D Adamsen, S Lehel, W F C Baaré, P S Jensen, G M Knudse. BDNF val66met association with serotonin transporter binding in healthy humans. Translational psychiatry. vol 7. issue 2. 2017-11-16. PMID:28195567. |
the serotonin transporter (5-htt) is a key feature of the serotonin system, which is involved in behavior, cognition and personality and implicated in neuropsychiatric illnesses including depression. |
2017-11-16 |
2023-08-13 |
Not clear |
| D Weissmann, S van der Laan, M D Underwood, N Salvetat, L Cavarec, L Vincent, F Molina, J J Mann, V Arango, J F Pujo. Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression. Translational psychiatry. vol 6. issue 8. 2017-11-13. PMID:27576167. |
region-specific alterations of a-to-i rna editing of serotonin 2c receptor in the cortex of suicides with major depression. |
2017-11-13 |
2023-08-13 |
Not clear |
| Chuan-Chia Chang, Hsin-An Chang, Wen-Hui Fang, Tieh-Ching Chang, San-Yuan Huan. Gender-specific association between serotonin transporter polymorphisms (5-HTTLPR and rs25531) and neuroticism, anxiety and depression in well-defined healthy Han Chinese. Journal of affective disorders. vol 207. 2017-11-09. PMID:27788383. |
gender-specific association between serotonin transporter polymorphisms (5-httlpr and rs25531) and neuroticism, anxiety and depression in well-defined healthy han chinese. |
2017-11-09 |
2023-08-13 |
Not clear |
| L Zhou, S L Ma, P K K Yeung, Y H Wong, K W K Tsim, K F So, L C W Lam, S K Chun. Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac. Translational psychiatry. vol 6. issue 9. 2017-11-07. PMID:27598965. |
anxiety and depression with neurogenesis defects in exchange protein directly activated by camp 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, prozac. |
2017-11-07 |
2023-08-13 |
mouse |
| L Zhou, S L Ma, P K K Yeung, Y H Wong, K W K Tsim, K F So, L C W Lam, S K Chun. Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac. Translational psychiatry. vol 6. issue 9. 2017-11-07. PMID:27598965. |
intracellular camp and serotonin are important modulators of anxiety and depression. |
2017-11-07 |
2023-08-13 |
mouse |
| I Lopez-Vilchez, M Diaz-Ricart, V Navarro, S Torramade, J Zamorano-Leon, A Lopez-Farre, A M Galan, C Gasto, G Escola. Endothelial damage in major depression patients is modulated by SSRI treatment, as demonstrated by circulating biomarkers and an in vitro cell model. Translational psychiatry. vol 6. issue 9. 2017-11-07. PMID:27598970. |
we evaluated circulating biomarkers of endothelial dysfunction in patients with major depression at their diagnosis (md-0) and during antidepressant treatment with the selective serotonin reuptake inhibitor escitalopram, for 8 and 24 weeks (md-8 and md-24). |
2017-11-07 |
2023-08-13 |
human |
| Q S Li, C Tian, G R Seabrook, W C Drevets, V A Naraya. Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Translational psychiatry. vol 6. issue 9. 2017-11-07. PMID:27622933. |
using the phenotype data collected from 23andme 'antidepressant efficacy and side effects' survey and genotype data from 23andme's research participants, we conducted genome-wide association study (gwas) on subjects of european ancestry using four groups of phenotypes (a) non-treatment-resistant depression (n=7795) vs treatment-resistant depression (trd, n=1311), (b) selective serotonin reuptake inhibitors (ssri) responders (n=6348) vs non-responders (n=3340), (c) citalopram/escitalopram responders (n=2963) vs non-responders (n=2005), and (d) norepinephrine-dopamine reuptake inhibitor (ndri, bupropion) responders (n=2675) vs non-responders (n=1861). |
2017-11-07 |
2023-08-13 |
human |
| Rick H A van der Doelen, Berit Robroch, Ilse A Arnoldussen, Maya Schulpen, Judith R Homberg, Tamás Kozic. Serotonin and urocortin 1 in the dorsal raphe and Edinger-Westphal nuclei after early life stress in serotonin transporter knockout rats. Neuroscience. vol 340. 2017-11-07. PMID:27826101. |
the interaction of early life stress (els) and the serotonin transporter (5-htt) gene-linked polymorphic region (5-httlpr) has been associated with increased risk to develop depression in later life. |
2017-11-07 |
2023-08-13 |
rat |
| Edyta Możdżeń, Agnieszka Wąsik, Irena Romańska, Jerzy Michaluk, Lucyna Antkiewicz-Michalu. Antidepressant-like effect of 1,2,3,4-tetrahydroisoquinoline and its methyl derivative in animal models of depression. Pharmacological reports : PR. vol 69. issue 3. 2017-11-07. PMID:28364697. |
most of the currently used antidepressant drugs are monoamine-based compounds, acting by the inhibition of re-uptake or metabolism of noradrenaline (na) and/or serotonin (5-ht), because these neurotransmitters play a key role in the pathophysiology of depression. |
2017-11-07 |
2023-08-13 |
Not clear |
| Jinyu Xiao, Meiying Song, Fengdan Li, Xiaofeng Liu, Alinur Anwar, Hua Zha. Effects of GABA microinjection into dorsal raphe nucleus on behavior and activity of lateral habenular neurons in mice. Experimental neurology. vol 298. issue Pt A. 2017-11-06. PMID:28843542. |
the lateral habenular nucleus (lhb) has been shown to inhibit the activity of drn 5-ht neurons, and thus the lhb-drn pathway plays an important role in the pathogenesis of depression. |
2017-11-06 |
2023-08-13 |
mouse |
| Carol A Shively, Marnie Silverstein-Metzler, Jamie Justice, Stephanie L Willar. The impact of treatment with selective serotonin reuptake inhibitors on primate cardiovascular disease, behavior, and neuroanatomy. Neuroscience and biobehavioral reviews. vol 74. issue Pt B. 2017-10-27. PMID:27590831. |
selective serotonin reuptake inhibitor (ssri) use is ubiquitous because they are widely prescribed for a number of disorders in addition to depression. |
2017-10-27 |
2023-08-13 |
monkey |
| Dinara Akhmetshina, Andrei Zakharov, Daria Vinokurova, Azat Nasretdinov, Guzel Valeeva, Roustem Khazipo. The serotonin reuptake inhibitor citalopram suppresses activity in the neonatal rat barrel cortex in vivo. Brain research bulletin. vol 124. 2017-10-26. PMID:27016034. |
previous in vitro studies have suggested that the disruptive effect of excessive serotonin on barrel map formation involves a depression at thalamocortical synapses. |
2017-10-26 |
2023-08-13 |
rat |
| Qiang Zhang, Jing Jing Feng, Shuai Yang, Xiao Feng Liu, Ji Cheng Li, Hua Zha. Lateral habenula as a link between thyroid and serotoninergic system modiates depressive symptoms in hypothyroidism rats. Brain research bulletin. vol 124. 2017-10-26. PMID:27185576. |
the lateral habenula (lhb) is related to both the serotonin and thyroid systems and also plays an important role in the pathogenesis of depression. |
2017-10-26 |
2023-08-13 |
rat |
| Christoph Kraus, Eero Castrén, Siegfried Kasper, Rupert Lanzenberge. Serotonin and neuroplasticity - Links between molecular, functional and structural pathophysiology in depression. Neuroscience and biobehavioral reviews. vol 77. 2017-10-26. PMID:28342763. |
serotonin and neuroplasticity - links between molecular, functional and structural pathophysiology in depression. |
2017-10-26 |
2023-08-13 |
Not clear |