| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jelena Bakusic, Wilmar Schaufeli, Stephan Claes, Lode Godderi. Stress, burnout and depression: A systematic review on DNA methylation mechanisms. Journal of psychosomatic research. vol 92. 2017-08-28. PMID:27998510. |
the serotonin transporter gene (slc6a4) methylation was similarly affected in stress, depression and burnout. |
2017-08-28 |
2023-08-13 |
human |
| Darakhshan Jabeen Halee. Drug Targets for Obesity and Depression: From Serotonin to Leptin. Current drug targets. vol 17. issue 11. 2017-08-22. PMID:26648065. |
drug targets for obesity and depression: from serotonin to leptin. |
2017-08-22 |
2023-08-13 |
Not clear |
| Darakhshan Jabeen Halee. Drug Targets for Obesity and Depression: From Serotonin to Leptin. Current drug targets. vol 17. issue 11. 2017-08-22. PMID:26648065. |
drugs that increase serotonin neurotransmission are commonly recommended for the treatment of depression. |
2017-08-22 |
2023-08-13 |
Not clear |
| Darakhshan Jabeen Halee. Drug Targets for Obesity and Depression: From Serotonin to Leptin. Current drug targets. vol 17. issue 11. 2017-08-22. PMID:26648065. |
these studies may facilitate the development of alternative treatment strategies, beyond serotonin based drugs, for obesity depression and their comorbid condition. |
2017-08-22 |
2023-08-13 |
Not clear |
| Tanveer Singh, Rajesh Kumar Goe. Managing epilepsy-associated depression: Serotonin enhancers or serotonin producers? Epilepsy & behavior : E&B. vol 66. 2017-08-16. PMID:28038393. |
managing epilepsy-associated depression: serotonin enhancers or serotonin producers? |
2017-08-16 |
2023-08-13 |
Not clear |
| Tanveer Singh, Rajesh Kumar Goe. Managing epilepsy-associated depression: Serotonin enhancers or serotonin producers? Epilepsy & behavior : E&B. vol 66. 2017-08-16. PMID:28038393. |
selective serotonin reuptake inhibitors (ssris) are considered as safest therapy for the treatment of depression in pwe. |
2017-08-16 |
2023-08-13 |
Not clear |
| Tanveer Singh, Rajesh Kumar Goe. Managing epilepsy-associated depression: Serotonin enhancers or serotonin producers? Epilepsy & behavior : E&B. vol 66. 2017-08-16. PMID:28038393. |
the potential of various anti-inflammatory approaches such as selective cyclooxygenase-2 inhibitors, inflammatory cytokine inhibitors, and indoleamine 2,3-dioxygenase inhibitors pertaining to their serotonin restoring effects is discussed as possible therapy for treatment of depression in epilepsy. |
2017-08-16 |
2023-08-13 |
Not clear |
| Edward Ofori, Xue Y Zhu, Jagan R Etukala, Barbara A Bricker, Seth Y Ablordeppe. Synthesis and evaluation of the structural elements in alkylated tetrahydroisoquinolines for binding to CNS receptors. Bioorganic & medicinal chemistry. vol 24. issue 22. 2017-08-14. PMID:27717652. |
schizophrenia and depression are examples of such diseases and their pharmacotherapy thus depends on agents which target multiple receptors including the dopamine, serotonin and even cholinergic receptors at the same time. |
2017-08-14 |
2023-08-13 |
Not clear |
| Amanda Eskelund, Yan Li, David P Budac, Heidi K Müller, Maria Gulinello, Connie Sanchez, Gregers Wegene. Drugs with antidepressant properties affect tryptophan metabolites differently in rodent models with depression-like behavior. Journal of neurochemistry. vol 142. issue 1. 2017-08-14. PMID:28407315. |
the metabolism of tryptophan through kynurenine and serotonin pathways is linked to depression. |
2017-08-14 |
2023-08-13 |
mouse |
| A Russo, P Capogrosso, E Ventimiglia, G La Croce, L Boeri, F Montorsi, A Saloni. Efficacy and safety of dapoxetine in treatment of premature ejaculation: an evidence-based review. International journal of clinical practice. vol 70. issue 9. 2017-08-07. PMID:27456527. |
historically, it has been treated with cognitive therapy, behavioural methods and off-label use of selective serotonin reuptake inhibitors (ssris) usually used to treat depression and other psychological disorders. |
2017-08-07 |
2023-08-13 |
Not clear |
| Hans O Kalkman, Dominik Feuerbac. Antidepressant therapies inhibit inflammation and microglial M1-polarization. Pharmacology & therapeutics. vol 163. 2017-07-31. PMID:27101921. |
bh4 is a critical cofactor for the synthesis of dopamine, noradrenaline, and serotonin, and its loss could explain some of the symptoms of depression. |
2017-07-31 |
2023-08-13 |
human |
| Marnie G Silverstein-Metzler, Carol A Shively, Thomas B Clarkson, Susan E Appt, J Jeffrey Carr, Stephen B Kritchevsky, Sara R Jones, Thomas C Registe. Sertraline inhibits increases in body fat and carbohydrate dysregulation in adult female cynomolgus monkeys. Psychoneuroendocrinology. vol 68. 2017-07-28. PMID:26939086. |
selective serotonin reuptake inhibitor (ssri) antidepressants are widely prescribed for depression and other disorders. |
2017-07-28 |
2023-08-13 |
monkey |
| Vivian Bradaschia-Correa, Anne M Josephson, Devan Mehta, Matthew Mizrahi, Shane S Neibart, Chao Liu, Oran D Kennedy, Alesha B Castillo, Kenneth A Egol, Philipp Leuch. The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 32. issue 4. 2017-07-28. PMID:27869327. |
chronic use of selective serotonin reuptake inhibitors (ssris) for the treatment of depression has been linked to osteoporosis. |
2017-07-28 |
2023-08-13 |
mouse |
| M Y Liu, L J Zhan. [Impact of trimetazidine pre-treatment on 5-hydroxytryptamine and serotonin transporter in rats with experimental myocardial infarction and depression]. Zhonghua xin xue guan bing za zhi. vol 45. issue 2. 2017-07-27. PMID:28260320. |
[impact of trimetazidine pre-treatment on 5-hydroxytryptamine and serotonin transporter in rats with experimental myocardial infarction and depression]. |
2017-07-27 |
2023-08-13 |
rat |
| Amanda Eskelund, David P Budac, Connie Sanchez, Betina Elfving, Gregers Wegene. Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism. Neuroscience. vol 329. 2017-07-26. PMID:27210075. |
here we investigated 13 kynurenine and serotonin metabolites in female flinders sensitive line (fsl) rats, a genetic rat model of depression. |
2017-07-26 |
2023-08-13 |
human |
| Bettina Noto, Friederike Klempin, Natalia Alenina, Michael Bader, Heidrun Fink, Svenja E Sande. Increased adult neurogenesis in mice with a permanent overexpression of the postsynaptic 5-HT Neuroscience letters. vol 633. 2017-07-26. PMID:27693660. |
increased adult neurogenesis in mice with a permanent overexpression of the postsynaptic 5-ht depression is among the leading causes of disability and disease burden. |
2017-07-26 |
2023-08-13 |
mouse |
| Aviad Hai, Lili X Cai, Taekwan Lee, Victor S Lelyveld, Alan Jasanof. Molecular fMRI of Serotonin Transport. Neuron. vol 92. issue 4. 2017-07-26. PMID:27773583. |
serotonin reuptake in particular is important for mood regulation and is inhibited by first-line drugs for treatment of depression. |
2017-07-26 |
2023-08-13 |
Not clear |
| Melissa Jones, Laura Acion, Ricardo E Jorg. What are the complications and emerging strategies for preventing depression following traumatic brain injury? Expert review of neurotherapeutics. vol 17. issue 6. 2017-07-26. PMID:28343407. |
areas covered: the authors recently reported on the efficacy of sertraline, a selective serotonin reuptake inhibitor (ssri), for the prevention of new cases of depression in the first six months after tbi. |
2017-07-26 |
2023-08-13 |
Not clear |
| José Carlos Pereira, Márcia Pradella Hallinan, Rosana Cardoso Alve. Secondary to excessive melatonin synthesis, the consumption of tryptophan from outside the blood-brain barrier and melatonin over-signaling in the pars tuberalis may be central to the pathophysiology of winter depression. Medical hypotheses. vol 98. 2017-07-24. PMID:28012610. |
both conditions reduced serotonin production and central hypothyroidism may cause depression. |
2017-07-24 |
2023-08-13 |
Not clear |
| Robert Langan, Andrew J Goodbre. Identification and Management of Peripartum Depression. American family physician. vol 93. issue 10. 2017-07-17. PMID:27175720. |
mild to moderate depression should be treated with psychotherapy or selective serotonin reuptake inhibitors, whereas moderate to severe depression should be treated with a combination of psychotherapy and medication. |
2017-07-17 |
2023-08-13 |
Not clear |