| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kiran Kumar Katakam, Naqash Javaid Sethi, Janus Christian Jakobsen, Christian Gluu. Great boast, small roast on effects of selective serotonin reuptake inhibitors: response to a critique of our systematic review. Acta neuropsychiatrica. vol 30. issue 5. 2019-02-25. PMID:29465026. |
our systematic review in bmc psychiatry concluded that selective serotonin reuptake inhibitors (ssris) compared with placebo significantly increase the risk of serious adverse events (saes) in patients with major depression and the potential beneficial effects of ssris seem to be outweighed by the harms. |
2019-02-25 |
2023-08-13 |
Not clear |
| Xuan Liu, Ge Jin, Bilian Fan, Yang Xing, Lei Wang, Min Wang, Yueming Yuan, Qiwen Zh. The impact of ALDH2 activation by Alda-1 on the expression of VEGF in the hippocampus of a rat model of post-MI depression. Neuroscience letters. vol 674. 2019-02-25. PMID:29574217. |
these behaviors were associated with an increase 5-ht and da neurotransmitter content, as well as an increase of vegf levels in the hippocampus of the post-mi depression rats. |
2019-02-25 |
2023-08-13 |
rat |
| Silvia Vincentiis, Juliana Alcantara, Patricia Rzezak, Daniel S Kerr, Wagner F Gattaz, Helio van der Linden, Bernardo Dos Santos, Sebastiao E Melo-Souza, Francisco Arruda, Paulo Ragazzo, Tiffany Chaim-Avancini, Mauricio H Serpa, Fernando Fernandes, Ricardo A Moreno, Geraldo Busatto, Ruda Alessi, Renata Demarque, Kette D Valent. Genetic polymorphisms of the 5HT receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. Epilepsy & behavior : E&B. vol 83. 2019-02-25. PMID:29709878. |
genetic polymorphisms of the 5ht receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. |
2019-02-25 |
2023-08-13 |
Not clear |
| Fuzhong Yang, Amy Cheung, Jing Tao, Nan Zhao, Wenbin Wan, Jianhua Shen. Physiological dosages of estradiol and diarylpropionitrile decrease depressive behavior and increase tryptophan hydroxylase expression in the dorsal raphe nucleus of rats subjected to the forced swim test. Neuroreport. vol 30. issue 2. 2019-02-25. PMID:30379725. |
the dorsal raphe nucleus (dr) is a crucial source of serotonin (5-ht) neurons involved in the regulation of stress-induced depression. |
2019-02-25 |
2023-08-13 |
rat |
| Justine S Wang, Yvette P Conley, Susan M Sereika, Catherine M Bender, Poorwa Godbole, Susan W Wesmille. Examining the effect of 5-HTTLPR on depressive symptoms in postmenopausal women 1 year after initial breast cancer treatment. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. vol 27. issue 2. 2019-02-21. PMID:29982901. |
the serotonin transporter gene slc6a4 and its functional polymorphism 5-httlpr have been extensively studied as factors in the development of depression. |
2019-02-21 |
2023-08-13 |
Not clear |
| Lejing Lian, Ying Xu, Jianbo Zhang, Yingcong Yu, Naping Zhu, Xiaofei Guan, Hui Huang, Ruijie Chen, Jie Chen, Guilan Shi, Jianchun Pa. Antidepressant-like effects of a novel curcumin derivative J147: Involvement of 5-HT Neuropharmacology. vol 135. 2019-02-20. PMID:29626566. |
antidepressant-like effects of a novel curcumin derivative j147: involvement of 5-ht depression is a dysthymia disorder characterized by a pervasive or persistent mental disorder that causes mood, cognitive and memory deficits. |
2019-02-20 |
2023-08-13 |
Not clear |
| Eric Brown, Conor J Mc Veigh, Leilani Santos, Martina Gogarty, Heidi Kaastrup Müller, Betina Elfving, David J Brayden, Jana Haas. TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis. Neuropharmacology. vol 137. 2019-02-20. PMID:29723540. |
the serotonin transporter (sert) facilitates high affinity reuptake of 5-ht from the extracellular fluid and dysregulation of transporter function has been implicated in a range of mood disorders including depression. |
2019-02-20 |
2023-08-13 |
mouse |
| Eric Brown, Conor J Mc Veigh, Leilani Santos, Martina Gogarty, Heidi Kaastrup Müller, Betina Elfving, David J Brayden, Jana Haas. TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis. Neuropharmacology. vol 137. 2019-02-20. PMID:29723540. |
recent studies have linked immune system activation to depression as well as to altered serotonin transporter activity. |
2019-02-20 |
2023-08-13 |
mouse |
| Gennady G Knyazev, Alexander N Savostyanov, Andrey V Bocharov, Daria V Bazovkina, Ekaterina A Proshin. Resting State Networks Mediate the Effect of Genotype by Environment Interaction on Mental Health. Neuroscience. vol 369. 2019-02-18. PMID:29129791. |
a number of studies have shown that the presence of short (s) allele of the serotonin transporter-linked polymorphic region (5-httlpr) is associated with a higher risk for depression following exposure to stressful life events. |
2019-02-18 |
2023-08-13 |
Not clear |
| Michael Hoggard, Angela Nocera, Kristi Biswas, Michael W Taylor, Richard G Douglas, Benjamin S Bleie. The sinonasal microbiota, neural signaling, and depression in chronic rhinosinusitis. International forum of allergy & rhinology. vol 8. issue 3. 2019-02-14. PMID:29278464. |
in this study we investigated associations between the sinonasal microbiota; local concentrations of the neurotransmitters serotonin, dopamine, and γ-aminobutyric acid (gaba); and depression severity in a cohort of 14 crs patients and 12 healthy controls. |
2019-02-14 |
2023-08-13 |
human |
| Xiao-Fei Chen, Zeng-Liang Jin, Ying Gong, Nan Zhao, Xiao-Yun Wang, Yu-Hua Ran, You-Zhi Zhang, Li-Ming Zhang, Yun-Feng L. 5-HT Neuropharmacology. vol 138. 2019-02-13. PMID:29805118. |
5-ht most current antidepressants are lacking a pro-cognition effect or even impair cognition as a side effect, and there are few effective psychopharmacological options that improve cognitive dysfunction in depression. |
2019-02-13 |
2023-08-13 |
Not clear |
| Jessica A Babb, Sofia E Linnros, Kathryn G Common. Evidence for intact 5-HT Neuropharmacology. vol 141. 2019-02-13. PMID:30170082. |
evidence for intact 5-ht serotonin (5-ht) neurons are strongly implicated in mood disorders such as depression and are importantly regulated by feedback inhibition mediated by 5-ht |
2019-02-13 |
2023-08-13 |
Not clear |
| Heike Rebholz, Eitan Friedman, Julia Castell. Alterations of Expression of the Serotonin 5-HT4 Receptor in Brain Disorders. International journal of molecular sciences. vol 19. issue 11. 2019-02-12. PMID:30428567. |
the serotonin 4 receptor, 5-ht₄r, represents one of seven different serotonin receptor families and is implicated in a variety of physiological functions and their pathophysiological variants, such as mood and depression or anxiety, food intake and obesity or anorexia, or memory and memory loss in alzheimer's disease. |
2019-02-12 |
2023-08-13 |
Not clear |
| Hannah Weinberg-Wolf, Nicholas A Fagan, George M Anderson, Marios Tringides, Olga Dal Monte, Steve W C Chan. The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 7. 2019-02-08. PMID:29463909. |
to better understand serotonin's role in these pathologies, we investigated the role of serotonin in a behavior frequently impaired in depression and anxiety, attention. |
2019-02-08 |
2023-08-13 |
monkey |
| Xiaofeng Zhao, Qian Liu, Suxia Cao, Jianyue Pang, Huijie Zhang, Tingting Feng, Yajie Deng, Jing Yao, Hengfen L. A meta-analysis of selective serotonin reuptake inhibitors (SSRIs) use during prenatal depression and risk of low birth weight and small for gestational age. Journal of affective disorders. vol 241. 2019-01-29. PMID:30153640. |
a meta-analysis of selective serotonin reuptake inhibitors (ssris) use during prenatal depression and risk of low birth weight and small for gestational age. |
2019-01-29 |
2023-08-13 |
Not clear |
| Xiaofeng Zhao, Qian Liu, Suxia Cao, Jianyue Pang, Huijie Zhang, Tingting Feng, Yajie Deng, Jing Yao, Hengfen L. A meta-analysis of selective serotonin reuptake inhibitors (SSRIs) use during prenatal depression and risk of low birth weight and small for gestational age. Journal of affective disorders. vol 241. 2019-01-29. PMID:30153640. |
selective serotonin reuptake inhibitors (ssris) act as the first-line antidepressants prescribed for the treatment of prenatal depression. |
2019-01-29 |
2023-08-13 |
Not clear |
| N Hlavacova, Y Li, A Pehrson, C Sanchez, I Bermudez, A Csanova, D Jezova, M Frankli. Effects of vortioxetine on biomarkers associated with glutamatergic activity in an SSRI insensitive model of depression in female rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 82. 2019-01-22. PMID:29269186. |
the aim of this study was to investigate the antidepressant activity of vortioxetine in a tryptophan (trp) depletion female rat model of depression and compare it to that of paroxetine using doses that fully occupy the serotonin transporter (sert). |
2019-01-22 |
2023-08-13 |
rat |
| Wei-Tsung Kao, Chen-Lin Chang, For-Wey Lun. 5-HTT mRNA level as a potential biomarker of treatment response in patients with major depression in a clinical trial. Journal of affective disorders. vol 238. 2019-01-22. PMID:29957477. |
to investigate whether the serotonin transporter (5-htt or sert or slc6a4) mrna level could be used as a biomarker of treatment response in patients with major depression treated with different antidepressants while controlling related factors. |
2019-01-22 |
2023-08-13 |
Not clear |
| Qiong-Yan Shao, Fei You, Yong-Hua Zhang, Lin-Lin Hu, Wen-Juan Liu, Yi Liu, Jing Li, Sheng-Dong Wang, Ming-Fen Son. CSF miR-16 expression and its association with miR-16 and serotonin transporter in the raphe of a rat model of depression. Journal of affective disorders. vol 238. 2019-01-22. PMID:29957478. |
csf mir-16 expression and its association with mir-16 and serotonin transporter in the raphe of a rat model of depression. |
2019-01-22 |
2023-08-13 |
rat |
| Qiong-Yan Shao, Fei You, Yong-Hua Zhang, Lin-Lin Hu, Wen-Juan Liu, Yi Liu, Jing Li, Sheng-Dong Wang, Ming-Fen Son. CSF miR-16 expression and its association with miR-16 and serotonin transporter in the raphe of a rat model of depression. Journal of affective disorders. vol 238. 2019-01-22. PMID:29957478. |
here we reported the cerebrospinal fluid (csf) mir-16 expression and its association with mir-16 and serotonin transporter (sert) in the raphe of a rat model of depression. |
2019-01-22 |
2023-08-13 |
rat |