| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rita A Maroun, Lisa A Thackeray, Nick Midgle. Meaning and medication: a thematic analysis of depressed adolescents' views and experiences of SSRI antidepressants alongside psychological therapies. BMC psychiatry. vol 18. issue 1. 2019-09-13. PMID:30486802. |
the prescription of selective serotonin re-uptake inhibitors (ssris) for the treatment of depression in adolescents is an issue of worldwide controversy, and evidence regarding their safety and efficacy is inconclusive. |
2019-09-13 |
2023-08-13 |
Not clear |
| Berit Larsson, Dan Mellström, Lisa Johansson, Anna G Nilsson, Mattias Lorentzon, Daniel Sund. Normal Bone Microstructure and Density But Worse Physical Function in Older Women Treated with Selective Serotonin Reuptake Inhibitors, a Cross-Sectional Population-Based Study. Calcified tissue international. vol 103. issue 3. 2019-09-09. PMID:29730704. |
depression in the elderly is today often treated with selective serotonin reuptake inhibitors (ssris) because of their favorable adverse effect profile. |
2019-09-09 |
2023-08-13 |
Not clear |
| Jiook Cha, Guia Guffanti, Jay Gingrich, Ardesheer Talati, Priya Wickramaratne, Myrna Weissman, Jonathan Posne. Effects of Serotonin Transporter Gene Variation on Impulsivity Mediated by Default Mode Network: A Family Study of Depression. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 6. 2019-09-06. PMID:28444137. |
effects of serotonin transporter gene variation on impulsivity mediated by default mode network: a family study of depression. |
2019-09-06 |
2023-08-13 |
human |
| W Weinrebe, A Moutaouakil, K Risz, M Martin, K Jeckelmann, S Goet. [Age 89 years, depression, fall with pelvic fracture, severe confusion - serotonin syndrome : Differential diagnosis, importance of CYP450 and economic considerations]. Zeitschrift fur Gerontologie und Geriatrie. vol 51. issue 5. 2019-08-27. PMID:28421287. |
the work-up of this case showed a typical constellation of pain and depression in old age; however, the pharmaceutical treatment in this case is not atypical and could lead to a severe serotonin syndrome. |
2019-08-27 |
2023-08-13 |
Not clear |
| Narek Israelyan, Andrew Del Colle, Zhishan Li, Yeji Park, Albert Xing, Jacob P R Jacobsen, Ruth Ann Luna, Dane D Jensen, Moneek Madra, Virginia Saurman, Ray Rahim, Rocco Latorre, Kimberly Law, William Carson, Nigel W Bunnett, Marc G Caron, Kara G Margoli. Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression. Gastroenterology. vol 157. issue 2. 2019-08-26. PMID:31071306. |
effects of serotonin and slow-release 5-hydroxytryptophan on gastrointestinal motility in a mouse model of depression. |
2019-08-26 |
2023-08-13 |
mouse |
| Narek Israelyan, Andrew Del Colle, Zhishan Li, Yeji Park, Albert Xing, Jacob P R Jacobsen, Ruth Ann Luna, Dane D Jensen, Moneek Madra, Virginia Saurman, Ray Rahim, Rocco Latorre, Kimberly Law, William Carson, Nigel W Bunnett, Marc G Caron, Kara G Margoli. Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression. Gastroenterology. vol 157. issue 2. 2019-08-26. PMID:31071306. |
we studied mice with an analogous mutation (tph2-r439h), which results in a 60%-80% decrease in levels of 5-ht in the central nervous system and behaviors associated with depression in humans. |
2019-08-26 |
2023-08-13 |
mouse |
| Ankit Srivastava, Priyanka Singh, Hitesh Gupta, Harpreet Kaur, Neha Kanojia, Debleena Guin, Mamta Sood, Rakesh Kumar Chadda, Jyoti Yadav, Divya Vohora, Luciano Saso, Ritushree Kukret. Systems Approach to Identify Common Genes and Pathways Associated with Response to Selective Serotonin Reuptake Inhibitors and Major Depression Risk. International journal of molecular sciences. vol 20. issue 8. 2019-08-19. PMID:31018568. |
systems approach to identify common genes and pathways associated with response to selective serotonin reuptake inhibitors and major depression risk. |
2019-08-19 |
2023-08-13 |
Not clear |
| Asia Afzal, Saara Ahmad, Faiza Agha, Zehra Batool, Saiqa Tabassum, Laraib Liaquat, Sadia Sadir, Amber Nawaz, Saida Haide. Administration of 5-HT-1B agonist ameliorates pseudodementia induced by depression in rats. Pakistan journal of pharmaceutical sciences. vol 31. issue 5(Supplementary). 2019-08-16. PMID:30393230. |
the serotonin hypothesis provides a target model for the treatment of depression and depression-associated memory loss. |
2019-08-16 |
2023-08-13 |
rat |
| Olivia Tania Hernández-Hernández, Lucía Martínez-Mota, José Jaime Herrera-Pérez, Graciela Jiménez-Rubi. Role of Estradiol in the Expression of Genes Involved in Serotonin Neurotransmission: Implications for Female Depression. Current neuropharmacology. vol 17. issue 5. 2019-08-14. PMID:29956632. |
role of estradiol in the expression of genes involved in serotonin neurotransmission: implications for female depression. |
2019-08-14 |
2023-08-13 |
Not clear |
| F Hieronymus, A Lisinski, S Nilsson, E Eriksso. Efficacy of selective serotonin reuptake inhibitors in the absence of side effects: a mega-analysis of citalopram and paroxetine in adult depression. Molecular psychiatry. vol 23. issue 8. 2019-08-12. PMID:29155804. |
efficacy of selective serotonin reuptake inhibitors in the absence of side effects: a mega-analysis of citalopram and paroxetine in adult depression. |
2019-08-12 |
2023-08-13 |
human |
| A S Silva, L V Toffoli, V B Estrada, L F Veríssimo, J Francis-Oliveira, E G Moreira, M V Gomes, G G Pelos. Maternal exposure to fluoxetine during gestation and lactation induces long lasting changes in the DNA methylation profile of offspring's brain and affects the social interaction of rat. Brain research bulletin. vol 142. 2019-07-30. PMID:30236534. |
fluoxetine (flx) is an antidepressant from the selective serotonin reuptake inhibitor class that has largely been used for the treatment of depression in pregnancy. |
2019-07-30 |
2023-08-13 |
rat |
| Christine Wyss, Desmond H Y Tse, Frank Boers, Nadim J Shah, Irene Neuner, Wolfram Kawoh. Association between Cortical GABA and Loudness Dependence of Auditory Evoked Potentials (LDAEP) in Humans. The international journal of neuropsychopharmacology. vol 21. issue 9. 2019-07-29. PMID:29917080. |
serotonin has been shown to be associated with different psychiatric disorders such as depression and schizophrenia. |
2019-07-29 |
2023-08-13 |
human |
| Wei-Yu Zhu, Xia Feng, Jin Wang, Yu-Pan Lu, Xian-Zhe Dong, Ping Li. [Effect of Dingzhi Xiaowan on miR-16 expression and 5-HT reuptake]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 17. 2019-07-29. PMID:30347920. |
firstly, a chronic unpredictable mild moderate stimulation (cums) combined with solitary rising depression rat model was established, the behavior changes were detected after different doses of dz (600, 300, 150 mg·kg⁻¹) given for 3 weeks, high performance liquid chromatography (hplc) was used to detect 5-ht level in hippocampal, pcr method was used to observe the effect of dz on the expression of sert mrna and mir-16 in hippocampus of cums rat. |
2019-07-29 |
2023-08-13 |
rat |
| Phillip J Tully, Ruth Peters, Karine Pérès, Kaarin J Anstey, Christophe Tzouri. Effect of SSRI and calcium channel blockers on depression symptoms and cognitive function in elderly persons treated for hypertension: three city cohort study. International psychogeriatrics. vol 30. issue 9. 2019-07-25. PMID:29559030. |
the objective of this study was to examine the effect of selective serotonin reuptake inhibitor (ssri) therapy augmented with ccb on depression and cognitive decline in an elderly population with hypertension. |
2019-07-25 |
2023-08-13 |
Not clear |
| Zrnka Kovacic Petrovic, Gordana Nedic Erjavec, Matea Nikolac Perkovic, Dubravka Svob Strac, Tina Peraica, Lucija Tudor, Nela Piva. The Association between Serotonin Transporter Polymorphism, Platelet Serotonin Concentration and Insomnia in Non-Depressed Veterans with Posttraumatic Stress Disorder. Psychiatria Danubina. vol 31. issue 1. 2019-07-22. PMID:30948693. |
here, the association of particular sleep disturbances with 5-httlpr genotypes and platelet serotonin (5-ht) concentration was determined simultaneously in veterans with posttraumatic stress disorder (ptsd), who were subdivided into those with or without comorbid depression. |
2019-07-22 |
2023-08-13 |
Not clear |
| Yingxiao Li, Kai-Chun Cheng, Keng-Fan Liu, Wen-Huang Peng, Juei-Tang Cheng, Ho-Shan Ni. Telmisartan Activates PPARδ to Improve Symptoms of Unpredictable Chronic Mild Stress-Induced Depression in Mice. Scientific reports. vol 7. issue 1. 2019-07-17. PMID:29070884. |
major depression is a common mental disorder that has been established to be associated with a decrease in serotonin and/or serotonin transporters in the brain. |
2019-07-17 |
2023-08-13 |
mouse |
| Hui-Juan Jin, Lei Pei, Ya-Nan Li, Hui Zheng, Shuai Yang, Yan Wan, Ling Mao, Yuan-Peng Xia, Quan-Wei He, Man Li, Zhen-Yu Yue, Bo H. Alleviative effects of fluoxetine on depressive-like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression. Scientific reports. vol 7. issue 1. 2019-07-15. PMID:29097744. |
fluoxetine, one of the selective serotonin reuptake inhibitor (ssri) antidepressants, has been thought to be effective for treating post-stroke depression (psd). |
2019-07-15 |
2023-08-13 |
mouse |
| Wei Shi, Yu Han, Xiaofan Guan, Jiahuan Rong, Wenhao Su, Shanjie Zha, Yu Tang, Xueying Du, Guangxu Li. Fluoxetine suppresses the immune responses of blood clams by reducing haemocyte viability, disturbing signal transduction and imposing physiological stress. The Science of the total environment. vol 683. 2019-07-10. PMID:31150888. |
the antidepressant fluoxetine (flx), a selective serotonin reuptake inhibitor, is widely prescribed for the treatment of depression and anxiety disorders. |
2019-07-10 |
2023-08-13 |
cat |
| Joanne Ryan, Marie-Laure Anceli. Genetic and Epigenetic Regulation of the Serotonin Transporter Gene in Late-Life Depression. Journal of geriatric psychiatry and neurology. vol 32. issue 4. 2019-07-03. PMID:31006322. |
genetic and epigenetic regulation of the serotonin transporter gene in late-life depression. |
2019-07-03 |
2023-08-13 |
Not clear |
| Jonathan M Meyer, Michael A Cummings, George Procto. Augmentation of phenelzine with aripiprazole and quetiapine in a treatment-resistant patient with psychotic unipolar depression: case report and literature review. CNS spectrums. vol 22. issue 5. 2019-07-02. PMID:28004621. |
this paper describes the case of a 54-year-old male with a history of psychotic unipolar depression treated with a combination of phenelzine, aripiprazole, and quetiapine, and reviews the 12 published cases of sga-maoi combination therapy with a focus on the pharmacological basis for serotonin syndrome, and the sga mechanisms that should not be associated with a risk for this syndrome. |
2019-07-02 |
2023-08-13 |
Not clear |