| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E L Gibso. Tryptophan supplementation and serotonin function: genetic variations in behavioural effects. The Proceedings of the Nutrition Society. vol 77. issue 2. 2019-01-16. PMID:29368666. |
the neurotransmitter serotonin has a role in affective disorders such as depression and anxiety, as well as sleep, cognitive function and appetite. |
2019-01-16 |
2023-08-13 |
Not clear |
| Natsuki Igata, Shingo Kakeda, Keita Watanabe, Satoru Ide, Taro Kishi, Osamu Abe, Ryouhei Igata, Asuka Katsuki, Nakao Iwata, Reiji Yoshimura, Yukunori Korog. Voxel-based morphometric brain comparison between healthy subjects and major depressive disorder patients in Japanese with the s/s genotype of 5-HTTLPR. Scientific reports. vol 7. issue 1. 2019-01-09. PMID:28638109. |
individuals with s/s genotype of serotonin transporter gene-linked promotor region (5-httlpr), which appear with a high frequency in japanese, exhibit more diagnosable depression in relation to stressful life events than those with the s/l or l/l genotype. |
2019-01-09 |
2023-08-13 |
human |
| Marina P Valerio, Alejandro G Szmulewicz, Diego J Martin. A quantitative review on outcome-to-antidepressants in melancholic unipolar depression. Psychiatry research. vol 265. 2019-01-09. PMID:29702301. |
finally, treatment of melancholic depression with serotonin reuptake inhibitors was associated with lower odds of remission compared with tricyclic antidepressants, and similar outcome compared with venlafaxine. |
2019-01-09 |
2023-08-13 |
Not clear |
| Piotr Gałecki, Monika Talarowsk. Inflammatory theory of depression. Psychiatria polska. vol 52. issue 3. 2019-01-07. PMID:30218560. |
through the kynurenine pathway, these factors lead to a deficit in serotonin and melatonin, which is considered one of the main reasons of depression. |
2019-01-07 |
2023-08-13 |
human |
| Xue Jiao Liu, Li Zhang, Yong Fang Zhang, Wen Xu, Yang Hu, Ying Liu, Jing Ba. Echogenic alteration in the raphe nuclei measured by transcranial sonography in patients with Parkinson disease and depression. Medicine. vol 97. issue 50. 2019-01-04. PMID:30558008. |
the methods used in previous studies lack quantitative and objective indicators to some extent; therefore, the present study used the level of platelet 5-hydroxytryptamine (5-ht) as an objective indicator of depression. |
2019-01-04 |
2023-08-13 |
Not clear |
| Richard Lee-Kelland, Sabeeka Zehra, Pradeesh Mapp. Fluoxetine overdose in a teenager resulting in serotonin syndrome, seizure and delayed onset rhabdomyolysis. BMJ case reports. vol 2018. 2018-12-31. PMID:30301727. |
a 14-year-old young adult took an overdose of 1.2 g of fluoxetine, a selective serotonin reuptake inhibitor (ssri) that he had been prescribed for depression. |
2018-12-31 |
2023-08-13 |
Not clear |
| David T Chau, Phoebe Fogelman, Pia Nordanskog, Wayne C Drevets, J Paul Hamilto. Distinct Neural-Functional Effects of Treatments With Selective Serotonin Reuptake Inhibitors, Electroconvulsive Therapy, and Transcranial Magnetic Stimulation and Their Relations to Regional Brain Function in Major Depression: A Meta-analysis. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 2. issue 4. 2018-12-19. PMID:29560920. |
distinct neural-functional effects of treatments with selective serotonin reuptake inhibitors, electroconvulsive therapy, and transcranial magnetic stimulation and their relations to regional brain function in major depression: a meta-analysis. |
2018-12-19 |
2023-08-13 |
Not clear |
| Hiroyuki Muraoka, Hidehiro Oshibuchi, Masahiko Kawano, Takaaki Kawano, Takahiro Tsutsumi, Makiko Yamada, Jun Ishigooka, Katsuji Nishimura, Ken Inad. Escitalopram attenuates fear stress-induced increase in amygdalar dopamine following methamphetamine-induced sensitisation: Implications of fine-tuning action of selective serotonin reuptake inhibitors on emotional processing. European journal of pharmacology. vol 834. 2018-12-18. PMID:29981749. |
serotonin reuptake inhibitors modulate the serotonergic pathways of the nervous system and are widely used for treating psychiatric conditions such as anxiety and depression. |
2018-12-18 |
2023-08-13 |
rat |
| Xiaoyin Zhuang, Haiyun Xu, Zeman Fang, Chongtao Xu, Chaobiao Xue, Xiaohong Hon. Platelet serotonin and serotonin transporter as peripheral surrogates in depression and anxiety patients. European journal of pharmacology. vol 834. 2018-12-18. PMID:30031795. |
platelet serotonin and serotonin transporter as peripheral surrogates in depression and anxiety patients. |
2018-12-18 |
2023-08-13 |
human |
| Xiaoyin Zhuang, Haiyun Xu, Zeman Fang, Chongtao Xu, Chaobiao Xue, Xiaohong Hon. Platelet serotonin and serotonin transporter as peripheral surrogates in depression and anxiety patients. European journal of pharmacology. vol 834. 2018-12-18. PMID:30031795. |
in this study, platelet 5-ht content and 5-ht uptake capacity of sert in depression and anxiety patients were measured by elisa and flow cytometry with idt307 at baseline and after serotonin reuptake inhibitors (ssris) treatment for 4 weeks. |
2018-12-18 |
2023-08-13 |
human |
| Xiaoyin Zhuang, Haiyun Xu, Zeman Fang, Chongtao Xu, Chaobiao Xue, Xiaohong Hon. Platelet serotonin and serotonin transporter as peripheral surrogates in depression and anxiety patients. European journal of pharmacology. vol 834. 2018-12-18. PMID:30031795. |
compared to healthy subjects, anxiety and depression patients showed higher levels of platelet 5-ht and idt307 fluorescence intensity, but the values were comparable between the patient groups. |
2018-12-18 |
2023-08-13 |
human |
| Xiaoyin Zhuang, Haiyun Xu, Zeman Fang, Chongtao Xu, Chaobiao Xue, Xiaohong Hon. Platelet serotonin and serotonin transporter as peripheral surrogates in depression and anxiety patients. European journal of pharmacology. vol 834. 2018-12-18. PMID:30031795. |
ssris administration for 4 weeks significantly decreased scores of hamd (29 vs 14) and hama (22 vs 14) in depression and anxiety patients, respectively; while it decreased platelet 5-ht content, but did not change the idt307 fluorescence intensity of platelets. |
2018-12-18 |
2023-08-13 |
human |
| Xiaoyin Zhuang, Haiyun Xu, Zeman Fang, Chongtao Xu, Chaobiao Xue, Xiaohong Hon. Platelet serotonin and serotonin transporter as peripheral surrogates in depression and anxiety patients. European journal of pharmacology. vol 834. 2018-12-18. PMID:30031795. |
these results provide further evidence supporting the employment of platelet 5-ht content and sert as peripheral surrogates in depression and anxiety patients, and are of help in understanding the several weeks' delay from the initiation of antidepressant medication to their full therapeutic effects in the patients. |
2018-12-18 |
2023-08-13 |
human |
| Hideto Nakayama, Hiroaki Matayosh. [Management of Preoperative Drugs : Psychotropic Drugs]. Masui. The Japanese journal of anesthesiology. vol 65. issue 11. 2018-12-18. PMID:30351802. |
patients with depression may be predisposed to perioperative problems such as hypotension, serotonin syndrome and discontinuation syndrome. |
2018-12-18 |
2023-08-13 |
Not clear |
| M G Gottschalk, P Mortas, M Haman, S Ozcan, B Biemans, S Bah. Fluoxetine, not donepezil, reverses anhedonia, cognitive dysfunctions and hippocampal proteome changes during repeated social defeat exposure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 1. 2018-12-11. PMID:29174946. |
we evaluated the behavioural and molecular effects of a selective serotonin re-uptake inhibitor (ssri, fluoxetine) and an acetylcholinesterase inhibitor (achei, donepezil) on emotional-cognitive endophenotypes of depression and the hippocampal proteome. |
2018-12-11 |
2023-08-13 |
Not clear |
| Arbind Kumar Choudhary, Yeong Yeh Le. The debate over neurotransmitter interaction in aspartame usage. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 56. 2018-12-11. PMID:30318075. |
altered brain neurochemical compositions [such as dopamine (da), norepinephrine (ne), and serotonin (5-ht)] have long been a concern and being involved in observed neurophysiological symptom (such as headaches, memory loss, mood changes, as well as depression) in aspartame consumers. |
2018-12-11 |
2023-08-13 |
Not clear |
| Martyn J Eckersley, Amir H Sepehripour, Roberto Casula, Prakash Punjabi, Thanos Athanasio. Do selective serotonin reuptake inhibitors increase the risk of bleeding or mortality following coronary artery bypass graft surgery? A meta-analysis of observational studies. Perfusion. vol 33. issue 6. 2018-11-26. PMID:29569518. |
the first line treatment for depression are selective serotonin reuptake inhibitors (ssris) which inhibit serotonin reuptake in the presynaptic neuronal membrane and uptake by platelets, inhibiting subsequent serotonin-mediated platelet activation. |
2018-11-26 |
2023-08-13 |
Not clear |
| Wenrui Ye, Michael Duffy Pitlock, Martin A Javors, Brent J Thompson, James D Lechleiter, Julie G Hensle. The long-term effect of maternal dietary protein restriction on 5-HT Behavioural brain research. vol 349. 2018-11-26. PMID:29660440. |
the long-term effect of maternal dietary protein restriction on 5-ht maternal nutrition impacts fetal development, and may play a role in determining resilience to stress and vulnerability to stress-precipitated psychiatric disorders, such as anxiety and depression. |
2018-11-26 |
2023-08-13 |
Not clear |
| Eeske van Roekel, Maaike Verhagen, Rutger C M E Engels, Peter Kuppen. Variation in the serotonin transporter polymorphism (5-HTTLPR) and inertia of negative and positive emotions in daily life. Emotion (Washington, D.C.). vol 18. issue 2. 2018-11-20. PMID:28569537. |
these findings suggest a possible psychological pathway how the serotonin transporter gene contributes to risk for depression. |
2018-11-20 |
2023-08-13 |
Not clear |
| Justyna Jasionowska, Maria Filip, Monika Talarowska, Piotr Gałeck. [The importance of the kynurenine pathway in depressive disorders]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 45. issue 266. 2018-11-20. PMID:30240376. |
the main methods of antidepressant treatment, in particular the use of serotonin reuptake inhibitors (ssris), take into account the concept of monoamine deficiency in patients with depression. |
2018-11-20 |
2023-08-13 |
human |