| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Dey, R H Singh, P K De. Exercise training: significance of regional alterations in serotonin metabolism of rat brain in relation to antidepressant effect of exercise. Physiology & behavior. vol 52. issue 6. 1993-02-17. PMID:1283013. |
these findings have been discussed in an attempt to explain the antidepressant effect of exercise based on the 5ht deficiency theory of endogenous depression. |
1993-02-17 |
2023-08-11 |
rat |
| S J Warringto. Clinical implications of the pharmacology of serotonin reuptake inhibitors. International clinical psychopharmacology. vol 7 Suppl 2. 1993-02-17. PMID:1484174. |
the similarities between the ssris are more obvious than their differences: all are highly potent and selective inhibitors of serotonin reuptake with efficacy in the treatment of depression. |
1993-02-17 |
2023-08-11 |
Not clear |
| J Mendel. The acute and long-term treatment of major depression. International clinical psychopharmacology. vol 7 Suppl 2. 1993-02-17. PMID:1484175. |
the availability of a new class of antidepressant medications--the selective serotonin reuptake inhibitors (ssris)--heralds a new phase in the treatment of depression. |
1993-02-17 |
2023-08-11 |
Not clear |
| C Thompso. Bridging the gap between psychiatric practice and primary care. International clinical psychopharmacology. vol 7 Suppl 2. 1993-02-17. PMID:1484176. |
however, prescriptions of the selective serotonin reuptake inhibitors (ssris) for depression are gradually increasing here and in other countries such as the usa, france and canada, where the ssris as a class account for upwards of 30% of new antidepressant prescriptions. |
1993-02-17 |
2023-08-11 |
Not clear |
| G Chouinar. Sertraline in the treatment of obsessive compulsive disorder: two double-blind, placebo-controlled studies. International clinical psychopharmacology. vol 7 Suppl 2. 1993-02-17. PMID:1484177. |
sertraline is a non-tricyclic, potent and selective serotonin reuptake inhibitor (ssri) which is currently approved for the treatment of depression in several countries, including the uk and the usa. |
1993-02-17 |
2023-08-11 |
Not clear |
| K P Lesch, C S Aulakh, B L Wolozin, D L Murph. Serotonin (5-HT) receptor, 5-HT transporter and G protein-effector expression: implications for depression. Pharmacology & toxicology. vol 71 Suppl 1. 1993-02-11. PMID:1480560. |
serotonin (5-ht) receptor, 5-ht transporter and g protein-effector expression: implications for depression. |
1993-02-11 |
2023-08-11 |
Not clear |
| S E Mølle. Serotonin, carbohydrates, and atypical depression. Pharmacology & toxicology. vol 71 Suppl 1. 1993-02-11. PMID:1480561. |
serotonin, carbohydrates, and atypical depression. |
1993-02-11 |
2023-08-11 |
rat |
| P Celada, J Pérez, E Alvarez, F Artiga. Monoamine oxidase inhibitors phenelzine and brofaromine increase plasma serotonin and decrease 5-hydroxyindoleacetic acid in patients with major depression: relationship to clinical improvement. Journal of clinical psychopharmacology. vol 12. issue 5. 1993-02-10. PMID:1282522. |
monoamine oxidase inhibitors phenelzine and brofaromine increase plasma serotonin and decrease 5-hydroxyindoleacetic acid in patients with major depression: relationship to clinical improvement. |
1993-02-10 |
2023-08-11 |
Not clear |
| P Celada, J Pérez, E Alvarez, F Artiga. Monoamine oxidase inhibitors phenelzine and brofaromine increase plasma serotonin and decrease 5-hydroxyindoleacetic acid in patients with major depression: relationship to clinical improvement. Journal of clinical psychopharmacology. vol 12. issue 5. 1993-02-10. PMID:1282522. |
plasma 5-ht increased more markedly in responders than in nonresponders and a significant inverse relationship surfaced between plasma 5-ht and the hamilton rating scale for depression. |
1993-02-10 |
2023-08-11 |
Not clear |
| B Mårtensso. [Selective serotonin uptake in depression. Same therapeutic effect as tricyclic agents but better side effect profile and lower toxicity?]. Lakartidningen. vol 89. issue 50. 1993-01-27. PMID:1469979. |
[selective serotonin uptake in depression. |
1993-01-27 |
2023-08-11 |
Not clear |
| R Krulík, Z Fisa. [Adrenergic and serotonergic receptors during depression and its therapy]. Ceskoslovenska psychiatrie. vol 88. issue 5. 1993-01-06. PMID:1451201. |
the hypothesis are based on changes of levels of serotonin and noradrenaline and on changes of their binding sites during depression and its treatment. |
1993-01-06 |
2023-08-11 |
Not clear |
| Selective Serotonin Uptake Inhibitors in Depression and Other Indications. Symposium proceedings. Florence, Italy, 11 June 1991. International clinical psychopharmacology. vol 6 Suppl 5. 1992-12-23. PMID:1358940. |
selective serotonin uptake inhibitors in depression and other indications. |
1992-12-23 |
2023-08-11 |
Not clear |
| T Silverston. New aspects in the treatment of depression. International clinical psychopharmacology. vol 6 Suppl 5. 1992-12-23. PMID:1431020. |
for resistant depression the addition of lithium (and/or tryptophan) may be effective, possibly through promoting 5-ht neurotransmission. |
1992-12-23 |
2023-08-11 |
Not clear |
| T Silverston. New aspects in the treatment of depression. International clinical psychopharmacology. vol 6 Suppl 5. 1992-12-23. PMID:1431020. |
continuous treatment with a selective 5-ht reuptake inhibitor can reduce the relapse rate in patients with recurrent depression. |
1992-12-23 |
2023-08-11 |
Not clear |
| H M Kravitz, R Katz, E Kot, N Helmke, J Fawcet. Biochemical clues to a fibromyalgia-depression link: imipramine binding in patients with fibromyalgia or depression and in healthy controls. The Journal of rheumatology. vol 19. issue 9. 1992-12-23. PMID:1433012. |
both fibromyalgia and depression may be related to disturbed serotonin metabolism, and an association between the 2 disorders has been postulated. |
1992-12-23 |
2023-08-11 |
human |
| S C Risch, C B Nemerof. Neurochemical alterations of serotonergic neuronal systems in depression. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1331029. |
the recent identification and cloning of multiple serotonergic receptor subtypes and the identification and cloning of the serotonin transporter offer further promise for elucidating the role of cns serotonergic neurons in the pathogenesis of depression and, moreover, for the development of innovative treatment strategies for this disorder. |
1992-12-11 |
2023-08-11 |
Not clear |
| V M Linnoila, M Virkkune. Aggression, suicidality, and serotonin. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1385390. |
studies from several countries, representing diverse cultures, have reported an association between violent suicide attempts by patients with unipolar depression and personality disorders and low concentrations of the major serotonin metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the cerebrospinal fluid (csf). |
1992-12-11 |
2023-08-11 |
Not clear |
| A F Schatzberg, A J Rothschil. Serotonin activity in psychotic (delusional) major depression. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1429484. |
serotonin activity in psychotic (delusional) major depression. |
1992-12-11 |
2023-08-11 |
Not clear |
| A F Schatzberg, A J Rothschil. Serotonin activity in psychotic (delusional) major depression. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1429484. |
the implications of these findings vis-à-vis a role for serotonin in delusional major depression are discussed. |
1992-12-11 |
2023-08-11 |
Not clear |
| A F Schatzberg, A J Rothschil. Serotonin activity in psychotic (delusional) major depression. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1429484. |
future studies on serotonin as well as on 5-ht2 antagonists in delusional depression are warranted. |
1992-12-11 |
2023-08-11 |
Not clear |