| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Leira, J Castillo, F Martinez, J M Prieto, M Noy. Platelet-rich plasma serotonin levels in tension-type headache and depression. Cephalalgia : an international journal of headache. vol 13. issue 5. 1993-12-30. PMID:8242728. |
our data suggest that the rise of platelet serotonin levels in tension-type headache is related to pain and not depression. |
1993-12-30 |
2023-08-12 |
Not clear |
| D Mori. Compared effects of serotonin on the inspiratory activity of glossopharyngeal, vagal, hypoglossal and cervical motoneurons in neonatal rat brain stem-spinal cord preparations. Neuroscience letters. vol 160. issue 1. 1993-12-23. PMID:8247335. |
although 5-ht qualitatively depressed all the inspiratory motor outputs, the quantitatively drastic and long-lasting depression of the xii inspiratory activity was particularly noteworthy. |
1993-12-23 |
2023-08-12 |
rat |
| M Briley, C More. Neurobiological mechanisms involved in antidepressant therapies. Clinical neuropharmacology. vol 16. issue 5. 1993-12-22. PMID:8221701. |
selective serotonin reuptake inhibitors (ssris) are effective in alleviating the symptoms of depression. |
1993-12-22 |
2023-08-12 |
Not clear |
| Paroxetine: a new selective serotonin uptake inhibitor for depression. The Nurse practitioner. vol 18. issue 9. 1993-11-24. PMID:8414228. |
paroxetine: a new selective serotonin uptake inhibitor for depression. |
1993-11-24 |
2023-08-12 |
Not clear |
| Selective serotonin reuptake inhibitors for depression? Drug and therapeutics bulletin. vol 31. issue 15. 1993-10-21. PMID:8375273. |
selective serotonin reuptake inhibitors for depression? |
1993-10-21 |
2023-08-12 |
Not clear |
| C J McDougle, W K Goodman, L H Pric. The pharmacotherapy of obsessive-compulsive disorder. Pharmacopsychiatry. vol 26 Suppl 1. 1993-10-20. PMID:8378419. |
although a variety of tricyclic antidepressants and monoamine oxidase inhibitors have similar efficacy in the treatment of depression and panic disorder, potent blockade of 5-ht transport appears to be a prerequisite for effective treatment of ocd. |
1993-10-20 |
2023-08-12 |
Not clear |
| T A Weh. Seasonal vulnerability to depression. Implications for etiology and treatment. L'Encephale. vol 18 Spec No 4. 1993-10-19. PMID:1308842. |
although no single system has been shown to be responsible for the syndrome, there is evidence that the indole hormone melatonin, the indole neurotransmitter serotonin, and the peptide neurohormone corticotropin releasing hormone (crh) play roles in the pathophysiology and phototherapy of winter depression. |
1993-10-19 |
2023-08-11 |
Not clear |
| V Glover, J Jarman, M Sandle. Migraine and depression: biological aspects. Journal of psychiatric research. vol 27. issue 2. 1993-10-05. PMID:8366471. |
there is a considerable overlap in migraine and depression incidence, and both conditions may be associated with low levels of 5-hydroxytryptamine (5-ht). |
1993-10-05 |
2023-08-12 |
Not clear |
| D I Wallis, J W. The pharmacology of descending responses evoked by thoracic stimulation in the neonatal rat spinal cord in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 347. issue 6. 1993-09-28. PMID:8103194. |
potentiation of certain responses by the 5-ht2 antagonists, ketanserin, ritanserin and lilly 53837, indicated that endogenous 5-ht was exerting a modulatory depression of these responses. |
1993-09-28 |
2023-08-12 |
rat |
| G Biagini, E M Pich, C Carani, P Marrama, J A Gustafsson, K Fuxe, L F Agnat. Indole-pyruvic acid, a tryptophan ketoanalogue, antagonizes the endocrine but not the behavioral effects of repeated stress in a model of depression. Biological psychiatry. vol 33. issue 10. 1993-09-22. PMID:8353166. |
we investigated the effects of a serotonin precursor, indole-pyruvic acid (ipa), in an animal model of depression based on repeated exposure to unpredictable stress. |
1993-09-22 |
2023-08-12 |
rat |
| D W Brow. Abnormal fluctuations of acetylcholine and serotonin. Medical hypotheses. vol 40. issue 5. 1993-09-14. PMID:8350780. |
this communication cites evidence which suggests that fluctuations of serotonin might have a causative role in migraine, mania, and depression and that fluctuations of acetylcholine might have a causative role in epilepsy, catalepsy, and kleine-levin attacks. |
1993-09-14 |
2023-08-12 |
Not clear |
| P G Kostyuk, E A Lukyanet. Mechanisms of antagonistic action of internal Ca2+ on serotonin-induced potentiation of Ca2+ currents in Helix neurones. Pflugers Archiv : European journal of physiology. vol 424. issue 1. 1993-09-10. PMID:7688896. |
leupeptin (100 microm), a blocker of ca(2+)-dependent proteases did not influence the amplitude of 5-ht effect, indicating that channel proteolysis is not involved in the depression. |
1993-09-10 |
2023-08-12 |
Not clear |
| R Auste. Sertraline: a new antidepressant. American family physician. vol 48. issue 2. 1993-09-02. PMID:8342482. |
sertraline is a serotonin reuptake inhibitor that has been approved for use in the treatment of depression. |
1993-09-02 |
2023-08-12 |
Not clear |
| R T Joffe, D R Schulle. An open study of buspirone augmentation of serotonin reuptake inhibitors in refractory depression. The Journal of clinical psychiatry. vol 54. issue 7. 1993-08-26. PMID:8335654. |
an open study of buspirone augmentation of serotonin reuptake inhibitors in refractory depression. |
1993-08-26 |
2023-08-12 |
Not clear |
| S M Holliday, G L Ploske. Paroxetine. A review of its pharmacology, therapeutic use in depression and therapeutic potential in diabetic neuropathy. Drugs & aging. vol 3. issue 3. 1993-08-12. PMID:8324301. |
paroxetine is a selective serotonin reuptake inhibitor effective in a once-daily administration regimen in the treatment of depression. |
1993-08-12 |
2023-08-12 |
Not clear |
| S M Holliday, G L Ploske. Paroxetine. A review of its pharmacology, therapeutic use in depression and therapeutic potential in diabetic neuropathy. Drugs & aging. vol 3. issue 3. 1993-08-12. PMID:8324301. |
future research should attempt to define more fully the efficacy of paroxetine as long term prophylactic therapy for recurrent depression and to assess how its overall therapeutic profile compares with other selective serotonin reuptake inhibitors in the elderly. |
1993-08-12 |
2023-08-12 |
Not clear |
| P Yavari, G W Vogel, D B Neil. Decreased raphe unit activity in a rat model of endogenous depression. Brain research. vol 611. issue 1. 1993-07-29. PMID:8390911. |
one theory about the pathogenesis of endogenous depression is that decreased serotonergic (5-ht) neurotransmission is involved in producing the disorder. |
1993-07-29 |
2023-08-12 |
human |
| P Yavari, G W Vogel, D B Neil. Decreased raphe unit activity in a rat model of endogenous depression. Brain research. vol 611. issue 1. 1993-07-29. PMID:8390911. |
we tested the hypothesis that the discharge rate of 5-ht neurons in the drn was decreased in a new animal (rat) model of human endogenous depression. |
1993-07-29 |
2023-08-12 |
human |
| P Yavari, G W Vogel, D B Neil. Decreased raphe unit activity in a rat model of endogenous depression. Brain research. vol 611. issue 1. 1993-07-29. PMID:8390911. |
this correlation is consistent with the theory that 5-ht neurotransmission is diminished in endogenous depression. |
1993-07-29 |
2023-08-12 |
human |
| P E Stoke. Fluoxetine: a five-year review. Clinical therapeutics. vol 15. issue 2. 1993-07-26. PMID:8519034. |
the introduction in 1988 of fluoxetine hydrochloride, the first selective serotonin uptake inhibitor (ssui) or selective serotonin reuptake inhibitor (ssri) available in the united states, represented a major advance in the pharmacologic management of depression. |
1993-07-26 |
2023-08-12 |
Not clear |