| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Apter, G Ratzoni, R A King, A Weizman, I Iancu, M Binder, M A Riddl. Fluvoxamine open-label treatment of adolescent inpatients with obsessive-compulsive disorder or depression. Journal of the American Academy of Child and Adolescent Psychiatry. vol 33. issue 3. 1994-06-02. PMID:8169178. |
fluvoxamine, a monocyclic, specific serotonin uptake inhibitor with demonstrated efficacy in obsessive-compulsive disorder (ocd) and depression in adults, is marketed in more than 30 countries worldwide, including israel. |
1994-06-02 |
2023-08-12 |
Not clear |
| H Agren, L Reibrin. PET studies of presynaptic monoamine metabolism in depressed patients and healthy volunteers. Pharmacopsychiatry. vol 27. issue 1. 1994-05-19. PMID:8159778. |
the availability of 11c-labelled 5-hydroxytryptophan (5-htp) and l-dopa, the direct precursors in the synthetic pathways to serotonin and dopamine, has allowed positron emission tomographic (pet) studies in 8 healthy volunteers and 6 patients suffering from unipolar depression. |
1994-05-19 |
2023-08-12 |
human |
| J Demlin. [Fear, violence and depression--does too little serotonin make the mind ill?]. Fortschritte der Medizin. vol 112. issue 4. 1994-05-12. PMID:8150402. |
[fear, violence and depression--does too little serotonin make the mind ill? |
1994-05-12 |
2023-08-12 |
Not clear |
| P Toren, A Weizma. Is serotonin the main culprit in depression? Israel journal of medical sciences. vol 30. issue 2. 1994-05-10. PMID:8150604. |
is serotonin the main culprit in depression? |
1994-05-10 |
2023-08-12 |
Not clear |
| F S Guimarães, E A Del Bel, C M Padovan, S M Netto, R T de Almeid. Hippocampal 5-HT receptors and consolidation of stressful memories. Behavioural brain research. vol 58. issue 1-2. 1994-04-25. PMID:8136041. |
it has been suggested that postsynaptic 5-ht1a receptors in the hippocampus, innervated by 5-ht neurons localized in the median raphe nucleus, mediate adaptive or coping responses to aversive events and that dysfunction of this system is related to symptoms of depression. |
1994-04-25 |
2023-08-12 |
rat |
| V Manna, F Bolino, L Di Cicc. Chronic tension-type headache, mood depression and serotonin: therapeutic effects of fluvoxamine and mianserine. Headache. vol 34. issue 1. 1994-04-15. PMID:8132440. |
chronic tension-type headache, mood depression and serotonin: therapeutic effects of fluvoxamine and mianserine. |
1994-04-15 |
2023-08-12 |
human |
| J Ortiz, C Mariscot, E Alvarez, F Artiga. Effects of the antidepressant drug tianeptine on plasma and platelet serotonin of depressive patients and healthy controls. Journal of affective disorders. vol 29. issue 4. 1994-04-08. PMID:7510316. |
however, long-term treatment tended (p < 0.06) to increase basal plasma 5-ht concentrations, in covariation with decreases of madrs (montgomery-asberg depression rating scale) and hars (hamilton anxiety rating scale). |
1994-04-08 |
2023-08-12 |
Not clear |
| P L Delgado, H L Miller, R M Salomon, J Licinio, G R Heninger, A J Gelenberg, D S Charne. Monoamines and the mechanism of antidepressant action: effects of catecholamine depletion on mood of patients treated with antidepressants. Psychopharmacology bulletin. vol 29. issue 3. 1994-04-07. PMID:8121966. |
the 3 desipramine- and 2 mazindol-responders had a rapid increase in depression score during ampt but not placebo (diphenhydramine) challenge whereas only 1 of 9 selective serotonin reuptake inhibitor (ssri)-treated patients did. |
1994-04-07 |
2023-08-12 |
Not clear |
| E H Jaffe, V De Frias, C Ibarr. Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression. Neuroscience letters. vol 162. issue 1-2. 1994-04-04. PMID:8121620. |
changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression. |
1994-04-04 |
2023-08-12 |
rat |
| E H Jaffe, V De Frias, C Ibarr. Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression. Neuroscience letters. vol 162. issue 1-2. 1994-04-04. PMID:8121620. |
this constitutes the first direct demonstration of a decreased tonic release of serotonin from different nuclei during depression. |
1994-04-04 |
2023-08-12 |
rat |
| J Akiyoshi, K Tsuchiyama, Y Mizobe, M Nakamura, H Kuranaga, H Nagayam. Effects of chronic mianserin administration on serotonin metabolism and receptors in the 5-hydroxytryptophan depression model. Progress in neuro-psychopharmacology & biological psychiatry. vol 18. issue 1. 1994-03-31. PMID:7509496. |
effects of chronic mianserin administration on serotonin metabolism and receptors in the 5-hydroxytryptophan depression model. |
1994-03-31 |
2023-08-12 |
Not clear |
| M J Owens, C B Nemerof. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clinical chemistry. vol 40. issue 2. 1994-03-24. PMID:7508830. |
role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. |
1994-03-24 |
2023-08-12 |
Not clear |
| M J Owens, C B Nemerof. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clinical chemistry. vol 40. issue 2. 1994-03-24. PMID:7508830. |
in our studies, this reduction in platelet 5-ht transporter binding is not due to prior antidepressant treatment of hypercortisolemia and is not observed in mania, alzheimer disease, schizophrenia, panic disorder, fibromyalgia, or atypical depression. |
1994-03-24 |
2023-08-12 |
Not clear |
| M J Owens, C B Nemerof. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clinical chemistry. vol 40. issue 2. 1994-03-24. PMID:7508830. |
these findings support the hypothesis that alterations in 5-ht neurons play a role in the pathophysiology of depression. |
1994-03-24 |
2023-08-12 |
Not clear |
| C B Nemerof. Paroxetine: an overview of the efficacy and safety of a new selective serotonin reuptake inhibitor in the treatment of depression. Journal of clinical psychopharmacology. vol 13. issue 6 Suppl 2. 1994-03-23. PMID:8106649. |
paroxetine: an overview of the efficacy and safety of a new selective serotonin reuptake inhibitor in the treatment of depression. |
1994-03-23 |
2023-08-12 |
Not clear |
| J G Csernansky, Y I Shelin. Abnormalities of serotonin metabolism and nonpsychotic psychiatric disorders. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 5. issue 4. 1994-03-23. PMID:8312985. |
abnormalities of brain serotonin (5-hydroxytryptamine; 5-ht) metabolism have been proposed as the neurobiological basis of a vulnerability to depression and of a long-standing tendency toward impulsivity and aggression. |
1994-03-23 |
2023-08-12 |
Not clear |
| W A Nolen, E Hoencamp, P F Bouvy, P M Haffman. Reversible monoamine oxidase-A inhibitors in resistant major depression. Clinical neuropharmacology. vol 16 Suppl 2. 1994-03-23. PMID:8313400. |
monoamine oxidase (mao) inhibitors (maois) provide effective alternative therapy for those patients with major depression who do not respond to tricyclic antidepressants or such related compounds as the selective serotonin reuptake inhibitors. |
1994-03-23 |
2023-08-12 |
Not clear |
| S N Youn. The use of diet and dietary components in the study of factors controlling affect in humans: a review. Journal of psychiatry & neuroscience : JPN. vol 18. issue 5. 1994-03-09. PMID:8297922. |
these data indicate that low serotonin levels alone cannot cause depression. |
1994-03-09 |
2023-08-12 |
human |
| S N Youn. The use of diet and dietary components in the study of factors controlling affect in humans: a review. Journal of psychiatry & neuroscience : JPN. vol 18. issue 5. 1994-03-09. PMID:8297922. |
however, serotonin does have a direct effect on mood, and low levels of serotonin contribute to the etiology of depression in some depressed patients. |
1994-03-09 |
2023-08-12 |
human |
| J J Wurtma. Depression and weight gain: the serotonin connection. Journal of affective disorders. vol 29. issue 2-3. 1994-03-08. PMID:8300977. |
depression and weight gain: the serotonin connection. |
1994-03-08 |
2023-08-12 |
Not clear |