| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Owens, C B Nemerof. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clinical chemistry. vol 40. issue 2. 1994-03-24. PMID:7508830. |
these findings support the hypothesis that alterations in 5-ht neurons play a role in the pathophysiology of depression. |
1994-03-24 |
2023-08-12 |
Not clear |
| C B Nemerof. Paroxetine: an overview of the efficacy and safety of a new selective serotonin reuptake inhibitor in the treatment of depression. Journal of clinical psychopharmacology. vol 13. issue 6 Suppl 2. 1994-03-23. PMID:8106649. |
paroxetine: an overview of the efficacy and safety of a new selective serotonin reuptake inhibitor in the treatment of depression. |
1994-03-23 |
2023-08-12 |
Not clear |
| J G Csernansky, Y I Shelin. Abnormalities of serotonin metabolism and nonpsychotic psychiatric disorders. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 5. issue 4. 1994-03-23. PMID:8312985. |
abnormalities of brain serotonin (5-hydroxytryptamine; 5-ht) metabolism have been proposed as the neurobiological basis of a vulnerability to depression and of a long-standing tendency toward impulsivity and aggression. |
1994-03-23 |
2023-08-12 |
Not clear |
| W A Nolen, E Hoencamp, P F Bouvy, P M Haffman. Reversible monoamine oxidase-A inhibitors in resistant major depression. Clinical neuropharmacology. vol 16 Suppl 2. 1994-03-23. PMID:8313400. |
monoamine oxidase (mao) inhibitors (maois) provide effective alternative therapy for those patients with major depression who do not respond to tricyclic antidepressants or such related compounds as the selective serotonin reuptake inhibitors. |
1994-03-23 |
2023-08-12 |
Not clear |
| S N Youn. The use of diet and dietary components in the study of factors controlling affect in humans: a review. Journal of psychiatry & neuroscience : JPN. vol 18. issue 5. 1994-03-09. PMID:8297922. |
these data indicate that low serotonin levels alone cannot cause depression. |
1994-03-09 |
2023-08-12 |
human |
| S N Youn. The use of diet and dietary components in the study of factors controlling affect in humans: a review. Journal of psychiatry & neuroscience : JPN. vol 18. issue 5. 1994-03-09. PMID:8297922. |
however, serotonin does have a direct effect on mood, and low levels of serotonin contribute to the etiology of depression in some depressed patients. |
1994-03-09 |
2023-08-12 |
human |
| J J Wurtma. Depression and weight gain: the serotonin connection. Journal of affective disorders. vol 29. issue 2-3. 1994-03-08. PMID:8300977. |
depression and weight gain: the serotonin connection. |
1994-03-08 |
2023-08-12 |
Not clear |
| J R Cornelius, I M Salloum, M D Cornelius, J M Perel, M E Thase, J G Ehler, J J Man. Fluoxetine trial in suicidal depressed alcoholics. Psychopharmacology bulletin. vol 29. issue 2. 1994-02-23. PMID:8290665. |
however, no trials with any selective serotonin agonist have been reported in patients who display both major depression and alcoholism. |
1994-02-23 |
2023-08-12 |
Not clear |
| V Aubin-Brune. [A scale for clinical evaluation of serotonergic deficit in elderly people]. L'Encephale. vol 19 Spec No 2. 1994-02-17. PMID:8281907. |
the factorial structure does not depend on the psychiatric diagnosis: the 5-ht scale is not correlated with the covi anxiety scale, the jouvent mood scale, the widlocher slowing down scale or the hamilton depression scale in the subgroup of depressed subjects. |
1994-02-17 |
2023-08-12 |
human |
| V Aubin-Brune. [A scale for clinical evaluation of serotonergic deficit in elderly people]. L'Encephale. vol 19 Spec No 2. 1994-02-17. PMID:8281907. |
factorial analysis on the cumulated items of the 5-ht and hamilton depression scales shows dispersion of the items on the latter scale whereas those on the 5-ht retain a factorial distribution. |
1994-02-17 |
2023-08-12 |
human |
| T G Dina. A rational approach to the non-responding depressed patient. International clinical psychopharmacology. vol 8. issue 4. 1994-02-04. PMID:8277139. |
lithium augmentation of traditional tricyclic antidepressants and selective serotonin re-uptake inhibitors such as fluoxetine are the most extensively investigated combinations used to treat non-responsive depression. |
1994-02-04 |
2023-08-12 |
Not clear |
| T L Sherman, C J McDougle, L H Pric. Paroxetine: a new serotonin reuptake inhibitor for the treatment of depression. Connecticut medicine. vol 57. issue 9. 1994-01-13. PMID:8252846. |
paroxetine: a new serotonin reuptake inhibitor for the treatment of depression. |
1994-01-13 |
2023-08-12 |
Not clear |
| T L Sherman, C J McDougle, L H Pric. Paroxetine: a new serotonin reuptake inhibitor for the treatment of depression. Connecticut medicine. vol 57. issue 9. 1994-01-13. PMID:8252846. |
the introduction of the selective serotonin reuptake inhibitors (ssris) over the past several years has made a major impact on the treatment of depression and other neuropsychiatric disorders. |
1994-01-13 |
2023-08-12 |
Not clear |
| A Haider, D R Miller, R D Stato. Use of serotonergic drugs for treating depression in older patients. Geriatrics. vol 48. issue 12. 1994-01-13. PMID:8253394. |
the selective serotonin reuptake inhibitors (ssris) offer a relatively new alternative to traditional tricyclic antidepressants (tcas) in the treatment of depression in older adults. |
1994-01-13 |
2023-08-12 |
Not clear |
| C E Sortwell, J Sage. Induction of antidepressive activity by monoaminergic transplants in rat neocortex. Pharmacology, biochemistry, and behavior. vol 46. issue 1. 1994-01-10. PMID:8255915. |
these results support an important role for neocortical 5-ht and ne transmission in antidepressant activity and suggest that transplants of monoaminergic-containing tissue can reduce biochemical deficits in depression. |
1994-01-10 |
2023-08-12 |
rat |
| P Bec. Acute therapy of depression. The Journal of clinical psychiatry. vol 54 Suppl. 1994-01-07. PMID:8253702. |
the acute therapy (the initial 8 weeks of treatment) of depression (including the whole spectrum of "less than major," "major," and "more than major") has been reviewed comparing the old tricyclics with the new generations (especially mianserin, moclobemide, and the serotonin selective reuptake inhibitors (ssris), i.e., citalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline). |
1994-01-07 |
2023-08-12 |
Not clear |
| E I Solntsev. [The role of cAMP in the electrophysiological effects of morphine and enkephalins]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 43. issue 5. 1994-01-06. PMID:8249468. |
these effects are: a membrane hyperpolarization, a depression of the bursting activity, an inhibition of the excitatory serotonin and dopamine responses. |
1994-01-06 |
2023-08-12 |
Not clear |
| R F Cox, E Meller, B L Waszcza. Electrophysiological evidence for a large receptor reserve for inhibition of dorsal raphe neuronal firing by 5-HT1A agonists. Synapse (New York, N.Y.). vol 14. issue 4. 1994-01-03. PMID:8248853. |
however, unlike effects on serotonin synthesis, eedq treatments caused no depression of the maximal inhibitory response for any of the agonists, although all dose-response curves were shifted to the right (ed50's: 10.1 micrograms/kg, 6.7-fold shift, 8-oh-dpat; 139.9 micrograms/kg, 4.7-fold shift, ipsapirone; 53.8 micrograms/kg, 3.1-fold shift, bmy 7378). |
1994-01-03 |
2023-08-12 |
rat |
| R Leira, J Castillo, F Martinez, J M Prieto, M Noy. Platelet-rich plasma serotonin levels in tension-type headache and depression. Cephalalgia : an international journal of headache. vol 13. issue 5. 1993-12-30. PMID:8242728. |
platelet-rich plasma serotonin levels in tension-type headache and depression. |
1993-12-30 |
2023-08-12 |
Not clear |
| R Leira, J Castillo, F Martinez, J M Prieto, M Noy. Platelet-rich plasma serotonin levels in tension-type headache and depression. Cephalalgia : an international journal of headache. vol 13. issue 5. 1993-12-30. PMID:8242728. |
we measured platelet-rich plasma (prp) serotonin in patients suffering from tension-type headache, before and after treatment with amitriptyline, comparing them with a healthy control group and patients with untreated depression. |
1993-12-30 |
2023-08-12 |
Not clear |