| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G G Kinney, G W Vogel, P Fen. Decreased dorsal raphe nucleus neuronal activity in adult chloral hydrate anesthetized rats following neonatal clomipramine treatment: implications for endogenous depression. Brain research. vol 756. issue 1-2. 1997-08-15. PMID:9187315. |
although the biological cause of endogenous depression is unknown, one commonly held hypothesis proposes that depression results, in part, from decreased central serotonin (5-ht) neurotransmission. |
1997-08-15 |
2023-08-12 |
human |
| G G Kinney, G W Vogel, P Fen. Decreased dorsal raphe nucleus neuronal activity in adult chloral hydrate anesthetized rats following neonatal clomipramine treatment: implications for endogenous depression. Brain research. vol 756. issue 1-2. 1997-08-15. PMID:9187315. |
the results thereby lend support to the hypothesis of a role for decreased central 5-ht as a substrate for the behavioral deficiencies observed in endogenous depression and suggest that these deficiencies may also result, in part, from a random, rather than orderly, temporal pattern of discharge in these neurons. |
1997-08-15 |
2023-08-12 |
human |
| E Schulz, C Fleischhaker, H E Remschmid. Correlated changes in symptoms and neurotransmitter indices during maintenance treatment with clozapine or conventional neuroleptics in adolescents and young adults with schizophrenia. Journal of child and adolescent psychopharmacology. vol 6. issue 2. 1997-08-15. PMID:9231304. |
higher serotonin levels were associated with significantly fewer negative symptoms, whereas higher mhpg levels were correlated with less depression. |
1997-08-15 |
2023-08-12 |
Not clear |
| E Schulz, C Fleischhaker, H E Remschmid. Correlated changes in symptoms and neurotransmitter indices during maintenance treatment with clozapine or conventional neuroleptics in adolescents and young adults with schizophrenia. Journal of child and adolescent psychopharmacology. vol 6. issue 2. 1997-08-15. PMID:9231304. |
these findings suggest involvement of norepinephrine and serotonin in the pathophysiology of schizophrenia (with depression associated with lower mhpg levels and negative symptoms associated with lower serotonin levels) and in the therapeutic actions of clozapine. |
1997-08-15 |
2023-08-12 |
Not clear |
| R L Findlin. Open-label treatment of comorbid depression and attentional disorders with co-administration of serotonin reuptake inhibitors and psychostimulants in children, adolescents, and adults: a case series. Journal of child and adolescent psychopharmacology. vol 6. issue 3. 1997-08-15. PMID:9231310. |
open-label treatment of comorbid depression and attentional disorders with co-administration of serotonin reuptake inhibitors and psychostimulants in children, adolescents, and adults: a case series. |
1997-08-15 |
2023-08-12 |
Not clear |
| P Hertel, G G Nomikos, B Schilström, L Arborelius, T H Svensso. Risperidone dose-dependently increases extracellular concentrations of serotonin in the rat frontal cortex: role of alpha 2-adrenoceptor antagonism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 17. issue 1. 1997-08-13. PMID:9194049. |
the enhanced 5-ht output in the fc by risperidone may be of particular relevance for the treatment of schizophrenia when associated with depression and in schizoaffective disorder. |
1997-08-13 |
2023-08-12 |
rat |
| W J Burke, V Dewan, S P Wengel, W H Roccaforte, G C Nadolny, D G Folk. The use of selective serotonin reuptake inhibitors for depression and psychosis complicating dementia. International journal of geriatric psychiatry. vol 12. issue 5. 1997-08-08. PMID:9193959. |
the use of selective serotonin reuptake inhibitors for depression and psychosis complicating dementia. |
1997-08-08 |
2023-08-12 |
Not clear |
| W J Burke, V Dewan, S P Wengel, W H Roccaforte, G C Nadolny, D G Folk. The use of selective serotonin reuptake inhibitors for depression and psychosis complicating dementia. International journal of geriatric psychiatry. vol 12. issue 5. 1997-08-08. PMID:9193959. |
this retrospective chart review examines the impact of selective serotonin reuptake inhibitors on 20 patients with both depression and psychosis complicating dementia of the alzheimer type (dat) and other dementias. |
1997-08-08 |
2023-08-12 |
Not clear |
| W J Burke, V Dewan, S P Wengel, W H Roccaforte, G C Nadolny, D G Folk. The use of selective serotonin reuptake inhibitors for depression and psychosis complicating dementia. International journal of geriatric psychiatry. vol 12. issue 5. 1997-08-08. PMID:9193959. |
the selective serotonin reuptake inhibitors may have an important role to play in patients with dat who have coexisting depression and psychosis. |
1997-08-08 |
2023-08-12 |
Not clear |
| D Nut. Management of patients with depression associated with anxiety symptoms. The Journal of clinical psychiatry. vol 58 Suppl 8. 1997-08-07. PMID:9236730. |
treatment options for depression with anxiety include tricyclic antidepressants (tcas) and serotonin selective reuptake inhibitors (ssris). |
1997-08-07 |
2023-08-12 |
Not clear |
| A González-Pinto, J J López-Ibor, J Sáiz, M Gutiérrez, J L Figuerido, E Elizagárate, J L Pérez de Heredi. [Serotonergic function in endogeneity of depression]. Actas luso-espanolas de neurologia, psiquiatria y ciencias afines. vol 25. issue 2. 1997-08-06. PMID:9245192. |
the neuroendocrine responses to acute intravenous administration of the serotonin (5-ht) reuptake inhibitor clomipramine were assessed in patients with major depression with melancholia (dmm) and matched subjects with major depression (dm) (without melancholia) and dysthimic disorder (td). |
1997-08-06 |
2023-08-12 |
human |
| J L Yau, J Noble, J R Seck. Site-specific regulation of corticosteroid and serotonin receptor subtype gene expression in the rat hippocampus following 3,4-methylenedioxymethamphetamine: role of corticosterone and serotonin. Neuroscience. vol 78. issue 1. 1997-08-01. PMID:9135093. |
abnormal interactions between serotonin (5-hydroxytryptamine) and glucocorticoids, notably in the hippocampus, may underpin neuroendocrine, affective and cognitive dysfunction in depression and ageing. |
1997-08-01 |
2023-08-12 |
rat |
| T J Taiminen, E Syvälahti, S Saarijärvi, H Niemi, H Lehto, V Ahola, R K Salokanga. Citalopram as an adjuvant in schizophrenia: further evidence for a serotonergic dimension in schizophrenia. International clinical psychopharmacology. vol 12. issue 1. 1997-07-31. PMID:9179631. |
the effect of the adjuvant selective serotonin reuptake inhibitor citalopram was assessed regarding the symptom dimensions of schizophrenia measured with the positive and negative syndrome scale (panss) and with the hamilton rating scale for depression (hrsd). |
1997-07-31 |
2023-08-12 |
Not clear |
| R L Coulson, M Klei. Rapid development of synaptic connections and plasticity between sensory neurons and motor neurons of Aplysia in cell culture: implications for learning and regulation of synaptic strength. Journal of neurophysiology. vol 77. issue 5. 1997-07-30. PMID:9163360. |
we find that synaptic responses can be elicited in 50% of sensory neuron-motor neuron pairs by 1 h after cell contact and that short-term homosynaptic depression and synaptic augmentation and restoration by the endogenous facilitatory transmitter serotonin are present at the earliest stages of synapse formation. |
1997-07-30 |
2023-08-12 |
aplysia |
| D Ball, L Hill, B Freeman, T C Eley, J Strelau, R Riemann, F M Spinath, A Angleitner, R Plomi. The serotonin transporter gene and peer-rated neuroticism. Neuroreport. vol 8. issue 5. 1997-07-30. PMID:9175133. |
polymorphisms in the serotonin transporter gene (5htt) have been reported to be associated with neuroticism (emotionality) and with depression. |
1997-07-30 |
2023-08-12 |
Not clear |
| M Jakovljević, D Mück-Seler, N Pivac, D Ljubicić, M Bujas, G Dodi. Seasonal influence on platelet 5-HT levels in patients with recurrent major depression and schizophrenia. Biological psychiatry. vol 41. issue 10. 1997-07-29. PMID:9129783. |
seasonal influence on platelet 5-ht levels in patients with recurrent major depression and schizophrenia. |
1997-07-29 |
2023-08-12 |
Not clear |
| O Benkert, A Szegedi, H Wetzel, H J Staab, W Meister, M Philip. Dose escalation vs. continued doses of paroxetine and maprotiline: a prospective study in depressed out-patients with inadequate treatment response. Acta psychiatrica Scandinavica. vol 95. issue 4. 1997-07-29. PMID:9150822. |
in view of the fact that controlled prospective studies on the benefits of dose escalation of the selective serotonin re-uptake inhibitor (ssri) paroxetine are lacking, we conducted a double-blind, randomized, parallel-group multicentre study designed to compare the possible benefits of dose escalation of paroxetine and maprotiline in patients suffering from major or minor depression according to modified research diagnostic criteria (rdc) with inadequate treatment response. |
1997-07-29 |
2023-08-12 |
Not clear |
| M Berk, K Kessa, C P Szabo, N Butko. The augmented platelet intracellular calcium response to serotonin in anorexia nervosa but not bulimia may be due to subsyndromal depression. The International journal of eating disorders. vol 22. issue 1. 1997-07-22. PMID:9140736. |
the augmented platelet intracellular calcium response to serotonin in anorexia nervosa but not bulimia may be due to subsyndromal depression. |
1997-07-22 |
2023-08-12 |
Not clear |
| Y I Sheline, K E Freedland, R M Carne. How safe are serotonin reuptake inhibitors for depression in patients with coronary heart disease? The American journal of medicine. vol 102. issue 1. 1997-07-17. PMID:9209201. |
how safe are serotonin reuptake inhibitors for depression in patients with coronary heart disease? |
1997-07-17 |
2023-08-12 |
Not clear |
| J L Elmore, J T Quattlebau. Female sexual stimulation during antidepressant treatment. Pharmacotherapy. vol 17. issue 3. 1997-07-15. PMID:9165567. |
three women with several diagnoses, including depression and psychosis, personality disorder, attention deficit hyperactivity disorder, alcohol abuse, and physical disease, were treated with selective serotonin reuptake inhibitors (fluoxetine, paroxetine, fluvoxamine). |
1997-07-15 |
2023-08-12 |
Not clear |