| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Meyer, S Kennedy, G M Brow. No effect of depression on [(15)O]H2O PET response to intravenous d-fenfluramine. The American journal of psychiatry. vol 155. issue 9. 1998-09-16. PMID:9734549. |
in this study abnormalities in regional neuromodulation by serotonin in major depression were assessed with intravenous d-fenfluramine and [(15)o]h2o pet. |
1998-09-16 |
2023-08-12 |
human |
| E Seifritz, J C Gillin, M H Rapaport, J R Kelsoe, T Bhatti, S M Stah. Sleep electroencephalographic response to muscarinic and serotonin1A receptor probes in patients with major depression and in normal controls. Biological psychiatry. vol 44. issue 1. 1998-09-02. PMID:9646880. |
to test the hypothesis that depression is associated with an increased ratio of cholinergic to serotonergic neurotransmission, we compared the effects of pilocarpine, a muscarinic agonist, and ipsapirone, a serotonin (5-ht)1a agonist, on electroencephalographic (eeg) sleep in depressed and healthy subjects. |
1998-09-02 |
2023-08-12 |
human |
| R H McAllister-Williams, I N Ferrier, A H Youn. Mood and neuropsychological function in depression: the role of corticosteroids and serotonin. Psychological medicine. vol 28. issue 3. 1998-08-31. PMID:9626714. |
mood and neuropsychological function in depression: the role of corticosteroids and serotonin. |
1998-08-31 |
2023-08-12 |
Not clear |
| C Wang, R S Zucke. Regulation of synaptic vesicle recycling by calcium and serotonin. Neuron. vol 21. issue 1. 1998-08-31. PMID:9697860. |
by analysis of synaptic depression using a depletion model and measurement of vesicle recycling using the styryl dye fm1-43, we show that serotonin increases the number of vesicles available for transmitter release (total synaptic vesicle pool size). |
1998-08-31 |
2023-08-12 |
Not clear |
| M S Clark, A F Russ. Measurement of tryptophan hydroxylase mRNA levels by competitive RT-PCR. Brain research. Brain research protocols. vol 2. issue 4. 1998-08-27. PMID:9630672. |
numeroff, role of serotonin in the pathophysiology of depression: focus on the serotonin transporter, clin. |
1998-08-27 |
2023-08-12 |
rat |
| R V Varner, P Ruiz, D R Smal. Black and white patients response to antidepressant treatment for major depression. The Psychiatric quarterly. vol 69. issue 2. 1998-08-12. PMID:9627929. |
likewise, we also advance that black patients might need lower doses of selective serotonin re-uptake inhibitor antidepressants (ssris) than white patients to attain a similar response in the treatment of major depression. |
1998-08-12 |
2023-08-12 |
Not clear |
| P A Broderick, O Hope, P Jeanno. Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in vivo CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal. Progress in neuro-psychopharmacology & biological psychiatry. vol 22. issue 2. 1998-08-11. PMID:9608607. |
mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in vivo ca1 hippocampal norepinephrine and serotonin release detection in the behaving animal. |
1998-08-11 |
2023-08-12 |
rat |
| K Yoshida, H Higuchi, M Kamata, M Yoshimoto, T Shimizu, Y Hishikaw. Single and repeated electroconvulsive shocks activate dopaminergic and 5-hydroxytryptaminergic neurotransmission in the frontal cortex of rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 22. issue 2. 1998-08-11. PMID:9608612. |
these results suggest that the activating effect of repeated ect on 5-hydroxytryptaminergic (5-ht) and da neurotransmission, (especially on 5-ht neurotransmission), is significant in improving depression both in patients with parkinson's disease (pd) and in those who do not suffer from pd. |
1998-08-11 |
2023-08-12 |
rat |
| P Sandor, B Baker, J Irvine, P Dorian, D McKessok, S Mendlowit. Effectiveness of fluoxetine and doxepin in treatment of melancholia in depressed patients. Depression and anxiety. vol 7. issue 2. 1998-08-04. PMID:9614594. |
it has been suggested that serotonin reuptake inhibitors (ssris) may be less effective than tricyclic antidepressants (tcas) in treatment of melancholic depression. |
1998-08-04 |
2023-08-12 |
Not clear |
| K Beliles, A Stoudemir. Psychopharmacologic treatment of depression in the medically ill. Psychosomatics. vol 39. issue 3. 1998-08-04. PMID:9664784. |
while in the past antidepressant drug selection was limited by the almost sole availability of the tricyclic antidepressants, newer drugs such as selective serotonin reuptake inhibitors, bupropion, and venlafaxine have vastly simplified treating depression in the medically ill. |
1998-08-04 |
2023-08-12 |
Not clear |
| F R Sallee, R Hilal, D Dougherty, K Beach, L Nesbit. Platelet serotonin transporter in depressed children and adolescents: 3H-paroxetine platelet binding before and after sertraline. Journal of the American Academy of Child and Adolescent Psychiatry. vol 37. issue 7. 1998-07-29. PMID:9666634. |
to evaluate serotonin transporter protein (5htpr) binding in platelets from children and adolescents with major depression (mdd) compared to normal controls using the selective ligand 3h-paroxetine. |
1998-07-29 |
2023-08-12 |
Not clear |
| M Horni. Addressing comorbidity in adults with attention-deficit/hyperactivity disorder. The Journal of clinical psychiatry. vol 59 Suppl 7. 1998-07-29. PMID:9680055. |
serotonin and norepinephrine are implicated in major depression and anxiety disorders, while self-medication for dopamine dysfunction may relate to substance abuse. |
1998-07-29 |
2023-08-12 |
Not clear |
| Reports from the Canadian Coordinating Office for Health Technology Assessment (CCOHTA). Selective serotonin reuptake inhibitors for major depression. International journal of technology assessment in health care. vol 14. issue 2. 1998-07-17. PMID:9611913. |
selective serotonin reuptake inhibitors for major depression. |
1998-07-17 |
2023-08-12 |
Not clear |
| N E Rosenthal, C M Mazzanti, R L Barnett, T A Hardin, E H Turner, G K Lam, N Ozaki, D Goldma. Role of serotonin transporter promoter repeat length polymorphism (5-HTTLPR) in seasonality and seasonal affective disorder. Molecular psychiatry. vol 3. issue 2. 1998-07-16. PMID:9577843. |
the short (s), as opposed to the long (l), allele of the 5-ht transporter linked polymorphism (5-httlpr) has been associated with neuroticism and depression. |
1998-07-16 |
2023-08-12 |
Not clear |
| C Houc. An open-label pilot study of fluvoxamine for mixed anxiety-depression. Psychopharmacology bulletin. vol 34. issue 2. 1998-07-14. PMID:9641005. |
fluvoxamine, a selective serotonin reuptake inhibitor (ssri) approved for the treatment of obsessive-compulsive disorder, was studied for its effectiveness in treating anxiety and depression simultaneously during an 8-week, open-label trial of patients with mad. |
1998-07-14 |
2023-08-12 |
Not clear |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
neurobiology of serotonin in depression and suicide. |
1998-06-24 |
2023-08-12 |
human |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
alterations in serotonin neurotransmission have been implicated in the pathophysiology of major depression and suicide. |
1998-06-24 |
2023-08-12 |
human |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
altered signal transduction in cerebral cortex and altered regulation of serotonin neurons in the dr may be important in the pathophysiology of major depression and suicide. |
1998-06-24 |
2023-08-12 |
human |
| J Fawcett, K A Busch, D Jacobs, H M Kravitz, L Fog. Suicide: a four-pathway clinical-biochemical model. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616805. |
this chapter, based on a review of recent research as well as data presented in this report, proposes four hypothetical pathways leading to suicide in clinical depression: (1) an acute pathway involving severe anxiety/agitation associated with high brain corticotrophin-releasing factor (crf or crh) levels, (2) trait baseline and reactivity hopelessness, (3) severe anhedonia, and (4) trait impulsiveness associated with low brain serotonin turnover and low total cholesterol as a possible peripheral correlate. |
1998-06-24 |
2023-08-12 |
Not clear |
| C C Meltzer, G Smith, S T DeKosky, B G Pollock, C A Mathis, R Y Moore, D J Kupfer, C F Reynold. Serotonin in aging, late-life depression, and Alzheimer's disease: the emerging role of functional imaging. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 18. issue 6. 1998-06-23. PMID:9571651. |
it has been further suggested that the age-related changes in 5-ht neurons may predispose the elderly to develop depression. |
1998-06-23 |
2023-08-12 |
human |