| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Sevcík, K Mase. [Serotonin and treatment of mental disorders. Present status and future perspectives]. Casopis lekaru ceskych. vol 136. issue 14. 1997-10-22. PMID:9340186. |
5-ht receptors play an important role in both schizophrenia and depression. |
1997-10-22 |
2023-08-12 |
Not clear |
| G Gerra, R Caccavari, A Zaimovic, M Palladino, B Chittolini, G Giucastro, D Maestri, C Monica, G Fertonani-Affini, R Delsignore, F Brambill. Serotonergic function in mothers of opioid addicts: correlation with comorbid depression. Acta psychiatrica Scandinavica. vol 96. issue 1. 1997-10-21. PMID:9259222. |
our data suggest that genetic 5-ht impairment is not involved in the pathogenesis of heroin addiction or codependence per se, and is probably linked to the presence of familial depression in comorbidity with the addictive disorder. |
1997-10-21 |
2023-08-12 |
human |
| P Andiné, L Rönnbäck, B Järvhol. Successful use of a selective serotonin reuptake inhibitor in a patient with multiple chemical sensitivities. Acta psychiatrica Scandinavica. vol 96. issue 1. 1997-10-21. PMID:9259230. |
a 53-year-old man with multiple chemical sensitivities (mcs) received the selective serotonin reuptake inhibitor (ssri) citalopram for treatment of depression. |
1997-10-21 |
2023-08-12 |
Not clear |
| J D Amsterdam, F García-España, M Rosenzwei. Clomipramine augmentation in treatment-resistant depression. Depression and anxiety. vol 5. issue 2. 1997-10-21. PMID:9262938. |
in depression that is resistant to tricyclic antidepressant (tca) therapy, the substitution of a selective serotonin re-uptake inhibitor (ssri), clomipramine, or a monoamine oxidase (mao) inhibitor has been recommended. |
1997-10-21 |
2023-08-12 |
Not clear |
| A J Clear. Reduced whole blood serotonin in major depression. Depression and anxiety. vol 5. issue 2. 1997-10-21. PMID:9262942. |
reduced whole blood serotonin in major depression. |
1997-10-21 |
2023-08-12 |
human |
| A J Clear. Reduced whole blood serotonin in major depression. Depression and anxiety. vol 5. issue 2. 1997-10-21. PMID:9262942. |
whole blood serotonin (wbs) was measured in 17 patients with dsm-iii-r major depression and compared to a healthy control group of 57. |
1997-10-21 |
2023-08-12 |
human |
| A J Clear. Reduced whole blood serotonin in major depression. Depression and anxiety. vol 5. issue 2. 1997-10-21. PMID:9262942. |
since blood serotonin is primarily produced peripherally, these results suggest that some aspect of peripheral serotonin metabolism is abnormal in major depression. |
1997-10-21 |
2023-08-12 |
human |
| J Röschke, P Kögel, R Schlösser, P Wagner, K Mann, W Rossbach, O Benker. Analysis of sleep EEG microstructure in subchronic paroxetine treatment of healthy subjects. Psychopharmacology. vol 132. issue 1. 1997-10-20. PMID:9272758. |
paroxetine is a selective and potent serotonin reuptake inhibitor and its efficacy for the treatment of depression has been proven. |
1997-10-20 |
2023-08-12 |
human |
| J P Gardner, C A Fornal, B L Jacob. Effects of sleep deprivation on serotonergic neuronal activity in the dorsal raphe nucleus of the freely moving cat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 17. issue 2. 1997-10-17. PMID:9252982. |
since most pharmacological treatments for depression increase brain serotonin neurotransmission, the purpose of the present study was to determine whether tsd increases the activity of serotonergic neurons in the dorsal raphe nucleus (drn) in cats. |
1997-10-17 |
2023-08-12 |
cat |
| O C Meijer, R V Van Oosten, E R De Kloe. Elevated basal trough levels of corticosterone suppress hippocampal 5-hydroxytryptamine(1A) receptor expression in adrenally intact rats: implication for the pathogenesis of depression. Neuroscience. vol 80. issue 2. 1997-10-17. PMID:9284345. |
elevated basal trough levels of corticosterone suppress hippocampal 5-hydroxytryptamine(1a) receptor expression in adrenally intact rats: implication for the pathogenesis of depression. |
1997-10-17 |
2023-08-12 |
human |
| O C Meijer, R V Van Oosten, E R De Kloe. Elevated basal trough levels of corticosterone suppress hippocampal 5-hydroxytryptamine(1A) receptor expression in adrenally intact rats: implication for the pathogenesis of depression. Neuroscience. vol 80. issue 2. 1997-10-17. PMID:9284345. |
we propose therefore that this suppressive effect on 5-hydroxytryptamine(1a) receptor expression involves enhanced occupation of mineralocorticoid receptors, under a condition of elevated basal trough corticosteroid levels as is commonly observed in human depression. |
1997-10-17 |
2023-08-12 |
human |
| A Braconnier, A Jeannea. [Anxiety, aggression, agitation and depression: psychopathologic aspects]. L'Encephale. vol 23 Spec No 3. 1997-10-15. PMID:9333560. |
the fourth model is based on the existence of a specific biological constraint related to abnormalities of serotonin metabolism, to which dysregulation of anxious and aggressive-impulsive behavior patterns during depression are considered related. |
1997-10-15 |
2023-08-12 |
Not clear |
| A Braconnier, A Jeannea. [Anxiety, aggression, agitation and depression: psychopathologic aspects]. L'Encephale. vol 23 Spec No 3. 1997-10-15. PMID:9333560. |
in conclusion, it may be considered that several models, in particular that of reaction to separation, may, at least in part, account for "positive-expression" depression, but that at least two questions have still to be answered: that regarding the relationships between depression and personality, and that concerning the relationships between the psychopathological constraints related to serotonin metabolism dysfunction and the "positive" expressions. |
1997-10-15 |
2023-08-12 |
Not clear |
| A Płaźnik, M Jessa, M Naza. The behavioral effects of NMDA antagonists in serotonin depleted rats. Pharmacology, biochemistry, and behavior. vol 58. issue 1. 1997-09-30. PMID:9264085. |
on the other hand, antagonism of cgp 37849-caused motor depression can be explained by the lowering influence of 5,7-dht on serotonin content. |
1997-09-30 |
2023-08-12 |
rat |
| L Dye, J E Blundel. Menstrual cycle and appetite control: implications for weight regulation. Human reproduction (Oxford, England). vol 12. issue 6. 1997-09-24. PMID:9221991. |
the premenstrual phase can be considered as a time when women are especially vulnerable to overconsumption, food craving and depression; this is often associated with low serotonin activity. |
1997-09-24 |
2023-08-12 |
Not clear |
| E Di Pasquale, A Lindsay, J Feldman, R Monteau, G Hilair. Serotonergic inhibition of phrenic motoneuron activity: an in vitro study in neonatal rat. Neuroscience letters. vol 230. issue 1. 1997-09-24. PMID:9259456. |
results from phrenic motoneuron whole cell recordings do not reject a presynaptic location of the 5-ht receptors responsible for this depression. |
1997-09-24 |
2023-08-12 |
rat |
| J K McQueen, H Wilson, G Fin. Estradiol-17 beta increases serotonin transporter (SERT) mRNA levels and the density of SERT-binding sites in female rat brain. Brain research. Molecular brain research. vol 45. issue 1. 1997-08-27. PMID:9105666. |
together with our previous findings, they also suggest that the sex differences in depression and the apparent psychotropic effect of e2 may be due to the action of e2 on the serotonin transporter as well as 5-ht2a receptors. |
1997-08-27 |
2023-08-12 |
rat |
| J L Yau, J Noble, J Widdowson, J R Seck. Impact of adrenalectomy on 5-HT6 and 5-HT7 receptor gene expression in the rat hippocampus. Brain research. Molecular brain research. vol 45. issue 1. 1997-08-27. PMID:9105690. |
both glucocorticoid excess and decreased serotonergic (5-ht) transmission may cause depression. |
1997-08-27 |
2023-08-12 |
rat |
| P J Goodnick, A Kumar, J H Henry, V M Buki, R B Goldber. Sertraline in coexisting major depression and diabetes mellitus. Psychopharmacology bulletin. vol 33. issue 2. 1997-08-20. PMID:9230640. |
results indicated (1) significant improvement in mean ham-d (22.6 +/- 3.4 to 4.9 +/- 5.9, p < .001) and in mean beck depression inventory (bdi) scores (21.9 +/- 10.5 to 12.7 +/- 8.3, p < .001); (2) fall in platelet serotonin (5-ht) content (79.7 +/- 22.5 to 13.6 +/- 12.7 ng/10(8) platelets, p < .001); (3) correlation of baseline platelet 5-ht content with response to sertraline by bdi scores (r = 0.51, p < .05); (4) improved dietary compliance for those with baseline value below 70 percent (59.7% to 69.1%, p < .005); and (5) 13 of 17 patients with baseline glycosylated hemoglobin a (hba1c) levels greater than 8.0, showed a reduction (p = .018). |
1997-08-20 |
2023-08-12 |
Not clear |
| Y De Sme. [Indications for new antidepressants with reference to ICD-10: a waggish question or the future of psychiatry?]. L'Encephale. vol 23. issue 2. 1997-08-19. PMID:9264934. |
the pharmacology of depression recently grows rich from "new" antidepressive agents, having selective monoaminergic activity: selective serotonin presynaptic reuptake inhibition ("ssris"), selective reversible inhibition of the monoamine oxidase a ("rimas"), selective dopaminergic or noradrenergic agents. |
1997-08-19 |
2023-08-12 |
Not clear |