| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Yoshida, H Higuchi, M Kamata, M Yoshimoto, T Shimizu, Y Hishikaw. Single and repeated electroconvulsive shocks activate dopaminergic and 5-hydroxytryptaminergic neurotransmission in the frontal cortex of rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 22. issue 2. 1998-08-11. PMID:9608612. |
these results suggest that the activating effect of repeated ect on 5-hydroxytryptaminergic (5-ht) and da neurotransmission, (especially on 5-ht neurotransmission), is significant in improving depression both in patients with parkinson's disease (pd) and in those who do not suffer from pd. |
1998-08-11 |
2023-08-12 |
rat |
| P Sandor, B Baker, J Irvine, P Dorian, D McKessok, S Mendlowit. Effectiveness of fluoxetine and doxepin in treatment of melancholia in depressed patients. Depression and anxiety. vol 7. issue 2. 1998-08-04. PMID:9614594. |
it has been suggested that serotonin reuptake inhibitors (ssris) may be less effective than tricyclic antidepressants (tcas) in treatment of melancholic depression. |
1998-08-04 |
2023-08-12 |
Not clear |
| K Beliles, A Stoudemir. Psychopharmacologic treatment of depression in the medically ill. Psychosomatics. vol 39. issue 3. 1998-08-04. PMID:9664784. |
while in the past antidepressant drug selection was limited by the almost sole availability of the tricyclic antidepressants, newer drugs such as selective serotonin reuptake inhibitors, bupropion, and venlafaxine have vastly simplified treating depression in the medically ill. |
1998-08-04 |
2023-08-12 |
Not clear |
| F R Sallee, R Hilal, D Dougherty, K Beach, L Nesbit. Platelet serotonin transporter in depressed children and adolescents: 3H-paroxetine platelet binding before and after sertraline. Journal of the American Academy of Child and Adolescent Psychiatry. vol 37. issue 7. 1998-07-29. PMID:9666634. |
to evaluate serotonin transporter protein (5htpr) binding in platelets from children and adolescents with major depression (mdd) compared to normal controls using the selective ligand 3h-paroxetine. |
1998-07-29 |
2023-08-12 |
Not clear |
| M Horni. Addressing comorbidity in adults with attention-deficit/hyperactivity disorder. The Journal of clinical psychiatry. vol 59 Suppl 7. 1998-07-29. PMID:9680055. |
serotonin and norepinephrine are implicated in major depression and anxiety disorders, while self-medication for dopamine dysfunction may relate to substance abuse. |
1998-07-29 |
2023-08-12 |
Not clear |
| Reports from the Canadian Coordinating Office for Health Technology Assessment (CCOHTA). Selective serotonin reuptake inhibitors for major depression. International journal of technology assessment in health care. vol 14. issue 2. 1998-07-17. PMID:9611913. |
selective serotonin reuptake inhibitors for major depression. |
1998-07-17 |
2023-08-12 |
Not clear |
| N E Rosenthal, C M Mazzanti, R L Barnett, T A Hardin, E H Turner, G K Lam, N Ozaki, D Goldma. Role of serotonin transporter promoter repeat length polymorphism (5-HTTLPR) in seasonality and seasonal affective disorder. Molecular psychiatry. vol 3. issue 2. 1998-07-16. PMID:9577843. |
the short (s), as opposed to the long (l), allele of the 5-ht transporter linked polymorphism (5-httlpr) has been associated with neuroticism and depression. |
1998-07-16 |
2023-08-12 |
Not clear |
| C Houc. An open-label pilot study of fluvoxamine for mixed anxiety-depression. Psychopharmacology bulletin. vol 34. issue 2. 1998-07-14. PMID:9641005. |
fluvoxamine, a selective serotonin reuptake inhibitor (ssri) approved for the treatment of obsessive-compulsive disorder, was studied for its effectiveness in treating anxiety and depression simultaneously during an 8-week, open-label trial of patients with mad. |
1998-07-14 |
2023-08-12 |
Not clear |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
neurobiology of serotonin in depression and suicide. |
1998-06-24 |
2023-08-12 |
human |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
alterations in serotonin neurotransmission have been implicated in the pathophysiology of major depression and suicide. |
1998-06-24 |
2023-08-12 |
human |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
altered signal transduction in cerebral cortex and altered regulation of serotonin neurons in the dr may be important in the pathophysiology of major depression and suicide. |
1998-06-24 |
2023-08-12 |
human |
| J Fawcett, K A Busch, D Jacobs, H M Kravitz, L Fog. Suicide: a four-pathway clinical-biochemical model. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616805. |
this chapter, based on a review of recent research as well as data presented in this report, proposes four hypothetical pathways leading to suicide in clinical depression: (1) an acute pathway involving severe anxiety/agitation associated with high brain corticotrophin-releasing factor (crf or crh) levels, (2) trait baseline and reactivity hopelessness, (3) severe anhedonia, and (4) trait impulsiveness associated with low brain serotonin turnover and low total cholesterol as a possible peripheral correlate. |
1998-06-24 |
2023-08-12 |
Not clear |
| C C Meltzer, G Smith, S T DeKosky, B G Pollock, C A Mathis, R Y Moore, D J Kupfer, C F Reynold. Serotonin in aging, late-life depression, and Alzheimer's disease: the emerging role of functional imaging. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 18. issue 6. 1998-06-23. PMID:9571651. |
it has been further suggested that the age-related changes in 5-ht neurons may predispose the elderly to develop depression. |
1998-06-23 |
2023-08-12 |
human |
| P Moore, C Gillin, T Bhatti, A DeModena, E Seifritz, C Clark, S Stahl, M Rapaport, J Kelso. Rapid tryptophan depletion, sleep electroencephalogram, and mood in men with remitted depression on serotonin reuptake inhibitors. Archives of general psychiatry. vol 55. issue 6. 1998-06-23. PMID:9633672. |
rapid tryptophan depletion, sleep electroencephalogram, and mood in men with remitted depression on serotonin reuptake inhibitors. |
1998-06-23 |
2023-08-12 |
human |
| C Sur, H Betz, P Schlos. Distinct effects of imipramine on 5-hydroxytryptamine uptake mediated by the recombinant rat serotonin transporter SERT1. Journal of neurochemistry. vol 70. issue 6. 1998-06-05. PMID:9603221. |
tricyclic and nontricyclic serotonin [5-hydroxytryptamine (5-ht)] uptake inhibitors are widely used for the treatment of depression. |
1998-06-05 |
2023-08-12 |
rat |
| S D Silberstei. Comprehensive management of headache and depression. Cephalalgia : an international journal of headache. vol 18 Suppl 21. 1998-05-21. PMID:9533672. |
while tricyclic antidepressants may be more effective for migraine, selective serotonin reuptake inhibitors are just as effective for depression and have fewer side effects. |
1998-05-21 |
2023-08-12 |
Not clear |
| R A Furlong, L Ho, C Walsh, J S Rubinsztein, S Jain, E S Paykel, D F Easton, D C Rubinsztei. Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders. American journal of medical genetics. vol 81. issue 1. 1998-05-13. PMID:9514589. |
the serotonin transporter is a compelling candidate gene to examine in bipolar and unipolar affective disorder, since drugs that specifically inhibit the serotonin transporter can successfully treat depression. |
1998-05-13 |
2023-08-12 |
Not clear |
| T J Cleopha. Depression and myocardial infarction: implications for medical prognosis and options for treatment. The Netherlands journal of medicine. vol 52. issue 2. 1998-05-13. PMID:9557532. |
the selective serotonin reuptake inhibitors lack arrhythmogenic effects, and have a beneficial effect in addition to depression on psychological factors, such as anxiety and mood disturbances, which are not uncommon in post-mi patients. |
1998-05-13 |
2023-08-12 |
Not clear |
| b' N Pivac, M Jakovljevi\\xc4\\x87, D M\\xc3\\xbcck-Seler, Z Brzovi\\xc4\\x8. Hypothalamic-pituitary-adrenal axis function and platelet serotonin concentrations in depressed patients. Psychiatry research. vol 73. issue 3. 1998-04-30. PMID:9481804.' |
our results suggest that plasma cortisol and platelet 5-ht concentrations might serve as independent biological markers for different subtypes of depression. |
1998-04-30 |
2023-08-12 |
human |
| E Schulz, C Fleischhaker, H W Clement, H Remschmid. Blood biogenic amines during clozapine treatment of early-onset schizophrenia. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 10. 1998-04-29. PMID:9503259. |
during long-term treatment, higher serotonin levels were associated with significantly fewer negative symptoms of schizophrenia, whereas higher mhpg levels were correlated with less depression. |
1998-04-29 |
2023-08-12 |
human |