| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Schmitz, T Gloveli, R M Empson, U Heineman. Potent depression of stimulus evoked field potential responses in the medial entorhinal cortex by serotonin. British journal of pharmacology. vol 128. issue 1. 1999-11-22. PMID:10498859. |
potent depression of stimulus evoked field potential responses in the medial entorhinal cortex by serotonin. |
1999-11-22 |
2023-08-12 |
Not clear |
| D Schmitz, T Gloveli, R M Empson, U Heineman. Potent depression of stimulus evoked field potential responses in the medial entorhinal cortex by serotonin. British journal of pharmacology. vol 128. issue 1. 1999-11-22. PMID:10498859. |
depression of field potential responses by serotonin was associated with a significant increase in paired-pulse facilitation from 1.15 to 1.88. |
1999-11-22 |
2023-08-12 |
Not clear |
| D Schmitz, T Gloveli, R M Empson, U Heineman. Potent depression of stimulus evoked field potential responses in the medial entorhinal cortex by serotonin. British journal of pharmacology. vol 128. issue 1. 1999-11-22. PMID:10498859. |
depression of isolated ampa-receptor mediated epscs by serotonin as well as fenfluramine was associated with an increase in paired pulse facilitation, indicating a presynaptic locus of action. |
1999-11-22 |
2023-08-12 |
Not clear |
| B J Stanford, S C Stanfor. Postoperative delirium indicating an adverse drug interaction involving the selective serotonin reuptake inhibitor, paroxetine? Journal of psychopharmacology (Oxford, England). vol 13. issue 3. 1999-11-19. PMID:10512094. |
the patient had not been prescribed neuroleptics but, before surgery, she had been taking the selective serotonin reuptake inhibitor, paroxetine, to relieve her depression. |
1999-11-19 |
2023-08-12 |
Not clear |
| C M Yang, C T Chiu, C C Wang, H L Tsao, L W Fa. Forskolin inhibits 5-hydroxytryptamine-induced phosphoinositide hydrolysis and Ca+2 Mobilisation in canine cultured aorta smooth muscle cells. Cellular signalling. vol 11. issue 9. 1999-11-19. PMID:10530879. |
the inhibitory effect of forskolin resulted from both a depression of the maximal response and a shift to the right of the concentration-effect curves of 5-ht in these responses. |
1999-11-19 |
2023-08-12 |
Not clear |
| D A Streja, R L Hui, E Streja, J S McComb. Selective contracting and patient outcomes: a case study of formulary restrictions for selective serotonin reuptake inhibitor antidepressants. The American journal of managed care. vol 5. issue 9. 1999-11-18. PMID:10621079. |
many health maintenance organizations (hmos) have selected 1 or 2 selective serotonin reuptake inhibitors (ssris) as their preferred drug for treating depression. |
1999-11-18 |
2023-08-12 |
Not clear |
| D A Sclar, T L Skaer, L M Robison, R S Gali. Economic appraisal of citalopram in the management of single-episode depression. Journal of clinical psychopharmacology. vol 19. issue 5 Suppl 1. 1999-11-10. PMID:10507508. |
a retrospective intent-to-treat analysis (n = 1,339) was conducted to discern the natural course of antidepressant use and direct health service expenditures for the treatment of single-episode depression (dsm-iv code 296.20) among patients initiating antidepressant pharmacotherapy with either a tricyclic antidepressant (tca) (amitriptyline, n = 237) or a selective serotonin reuptake inhibitor (ssri) (citalopram, n = 71; fluoxetine, n = 411; paroxetine, n = 334; or sertraline, n = 286). |
1999-11-10 |
2023-08-12 |
Not clear |
| A H Rezvani, D H Overstreet, Y Yang, E Clar. Attenuation of alcohol intake by extract of Hypericum perforatum (St. John's Wort) in two different strains of alcohol-preferring rats. Alcohol and alcoholism (Oxford, Oxfordshire). vol 34. issue 5. 1999-11-09. PMID:10528812. |
depression and alcoholism have some neurochemical similarities, such as low brain serotonin activities. |
1999-11-09 |
2023-08-12 |
human |
| G Chouinard, B Saxena, M C Bélanger, A Ravindran, D Bakish, L Beauclair, P Morris, N P Vasavan Nair, R Manchanda, R Reesal, R Remick, M C O'Neil. A Canadian multicenter, double-blind study of paroxetine and fluoxetine in major depressive disorder. Journal of affective disorders. vol 54. issue 1-2. 1999-10-26. PMID:10403145. |
in a 12-week randomized, multicenter, double-blind trial, the antidepressant and anxiolytic efficacy of the selective serotonin reuptake inhibitors paroxetine and fluoxetine was compared in patients with moderate to severe depression. |
1999-10-26 |
2023-08-12 |
Not clear |
| A Lucchelli, M G Santagostino-Barbone, E Masoero, P Baiardi, M Tonin. Influence of fluoxetine and litoxetine on 5-HT4 receptor-mediated relaxation in the rat isolated oesophagus. Fundamental & clinical pharmacology. vol 13. issue 3. 1999-10-22. PMID:10392309. |
in tissues from untreated rats, litoxetine (1 microm) increased the relaxant effects of 5-ht, while in tissues from pcpa treated animals it exerted a small but significant depression of the maximal response to 5-ht, without changing its potency value. |
1999-10-22 |
2023-08-12 |
rat |
| K Borbely, R A Brooks, D F Wong, R S Burns, P Cumming, A Gjedde, G Di Chir. NMSP binding to dopamine and serotonin receptors in MPTP-induced parkinsonism: relation to dopa therapy. Acta neurologica Scandinavica. vol 100. issue 1. 1999-10-21. PMID:10416511. |
low synaptic serotonin may explain the depression seen in some patients on dopa for parkinson's disease. |
1999-10-21 |
2023-08-12 |
Not clear |
| F Duval, M C Mokrani, P Bailey, H Correa, T S Diep, M A Crocq, J P Mache. Thyroid axis activity and serotonin function in major depressive episode. Psychoneuroendocrinology. vol 24. issue 7. 1999-10-21. PMID:10451906. |
recent studies in depression have reported alterations in both hypothalamic-pituitary-thyroid (hpt) axis activity and serotonin (5-ht) function; however, the functional relationships between the two systems have not been well defined in patients with major depressive episode. |
1999-10-21 |
2023-08-12 |
Not clear |
| G Juckel, A Mendlin, B L Jacob. Electrical stimulation of rat medial prefrontal cortex enhances forebrain serotonin output: implications for electroconvulsive therapy and transcranial magnetic stimulation in depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 3. 1999-10-19. PMID:10457536. |
electrical stimulation of rat medial prefrontal cortex enhances forebrain serotonin output: implications for electroconvulsive therapy and transcranial magnetic stimulation in depression. |
1999-10-19 |
2023-08-12 |
rat |
| G Racagn. Noradrenaline and serotonin in depression: consensus and controversies. International clinical psychopharmacology. vol 14 Suppl 1. 1999-10-19. PMID:10468321. |
noradrenaline and serotonin in depression: consensus and controversies. |
1999-10-19 |
2023-08-12 |
Not clear |
| G Racagni, N Brunell. Physiology to functionality: the brain and neurotransmitter activity. International clinical psychopharmacology. vol 14 Suppl 1. 1999-10-19. PMID:10468322. |
the monoamine hypothesis of depression proposes that the biological basis for depression is a deficiency in the neurotransmitters serotonin or noradrenaline, or both. |
1999-10-19 |
2023-08-12 |
Not clear |
| G Racagni, N Brunell. Physiology to functionality: the brain and neurotransmitter activity. International clinical psychopharmacology. vol 14 Suppl 1. 1999-10-19. PMID:10468322. |
the selective serotonin reuptake inhibitors in particular have made a significant contribution to our understanding of the role of serotonin in depression. |
1999-10-19 |
2023-08-12 |
Not clear |
| J Mendlewic. Predicting response: serotonin reuptake inhibition. International clinical psychopharmacology. vol 14 Suppl 1. 1999-10-19. PMID:10468324. |
the introduction of selective serotonin reuptake inhibitors (ssris) has helped clarify our understanding of the actions of serotonin in depression. |
1999-10-19 |
2023-08-12 |
Not clear |
| S A Montgomer. Predicting response: noradrenaline reuptake inhibition. International clinical psychopharmacology. vol 14 Suppl 1. 1999-10-19. PMID:10468325. |
for the past decade, the role of noradrenaline in depression has been somewhat neglected in favour of serotonin. |
1999-10-19 |
2023-08-12 |
Not clear |
| A Frisch, D Postilnick, R Rockah, E Michaelovsky, S Postilnick, E Birman, N Laor, B Rauchverger, A Kreinin, M Poyurovsky, M Schneidman, I Modai, R Weizma. Association of unipolar major depressive disorder with genes of the serotonergic and dopaminergic pathways. Molecular psychiatry. vol 4. issue 4. 1999-10-18. PMID:10483058. |
a line of evidence suggests the involvement of serotonin and dopamine neurotransmitters in the pathophysiology of depression. |
1999-10-18 |
2023-08-12 |
Not clear |
| M A Menza, B Palermo, R DiPaola, J I Sage, M H Rickett. Depression and anxiety in Parkinson's disease: possible effect of genetic variation in the serotonin transporter. Journal of geriatric psychiatry and neurology. vol 12. issue 2. 1999-10-15. PMID:10483924. |
depression and anxiety in parkinson's disease: possible effect of genetic variation in the serotonin transporter. |
1999-10-15 |
2023-08-12 |
Not clear |