| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B H Zorn, H Montgomery, K Pieper, M Gray, W D Steer. Urinary incontinence and depression. The Journal of urology. vol 162. issue 1. 1999-07-19. PMID:10379745. |
because descending serotonin pathways from the brain stem inhibit bladder contractions, we postulated that depression associated with altered serotonin function may predispose to urge incontinence. |
1999-07-19 |
2023-08-12 |
Not clear |
| J G van Amsterdam, A Opperhuize. Nitric oxide and biopterin in depression and stress. Psychiatry research. vol 85. issue 1. 1999-07-16. PMID:10195314. |
depression has been hypothesized to be related to the reduced biosynthesis of neurotransmitters such as serotonin, noradrenalin and dopamine. |
1999-07-16 |
2023-08-12 |
Not clear |
| R I Griffiths, E M Sullivan, R G Frank, M J Strauss, R J Herbert, J Clouse, H H Goldma. Medical resource use and cost of venlafaxine or tricyclic antidepressant therapy. Following selective serotonin reuptake inhibitor therapy for depression. PharmacoEconomics. vol 15. issue 5. 1999-07-16. PMID:10537966. |
following selective serotonin reuptake inhibitor therapy for depression. |
1999-07-16 |
2023-08-12 |
Not clear |
| S P Roose, E Spat. Treating depression in patients with ischaemic heart disease: which agents are best to use and to avoid? Drug safety. vol 20. issue 5. 1999-07-08. PMID:10348096. |
short term studies of the safety of other antidepressant agents, specifically amfebutamone (bupropion) and the selective serotonin (5-hydroxytryptamine; 5-ht) reuptake inhibitors (ssris) fluoxetine, paroxetine and sertraline, suggest that these medications have a benign cardiovascular profile in patients with depression and pre-existing cardiac disease. |
1999-07-08 |
2023-08-12 |
Not clear |
| A V Ravindran, J Griffiths, Z Merali, V J Knott, H Anisma. Influence of acute tryptophan depletion on mood and immune measures in healthy males. Psychoneuroendocrinology. vol 24. issue 1. 1999-07-06. PMID:10098222. |
lowering tryptophan levels by means of a tryptophan-deficient amino acid mixture, which reduced plasma tryptophan and serotonin (5-ht) levels, produced a lowering of mood in a subset of male subjects (that had no personal or family history of depression) relative to subjects that received a balanced amino acid mixture. |
1999-07-06 |
2023-08-12 |
human |
| A V Ravindran, J Griffiths, Z Merali, V J Knott, H Anisma. Influence of acute tryptophan depletion on mood and immune measures in healthy males. Psychoneuroendocrinology. vol 24. issue 1. 1999-07-06. PMID:10098222. |
correlational analyses revealed that the change of mood (particularly depression and anger) in subjects that received the tryptophan-free mixture was related to the extent of the tryptophan or 5-ht reductions. |
1999-07-06 |
2023-08-12 |
human |
| A V Ravindran, J Griffiths, Z Merali, V J Knott, H Anisma. Influence of acute tryptophan depletion on mood and immune measures in healthy males. Psychoneuroendocrinology. vol 24. issue 1. 1999-07-06. PMID:10098222. |
even if depression were related to immune disturbances, the mood and 5-ht alterations associated with this type of manipulation may be too brief to promote immune changes comparable with those ordinarily associated with severe or chronic depressive illness. |
1999-07-06 |
2023-08-12 |
human |
| P A Shapiro, F Lespérance, N Frasure-Smith, C M O'Connor, B Baker, J W Jiang, P Dorian, W Harrison, A H Glassma. An open-label preliminary trial of sertraline for treatment of major depression after acute myocardial infarction (the SADHAT Trial). Sertraline Anti-Depressant Heart Attack Trial. American heart journal. vol 137. issue 6. 1999-07-02. PMID:10347338. |
it is not known whether serotonin reuptake inhibitors would be safe and effective for patients with depression after myocardial infarction and whether such treatment would reduce mortality rates. |
1999-07-02 |
2023-08-12 |
Not clear |
| J Wu, G L Kramer, M Kram, M Steciuk, I L Crawford, F Pett. Serotonin and learned helplessness: a regional study of 5-HT1A, 5-HT2A receptors and the serotonin transport site in rat brain. Journal of psychiatric research. vol 33. issue 1. 1999-06-22. PMID:10094235. |
serotonin (5-ht) plays a central role in the neurochemistry of the learned helplessness animal model of depression. |
1999-06-22 |
2023-08-12 |
rat |
| D Q Xiao, J S Tang, B Yuan, H Ji. Inhibitory effects of 5-hydroxytryptamine microinjection into thalamic nucleus submedius on rat tail flick reflex are mediated by 5-HT2 receptors. Neuroscience letters. vol 260. issue 2. 1999-06-18. PMID:10025705. |
these results suggest that 5-ht application to the sm may activate sm neurons through the 5-ht2 receptors leading to activation of the brainstem descending inhibitory system via the vlo and depression of the nociceptive information at the spinal level. |
1999-06-18 |
2023-08-12 |
rat |
| R Bourdeaux, P Pannetier, D Desor, P R Lehr, C Younos, B Capolagh. [Effect of fluoxetine treatment on serotonin and MHPG in 32 patients with major depressive disorder]. L'Encephale. vol 25. issue 1. 1999-06-17. PMID:10205732. |
considering the concept that depressive disorders were not only resulting from activity of one neurotransmitter, possible interactions between the noradrenergic system and a selective serotonin uptake inhibitor, fluoxetine, were investigated in order to test the hypothesis of noradrenergic or serotonergic involvement in depression. |
1999-06-17 |
2023-08-12 |
human |
| A J Rothschild, K A Phillip. Selective serotonin reuptake inhibitors and delusional depression. The American journal of psychiatry. vol 156. issue 6. 1999-06-16. PMID:10360159. |
selective serotonin reuptake inhibitors and delusional depression. |
1999-06-16 |
2023-08-12 |
Not clear |
| J Neuger, A El Khoury, B F Kjellman, B Wahlund, A Aberg-Wistedt, R Stain-Malmgre. Platelet serotonin functions in untreated major depression. Psychiatry research. vol 85. issue 2. 1999-06-07. PMID:10220009. |
platelet serotonin functions in untreated major depression. |
1999-06-07 |
2023-08-12 |
human |
| J Neuger, A El Khoury, B F Kjellman, B Wahlund, A Aberg-Wistedt, R Stain-Malmgre. Platelet serotonin functions in untreated major depression. Psychiatry research. vol 85. issue 2. 1999-06-07. PMID:10220009. |
the uptake of [14c]5-ht, [3h]paroxetine and [3h]lsd binding was determined in platelets from 30 untreated patients with major depression and compared with corresponding variables from 30 healthy age-, sex- and season-matched control subjects. |
1999-06-07 |
2023-08-12 |
human |
| L W Maines, B J Keck, J E Smith, J M Lakosk. Corticosterone regulation of serotonin transporter and 5-HT1A receptor expression in the aging brain. Synapse (New York, N.Y.). vol 32. issue 1. 1999-06-01. PMID:10188639. |
as the serotonergic (5-hydroxytryptamine; 5-ht) system plays a major role in the etiology of depression, a loss of endocrine and neurotransmitter system interactions, including corticosterone regulation of 5-ht transporter (5-htt) and 5-ht receptor expression, may underlie age-related deficits in the regulation of the hypothalamic-pituitary-adrenal (hpa) axis and correlate with an increased incidence of depression with advancing age. |
1999-06-01 |
2023-08-12 |
rat |
| E F Espejo, F J Miñan. Prefrontocortical dopamine depletion induces antidepressant-like effects in rats and alters the profile of desipramine during Porsolt's test. Neuroscience. vol 88. issue 2. 1999-06-01. PMID:10197779. |
in conclusion, the results indicate that: (i) dopamine neurotransmission within the medial prefrontal cortex is a factor involved in depression, since dopamine reduction led to a low depression tonus; (ii) desipramine induces antidepression not only by enhancing prefrontocortical noradrenaline and serotonin neurotransmission, but also by blocking the normal increase in dopamine neurotransmission during a depressant situation; (iii) a selective enhancement of prefrontocortical serotonin neurotransmission mediates swimming; and (iv) a selectively augmented prefrontocortical noradrenaline activity mediates climbing during porsolt's test. |
1999-06-01 |
2023-08-12 |
rat |
| M Maes, I Libbrecht, F van Hunsel, D Campens, H Y Meltze. Pindolol and mianserin augment the antidepressant activity of fluoxetine in hospitalized major depressed patients, including those with treatment resistance. Journal of clinical psychopharmacology. vol 19. issue 2. 1999-06-01. PMID:10211920. |
the aims of this study were to examine whether pindolol, a serotonin (5-hydroxytryptamine [5-ht])-1a receptor antagonist, and mianserin, a 5-ht2a/c and alpha2-adrenoceptor (alpha2-ar) antagonist, may augment the clinical efficacy of fluoxetine, a selective serotonin reuptake inhibitor, and shorten the latency of onset of antidepressive activity in the treatment of major and treatment-resistant depression (trd). |
1999-06-01 |
2023-08-12 |
Not clear |
| A Bonci, R C Malenk. Properties and plasticity of excitatory synapses on dopaminergic and GABAergic cells in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 10. 1999-06-01. PMID:10234004. |
the relative contribution of nmda and non-nmda receptors to the synaptic currents recorded from the two cell types is the same as is the depression of synaptic transmission elicited by the application of adenosine, serotonin, or methionine enkephalin (met-enkephalin). |
1999-06-01 |
2023-08-12 |
Not clear |
| H Plein, M Ber. The platelet intracellular calcium response to serotonin and thrombin in patients with panic disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 9. issue 1-2. 1999-05-26. PMID:10082235. |
serotonin is implicated in both the biology of depression and anxiety. |
1999-05-26 |
2023-08-12 |
human |
| T R Einarson, S R Arikian, J Casciano, J J Doyl. Comparison of extended-release venlafaxine, selective serotonin reuptake inhibitors, and tricyclic antidepressants in the treatment of depression: a meta-analysis of randomized controlled trials. Clinical therapeutics. vol 21. issue 2. 1999-05-25. PMID:10211533. |
comparison of extended-release venlafaxine, selective serotonin reuptake inhibitors, and tricyclic antidepressants in the treatment of depression: a meta-analysis of randomized controlled trials. |
1999-05-25 |
2023-08-12 |
Not clear |